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1.
Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation.
Eur Respir J;
59(2)2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34737220
2.
Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study.
Am J Respir Crit Care Med;
203(1): 37-53, 2021 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32667261
3.
Exhaled volatile organic compounds as markers for medication use in asthma.
Eur Respir J;
55(2)2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31515400
4.
AsthmaMap: An interactive knowledge repository for mechanisms of asthma.
J Allergy Clin Immunol;
147(3): 853-856, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33309742
5.
Translational models of lung disease.
Clin Sci (Lond);
128(4): 235-56, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25328010
6.
In vitro pharmacological characterization of vilanterol, a novel long-acting ß2-adrenoceptor agonist with 24-hour duration of action.
J Pharmacol Exp Ther;
344(1): 218-30, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23131596
7.
AsthmaMap: An expert-driven computational representation of disease mechanisms.
Clin Exp Allergy;
48(8): 916-918, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30133857
8.
Low levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids.
ERJ Open Res;
9(5)2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37868143
9.
A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma.
Pulm Pharmacol Ther;
25(6): 453-64, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23046662
10.
In vivo characterization of GSK256066, a high-affinity inhaled phosphodiesterase 4 inhibitor.
J Pharmacol Exp Ther;
337(1): 137-44, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21205924
11.
GSK256066, an exceptionally high-affinity and selective inhibitor of phosphodiesterase 4 suitable for administration by inhalation: in vitro, kinetic, and in vivo characterization.
J Pharmacol Exp Ther;
337(1): 145-54, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21205923
12.
Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.
Bioorg Med Chem Lett;
21(10): 3037-40, 2011 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21482467
13.
The identification of a novel phosphodiesterase 4 inhibitor, 1-ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (EPPA-1), with improved therapeutic index using pica feeding in rats as a measure of emetogenicity.
J Pharmacol Exp Ther;
330(3): 922-31, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19498103
14.
Selective inducible nitric oxide synthase inhibition has no effect on allergen challenge in asthma.
Am J Respir Crit Care Med;
176(10): 988-93, 2007 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17717202
15.
GW274150, a novel and highly selective inhibitor of the inducible isoform of nitric oxide synthase (iNOS), shows analgesic effects in rat models of inflammatory and neuropathic pain.
Pain;
120(1-2): 170-181, 2006 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-16360270
16.
GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo.
Br J Pharmacol;
145(3): 301-12, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15778742
17.
Challenges for the development of new treatments for severe asthma: a pharmaceutical perspective.
Curr Pharm Des;
17(7): 699-702, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21406057
18.
Inhibition of iNOS activity by 1400W decreases glutamate release and ameliorates stroke outcome after experimental ischemia.
Neurobiol Dis;
18(2): 375-84, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15686966
19.
Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene.
Mol Pharmacol;
67(6): 1920-34, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15738310
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