Detalles de la búsqueda
1.
Systematic evaluation of lecithin:cholesterol acyltransferase binding sites in apolipoproteins via peptide based nanodiscs: regulatory role of charged residues at positions 4 and 7.
PLoS Comput Biol;
20(5): e1012137, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38805510
2.
Development of Robust Cationic Light-Activated Thermosensitive Liposomes: Choosing the Right Lipids.
Mol Pharm;
20(11): 5728-5738, 2023 11 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37874965
3.
Mechanistic Insights into the Activation of Lecithin-Cholesterol Acyltransferase in Therapeutic Nanodiscs Composed of Apolipoprotein A-I Mimetic Peptides and Phospholipids.
Mol Pharm;
19(11): 4135-4148, 2022 11 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36111986
4.
Positive allosteric modulators of lecithin: Cholesterol acyltransferase adjust the orientation of the membrane-binding domain and alter its spatial free energy profile.
PLoS Comput Biol;
17(3): e1008426, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33720934
5.
Mechanistic Insight into How PEGylation Reduces the Efficacy of pH-Sensitive Liposomes from Molecular Dynamics Simulations.
Mol Pharm;
18(7): 2612-2621, 2021 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34096310
6.
Rigorous Computational Study Reveals What Docking Overlooks: Double Trouble from Membrane Association in Protein Kinase C Modulators.
J Chem Inf Model;
60(11): 5624-5633, 2020 11 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32915560
7.
Interaction of lecithin:cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I-derived peptides.
J Lipid Res;
59(4): 670-683, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29438987
8.
The biophysical properties of ethanolamine plasmalogens revealed by atomistic molecular dynamics simulations.
Biochim Biophys Acta;
1858(1): 97-103, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26522077
9.
A computational approach for studying antibody-antigen interactions without prior structural information: the anti-testosterone binding antibody as a case study.
Proteins;
85(2): 322-331, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27936519
10.
Interactions between Chloramphenicol, Carrier Polymers, and Bacteria-Implications for Designing Electrospun Drug Delivery Systems Countering Wound Infection.
Mol Pharm;
14(12): 4417-4430, 2017 12 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29099601
11.
How anacetrapib inhibits the activity of the cholesteryl ester transfer protein? Perspective through atomistic simulations.
PLoS Comput Biol;
10(11): e1003987, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25412509
12.
Far-red light-triggered cargo release from liposomes b ound to a photosensitizer-cellulose nanofiber hydrogel.
Carbohydr Polym;
336: 122134, 2024 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38670761
13.
Interfacial properties of high-density lipoprotein-like lipid droplets with different lipid and apolipoprotein A-I compositions.
Biophys J;
104(10): 2193-201, 2013 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23708359
14.
Lipid exchange mechanism of the cholesteryl ester transfer protein clarified by atomistic and coarse-grained simulations.
PLoS Comput Biol;
8(1): e1002299, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22253581
15.
Rational design of a polysaccharide-based viral mimicry nanocomplex for potent gene silencing in inflammatory tissues.
J Control Release;
357: 120-132, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36963635
16.
Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C-Targeted Agonists.
J Med Chem;
66(7): 4588-4602, 2023 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37010933
17.
Interfacial tension and surface pressure of high density lipoprotein, low density lipoprotein, and related lipid droplets.
Biophys J;
103(6): 1236-44, 2012 Sep 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-22995496
18.
Role of neutral lipids in tear fluid lipid layer: coarse-grained simulation study.
Langmuir;
28(49): 17092-100, 2012 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23151187
19.
Insights into the behavior of unsaturated diacylglycerols in mixed lipid bilayers in relation to protein kinase C activation-A molecular dynamics simulation study.
Biochim Biophys Acta Biomembr;
1864(9): 183961, 2022 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35568204
20.
Membrane simulations mimicking acidic pH reveal increased thickness and negative curvature in a bilayer consisting of lysophosphatidylcholines and free fatty acids.
Biochim Biophys Acta;
1798(5): 938-46, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20132791