Detalles de la búsqueda
1.
Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function.
Hum Mol Genet;
32(19): 2857-2871, 2023 09 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-37369021
2.
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor.
Cell Mol Life Sci;
81(1): 153, 2024 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38538865
3.
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions.
Cell Mol Life Sci;
80(2): 42, 2023 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36645496
4.
Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening.
Cell Mol Life Sci;
80(4): 110, 2023 Mar 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37000222
5.
Overlapping cortical malformations in patients with pathogenic variants in GRIN1 and GRIN2B.
J Med Genet;
60(2): 183-192, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35393335
6.
Opportunities for Precision Treatment of GRIN2A and GRIN2B Gain-of-Function Variants in Triheteromeric N-Methyl-D-Aspartate Receptors.
J Pharmacol Exp Ther;
381(1): 54-66, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35110392
7.
Compound-heterozygous GRIN2A null variants associated with severe developmental and epileptic encephalopathy.
Epilepsia;
63(10): e132-e137, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35983985
8.
Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.
Proc Natl Acad Sci U S A;
116(11): 5160-5169, 2019 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30796190
9.
Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice.
Brain;
143(7): 2039-2057, 2020 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32577763
10.
Murine breast cancer feed arteries are thin-walled with reduced α1A-adrenoceptor expression and attenuated sympathetic vasocontraction.
Breast Cancer Res;
20(1): 20, 2018 03 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-29566737
11.
Na-K-ATPase regulates intercellular communication in the vascular wall via cSrc kinase-dependent connexin43 phosphorylation.
Am J Physiol Cell Physiol;
312(4): C385-C397, 2017 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28122732
12.
Perivascular tissue inhibits rho-kinase-dependent smooth muscle Ca(2+) sensitivity and endothelium-dependent H2 S signalling in rat coronary arteries.
J Physiol;
593(21): 4747-64, 2015 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26350036
13.
Voltage-gated sodium channels contribute to action potentials and spontaneous contractility in isolated human lymphatic vessels.
J Physiol;
593(14): 3109-22, 2015 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25969124
14.
Human lymphatic vessel contractile activity is inhibited in vitro but not in vivo by the calcium channel blocker nifedipine.
J Physiol;
592(21): 4697-714, 2014 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25172950
15.
The contribution of K(+) channels to human thoracic duct contractility.
Am J Physiol Heart Circ Physiol;
307(1): H33-43, 2014 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24778167
16.
Distances from ligands as main predictive features for pathogenicity and functional effect of variants in NMDA receptors.
medRxiv;
2024 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38766179
17.
Endothelial alkalinisation inhibits gap junction communication and endothelium-derived hyperpolarisations in mouse mesenteric arteries.
J Physiol;
591(6): 1447-61, 2013 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23297309
18.
Intrathecal magnesium delivery for Mg++-insensitive NMDA receptor activity due to GRIN1 mutation.
Orphanet J Rare Dis;
18(1): 225, 2023 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37537625
19.
Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor.
ACS Chem Neurosci;
14(17): 3059-3076, 2023 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37566734
20.
Positive chronotropic action of HCN channel antagonism in human collecting lymphatic vessels.
Physiol Rep;
10(16): e15401, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35980021