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1.

Period2 3'-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation.

Yoo, Seung-Hee; Kojima, Shihoko; Shimomura, Kazuhiro; Koike, Nobuya; Buhr, Ethan D; Furukawa, Tadashi; Ko, Caroline H; Gloston, Gabrielle; Ayoub, Christopher; Nohara, Kazunari; Reyes, Bryan A; Tsuchiya, Yoshiki; Yoo, Ook-Joon; Yagita, Kazuhiro; Lee, Choogon; Chen, Zheng; Yamazaki, Shin; Green, Carla B; Takahashi, Joseph S.

Proc Natl Acad Sci U S A; 114(42): E8855-E8864, 2017 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-28973913

2.

Impact of Sequence Specificity of Spherical Nucleic Acids on Macrophage Activation in Vitro and in Vivo.

Guan, Chenxia M; Chinen, Alyssa B; Ferrer, Jennifer R; Ko, Caroline H; Mirkin, Chad A.

Mol Pharm; 16(10): 4223-4229, 2019 10 07.

Artículo en Inglés | MEDLINE | ID: mdl-31536368

3.

The Impact of Protein Corona Formation on the Macrophage Cellular Uptake and Biodistribution of Spherical Nucleic Acids.

Chinen, Alyssa B; Guan, Chenxia M; Ko, Caroline H; Mirkin, Chad A.

Small; 13(16)2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-28196309

4.

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.

Marcheva, Biliana; Ramsey, Kathryn Moynihan; Buhr, Ethan D; Kobayashi, Yumiko; Su, Hong; Ko, Caroline H; Ivanova, Ganka; Omura, Chiaki; Mo, Shelley; Vitaterna, Martha H; Lopez, James P; Philipson, Louis H; Bradfield, Christopher A; Crosby, Seth D; JeBailey, Lellean; Wang, Xiaozhong; Takahashi, Joseph S; Bass, Joseph.

Nature; 466(7306): 627-31, 2010 Jul 29.

Artículo en Inglés | MEDLINE | ID: mdl-20562852

5.

The genetics of mammalian circadian order and disorder: implications for physiology and disease.

Takahashi, Joseph S; Hong, Hee-Kyung; Ko, Caroline H; McDearmon, Erin L.

Nat Rev Genet; 9(10): 764-75, 2008 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-18802415

6.

Long-Circulating Vasoactive 1,18-Octadecanedioic Acid-Terlipressin Conjugate.

Berger, Or; Choi, Wonmin; Ko, Caroline H; Thompson, Matthew P; Avram, Michael J; Scott, Daniel J; Hoare, Bradley L; Cridge, Riley; Wheatley, Mark; Bathgate, Ross A D; Batlle, Daniel; Gianneschi, Nathan C.

ACS Pharmacol Transl Sci; 7(5): 1252-1261, 2024 May 10.

Artículo en Inglés | MEDLINE | ID: mdl-38751631

7.

Emergence of noise-induced oscillations in the central circadian pacemaker.

Ko, Caroline H; Yamada, Yujiro R; Welsh, David K; Buhr, Ethan D; Liu, Andrew C; Zhang, Eric E; Ralph, Martin R; Kay, Steve A; Forger, Daniel B; Takahashi, Joseph S.

PLoS Biol; 8(10): e1000513, 2010 Oct 12.

Artículo en Inglés | MEDLINE | ID: mdl-20967239

8.

A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma.

Kumthekar, Priya; Ko, Caroline H; Paunesku, Tatjana; Dixit, Karan; Sonabend, Adam M; Bloch, Orin; Tate, Matthew; Schwartz, Margaret; Zuckerman, Laura; Lezon, Ray; Lukas, Rimas V; Jovanovic, Borko; McCortney, Kathleen; Colman, Howard; Chen, Si; Lai, Barry; Antipova, Olga; Deng, Junjing; Li, Luxi; Tommasini-Ghelfi, Serena; Hurley, Lisa A; Unruh, Dusten; Sharma, Nitya V; Kandpal, Manoj; Kouri, Fotini M; Davuluri, Ramana V; Brat, Daniel J; Muzzio, Miguel; Glass, Mitchell; Vijayakumar, Vinod; Heidel, Jeremy; Giles, Francis J; Adams, Ann K; James, C David; Woloschak, Gayle E; Horbinski, Craig; Stegh, Alexander H.

Sci Transl Med; 13(584)2021 03 10.

Artículo en Inglés | MEDLINE | ID: mdl-33692132

9.

Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior.

Hong, Hee-Kyung; Chong, Jason L; Song, Weimin; Song, Eun Joo; Jyawook, Amira A; Schook, Andrew C; Ko, Caroline H; Takahashi, Joseph S.

PLoS Genet; 3(2): e33, 2007 Feb 23.

Artículo en Inglés | MEDLINE | ID: mdl-17319750

10.

Attenuation of context-specific inhibition on reversal learning of a stimulus-response task in rats with neurotoxic hippocampal damage.

McDonald, Robert J; Ko, Caroline H; Hong, Nancy S.

Behav Brain Res; 136(1): 113-26, 2002 Oct 17.

Artículo en Inglés | MEDLINE | ID: mdl-12385796

11.

The significance of circadian phase for performance on a reward-based learning task in hamsters.

Ralph, Martin R; Ko, Caroline H; Antoniadis, Elena A; Seco, Petula; Irani, Farzin; Presta, Carmella; McDonald, Robert J.

Behav Brain Res; 136(1): 179-84, 2002 Oct 17.

Artículo en Inglés | MEDLINE | ID: mdl-12385803

12.

Memory for time of day (time memory) is encoded by a circadian oscillator and is distinct from other context memories.

Ralph, Martin R; Sam, Kevin; Rawashdeh, Omar A; Cain, Sean W; Ko, Caroline H.

Chronobiol Int; 30(4): 540-7, 2013 May.

Artículo en Inglés | MEDLINE | ID: mdl-23428333

13.

Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma.

Jensen, Samuel A; Day, Emily S; Ko, Caroline H; Hurley, Lisa A; Luciano, Janina P; Kouri, Fotini M; Merkel, Timothy J; Luthi, Andrea J; Patel, Pinal C; Cutler, Joshua I; Daniel, Weston L; Scott, Alexander W; Rotz, Matthew W; Meade, Thomas J; Giljohann, David A; Mirkin, Chad A; Stegh, Alexander H.

Sci Transl Med; 5(209): 209ra152, 2013 Oct 30.

Artículo en Inglés | MEDLINE | ID: mdl-24174328

14.

Nanotechnology for synthetic high-density lipoproteins.

Luthi, Andrea J; Patel, Pinal C; Ko, Caroline H; Mutharasan, R Kannan; Mirkin, Chad A; Thaxton, C Shad.

Trends Mol Med; 16(12): 553-60, 2010 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-21087901

15.

Casein kinase I epsilon gene transfer into the suprachiasmatic nucleus via electroporation lengthens circadian periods of tau mutant hamsters.

Wang, Haoran; Ko, Caroline H; Koletar, Margaret M; Ralph, Martin R; Yeomans, John.

Eur J Neurosci; 25(11): 3359-66, 2007 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-17553004

16.

Intercellular coupling confers robustness against mutations in the SCN circadian clock network.

Liu, Andrew C; Welsh, David K; Ko, Caroline H; Tran, Hien G; Zhang, Eric E; Priest, Aaron A; Buhr, Ethan D; Singer, Oded; Meeker, Kirsten; Verma, Inder M; Doyle, Francis J; Takahashi, Joseph S; Kay, Steve A.

Cell; 129(3): 605-16, 2007 May 04.

Artículo en Inglés | MEDLINE | ID: mdl-17482552

17.

Molecular components of the mammalian circadian clock.

Ko, Caroline H; Takahashi, Joseph S.

Hum Mol Genet; 15 Spec No 2: R271-7, 2006 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-16987893

18.

The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude.

Vitaterna, Martha Hotz; Ko, Caroline H; Chang, Anne-Marie; Buhr, Ethan D; Fruechte, Ethan M; Schook, Andrew; Antoch, Marina P; Turek, Fred W; Takahashi, Joseph S.

Proc Natl Acad Sci U S A; 103(24): 9327-32, 2006 Jun 13.

Artículo en Inglés | MEDLINE | ID: mdl-16754844

19.

Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice.

McDearmon, Erin L; Patel, Kush N; Ko, Caroline H; Walisser, Jacqueline A; Schook, Andrew C; Chong, Jason L; Wilsbacher, Lisa D; Song, Eun J; Hong, Hee-Kyung; Bradfield, Christopher A; Takahashi, Joseph S.

Science; 314(5803): 1304-8, 2006 Nov 24.

Artículo en Inglés | MEDLINE | ID: mdl-17124323

20.

A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo.

Yoo, Seung-Hee; Ko, Caroline H; Lowrey, Phillip L; Buhr, Ethan D; Song, Eun-joo; Chang, Suhwan; Yoo, Ook Joon; Yamazaki, Shin; Lee, Choogon; Takahashi, Joseph S.

Proc Natl Acad Sci U S A; 102(7): 2608-13, 2005 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-15699353

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