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1.
J Ren Nutr ; 33(6S): S13-S20, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-37343779

RESUMEN

Phosphorus is a vital nutrient, but disturbances in phosphorus homeostasis are central to chronic kidney disease-mineral and bone disorder. To minimize disturbances, traditional dietary guidance focused on a numerical phosphorus target leading to the exclusion of many healthy foods and implementation challenges. Contemporary phosphorus guidance focuses on dietary source, avoiding additives, and emphasizing low-phosphorus bioaccessibility foods, leading to a more liberal approach. Additional work is needed to demonstrate the efficacy of these contemporary approaches and understand the influence of specific foods, processing, and cooking methods. Unfortunately, patient education using traditional and contemporary strategies may give mixed messages, particularly related to plant-based foods. Thus, greater clarity on the effects of specific foods and dietary patterns may improve phosphorus education. This review aims to discuss the evolution of dietary phosphorus management while highlighting areas for future research that can help move the field toward stronger evidence-based guidance to prevent and treat hyperphosphatemia.


Asunto(s)
Hiperfosfatemia , Fósforo Dietético , Insuficiencia Renal Crónica , Humanos , Fósforo , Insuficiencia Renal Crónica/terapia , Hiperfosfatemia/prevención & control , Dieta
2.
J Ren Nutr ; 33(6S): S6-S12, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-37610407

RESUMEN

Potassium disorders are one of the most common electrolyte abnormalities in patients with chronic kidney disease (CKD), contributing to poor clinical outcomes. Maintaining serum potassium levels within the physiologically normal range is critically important in these patients. Dietary potassium restriction has long been considered a core strategy for the management of chronic hyperkalemia in patients with CKD. However, this has been challenged by recent evidence suggesting a paradigm shift toward fostering more liberalized, plant-based dietary patterns. The advent of novel potassium binders and an improved understanding of gastrointestinal processes involved in potassium homeostasis (e.g., gastrointestinal potassium wasting) may facilitate a paradigm shift and incorporation of heart-healthy potassium-enriched food sources. Nevertheless, uncertainty regarding the risk-benefit of plant-based diets in the context of potassium management in CKD remains, requiring well-designed clinical trials to determine the efficacy of dietary potassium manipulation toward improvement of clinical outcomes in patients with CKD.


Asunto(s)
Hiperpotasemia , Insuficiencia Renal Crónica , Humanos , Potasio , Potasio en la Dieta/efectos adversos , Insuficiencia Renal Crónica/complicaciones , Dieta
3.
J Ren Nutr ; 32(2): 224-233, 2022 03.
Artículo en Inglés | MEDLINE | ID: mdl-33888409

RESUMEN

OBJECTIVE: Protein-energy wasting is highly prevalent in people with end-stage kidney disease receiving regular hemodialysis. Currently, it is unclear what the optimal nutritional recommendations are, which is further complicated by differences in dietary patterns between countries. The aim of the study was to understand and compare dietary intake between individuals receiving hemodialysis in Leicester, UK and Nantong, China. METHODS: The study assessed 40 UK and 44 Chinese participants' dietary intake over a period of 14 days using 24-hour diet recall interviews. Nutritional blood parameters were obtained from medical records. Food consumed by participants in the UK and China was analyzed using the Nutritics and Nutrition calculator to quantify nutritional intake. RESULTS: Energy and protein intake were comparable between UK and Chinese participants, but with both below the recommended daily intake. Potassium intake was higher in UK participants compared to Chinese participants (2,115 [888] versus 1,159 [861] mg/d; P < .001), as was calcium (618 [257] versus 360 [312] mg/d; P < .001) and phosphate intake (927 [485] versus 697 [434] mg/d; P = .007). Vitamin C intake was lower in UK participants compared to their Chinese counterparts (39 [51] versus 64 [42] mg/d; P = .024). Data are reported here as median (interquartile range). CONCLUSION: Both UK and Chinese hemodialysis participants have insufficient protein and energy in their diet. New strategies are required to increase protein and energy intakes. All participants had inadequate daily intake of vitamins C and D; there may well be a role in the oral supplementation of these vitamins, and further studies are urgently needed.


Asunto(s)
Ingestión de Alimentos , Ingestión de Energía , Humanos , Encuestas Nutricionales , Diálisis Renal , Vitaminas
4.
J Am Psychiatr Nurses Assoc ; 28(3): 235-240, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-33150807

RESUMEN

OBJECTIVES: People with chronic kidney disease (CKD) are at increased risk for falls and fall-related injuries. Depressive disorders (DEP) are common in individuals with CKD and may increase the risk of falls and fall-related injuries. However, not much is known about the relationship between DEP and falls in people with CKD. The purpose of this study was to determine the influence of DEP on the relationship between CKD, falls, and fall-related injuries. METHOD: Using the Behavioral Risk Factor Surveillance System, we identified 16,574 adults with CKD. Patients with CKD were stratified by history of self-reported DEP (SRDEP), and multivariate logistic regression was conducted to determine the odds for falls and fall-related injuries among those with and without SRDEP. RESULTS: In unadjusted regression analysis, falls (OR = 2.40, 95% CI = 2.08-2.76) and fall-related injuries (OR = 2.12, 95% CI = 1.72-2.59) were higher in individuals with CKD and history of SRDEP compared to those with CKD and no history of SRDEP. Adjustment for confounders had little effect on the relationship between a history of SRDEP and either falls (AOR = 1.87, 95% CI = 1.60-2.19) or fall-related injuries (AOR = 1.58, 95% CI = 1.26-1.97). CONCLUSIONS: People with CKD and DEP are at increased odds for falls and fall-related injuries even after adjustment for sociodemographic, lifestyle factors, and comorbidities. Prospective studies are warranted to further understand this relationship, but it may be prudent for clinicians, in particular nurses, to consider fall risk when treating DEP in patients with CKD.


Asunto(s)
Trastorno Depresivo , Insuficiencia Renal Crónica , Accidentes por Caídas , Adulto , Comorbilidad , Trastorno Depresivo/complicaciones , Trastorno Depresivo/epidemiología , Femenino , Humanos , Masculino , Estudios Prospectivos , Insuficiencia Renal Crónica/complicaciones , Insuficiencia Renal Crónica/epidemiología , Factores de Riesgo
5.
Semin Dial ; 2021 Oct 27.
Artículo en Inglés | MEDLINE | ID: mdl-34708456

RESUMEN

Chronic kidney disease (CKD) affects 9.1% of the population worldwide. CKD may lead to structural and functional gastrointestinal alterations, including impairment in the intestinal barrier, digestion and absorption of nutrients, motility, and changes to the gut microbiome. These changes can lead to increased gastrointestinal symptoms in people with CKD, even in early grades of kidney dysfunction. Gastrointestinal symptoms have been associated with lower quality of life and reduced nutritional status. Therefore, there has been considerable interest in improving gastrointestinal health in this clinical population. Gastrointestinal health can be influenced by lifestyle and medications, particularly in advanced grades of kidney dysfunction. Therapies focused on gastrointestinal health have been studied, including the use of probiotics, prebiotics, and synbiotics, yielding limited and conflicting results. This review summarizes the alterations in the gastrointestinal tract structure and function and provides an overview of potential nutritional interventions that kidney disease professionals can provide to improve gastrointestinal health in individuals with CKD.

6.
J Ren Nutr ; 31(5): 512-522, 2021 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-34120835

RESUMEN

OBJECTIVE: The prebiotic fiber inulin has been studied in individuals undergoing hemodialysis (HD) due to its ability to reduce gut microbiota-derived uremic toxins. However, studies examining the effects of inulin on the gut microbiota and derived metabolites are limited in these patients. We aimed to assess the impact of a 4-week supplementation of inulin on the gut microbiota composition and microbial metabolites of patients on HD. DESIGN AND METHODS: In a randomized, double-blind, placebo-controlled, crossover study, twelve HD patients (55 ± 10 y, 50% male, 58% Black American, BMI 31.6 ± 8.9 kg/m2, 33% diabetes mellitus) were randomized to consume inulin [10 g/d for females; 15 g/d for males] or maltodextrin [6 g/d for females; 9 g/d for males] for 4 weeks, with a 4-week washout period. We assessed the fecal microbiota composition, fecal metabolites (short-chain fatty acids (SCFA), phenols, and indoles), and plasma indoxyl sulfate and p-cresyl sulfate. RESULTS: At baseline, factors that explained the gut microbiota variability included BMI category and type of phosphate binder prescribed. Inulin increased the relative abundance of the phylum Verrucomicrobia and its genus Akkermansia (P interaction = 0.045). Inulin and maltodextrin resulted in an increased relative abundance of the phylum Bacteroidetes and its genus Bacteroides (P time = 0.04 and 0.03, respectively). Both treatments increased the fecal acetate and propionate (P time = 0.032 and 0.027, respectively), and there was a trend toward increased fecal butyrate (P time = 0.06). Inulin did not reduce fecal p-cresol or indoles, or plasma concentrations of p-cresyl sulfate or indoxyl sulfate. CONCLUSIONS: A 4-week supplementation of inulin did not lead to major shifts in the fecal microbiota and gut microbiota-derived metabolites. This may be due to high variability among participants and an unexpected increase in fecal excretion of SCFA with maltodextrin. Larger studies are needed to determine the effects of prebiotic fibers on the gut microbiota and clinical outcomes to justify their use in patients on HD.


Asunto(s)
Microbioma Gastrointestinal , Inulina , Estudios Cruzados , Femenino , Humanos , Masculino , Proyectos Piloto , Prebióticos , Diálisis Renal , Tóxinas Urémicas
7.
J Ren Nutr ; 31(2): 116-120.e1, 2021 03.
Artículo en Inglés | MEDLINE | ID: mdl-32737016

RESUMEN

The Academy of Nutrition and Dietetics and the National Kidney Foundation collaborated to provide an update to the Clinical Practice Guidelines (CPG) for nutrition in chronic kidney disease (CKD). These guidelines provide a valuable update to many aspects of the nutrition care process. They include changes in the recommendations for nutrition screening and assessment, macronutrients, and targets for electrolytes and minerals. The International Society of Renal Nutrition and Metabolism assembled a special review panel of experts and evaluated these recommendations prior to public review. As one of the highlights of the CPG, the recommended dietary protein intake range for patients with diabetic kidney disease is 0.6-0.8 g/kg/day, whereas for CKD patients without diabetes it is 0.55-0.6 g/kg/day. The International Society of Renal Nutrition and Metabolism endorses the CPG with the suggestion that clinicians may consider a more streamlined target of 0.6-0.8 g/kg/day, regardless of CKD etiology, while striving to achieve intakes closer to 0.6 g/kg/day. For implementation of these guidelines, it will be important that all stakeholders work to detect kidney disease early to ensure effective primary and secondary prevention. Once identified, patients should be referred to registered dietitians or the region-specific equivalent, for individualized medical nutrition therapy to slow the progression of CKD. As we turn our attention to the new CPG, we as the renal nutrition community should come together to strengthen the evidence base by standardizing outcomes, increasing collaboration, and funding well-designed observational studies and randomized controlled trials with nutritional and dietary interventions in patients with CKD.


Asunto(s)
Dietética , Nutricionistas , Insuficiencia Renal Crónica , Proteínas en la Dieta , Humanos , Riñón , Insuficiencia Renal Crónica/complicaciones , Insuficiencia Renal Crónica/terapia
8.
J Ren Nutr ; 28(2): 129-134, 2018 03.
Artículo en Inglés | MEDLINE | ID: mdl-29471989

RESUMEN

OBJECTIVE: Intradialytic nutrition has been shown to improve nutritional status in maintenance hemodialysis (HD) patients but remains controversial due in part to concerns over hemodynamic stability and gastrointestinal (GI) distress. There are limited data on the relationship between intradialytic nutrition and GI symptoms, possibly due to the lack of a validated tool. Therefore, we intended to validate a questionnaire to measure GI symptoms associated with a single HD treatment and determine the relationship between intradialytic nutrition and GI symptoms. DESIGN: Cross-sectional study. Forty-eight maintenance HD patients. MAIN OUTCOME MEASURE: GI symptoms and dietary intake during HD treatment. RESULTS: In general, we found acceptable internal consistency (Cronbach's alpha >0.5, exception reflux domain) and repeatability in all 5 domains of a modified version of the Gastrointestinal Symptom Rating Scale. The prevalence of GI symptoms associated with a single HD treatment (generalized score greater than 1) was 54.2, 43.7, 6.2, 41.7, and 45.8% for the abdominal pain, indigestion, reflux, diarrhea, and constipation domains, respectively. More than two-thirds of patients chose to eat during treatment (168.6 ± 165.6 kcal) with the most commonly consumed items being candy, oral supplements, and cookies. There was no difference in GI symptoms among patients who did or did not eat (P > .05). However, the amount of total dietary fat and fiber consumed during treatment was associated with greater indigestion (P < .05) prior to accounting for outliers or multiple comparisons. CONCLUSION: In this sample, the modified version of the Gastrointestinal Symptom Rating Scale was a generally valid tool for measuring GI symptoms associated with a single HD treatment. Patients who ate during treatment did not experience greater GI symptoms than those who did not; however, high amounts of fat and fiber may be associated with greater GI symptoms. Prospective trials should examine the relationship between GI symptoms and dietary intake during treatment in HD patients.


Asunto(s)
Dieta , Enfermedades Gastrointestinales/epidemiología , Estado Nutricional , Diálisis Renal/efectos adversos , Dolor Abdominal/epidemiología , Adulto , Anciano , Estreñimiento/epidemiología , Estudios Transversales , Diarrea/epidemiología , Grasas de la Dieta/administración & dosificación , Fibras de la Dieta/administración & dosificación , Dispepsia/epidemiología , Femenino , Reflujo Gastroesofágico/epidemiología , Humanos , Fallo Renal Crónico/terapia , Masculino , Persona de Mediana Edad , Reproducibilidad de los Resultados
10.
J Ren Nutr ; 28(1): 4-12, 2018 01.
Artículo en Inglés | MEDLINE | ID: mdl-29249295

RESUMEN

Poor nutritional status and protein-energy wasting are common among maintenance dialysis patients and associated with unfavorable outcomes. Providing foods, meal trays, snack boxes, and/or oral nutritional supplements during hemodialysis can improve nutritional status and might also reduce inflammation, enhance health-related quality of life, boost patient satisfaction, and improve survival. Potential challenges include postprandial hypotension and other hemodynamic instabilities, aspiration risk, gastrointestinal symptoms, hygiene issues, staff burden, reduced solute removal, and increased costs. Differing in-center nutrition policies exist within organizations and countries around the world. Recent studies have demonstrated clinical benefits and highlight the need to work toward clear guidelines. Meals or supplements during hemodialysis may be an effective strategy to improve nutritional status with limited reports of complications in real-world scenarios. Whereas larger multicenter randomized trials are needed, meals and supplements during hemodialysis should be considered as a part of the standard-of-care practice for patients without contraindications.


Asunto(s)
Ingestión de Alimentos , Riñón/metabolismo , Desnutrición Proteico-Calórica/prevención & control , Diálisis Renal/efectos adversos , Insuficiencia Renal Crónica/terapia , Sociedades Científicas , Biomarcadores/sangre , Dieta , Suplementos Dietéticos , Humanos , Comidas , Estado Nutricional , Estudios Observacionales como Asunto , Desnutrición Proteico-Calórica/etiología , Calidad de Vida , Insuficiencia Renal Crónica/complicaciones
11.
Prev Chronic Dis ; 15: E82, 2018 06 21.
Artículo en Inglés | MEDLINE | ID: mdl-29935079

RESUMEN

INTRODUCTION: Falls are among the leading causes of injury and death among adults aged 65 or older. People with chronic kidney disease (CKD) are at increased risk of falling and of having a serious injury from falls. However, information is limited about risk factors for falls and fall-related injuries among people with CKD. METHODS: We performed a secondary analysis of 157,753 adults (6.1% with CKD) aged 65 or older surveyed in the 2014 Behavioral Risk Factor Surveillance System. RESULTS: People with CKD were at increased risk of falls (odds ratio [OR] = 1.81; 95% confidence interval [CI], 1.63-2.01) and fall-related injuries (OR = 1.50; 95% CI, 1.27-1.78) even after adjusting for differences in demographic characteristics, health conditions, and lifestyle factors (P < .05 for all). Among people with CKD, women, people diagnosed with diabetes, diabetes duration, and arthritis were all significant predictors of falls and fall-related injuries (P < .05 for all). Lifestyle factors, such as engaging in recent exercise (adjusted odds ratio [AOR] = 0.68; 95% CI, 0.56-0.81) and limited physical function (assessed as difficulty in climbing stairs) (AOR = 2.84; 95% CI, 2.30-3.44), were most closely associated with falls and fall-related injuries. CONCLUSION: Adults aged 65 or older with CKD were at increased risk of falling and of suffering an injury as a result of a fall compared with adults in the same age range without CKD. Potentially modifiable factors such as physical function and recent exercise were most closely related to reduced risk for falls and fall-related injuries and may be an appropriate target for fall prevention and rehabilitation programs in people with CKD.


Asunto(s)
Accidentes por Caídas/estadística & datos numéricos , Insuficiencia Renal Crónica , Anciano , Sistema de Vigilancia de Factor de Riesgo Conductual , Femenino , Humanos , Masculino , Oportunidad Relativa , Factores de Riesgo
13.
J Ren Nutr ; 25(2): 81-7, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-25443693

RESUMEN

The annual mortality rate for patients undergoing maintenance hemodialysis (MHD) treatment in the United States is 20%, a rate higher than most other countries in the world. Poor nutrition status in MHD patients contributes to this adverse outcome as well as poor quality of life. Providing oral nutrition to MHD patients, especially during hemodialysis (HD) treatment has many potential benefits including improvements in nutrition status and attenuating HD-related muscle wasting. However, this practice is generally restricted in the United States presumably because of concerns that include worsening hemodynamic instability, reductions in treatment efficiency, and increased gastrointestinal symptoms. Despite widespread restrictions, few studies have adequately examined the effect of eating during HD on these outcomes, leaving many questions unanswered. This review outlines the current evidence regarding the effects of feeding during HD and provides potential future directions to outline the best practices in this controversial area.


Asunto(s)
Ingestión de Alimentos , Fallo Renal Crónico/terapia , Estado Nutricional , Diálisis Renal , Humanos , Guías de Práctica Clínica como Asunto , Estados Unidos
14.
J Ren Nutr ; 25(3): 276-83, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25455421

RESUMEN

OBJECTIVE: Protein malnutrition is both a cause and consequence of inflammation and related comorbidities for maintenance hemodialysis (MHD) patients. This study sought to determine if oral supplementation with soy or whey protein during dialysis treatment reduces inflammation and improves physical function and body composition in MHD patients. DESIGN: The design used in the study was randomized controlled trial, and the setting used was hemodialysis clinics in Champaign and Chicago, Illinois. SUBJECTS: Patients who received treatment ≥3 days/week, were ages ≥30 years did not have congestive heart failure or chronic obstructive pulmonary disease, and were receiving dialysis treatment for ≥3 months were eligible for inclusion. INTERVENTION: Patients were randomized to oral supplementation with a whey protein, soy protein, or placebo beverage. Patients (WHEY, n = 11; SOY, n = 12; CON, n = 15) consumed their assigned beverage before every dialysis session for 6 months. MAIN OUTCOME MEASURES: Body composition was measured by dual-energy x-ray absorptiometry, physical function by gait speed and shuttle walk test, and markers of inflammation (C-reactive protein and interleukin 6) using commercially available enzyme-linked immunosorbent assay kits before and after the 6-month intervention. Dietary intake was assessed by 24-hour dietary recalls. RESULTS: Six months of whey or soy supplementation significantly reduced predialysis interleukin 6 levels (P < .05 for both), whereas there was a trend for a reduction in C-reactive protein when both protein groups were combined (P = .062). Gait speed and shuttle walk test performance also significantly improved in the protein groups (P < .05 for both). No changes in body composition were observed. However, alkaline phosphatase, a marker of bone turnover, was significantly reduced in the protein groups. CONCLUSIONS: Intradialytic protein supplementation during a 6-month intervention reduced inflammation and improved physical function and represents an affordable intervention to improve the health of MHD patients.


Asunto(s)
Proteínas en la Dieta/administración & dosificación , Inflamación/prevención & control , Diálisis Renal , Adulto , Bebidas , Composición Corporal , Proteína C-Reactiva/análisis , Suplementos Dietéticos , Femenino , Marcha , Humanos , Interleucina-6/sangre , Fallo Renal Crónico/terapia , Masculino , Persona de Mediana Edad , Aptitud Física , Placebos , Proteínas de Soja/administración & dosificación , Caminata/fisiología , Proteína de Suero de Leche/administración & dosificación
15.
Int J Sport Nutr Exerc Metab ; 24(6): 694-700, 2014 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-24901578

RESUMEN

The purpose of this study was to document the physiological changes that occur in a natural bodybuilder during prolonged contest preparation for a proqualifying contest. During the 26-week preparation, the athlete undertook a calorically restrictive diet with 2 days of elevated carbohydrate intake per week, increased cardiovascular (CV) training, and attempted to maintain resistance-training load. The athlete was weighed twice a week and body composition was measured monthly by DXA. At baseline and every 2 weeks following CV structure and function was measured using a combination of ultrasound, applanation tonometry, and heart rate variability (HRV). Cardiorespiratory performance was measured by VO(2)peak at baseline, 13 weeks, and 26 weeks. Body weight (88.6 to 73.3 Kg, R(2) = .99) and percent body fat (17.5 to 7.4%) were reduced during preparation. CV measurements including blood pressure (128/61 to 113/54 mmHg), brachial pulse wave velocity (7.9 to 5.8m/s), and measures of wave reflection all improved. Indexed cardiac output was reduced (2.5 to 1.8L/m(2)) primarily due to a reduction in resting heart rate (71 to 44 bpm), and despite an increase in ejection faction (57.9 to 63.9%). Assessment of HRV found a shift in the ratio of low to high frequency (209.2 to 30.9%). Absolute VO2 was minimally reduced despite weight loss resulting in an increase in relative VO2 (41.9 to 47.7 ml/Kg). In general, this prolonged contest preparation technique helped the athlete to improve body composition and resulted in positive CV changes, suggesting that this method of contest preparation appears to be effective in natural male bodybuilders.


Asunto(s)
Composición Corporal/fisiología , Entrenamiento de Fuerza/métodos , Levantamiento de Peso/fisiología , Adaptación Fisiológica , Adulto , Restricción Calórica , Dieta , Frecuencia Cardíaca/fisiología , Humanos , Masculino
16.
Nutrients ; 16(5)2024 Feb 20.
Artículo en Inglés | MEDLINE | ID: mdl-38474703

RESUMEN

Chronic kidney disease (CKD) disproportionately affects minorities in the United States, including the Hispanic/Latine population, and is a public health concern in Latin American countries. An emphasis on healthy dietary patterns, including the Mediterranean and the Dietary Approaches to Stop Hypertension (DASH) diets, has been suggested as they are associated with a lower incidence of CKD, slower CKD progression, and lower mortality in kidney failure. However, their applicability may be limited in people from Latin America. The Dieta de la Milpa (Diet of the Cornfield) was recently described as the dietary pattern of choice for people from Mesoamerica (Central Mexico and Central America). This dietary pattern highlights the intake of four plant-based staple foods from this geographical region, corn/maize, common beans, pumpkins/squashes, and chilies, complemented with seasonal and local intake of plant-based foods and a lower intake of animal-based foods, collectively classified into ten food groups. Limited preclinical and clinical studies suggest several health benefits, including cardiometabolic health, but there is currently no data concerning CKD. In this narrative review, we describe and highlight the potential benefits of the Dieta de la Milpa in CKD, including acid-base balance, protein source, potassium and phosphorus management, impact on the gut microbiota, inflammation, and cultural appropriateness. Despite these potential benefits, this dietary pattern has not been tested in people with CKD. Therefore, we suggest key research questions targeting measurement of adherence, feasibility, and effectiveness of the Dieta de la Milpa in people with CKD.


Asunto(s)
Enfoques Dietéticos para Detener la Hipertensión , Insuficiencia Renal Crónica , Humanos , Patrones Dietéticos , Insuficiencia Renal Crónica/complicaciones , Dieta , Hispánicos o Latinos
17.
Arch Phys Med Rehabil ; 94(1): 127-31, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-22858796

RESUMEN

OBJECTIVES: To investigate whether there is a reduction in walking with the simultaneous performance of a cognitive task (ie, dual-task cost [DTC]) in persons undergoing hemodialysis (HD), and whether it is greater in persons undergoing HD compared with age-matched controls. DESIGN: Cohort. SETTING: University research laboratory. PARTICIPANTS: Persons undergoing HD (n=14; 5 women, 9 men; mean age ± SD, 50.0±11.8y) and age-matched controls (n=14; 4 women, 10 men; mean age ± SD, 48.5±10.1y) participated in the investigation. INTERVENTIONS: Not applicable. MAIN OUTCOMES MEASURES: Participants walked at a self-selected pace on an electronic pathway, which recorded spatiotemporal parameters of gait, in 4 separate trials and completed a cognitive task in the last 2 trials. The DTC was quantified as the change in spatiotemporal parameters of gait from baseline to the cognitive trials. RESULTS: The HD group had a greater decrease in walking function during the cognitive task, with DTC ranging from 6% to 14%. On average, walking velocity decreased to less than 1m/s in HD patients during the cognitive condition. Baseline walking velocity was found to be moderately correlated with the magnitude of DTC of cadence and step time (ρ=-.44 and .46; P values <.05). CONCLUSIONS: Persons undergoing HD have greater interference between walking and talking compared with controls. Difficulty walking while thinking has implications for everyday life and may be related to the risk of falls. Further work is necessary to determine other contributing factors to elevated DTC in HD patients, and whether DTC can be reduced with targeted interventions.


Asunto(s)
Fallo Renal Crónico/terapia , Diálisis Renal , Habla/fisiología , Análisis y Desempeño de Tareas , Caminata/fisiología , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Persona de Mediana Edad
18.
J Appl Physiol (1985) ; 134(3): 508-514, 2023 03 01.
Artículo en Inglés | MEDLINE | ID: mdl-36656985

RESUMEN

Nutraceutical-based interventions hold promise to reduce blood pressure (BP) and arterial stiffness, which are two cardiovascular disease (CVD) risk factors. However, the effects of coconut sap powder (CSP), an Asian sweetener and novel nutraceutical, on BP and arterial stiffness in middle-aged and older adults (MA/O, ≥45 yr) has yet to be established. We hypothesized CSP will decrease BP and arterial stiffness in MA/O adults. In a double-blind, randomized, placebo-controlled study design, 19 (age 55.3 ± 2.1 yr) MA/O adults completed measures of brachial and carotid BP, and arterial stiffness [carotid-femoral pulse wave velocity (cfPWV), common carotid artery (CCA) ß-stiffness, compliance, distensibility, and Young's and Peterson's Elastic moduli] before and after 8 wk of CSP (1.5 g/day) or placebo (1.5 g/day). A two-way repeated-measures analysis of variance was used to compare group mean differences. Compared with placebo, CSP lowered brachial systolic BP (SBP) (CSP pre: 117.4 ± 2.9 vs. post: 109.0 ± 2.4 mmHg, P < 0.05), but not carotid SBP (P = 0.12). CSP also lowered Young's (CSP pre: 5,514.4 ± 1,115.4 vs. post: 3,690.6 ± 430.9 kPa) and Peterson's elastic moduli (CSP pre: 22.2 ± 4.4 vs. post: 19.2 ± 4.5 kPa) (P < 0.05, both). A trend for CSP to lower CCA ß-stiffness (P = 0.06) and increase CCA compliance (P = 0.07) was also observed. Arterial stiffness assessed by cfPWV did not change (P > 0.05). No inflammatory or antioxidant biomarkers were affected by CSP. In summary, 8 wk of CSP lowers brachial SBP and CCA mechanical stiffness indicating a potential cardioprotective effect in MA/O adults.NEW & NOTEWORTHY Blood pressure (BP) and arterial stiffness are important predictors of cardiovascular health with aging. Nutraceuticals are an easy-to-implement lifestyle strategy demonstrating promise to effectively lower BP and arterial stiffness with aging and ultimately cardiovascular disease risk. We demonstrate that coconut sap powder (CSP), a traditional Asian sweetener, lowers brachial systolic BP and carotid artery mechanical stiffness in middle-aged and older (MA/O) adults. These findings provide initial evidence for the CSP-related cardioprotective effects in MA/O adults.


Asunto(s)
Enfermedades Cardiovasculares , Rigidez Vascular , Persona de Mediana Edad , Humanos , Anciano , Presión Sanguínea/fisiología , Rigidez Vascular/fisiología , Cocos , Proyectos Piloto , Azúcares , Análisis de la Onda del Pulso , Inflorescencia , Polvos , Arterias Carótidas/fisiología , Edulcorantes
19.
J Hum Kinet ; 79: 111-122, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-34400991

RESUMEN

Hydration plays an important role in performance, injury prevention, and recovery for athletes engaged in competitive sports. Therefore, it is important that strength and conditioning coaches understand an athlete's hydration needs to prevent illness and enhance performance. The purpose of this study was to identify hydration knowledge, attitudes, and behaviors of collegiate track and field throwers, as well as identify barriers to hydration and sources of nutritional information. The Rehydration and Refueling in Collegiate Track and Field Throwers Survey was sent to 271 track and field thrower coaches with a request to forward the email to current track and field throwers. Pearson correlation coefficients were calculated regarding knowledge, attitude, and behavior scores among the participants in this sample. Differences among response patterns were assessed via Chi-square analysis. Alpha level was set at p = .05. Results demonstrated that 97.3% (n = 287) of respondents knew that dehydration would decrease performance, but 50.5% (n = 149) erroneously believed thirst was the best indicator of dehydration. Chi-square analysis demonstrated a significant difference in reported values between participants who intended to eat a performance-enhancing diet and those who consumed less fluid than recomended values (207 - 295 m)l in the 2-3 hours prior to competition (χ2 = 10.87, p < .05). Pearson correlation coefficients demonstrated a large association between knowledge and behavior (r = .70, p < .05), a medium association between knowledge and attitude (r = .41, p < .05), and a small association between attitude and behavior (r = .21, p < .05). This suggests that strength and conditioning coaches and health staff need to educate and monitor hydration behaviors among collegiate track and field throwers to optimize performance.

20.
J Strength Cond Res ; 24(9): 2280-4, 2010 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-20683355

RESUMEN

Previous research has shown that static stretching has an inhibitory effect on sprinting performances up to 50 m. The purpose of this study was to see what would happen to these effects at longer distances such as those seen in competition. This study used a within-subjects design to investigate the effects of passive static stretching vs. no stretching on the 60- and 100-m sprint performance of college track athletes after a dynamic warm-up. Eighteen male subjects completed both the static stretching and the no stretching conditions in counterbalanced order across 2 days of testing. On each day, all subjects first completed a generalized dynamic warm-up routine that included a self-paced 800-m run, followed by a series of dynamic movements, sprint, and hurdle drills. At the end of this generalized warm-up, athletes were assigned to either a static stretching or a no-stretching condition. They then immediately performed 2 100-m trials with timing gates set up at 20, 40, 60, and 100 m. Results revealed a significant slowing in performance with static stretching (p < 0.039) in the second 20 (20-40) m of the sprint trials. After the first 40 m, static stretching exhibited no additional inhibition of performance in a 100-m sprint. However, although there was no additional time loss, athletes never gained back the time that was originally lost in the first portion of the trials. Therefore, in strict terms of performance, it seems harmful to include static stretching in the warm-up protocol of collegiate male sprinters in distances up to 100 m.


Asunto(s)
Ejercicios de Estiramiento Muscular/métodos , Carrera/fisiología , Rendimiento Atlético/fisiología , Humanos , Masculino , Factores de Tiempo , Atletismo/fisiología , Adulto Joven
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