RESUMEN
BACKGROUND: A longitudinal cohort study was established to investigate the well-being of children born with cleft lip and/or palate (CL/P) during the COVID-19 pandemic, in Victoria, Australia. MATERIALS AND METHODS: The Royal Children's Hospital cleft service database was used to identify children aged between 4 and 17 years old born with an isolated CL/P. Families of eligible children who consented to participate were asked to complete the Strengths and Difficulties Questionnaire (SDQ) between October and December 2020 and again 6-month later. SDQ results from typically developing Australian children during the COVID-19 pandemic were utilized from a previously published study. RESULTS: 63 parents completed the baseline questionnaire, with 44 completing the 6-month follow-up. For participants at baseline, the mean age was 8.9 years, with 55% male. All outcome domains of the SDQ improved between baseline and timepoint 2, with the difference in total difficulties scores being statistically significant, indicating a reduction in total difficulties at timepoint 2, associated with the easing of COVID-19 restrictions. When compared with the Australian population during the COVID-19 pandemic, Victorian children born with CL/P had lower SDQ scores for all difficulties outcome domains, with statistically significant results for conduct problems, hyperactivity, peer problems and total difficulties, indicating fewer difficulties for children born with CL/P. CONCLUSIONS: Children born with CL/P experienced fewer difficulties when compared with the typically developing Australian population during the COVID-19 pandemic. The level of restrictions imposed because of the pandemic also had little influence on the well-being of these children.
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COVID-19 , Labio Leporino , Fisura del Paladar , Niño , Humanos , Masculino , Preescolar , Adolescente , Femenino , Labio Leporino/epidemiología , Fisura del Paladar/epidemiología , Estudios Longitudinales , Pandemias , Australia/epidemiología , COVID-19/epidemiologíaRESUMEN
The number of people forced to flee their homes and move around the world is increasing rapidly. Such refugee populations are not only more likely to have poor physical, mental and social health outcomes but also to experience difficulties accessing health services in their new country. In particular, children from refugee backgrounds are at increased risk of poor oral health which in time is associated with poor adult oral health and impacts on child health (e.g. growth and development) and well-being. To date, there is little evidence about the nature and extent of their oral health problems nor interventions to improve their oral health status. This article summarises the evidence surrounding the oral health status of children from refugee backgrounds. In addition, a systematic review of the international literature over the past 10 years is presented which identifies interventions to improve the oral health of these vulnerable paediatric populations. Based on this evidence, potential strategies available to dental service providers to optimise provision of responsive dental care are discussed.
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Atención Dental para Niños , Accesibilidad a los Servicios de Salud , Salud Bucal , Higiene Bucal , Refugiados , Adolescente , Niño , Preescolar , Conocimientos, Actitudes y Práctica en Salud , Promoción de la Salud , Humanos , Tamizaje Masivo/métodos , Enfermedades Dentales/diagnósticoRESUMEN
BACKGROUND: There is a lack of literature describing dental admissions in children particularly very young children. This paper describes dental and oral cavity admissions and associated factors in children under two years of age using total-population databases. METHODS: The data used for this study were extracted from population-based databases which are linkable with midwives' data collected on all births in Western Australia. Children born from 1980 to 1998 inclusive (n = 459,831) were followed until two years of age including data on deaths, hospital admissions, birth defects and intellectual disability. Dental admissions (by ICD-9 category) and associated factors were investigated. RESULTS: There were 1513 dental admissions occurring in 1459 of the children up to the age of two years. Children were most frequently admitted under ICD-9 category 521, which includes a hospital admission for dental caries (39% of all oral cavity admissions), followed by ICD-9 category 528 (29%), which includes diseases of the oral soft tissues. Univariate analysis indicated that those with intellectual disability (OR 2.10, 95%CI 1.40-3.16), birth defect (1.74, 1.45-2.09), residing in a region without fluoridated water (2.15, 1.72-2.69) being male (1.14, 1.03-1.26), those from rural areas (2.29, 2.07-2.54) and Indigenous children (4.45, 3.91-5.05) were significantly more likely to have had a dental admission. CONCLUSION: Using total-population data allowed us to describe the admissions in children under two years and associated factors while able to identify children with intellectual disability or birth defects.
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Hospitalización/estadística & datos numéricos , Enfermedades Estomatognáticas/epidemiología , Anomalías Congénitas/epidemiología , Caries Dental/epidemiología , Caries Dental/etiología , Femenino , Fluoruración/estadística & datos numéricos , Humanos , Lactante , Recién Nacido , Discapacidad Intelectual/complicaciones , Discapacidad Intelectual/epidemiología , Tiempo de Internación/estadística & datos numéricos , Masculino , Registro Médico Coordinado , Factores de Riesgo , Factores Sexuales , Enfermedades Estomatognáticas/etiología , Australia Occidental/epidemiologíaRESUMEN
OBJECTIVES: Hypomineralised second primary molars (HSPM) are common developmental enamel defects. The aims of this study were to use surface-level data to explore the clustering of HSPM at four levels (family, child, tooth, surface). METHODS: This study of 172 twin pairs was nested within the Peri/postnatal Epigenetic Twin Study. HSPM was measured by standardised oral examinations at age 6 years. Multilevel logistic regression models were fitted to assess the correlation structure of surface level data and variation in HSPM. The associations between surface level risk factors and HSPM were then explored using the multilevel logistic regression model using the best fitting correlation structure. RESULTS: The prevalence of HSPM was 68 (19.8%) children, with a total of 141 (10.3%) teeth and 264 tooth surfaces (6.3%) affected. Multilevel models revealed that a hierarchical structure accounting for correlation at the family, child and tooth level best accounted for the variation in HSPM. The estimated variances from the best fitting model (Model 3) were largest at the family level (12.27, 95% CI 6.68, 22.51) compared with 5.23 at the child level and 1.93 at the tooth level. Application of regression analysis utilising this three-level correlation structure identified tooth/surface level factors in addition to the previously identified familial and individual risk factors for HSPM. CONCLUSION: In addition to familial (environmental and genetic) and unique child-level factors, the aetiology of HSPM is likely to be influenced by local tooth-level factors.
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Hipoplasia del Esmalte Dental , Niño , Esmalte Dental , Hipoplasia del Esmalte Dental/epidemiología , Hipoplasia del Esmalte Dental/genética , Humanos , Diente Molar , Prevalencia , Diente PrimarioRESUMEN
Sub-optimal nutrition and dental caries are both common with significant short and long-term implications for child health and development. We applied twin statistical methods to explore the relationship between body mass index (BMI) and dental caries. We measured BMI at 18 months and six years of age and cumulative dental caries experience at six years in 344 twin children. Dental caries in primary teeth was categorised into 'any' or 'advanced' and BMI was analysed as both a continuous and categorical variable. Statistical analyses included multiple logistic regression using generalized estimating equations and within/between-pair analyses. There was no association between BMI and 'any' dental caries experience at either time-point, neither overall nor in within/between pair analyses. However, 'advanced' dental caries at six years was associated with a within-pair difference in BMI of -0.55 kg/m2 (95% CI -1.00, -0.11, p = 0.015). A within-pair increase of 1 kg/m2 in BMI was associated with a lower within-pair risk of advanced dental caries (OR 0.68, 95% CI 0.52, 0.90, p = 0.007). These findings reveal a possible causal relationship between lower BMI and dental caries. As dental outcomes were only measured at one time point, the direction of this potentially causal relationship is unclear.
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Caries Dental/epidemiología , Enfermedades en Gemelos/epidemiología , Índice de Masa Corporal , Niño , Femenino , Humanos , Lactante , Modelos Logísticos , Masculino , Estado NutricionalRESUMEN
Orofacial clefts are the most common craniofacial birth defects and one of the most common congenital malformations in humans. They require complex multidisciplinary treatment and are associated with elevated infant mortality and significant lifelong morbidity. The development of craniofacial structures is an exquisitely orchestrated process involving the coordinated growth of multiple, independently derived primordia. Perturbations impacting on the genesis or growth of these primordia may interfere with the proper morphogenesis of facial structures, resulting in clefting of the lip, the primary or secondary palate, or a combination of these sites. A variety of genetic approaches involving both human populations and animal models have greatly facilitated the search for genes involved in human clefting. In this article, we review the most prominent genes for orofacial clefts in the context of developmental pathways that shape the craniofacial complex. We highlight several Mendelian clefting syndromes that have provided valuable clues in identifying genes for the more common, isolated forms of clefting. Finally, we elaborate on a number of potential subclinical features (subphenotypes) associated with what have previously been diagnosed as 'isolated' clefts that may serve as additional markers for identifying individuals or families in whom there may be a greater risk of inheriting a cleft.
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Labio Leporino/genética , Fisura del Paladar/genética , Animales , Labio Leporino/embriología , Fisura del Paladar/embriología , Huesos Faciales/embriología , Perfilación de la Expresión Génica , Regulación del Desarrollo de la Expresión Génica , Genotipo , Humanos , Péptidos y Proteínas de Señalización Intercelular/genética , Desarrollo Maxilofacial/genética , Fenotipo , Factores de Transcripción/genéticaRESUMEN
Dental caries is one of the most common chronic diseases affecting individuals of all ages. Caries in the primary dentition is one of the main risk factors for caries in the permanent dentition. Preventing the development of the first carious lesion is fundamental not only to long term health and wellbeing but to reducing the burden of this disease on individuals, families and the community. Described as the developmental origins of health and disease, events from the prenatal period are increasingly recognised as having a significant impact on later health outcomes. While social and behavioural factors from this period have long been linked with oral health, emerging evidence of the influence of epigenetics and early life programming of microbiome and host response suggests that the prenatal period provides a timely opportunity for preventive interventions. Pregnancy is an ideal time to focus on health promoting activities as most women have regular interaction with health care professionals who can target risk factors before the onset of disease. This paper summarizes contemporary understanding of the role of pre- and perinatal factors on child oral health and describes how this evidence might be used by all health professionals to ensure infants start life ahead in the oral health game.
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Caries Dental , Salud Bucal , Atención Prenatal , Niño , Caries Dental/prevención & control , Dentición Permanente , Femenino , Humanos , Lactante , Atención Perinatal , Embarazo , Factores de Riesgo , Diente PrimarioRESUMEN
The etiology of hypomineralized second primary molars (HSPM) is unclear, but genetic and environmental factors have been proposed. The aim of this study was to investigate the relative contribution of genes and environment to the etiology of HSPM and to identify potential environmental risk factors in a longitudinal twin cohort. Children from twin pregnancies ( N = 250) were recruited antenatally, and detailed demographic, health, and phenotypic data were collected at recruitment, 24- and 36-wk gestation, birth, and 18 mo of age. 25-Hydroxyvitamin D was quantified for mothers at 28-wk gestation and infants at birth. Dental examinations were conducted on the twins at 6 y of age to determine the presence, severity, and extent of HSPM per standardized criteria. To investigate associations of environmental risk factors with HSPM, multiple logistic regression models were fitted with generalized estimating equations to adjust for twin correlation. Within- and between-pair analyses were performed for unshared continuous variables: birthweight and birth 25-hydroxyvitamin D. Twin-twin concordance for monozygotic (MZ) and dizygotic (DZ) pairs was calculated and compared after adjusting for identified risk factors. A total of 344 twins underwent the 6-y-old dental assessment; HSPM occurred in 68 (19.8%). After adjusting for potential confounders, vitamin D levels at birth, infantile eczema, dizygosity, in vitro fertilization, socioeconomic position, and maternal smoking beyond the first trimester of pregnancy demonstrated the strongest associations with HSPM. Overall concordance for HSPM was 0.47 (95% CI, 0.32 to 0.62) with weak evidence ( P = 0.078) of higher concordance in MZ twins (0.63; 95% CI, 0.38 to 0.89) as compared with DZ twins (0.41; 95% CI, 0.24 to 0.58). After adjusting for known risk factors, there was no evidence ( P = 0.172) for an additive genetic influence. These findings suggest that shared and unshared environmental factors, such as maternal smoking later in pregnancy and infantile eczema, are important in the etiology of HSPM.
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Hipoplasia del Esmalte Dental/epidemiología , Diente Primario , Gemelos Dicigóticos/estadística & datos numéricos , Gemelos Monocigóticos/estadística & datos numéricos , Australia , Niño , Hipoplasia del Esmalte Dental/etiología , Femenino , Humanos , Diente Molar , Embarazo , Prevalencia , Estudios ProspectivosRESUMEN
BACKGROUND: Worldwide, molar incisor hypomineralization (MIH) affects a substantial number of children and impacts greatly on treatment need and dental anxiety, yet there is little information regarding its prevalence, aetiology, presentation and management. The aims of this survey were to assess awareness and perceptions of the Australian paediatric dental community concerning MIH, and to describe current treatment strategies. METHODS: A questionnaire, based upon a previous European study, was sent to all Australian members of the Australian and New Zealand Society of Paediatric Dentistry. The questionnaire sought information on clinical experience of MIH, knowledge of prevalence, aetiology and contemporary management strategies for MIH. RESULTS: One hundred and thirty useable responses were received (58.8 per cent response rate) of which 36 were paediatric dentists, 6 paediatric dentistry postgraduate students, 59 general dentists, 14 dental therapists and 14 specialists in other fields. Most (98.5 per cent) respondents were familiar with MIH and encountered it in their practice. The majority (73.1 per cent) estimated that MIH occurred in between 5 to 25 per cent of their clinical practice and almost all (96.9 per cent) considered it to be a clinical problem. Only 16.9 per cent of respondents were aware of existing prevalence data and 96.9 per cent valued investigating the prevalence of MIH. No consensus existed regarding the aetiology of MIH or its restorative management. Paediatric dentists used preformed crowns significantly more than non-specialists, however glass ionomer cements were popular with all groups. CONCLUSIONS: MIH is a well recognized and widely encountered clinical condition. MIH presents several clinical problems and is worthy of further investigation. Currently, no consistent clinical management strategies are utilized.
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Actitud del Personal de Salud , Incisivo/patología , Diente Molar/patología , Odontología Pediátrica , Desmineralización Dental/diagnóstico , Australia , Resinas Compuestas , Coronas , Asistentes Dentales/educación , Restauración Dental Permanente/métodos , Educación de Posgrado en Odontología , Odontología General , Cementos de Ionómero Vítreo , Humanos , Nueva Zelanda , Ortodoncia/educación , Odontología Pediátrica/educación , Especialidades Odontológicas/educación , Desmineralización Dental/etiología , Desmineralización Dental/terapiaRESUMEN
BACKGROUND: Little is known about the oral health of children under the age of four years. The determinants of early childhood caries (ECC) in this young age group are also not well understood despite a growing recognition that early interventions may deliver the greatest benefits. The aim of this study was to examine the oral health-related knowledge, attitudes and reported behaviours of parents of children aged 12-24 months living in rural areas of Victoria, Australia. METHODS: A robust theoretical model was utilized to identify oral health-related behaviours and their antecedent and reinforcing conditions within the context of this specific population group. Two hundred and ninety-four parent/child dyads were recruited through their maternal and child health nurses as part of a larger intervention trial. Parents completed a self-report questionnaire. RESULTS: Knowledge regarding risk and protective factors amongst parents was variable and sometimes at odds with contemporary evidence. Knowledge of the role of early infection with S. mutans was very low, with high levels of behaviours that may promote early transmission reported. Tooth cleaning was reported by most parents at least sometimes, however a large proportion lacked confidence and this was significantly related to the frequency of the cleaning. Parents were confused about the fluoride status of their water supplies. Most parents believed fluoride toothpaste reduced the risk of ECC but did not know whether it should be used with toddlers. CONCLUSIONS: The results of this study have implications for efforts to prevent dental decay in this very young age group. Health care professionals other than dentists need support to provide information and promote confidence with regard to optimal fluoride exposure. Attention should also be given to the contribution of early contact with particular bacteria in oral health education and promotion programmes.
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Actitud Frente a la Salud , Conductas Relacionadas con la Salud , Conocimientos, Actitudes y Práctica en Salud , Salud Bucal , Relaciones Padres-Hijo , Padres/psicología , Salud Rural , Adulto , Cariostáticos/análisis , Cariostáticos/uso terapéutico , Preescolar , Caries Dental/microbiología , Caries Dental/prevención & control , Femenino , Fluoruros/análisis , Fluoruros/uso terapéutico , Educación en Salud Dental , Humanos , Lactante , Control Interno-Externo , Masculino , Factores de Riesgo , Autoimagen , Streptococcus mutans/fisiología , Cepillado Dental , Pastas de Dientes/uso terapéutico , Victoria , Abastecimiento de Agua/análisisRESUMEN
BACKGROUND: Maternal behaviours during pregnancy are likely to play a significant role in the development of dental caries in children. Although midwives are well placed to discuss oral health and provide information to women, dental attendance by women during pregnancy is minimal. This study aimed to explore midwives' experience of facilitating pregnant women's access to dental care and to document women's experience of receiving dental information and care during pregnancy. METHODS: Focus groups with midwives and telephone interviews with women who were referred to Monash Health Dental Services were conducted to explore their perspectives and experiences. The qualitative data was thematically analysed. RESULTS: Three focus groups with 13 midwives and telephone interviews with eight women who recently gave birth were conducted. Three key themes were identified: maternal oral health knowledge; barriers to accessing dental information and care during pregnancy; and suggested recommendations. CONCLUSIONS: This study highlighted the barriers that exist for midwives to discuss oral health with women and refer women to dental care, and women's experiences of accessing dental care during pregnancy. Ongoing collaboration between the maternity and dental services is required to strengthen midwives' knowledge, confidence and practise in supporting women to access dental care during pregnancy.
RESUMEN
Congenital midline cervical cleft (CMCC) is a rare condition that consists of a cutaneous midline neck lesion with a sinus extending inferiorly towards the sternum. A fibrous band that extends superiorly to the mandible is a consistent feature of the condition. Restriction of growth of the mandible, possibly due to incomplete removal of the band, is the most significant long-term problem. It remains unclear whether early removal of the fibrous band might allow catch-up growth of the mandible. This study utilized non-invasive three-dimensional photographs to objectively evaluate the facial growth of six CMCC patients. The growth of these CMCC patients was compared to the average growth of age- and sex-matched controls from a database of three-dimensional facial photographs of clinically normal subjects. After surgical removal of the fibrous cord, CMCC patients experience growth in the chin at the same rate as in the normal population; no evidence was found for catch-up growth. As a result, individuals with CMCC are likely to require further surgical intervention to correct the residual retrognathia on completion of facial growth. Early excision of the lesion including aggressive resection of the fibrous band is still recommended, as this should optimize the early growth of the mandible in infancy.
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Región Branquial/anomalías , Anomalías Craneofaciales/cirugía , Desarrollo Maxilofacial , Cuello/anomalías , Cuello/cirugía , Enfermedades Faríngeas/cirugía , Procedimientos de Cirugía Plástica/métodos , Región Branquial/diagnóstico por imagen , Región Branquial/cirugía , Niño , Preescolar , Anomalías Craneofaciales/diagnóstico por imagen , Femenino , Humanos , Imagenología Tridimensional , Lactante , Masculino , Enfermedades Faríngeas/diagnóstico por imagen , Resultado del TratamientoRESUMEN
Developmental defects in dental enamel pose significant clinical challenges which have highlighted our limited understanding of the structure and properties of this tissue. In this study, we first investigated the contact-size dependence of the physical properties of sound and hypomineralized enamel, and then examined the microstructure to establish a structural basis for their differing properties. Depth-sensing indentation tests were carried out over a wide range of peak loads in a direction perpendicular to the enamel prisms. Hypomineralized enamel demonstrated stronger penetration dependence for measured hardness and elastic modulus than sound enamel. The microstructure of sound and hypomineralized enamel was observed using field emission scanning electron microscopy and transmission electron microscopy with support of a focused ion beam milling system. Images of sound enamel showed barely distinguishable sheath regions with minimal organic presence. In contrast, hypomineralized enamel showed thicker sheath structures surrounding the prisms and higher levels of organic content within both the prisms and the sheath regions. It is argued that the higher organic content within prism structure was responsible for an initial lower hardness and elastic modulus of hypomineralized enamel under low-load indentation. As the indentation depth increased, the thicker organic-rich sheath regions played a more important role in reducing the mechanical properties of the hypomineralized enamel. On the basis of Spears finite element model [Spears IR. A three-dimensional finite element model of prismatic enamel: a re-appraisal of the data on the Young's modulus of enamel. J Dental Res 1997; 76(10):1690-97], elastic moduli of sound and hypomineralized enamel were predicted, which matched experimental results.
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Esmalte Dental/química , Esmalte Dental/ultraestructura , Minerales/química , Humanos , Microscopía Electrónica de Rastreo , Microscopía Electrónica de TransmisiónRESUMEN
Secondary alveolar bone grafting is a key procedure in comprehensive cleft services, the main objective of which is to allow the canine to erupt through the bone. We have assessed the outcomes of the procedure at two units, one in Australia and one in the UK. Success was measured using standardised indexes for radiological assessment (Bergland and Kindelan) and clinically by noting eruption of canines through the grafted sites. The two-year review indicated that the two units had comparably high success rates. Canines erupted through cleft sites in 27/28 sites in patients in the UK, and 26/28 in patients in Australia, and the radiological success using the indexes was also high. These rates are in line with international benchmarks.
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Injerto de Hueso Alveolar/métodos , Labio Leporino/cirugía , Fisura del Paladar/cirugía , Adolescente , Australia , Benchmarking , Niño , Labio Leporino/diagnóstico por imagen , Fisura del Paladar/diagnóstico por imagen , Estudios Transversales , Femenino , Humanos , Masculino , Reoperación , Estudios Retrospectivos , Erupción Dental , Resultado del Tratamiento , Reino UnidoRESUMEN
OBJECTIVE: To explore the oral health beliefs and practices of primary health care professionals which may act as barriers to the development of a model of shared care for the oral health of pre-school children. DESIGN: Qualitative focus group discussions and semi-structured interviews. SETTING: Four rural local government areas in Victoria, Australia, 2003. SUBJECTS: maternal and child health nurses, general medical practitioners, dental professionals and paediatricians working in the four local government areas. DATA COLLECTION: discipline specific focus groups and semi-structured interviews. DATA ANALYSIS: transcription, coding, clustering and thematic analysis. RESULTS: Several strong themes emerged from the data. All participants agreed that dental caries is a significant health issue for young children and their families. Beliefs about the aetiology of dental caries and its prevention were variable and often simplistic focusing predominantly on diet. Dental professionals did not believe that they had a primary role in the oral health of pre-school aged children but that others particularly maternal and child health nurses did. However other health care professionals were not confident in assuming this role. CONCLUSIONS: This study has identified important barriers and possible strategies for the development of an integrated and shared approach to preventing dental caries in pre-school aged children. Clear and consistent oral health information and agreed roles and responsibilities need to be developed.
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Actitud del Personal de Salud , Prestación Integrada de Atención de Salud , Atención Dental para Niños , Caries Dental/prevención & control , Preescolar , Conducta Cooperativa , Grupos Focales , Educación en Salud Dental , Conocimientos, Actitudes y Práctica en Salud , Humanos , Entrevistas como Asunto , Modelos Organizacionales , Investigación Cualitativa , Población Rural , Victoria , Poblaciones Vulnerables , Recursos HumanosRESUMEN
Isolated enamel defects are commonly seen in first permanent molar teeth but there has been little work on the physical and morphological composition of affected molars. The aim of this study was to determine the mechanical and morphological properties of hypomineralised first permanent molar teeth, utilising the Ultra-Micro-Indentation System (UMIS) and scanning electron microscope, respectively. Further investigations using Energy Dispersive X-ray Spectrometery (EDS), Back Scatter Electron (BSE) Imaging, and X-ray diffraction were employed to attempt to determine the chemical composition, mineral content and crystalline structure of the hypomineralised tissue, respectively, of eight first permanent molars with severe enamel hypomineralisation. The hardness and modulus of elasticity were found to be statistically significantly lower (0.53+/-0.31 and 14.49+/-7.56 GPa, respectively) than normal enamel (3.66+/-0.75 and 75.57+/-9.98 GPa, respectively). Although the fractured surface of the hypomineralised enamel was significantly more disorganised and the relative mineral content was reduced by approximately 5% in comparison to sound enamel, the mineral phase and Ca/P ratio was similar in hypomineralised and sound enamel. The dramatic reduction in the mechanical properties of first permanent molar teeth has ramifications when clinicians are choosing restorative materials to restore the defects. The reason for the dramatic reduction in mechanical properties of hypomineralised first permanent molar teeth is at present unknown.
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Esmalte Dental/ultraestructura , Dentición Permanente , Diente/ultraestructura , Absorciometría de Fotón , Esmalte Dental/química , Hipoplasia del Esmalte Dental , Dentina , Electrones , Humanos , Procesamiento de Imagen Asistido por Computador , Microscopía Electrónica de Rastreo , Diente Molar/química , Dispersión de Radiación , Estrés Mecánico , Temperatura , Resistencia a la Tracción , Calcificación de Dientes , Difracción de Rayos XRESUMEN
BACKGROUND: Gingival overgrowth is a recognized side effect of cyclosporine therapy with cosmetic and functional sequelae. This study examines the incidence and severity of gingival overgrowth in pediatric heart and heart-lung transplant recipients. METHODS: Thirty-one pediatric heart and heart-lung transplant recipients underwent a comprehensive dental evaluation. The severity of gingival overgrowth was scored by use of dental plaster casts. Parameters of dental hygiene in each patient included both a plaque index and a gingival inflammation index. The mean cyclosporine level and daily dose (mg/kg/day) at 3 and 12 months after transplantation and at latest follow-up were determined. RESULTS: The mean (+/- SD) patient age at transplantation was 10.5 (+/- 5.5) years, and the mean duration of posttransplantation follow-up was 3.2 (+/- 2.1) years. In all 30/31 (97%) of the cohort had some degree of overgrowth, with children aged less than 10 years at time of transplantation the most severely affected. By univariate analysis gingival overgrowth was inversely related to age at time of transplantation (r = -0.67, p < 0.001). With multiple regression analysis, only age at transplantation was significantly related to gingival overgrowth. CONCLUSIONS: Gingival overgrowth occurs in most pediatric heart and heart-lung transplant recipients treated with cyclosporine and is most severe in the younger patients. Attention to oral hygiene may improve gingival health parameters; however, the daily weight-adjusted dose of cyclosporine is not related to the severity of overgrowth.
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Ciclosporina/efectos adversos , Sobrecrecimiento Gingival/inducido químicamente , Trasplante de Corazón , Trasplante de Corazón-Pulmón , Inmunosupresores/efectos adversos , Factores de Edad , Análisis de Varianza , Peso Corporal , Niño , Preescolar , Estudios de Cohortes , Ciclosporina/administración & dosificación , Ciclosporina/sangre , Índice de Placa Dental , Estética Dental , Femenino , Estudios de Seguimiento , Sobrecrecimiento Gingival/clasificación , Gingivitis/inducido químicamente , Humanos , Inmunosupresores/administración & dosificación , Inmunosupresores/sangre , Incidencia , Masculino , Modelos Dentales , Higiene Bucal , Índice Periodontal , Análisis de RegresiónRESUMEN
Techniques used to restore carious primary molars have changed over the past decade as new adhesive materials have been developed. The most meaningful way of assessing the efficacy of a technique is by clinical trials. This article reviews the information concerning amalgam, composite and glass polyalkenoate (ionomer) cement as well as extracoronal restorations. Stainless steel/nickel chrome crowns provide the most durable restoration, often surviving until the tooth exfoliates. Class II amalgam restorations, whilst being prone to fracture, have been shown to survive about 3 years, a figure that improves with increasing age of the child and the use of local anaesthesia. Over the shorter term resin-based composites appear to be at least as durable as amalgam, particularly with respect to the maintenance of a good anatomical form. In contrast, when assessed at 6 years the failure rate of composite restorations is high, 62%, whereas the failure rate of amalgam restorations at 5 years is as low as 20%. Glass ionomer cements and cermets are alternative materials for use in the primary dentition. The reported success rate of 33% over 5 years for conventional glass ionomer cements is encouraging, however cermets appear to be less successful but have not been evaluated over the longer term. Glass ionomer cements provide a means of restoring primary molars with minimal amount of destruction of sound tooth tissue and reduced treatment time for the young patient, whilst the local fluoride release is also a potential advantage.(ABSTRACT TRUNCATED AT 250 WORDS)
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Materiales Dentales/química , Restauración Dental Permanente , Diente Molar , Diente Primario , Humanos , Propiedades de SuperficieRESUMEN
OBJECTIVE: Baseline information on the mechanical properties of and the effect of load upon dental hard tissue is important in the development of successful dental materials. Existing methods of measuring such properties of tissue are subject to significant experimental error. This study reports on the use of an Ultra-Micro-Indentation System (UMIS) to measure the hardness and elastic modulus of primary enamel and dentine. METHODS: Primary molar teeth were sectioned, set in resin and polished. Thirty indentations were made in enamel and dentine using a Berkovitch indentor, 15 of which were subject to a load of 50mN and 15 to a load of 150mN. An automated computerised system converted the force/penetration graph for each indentation in to a hardness vs depth graph from which values for the mean hardness and elastic modulus were calculated. RESULTS: Primary enamel had a mean hardness of 4.88+/-0.35GPa whilst the hardness of dentine was 0.92+/-0.11GPa The elastic modulus for enamel was 80.35+/-7.71GPa and that of dentine 19.89+/-1.92GPa. Using linear regression analysis a significant relationship could be shown between the hardness and the elastic modulus for both enamel and dentine when loaded to 150mN but only for dentine at 50mN (P<0.05). In general the elasticity of tooth structure increased as the hardness increased. CONCLUSION: The UMIS offers a simple and reproducible method of measuring basic mechanical properties of small samples of enamel and dentine.
Asunto(s)
Pruebas de Dureza , Diente Molar/química , Diente Primario/química , Preescolar , Esmalte Dental/química , Análisis del Estrés Dental/instrumentación , Análisis del Estrés Dental/métodos , Dentina/química , Elasticidad , Dureza , Humanos , Modelos Lineales , Reproducibilidad de los Resultados , Procesamiento de Señales Asistido por ComputadorRESUMEN
OBJECTIVE: The fracture of bonded ceramic to metal restorations remains a problem in clinical dental practice. The use of resin based composites to repair such fractures is generally unsatisfactory. Tribochemical technology creates a surface layer of small silica particles fused to the surface substrate. Such a layer potentially improves adhesion of resin to both alloy and porcelain. Adhesion between two substrates is traditionally studied using shear or tensile bond strength tests. However, the highest stress at bond failure may not represent the real bonding characteristics correctly. An alternative method is to describe the bonding characteristics by determining the strain energy release rate for a given interface. This study compares the bonding characteristics of a resin to gold/porcelain interface using a tribochemical coating process with those of a control group using simple gritblasting. METHODS: Pre-cracked specimens were subjected to load-unload cycles using a simple four point bending test and the resultant strain energy release rates were calculated. RESULTS: Tribochemically pretreating the porcelain resulted in a significant increase in the resultant strain energy release rate from 42.72+/-3.65J/m(2) for the controls to 61.35+/-6.26J/m(2). Likewise there was a significant improvement in the strain energy release rate for the gold/composite interface from 27.31+/-3.00J/m(2) to 42.13+/-4.83J/m(2). CONCLUSIONS: Tribochemical technology offers significant potential advantages for clinical dental practice.