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1.
J Stroke Cerebrovasc Dis ; 30(10): 106052, 2021 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-34419833

RESUMEN

OBJECTIVE: Whether weight loss during hospitalization is associated with improvement in activities of daily living (ADL) in overweight and obese stroke patients remains unclear. This study investigated the association between decreases in body mass index (BMI), fat-free mass (FFM), and fat mass (FM) and ADL improvement. MATERIALS AND METHODS: In this cross-sectional study, we analyzed data of patients admitted to acute care hospitals with stroke. Patients were classified into two groups based on their change in BMI during their hospital stay (i.e. decreased or nondecreased group). To control and adjust for patient characteristics and confounders, we created an inverse probability-weighted (IPW) model using propensity scoring, which was used to compare the Functional Independence Measure Motor (FIM-M) efficacy between the two groups. We also compared FFM and FM between admission and discharge in each group. RESULTS: A total of 556 patients were analyzed, among whom 391 (70.3%) had a decrease in BMI and 165 (29.7%) had a nondecrease. After IPW adjustment, efficiency of FIM-M was significantly higher in the nondecreased group as compared to that in the decreased group (median: 0.44 vs. 0.29, P < 0.001). FFM and FM were significantly decreased from admission to discharge in the decreased group, but there was no significanct difference observed in the nondecreased group. Preserving BMI during hospitalization was associated with a positive improvement in ADL in overweight and obese stroke patients undergoing rehabilitation. CONCLUSIONS: Risks and benefits of weight loss should be balanced in nutritional care and rehabilitation for overweight and obese stroke patients.


Asunto(s)
Actividades Cotidianas , Obesidad/terapia , Rehabilitación de Accidente Cerebrovascular , Accidente Cerebrovascular/terapia , Pérdida de Peso , Adiposidad , Anciano , Anciano de 80 o más Años , Índice de Masa Corporal , Estudios Transversales , Evaluación de la Discapacidad , Femenino , Estado Funcional , Hospitalización , Humanos , Japón , Masculino , Persona de Mediana Edad , Obesidad/complicaciones , Obesidad/diagnóstico , Obesidad/fisiopatología , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/diagnóstico , Accidente Cerebrovascular/fisiopatología , Factores de Tiempo , Resultado del Tratamiento
2.
Med Princ Pract ; 30(5): 493-500, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34348295

RESUMEN

OBJECTIVE: The aim of this study was to investigate the relationship between energy intake and changes in thigh echo intensity (TEI) during the acute phase of stroke in older patients with hemiplegia. SUBJECTS AND METHODS: Older hemiplegic inpatients with stroke were enrolled in this post hoc analysis of a prospective observational study. Patients were divided into 2 groups according to energy intake during the 7 days after admission as follows: energy sufficient (ES) and energy insufficient (EIS) groups. The outcome was the rate of changes in TEI of the paralyzed and nonparalyzed sides between admission and after 4 weeks. A decrease in skeletal muscle quality is defined as an increase in intramuscular adipose tissues, which shows as an increase in echo intensity. RESULTS: The study included 44 males and 39 females (median age 81 years). The rate of change of TEI in each group was as follows: +4.5% in the ES/paralyzed group, +6.7% in the EIS/paralyzed group, -0.9% in the ES/nonparalyzed group, and +4.4% in the EIS/nonparalyzed group. The univariate analyses showed no significant difference in the rate of change in TEI between ES and EIS groups in both paralyzed side (p = 0.190) and nonparalyzed side (p = 0.183). Multivariate analysis showed that higher energy intake was associated with a smaller increase in the rate of change in TEI on the nonparalyzed side (B = -4.115, 95% confidence interval, -7.127 to -1.103). CONCLUSIONS: Higher energy intake during 7 days after admission was associated with a smaller increase in the rate of change in TEI on the nonparalyzed side upon admission and after 4 weeks.


Asunto(s)
Ingestión de Energía/fisiología , Hemiplejía/etiología , Músculo Esquelético/diagnóstico por imagen , Accidente Cerebrovascular/complicaciones , Muslo/diagnóstico por imagen , Tejido Adiposo , Anciano , Anciano de 80 o más Años , Femenino , Fémur/diagnóstico por imagen , Hemiplejía/diagnóstico por imagen , Humanos , Masculino , Estudios Prospectivos , Accidente Cerebrovascular/diagnóstico por imagen , Ultrasonografía/métodos
3.
J Stroke Cerebrovasc Dis ; 25(6): 1335-41, 2016 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-26987486

RESUMEN

BACKGROUND: The aim of the present study was to establish whether high nutritional-related risk on admission predicts less improvement of Functional Independence Measure (FIM) in geriatric stroke patients. METHODS: We performed a retrospective cohort study of patients admitted for stroke at 5 major hospitals in the Noto district of Japan from July 2009 to June 2013. Patients were divided into 2 groups according to Geriatric Nutritional Risk Index (GNRI) at admission. Patient characteristics were compared between the low GNRI (<92) and high GNRI (≥92) groups. We assessed nutritional status using GNRI and activities of daily living using the FIM. RESULTS: A total of 540 participants (mean age, 80 years; interquartile range, 75-85 years) were included in the present study. Patients were admitted because of cerebral infarction (394 patients), intracerebral hemorrhage (123 patients), and subarachnoid hemorrhage (23 patients). Univariate analysis of FIM gain demonstrated significant differences between groups. Multivariate analysis of FIM gain adjusting for confounding factors demonstrated age (ß = -.139; 95% confidence interval [CI] = -.629 to -.140), cerebral infarction (ß = -.264; 95% CI = -12.956 to -6.729), National Institutes of Health Stroke Scale (ß = -.180; 95% CI = -.688 to -.248), and GNRI score (ß = .089; 95% CI = .010-.347) as independent factors associated with FIM gain (P < .05 for all). CONCLUSIONS: GNRI at admission may independently predict FIM gain. Poor nutritional status is a predictor of lower FIM improvement in geriatric stroke patients.


Asunto(s)
Hemorragia Cerebral/fisiopatología , Infarto Cerebral/fisiopatología , Estado Nutricional , Hemorragia Subaracnoidea/fisiopatología , Actividades Cotidianas , Factores de Edad , Anciano , Anciano de 80 o más Años , Hemorragia Cerebral/diagnóstico , Hemorragia Cerebral/terapia , Infarto Cerebral/diagnóstico , Infarto Cerebral/terapia , Distribución de Chi-Cuadrado , Evaluación de la Discapacidad , Femenino , Evaluación Geriátrica , Humanos , Japón , Modelos Lineales , Masculino , Análisis Multivariante , Evaluación Nutricional , Admisión del Paciente , Valor Predictivo de las Pruebas , Recuperación de la Función , Estudios Retrospectivos , Medición de Riesgo , Factores de Riesgo , Rehabilitación de Accidente Cerebrovascular , Hemorragia Subaracnoidea/diagnóstico , Hemorragia Subaracnoidea/terapia , Factores de Tiempo , Resultado del Tratamiento
4.
Nutrients ; 16(2)2024 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-38257116

RESUMEN

Malnutrition is a common condition in geriatric rehabilitation settings; however, the accuracy and predictive validity of the measures to identify malnutrition have not been established. The current scoping review followed the Joanna Briggs Institute's evidence synthesis manual and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Reviews checklist. Literature published through September 2023 was searched using MEDLINE and CINAHL. The inclusion criteria selected studies reporting malnutrition measures, which include static body weight and weight loss. Identified tools were classified as nutritional screening tools, nutritional assessment tools, or diagnostic criteria. The domains of each tool/criterion and their accuracy and predictive validity were extracted. Fifty-six articles fulfilled the inclusion criteria, and six nutritional screening tools, three nutritional assessment tools, and three diagnostic criteria for malnutrition were identified. These measures consisted of various phenotypes, e.g., weight loss, causes such as inflammation/disease, and risk factors of malnutrition, e.g., functional impairment. The predictive validity of nutritional screening tools (n = 6) and malnutrition diagnostic criteria (n = 5) were inconsistently reported, whereas those for nutritional assessment tools were scarce (n = 1). These findings highlight the need to distinguish the functional impairment of nutritional origin from that of non-nutritional origin in nutritional assessment procedures, and the need to study the accuracy and the predictive validity of these measures in geriatric rehabilitation patients.


Asunto(s)
Desnutrición , Evaluación Nutricional , Humanos , Anciano , Estado Nutricional , Desnutrición/diagnóstico , Peso Corporal , Pérdida de Peso
5.
Clin Nutr ; 43(8): 1825-1843, 2024 Jun 25.
Artículo en Inglés | MEDLINE | ID: mdl-38959660

RESUMEN

BACKGROUND & AIMS: Sarcopenia, characterized by loss of muscle mass and decreased muscle strength, significantly affects adults but also influences pediatric health. However, definitions for low muscle mass, decreased strength, and sarcopenia in children are less established, impacting interventions for improving health outcomes. The objective of this scoping review is synthesize the existing literature on the diagnostic criteria, prevalence and clinical outcomes of sarcopenia. METHODS: A scoping review, following the PRISMA extension for scoping reviews, examined pediatric sarcopenia literature until June 2023. The literature search was performed using MEDLINE and the Cochrane Central Register of Controlled Trials with the last search conducted on June 30, 2023. Criteria included studies on aged 0-20 years, covering healthy subjects, acutely ill patients, and chronic disease cases excluding specific conditions like neuromuscular diseases or prematurity. RESULTS: Initial search found 503 studies, finally, we included 56 studies. Most studies diagnosed sarcopenia using skeletal muscle mass indicators like total psoas muscle area from Computed Tomography or Magnetic Resonance Imaging. Around half of the longitudinal studies highlighted sarcopenia as a risk factor for various clinical outcomes, predominantly in hospitalized patients. However, cutoff values for sarcopenia indicators lacked consistency, with studies employing diverse percentile-based measurements or z-scores. CONCLUSION: Pediatric sarcopenia diagnosis primarily relies on skeletal muscle mass, with identified links to future clinical outcomes in specific conditions. The lack of standardized cutoffs for sarcopenia indicators underscores the necessity for age, gender, and race-specific cutoff values derived from studies establishing reference values for muscle mass and strength across diverse pediatric populations.

6.
Nutrients ; 15(8)2023 Apr 14.
Artículo en Inglés | MEDLINE | ID: mdl-37111112

RESUMEN

Rehabilitation nutrition is expected to help treat frailty, undernutrition, and sarcopenia [...].


Asunto(s)
Fragilidad , Desnutrición , Sarcopenia , Humanos , Anciano , Estado Nutricional , Desnutrición/prevención & control , Evaluación Geriátrica
7.
Nutrients ; 15(23)2023 Nov 24.
Artículo en Inglés | MEDLINE | ID: mdl-38068766

RESUMEN

Frailty, sarcopenia, and malnutrition are highly prevalent among the older population [...].


Asunto(s)
Fragilidad , Desnutrición , Sarcopenia , Humanos , Fragilidad/epidemiología , Sarcopenia/epidemiología , Desnutrición/epidemiología , Apoyo Nutricional
8.
Clin Nutr ESPEN ; 57: 173-180, 2023 10.
Artículo en Inglés | MEDLINE | ID: mdl-37739653

RESUMEN

BACKGROUND AND AIMS: Ultrasound has been used primarily as a tool for body composition measurement in the field of clinical nutrition. Although many recent reports have demonstrated that ultrasound could be a useful tool for nutritional assessment, it is not well incorporated into registered dietitians' (RDs) practice. The aim of this review was to summarize the usefulness of ultrasound in assessing body composition and nutritional status and in nutritional management by RDs. METHODS: Studies on ultrasonography, nutritionists, body composition, nutritional assessment, and diet therapy was searched using the MEDLINE databases. RESULTS: After reviewing the articles, we categorized them into the following topics; 1) principles of muscle measurement using the ultrasound, types of muscle that can be measured, 2) indices of muscle and muscle mass and quality as assessed using ultrasound and its relationship to nutritional indicator, 3) diagnosis of the Global Leadership Initiative on Malnutrition (GLIM) criteria malnutrition using ultrasound, 4) practical nutritional management using ultrasound and 5) education and issues for ultrasound implementation. Ultrasound can evaluate low body mass index, unintentional loss of body weight, low skeletal muscle mass index, decreased food intake/assimilation, and disease burden/inflammation, all which are essential items of the phenotypic and etiologic criteria of the GLIM. CONCLUSION: Ultrasound may be useful for RDs to perform body composition measurement, nutritional assessment, and nutritional management. It will be important to identify the cutoff values for ultrasound-based measurements of muscle mass. In order for RDs to perform a body composition measurement, nutritional assessment, and nutritional management using ultrasound, educational issues need to be addressed.


Asunto(s)
Evaluación Nutricional , Nutricionistas , Humanos , Estado Nutricional , Ultrasonografía , Composición Corporal
9.
Nutrients ; 15(22)2023 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-38004182

RESUMEN

Malnutrition prevails among patients with heart failure (HF), increasing the likelihood of functional decline. We assessed the predictive value of the Hemoglobin-Geriatric Nutritional Risk Index (H-GNRI)-combining hemoglobin and the Geriatric Nutritional Risk Index (GNRI)-on prognosis in older patients with HF. We used the JMDC multicenter database to examine the potential associations between malnutrition risk and other outcome measures. The patients were categorized as low- (H-GNRI score = 0), intermediate- (H-GNRI score = 1), or high-risk (H-GNRI score = 2) based on their H-GNRI scores. The primary outcome measure was the Barthel Index (BI) gain; the secondary outcomes included the BI at discharge, the BI efficiency, length of hospital stay, in-hospital mortality, discharge to home or a nursing home, and hospitalization-associated disability. We analyzed 3532 patients, with 244 being low-risk, 952 being intermediate-risk, and 2336 being high-risk patients. The high-risk group of patients had significantly lower BI values at discharge, lower BI gains, reduced BI efficiency values, and prolonged hospital stays compared to those in the low-risk group. The high-risk patients also had higher in-hospital mortality rates, lower rates of discharge to home or a nursing home, and greater incidences of a hospitalization-associated disability in comparison to the low-risk group. The H-GNRI may serve as a valuable tool for determining prognoses for patients with HF.


Asunto(s)
Insuficiencia Cardíaca , Desnutrición , Anciano , Humanos , Evaluación Geriátrica , Hemoglobinas , Desnutrición/epidemiología , Evaluación Nutricional , Estado Nutricional , Pronóstico , Estudios Retrospectivos , Factores de Riesgo , Estudios Multicéntricos como Asunto , Bases de Datos como Asunto
10.
J Spinal Cord Med ; : 1-8, 2023 May 17.
Artículo en Inglés | MEDLINE | ID: mdl-37195196

RESUMEN

OBJECTIVE: To investigate the association between sufficient energy intake and improvement in activities of daily living (ADL) after hospitalization in patients with cervical spinal cord injury (CSCI) undergoing post-acute rehabilitation. DESIGN: Retrospective cohort study. SETTING: Post-acute care hospital from September 2013 to December 2020. PARTICIPANTS: Patients with CSCI admitted to a post-acute care hospital for rehabilitation. INTERVENTION: Not applicable. OUTCOME MEASURE(S): Multiple regression analysis was performed to investigate the relationship of sufficient energy intake to Motor Functional Independence Measure (mFIM) gain, mFIM score at discharge, and body weight change during hospitalization. RESULTS: In total, 116 patients (104 men and 12 women), median age: 55 (interquartile range [IQR] 41-65) years were included in the analysis. Then, 68 (58.6%) were in the energy-sufficient group, and 48 (41.4%) patients were classified under the energy-deficient group. The two groups did not significantly differ in terms of mFIM gain and mFIM score at discharge. The energy-sufficient group maintained body weight change during hospitalization than the energy-deficient group (0.6 [-2.0-2.0] vs. -1.9 [-4.0--0.3], P < 0.001). Multiple regression analysis showed no association between sufficient energy intake and outcomes. CONCLUSION: Sufficient energy intake within the first 3 days of admission did not affect ADL improvement during hospitalization in patients with a post-cute CSCI undergoing rehabilitation.

11.
Nutrients ; 15(5)2023 Mar 06.
Artículo en Inglés | MEDLINE | ID: mdl-36904290

RESUMEN

This retrospective cohort study examined the effects of undernutrition on swallowing function and activities of daily living in hospitalized patients. Data from the Japanese Sarcopenic Dysphagia Database were used, and hospitalized patients aged ≥20 years with dysphagia were included in the analysis. Participants were assigned to the undernutrition or normal nutritional status group based on the Global Leadership Initiative on Malnutrition criteria. The primary outcome was the Food Intake Level Scale change, and the secondary outcome was the Barthel Index change. Among 440 residents, 281 (64%) were classified under the undernutrition group. The undernutrition group had a significantly higher Food Intake Level Scale score at baseline and Food Intake Level Scale change (p = 0.001) than the normal nutritional status group. Undernutrition was independently associated with the Food Intake Level Scale change (B = -0.633, 95% confidence interval = -1.099 to -0.167) and the Barthel Index change (B = -8.414, 95% confidence interval = -13.089 to -3.739). This was defined as the period from the date of admission to the hospital until discharge or 3 months later. Overall, our findings indicate that undernutrition is associated with reduced improvement in swallowing function and the ability to perform activities of daily living.


Asunto(s)
Trastornos de Deglución , Desnutrición , Sarcopenia , Humanos , Deglución , Trastornos de Deglución/complicaciones , Actividades Cotidianas , Estudios Retrospectivos , Pueblos del Este de Asia , Estado Nutricional , Desnutrición/complicaciones
12.
JMA J ; 5(1): 62-71, 2022 Jan 17.
Artículo en Inglés | MEDLINE | ID: mdl-35224261

RESUMEN

INTRODUCTION: To date, no studies have assessed the prognostic ability of nutritional indicators to predict changes in quadriceps muscle thickness (QMT). Hence, this study aimed to identify the optimal nutritional indicators for predicting the change in QMT during the acute phase in patients with stroke. METHODS: This retrospective cohort study was a post-hoc analysis of a prospective study in a single hospital. The Geriatric Nutritional Risk Index (GNRI), Controlling Nutritional Status (CONUT), and Mini Nutritional Assessment - Short Form (MNA-SF) were assessed. The primary outcome was the 2-week change in QMT from the time of admission in the paralytic and non-paralytic sides. QMT was evaluated at the rectus femoris and the vastus intermedius in both lower limbs using B-mode ultrasound imaging. The sum of both measurements was defined as QMT. Univariate and multivariate analyses were performed to confirm the effects of nutritional risks assessed by each nutritional indicator on QMT change. RESULTS: We analyzed 118 patients (mean age, 80.2 ± 8.8 years). No significant difference was found in QMT change in the non-paralytic limbs between the groups stratified based on GNRI and CONUT. However, the difference was significant between the malnourished and normal nutritional status in patients categorized by MNA-SF. After adjusting for potential confounders, a significant association was found between MNA-SF and change in QMT (malnourished vs. normal nutritional status; B = -0.143; 95% confidence interval [CI], -0.254 to -0.031) in the non-paralytic limbs. MNA-SF was not independently associated with change in QMT in the paralytic limb. Furthermore, GNRI and CONUT were not independently associated with change in QMT in both paralytic and non-paralytic limbs. CONCLUSIONS: Although MNA-SF might be useful for predicting the QMT change in non-paralytic limbs, GNRI and CONUT cannot predict the QMT change in either the paralytic or non-paralytic limb.

13.
Nutrients ; 14(17)2022 Sep 04.
Artículo en Inglés | MEDLINE | ID: mdl-36079911

RESUMEN

Malnutrition is associated with poor functional outcomes in residents in long-term care facilities. The integrated facility for medical and long-term care (IFMLC) is a new Japanese long-term care facility where medical services can be provided. This study aimed to investigate the prevalence of malnutrition diagnosed based on the Global Leadership Initiative on Malnutrition (GLIM) criteria and its association with activities of daily living (ADL) in older residents in IFMLC. In this cross-sectional study of older residents, we diagnosed mild and severe malnutrition using the GLIM criteria and assessed ADLs using the Barthel index (BI). Multivariate regression analysis was used to investigate the relationship between BI score and GLIM-defined malnutrition. A total of 117 older residents (84 women; median age, 88 years) were analyzed in this study. The prevalence values of mild and severe malnutrition were 29% and 18%, respectively. Multivariate analyses for the BI score after adjusting for potential confounders showed that mild and severe malnutrition were independently associated with BI score (B = −6.113, p < 0.046; B = −8.411, p = 0.015, respectively). GLIM-defined malnutrition is negatively associated with ADLs in older residents in IFMLC.


Asunto(s)
Desnutrición , Desnutrición Proteico-Calórica , Actividades Cotidianas , Anciano , Anciano de 80 o más Años , Estudios Transversales , Femenino , Humanos , Liderazgo , Cuidados a Largo Plazo , Desnutrición/diagnóstico , Desnutrición/epidemiología , Evaluación Nutricional , Estado Nutricional , Prevalencia
14.
Nutrients ; 14(20)2022 Oct 11.
Artículo en Inglés | MEDLINE | ID: mdl-36296920

RESUMEN

This study investigated the paradox of high visceral fat mass increasing severe complications but improving long-term prognosis after radical gastrectomy for gastric cancer. This was a retrospective cohort study of consecutive patients with primary stage I-III gastric cancer who underwent gastrectomy between April 2008 and June 2018. The visceral adipose tissue index (VAI) was calculated by dividing the visceral fat mass preoperatively measured on computed tomography by the square of the height. Patients with VAIs below the median cut-off value were classified as low-VAI, while those above it were classified as high-VAI. We compared the postoperative complication rate and overall survival (OS) in the low- and high-VAI groups after adjusting patient characteristics using propensity score matching (PSM). There were 155 patients in both groups after PSM. After matching, there was no significant difference in factors other than BMI and VAI that were not adjusted. The high-VAI group had more severe postoperative complications (p = 0.018), but the OS was significantly better in the high-VAI group (hazard ratio 0.611, 95%CI 0.403-0.928, p = 0.021). Preoperative high visceral fat mass not only increased severe complications, but also improved OS after gastrectomy in patients with advanced gastric cancer.


Asunto(s)
Neoplasias Gástricas , Humanos , Neoplasias Gástricas/complicaciones , Grasa Intraabdominal/diagnóstico por imagen , Puntaje de Propensión , Estudios Retrospectivos , Gastrectomía/métodos , Pronóstico , Complicaciones Posoperatorias/etiología
15.
J Gen Fam Med ; 23(4): 205-216, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-35800646

RESUMEN

Diagnostic reasoning is the thought process used to arrive at a diagnosis based on symptoms, examination findings, and laboratory values. Diagnosis is categorized as nonanalytic reasoning (intuition) and analytic reasoning (analysis). Rehabilitation nutrition involves the diagnosis of nutritional disorders, sarcopenia, and excess or deficient nutrient intake. There is usually only one correct answer for the presence or absence of these. On the other hand, there may be no single correct answer for the causes of anorexia, weight loss, or sarcopenia, and analytical reasoning is required. In this case, diagnostic reasoning involves hypotheses. Simply using nutritional supplements without performing diagnostic reasoning about these causes is like prescribing antipyretic analgesics to a patient with a headache without diagnosing the cause of the headache. To maximize function and quality of life in rehabilitation nutrition, it is necessary to suspect the common causes of anorexia, weight loss, and sarcopenia in all cases.

16.
Nutrients ; 14(22)2022 Nov 09.
Artículo en Inglés | MEDLINE | ID: mdl-36432408

RESUMEN

Rehabilitation nutrition is a proposed intervention strategy to improve nutritional status and physical function. However, rehabilitation nutrition in patients with cachexia and protein-energy wasting (PEW), which are the main nutrition-related problems in patients with chronic kidney disease (CKD), has not been fully clarified. Therefore, this review aimed to summarize the current evidence and interventions related to rehabilitation nutrition for cachexia and PEW in patients with CKD. CKD is a serious condition worldwide, with a significant impact on patient prognosis. In addition, CKD is easily complicated by nutrition-related problems such as cachexia and PEW owing to disease background- and treatment-related factors, which can further worsen the prognosis. Although nutritional management and exercise therapy are reportedly effective for cachexia and PEW, the effectiveness of combined nutrition and exercise interventions is less clear. In the future, rehabilitation nutrition addressing the nutritional problems associated with CKD will become more widespread as more scientific evidence accumulates. In clinical practice, early intervention in patients with CKD involving both nutrition and exercise after appropriate assessment may be necessary to improve patient outcomes.


Asunto(s)
Caquexia , Insuficiencia Renal Crónica , Humanos , Caquexia/etiología , Caquexia/terapia , Estado Nutricional , Diálisis Renal/efectos adversos , Insuficiencia Renal Crónica/complicaciones , Insuficiencia Renal Crónica/terapia , Ejercicio Físico
17.
Nutrients ; 14(22)2022 Nov 10.
Artículo en Inglés | MEDLINE | ID: mdl-36432427

RESUMEN

Energy intake and rehabilitation time individually contribute to the improvement of activities of daily living (ADL). This study aimed to investigate the additive effect of energy intake and rehabilitation time on ADL improvement in acute stroke patients with sarcopenia. The study included 140 patients (mean age 82.6 years, 67 men) with stroke. Energy intake during the first week of hospitalization was classified as "Sufficiency" or "Shortage" based on the reported cutoff value and rehabilitation time was classified as "Long" or "Short" based on the median. The study participants were categorized into four groups based on the combination of energy intake and rehabilitation time. The primary outcome was the gain of functional independence measure (FIM) motor during hospitalization. The secondary outcomes were length of stay and home discharge rates. Multivariate analysis was performed with primary/secondary outcomes as the dependent variable, and the effect of each group on the outcome was examined. Multivariate analysis showed that "long rehabilitation time and sufficient energy intake" (ß = 0.391, p < 0.001) was independently associated with the gain of FIM motor items. The combination of high energy intake and sufficient rehabilitation time was associated with ADL improvement in acute stroke patients with sarcopenia.


Asunto(s)
Sarcopenia , Rehabilitación de Accidente Cerebrovascular , Accidente Cerebrovascular , Masculino , Humanos , Anciano de 80 o más Años , Actividades Cotidianas , Accidente Cerebrovascular/complicaciones , Ingestión de Energía
18.
Nutrients ; 14(22)2022 Nov 10.
Artículo en Inglés | MEDLINE | ID: mdl-36432433

RESUMEN

Low body mass index (BMI) is an independent predictor of prolonged hospital stay and mortality in patients with chronic obstructive pulmonary disease (COPD). However, to the best of our knowledge, no studies have examined the validity of Asian BMI cutoff values for classifying severity based on the Global Leadership Initiative on Malnutrition (GLIM) criteria in patients with acute COPD exacerbations. This study sought to validate whether Asian BMI cutoff values can accurately predict 30-day in-hospital mortality, length of stay, and 90-day readmission outcomes for patients with acute COPD exacerbations. The present retrospective cohort study was conducted using a large claims database created by the JMDC. Patients were classified into three groups according to the severity of low BMI assessed using Asian BMI cutoff values. As a result, 624 (29.4%) had severely low BMI, and 444 (20.9%) had moderately low BMI. The severity of low BMI, as assessed by the Asian BMI cutoff values used in the GLIM criteria, was independently associated with 30-day in-hospital mortality (moderately low BMI: HR, 1.87; 95% CI, 1.13−3.08; p = 0.014 and severely low BMI: HR, 2.55; 95% CI, 1.66−3.92; p < 0.001). The Asian BMI cutoff values used to classify the severity of malnutrition in the GLIM criteria are clinically functional for predicting the prognosis of patients with acute COPD exacerbations.


Asunto(s)
Desnutrición , Enfermedad Pulmonar Obstructiva Crónica , Humanos , Índice de Masa Corporal , Estudios Retrospectivos , Liderazgo , Desnutrición/diagnóstico , Desnutrición/complicaciones , Pérdida de Peso
19.
Nutrients ; 14(21)2022 Oct 26.
Artículo en Inglés | MEDLINE | ID: mdl-36364757

RESUMEN

The accuracy of body mass index (BMI) for sarcopenic dysphagia diagnosis, which remains unknown, was evaluated in this study among patients with dysphagia. We conducted a 19-site cross-sectional study. We registered 467 dysphagic patients aged ≥ 20 years. Sarcopenic dysphagia was assessed using a reliable and validated diagnostic algorithm. BMI was assessed using the area under the curve (AUC) in the receiver operating characteristic analysis to determine diagnostic accuracy for sarcopenic dysphagia. The study included 460 patients (median age, 83.0 years (76.0−88.0); men, 49.8%). The median BMI was 19.9 (17.3−22.6) kg/m2. Two hundred eighty-four (61.7%) patients had sarcopenic dysphagia. The AUC for sarcopenic dysphagia was 0.60−0.62 in the overall patients, male, female, and patients aged ≥ 65 years The BMI cut-off value for sarcopenic dysphagia diagnosis was 20.1 kg/m2 in the overall patients (sensitivity, 58.1%; specificity, 60.2%) and patients aged ≥ 65 years (sensitivity, 59.8%; specificity, 61.8%). Conclusion: Although the AUC, sensitivity and specificity of BMI for sarcopenic dysphagia diagnosis was approximately 0.6, BMI < 20.0 kg/m2 might be a predictor for sarcopenic dysphagia. In clinical settings, if patients with dysphagia have a BMI < 20.0 kg/m2, then sarcopenic dysphagia should be suspected as early as possible after admission.


Asunto(s)
Trastornos de Deglución , Sarcopenia , Humanos , Masculino , Femenino , Anciano de 80 o más Años , Sarcopenia/complicaciones , Sarcopenia/diagnóstico , Índice de Masa Corporal , Estudios Transversales , Trastornos de Deglución/diagnóstico , Trastornos de Deglución/etiología , Sensibilidad y Especificidad
20.
Clin Nutr ESPEN ; 52: 322-330, 2022 12.
Artículo en Inglés | MEDLINE | ID: mdl-36513472

RESUMEN

Aggressive nutrition therapy is a nutritional management method that sets energy intake requirements by adding the amount of energy accumulated to energy consumption. It is used to treat patients with undernutrition and sarcopenia. However, evidence for aggressive nutrition therapy is insufficient, and validation through high-quality clinical research is essential. Therefore, this paper aimed to clarify the concept of aggressive nutrition therapy, present indications and contraindications; and describe the effects, limitations, and the need to individualize aggressive nutrition therapy for different pathological conditions. Aggressive nutrition therapy should be accompanied by the etiology of undernutrition, sarcopenia, and nutritional metabolism in various states. In addition to calculating nutritional requirements, the nutritional management methods of oral intake, tube feeding, and parenteral nutrition should be appropriately selected. A nutrition plan with the amount of energy accumulated should also be a vital issue. This position paper was authored by the Registered Dietitian Subcommittee of the Japanese Association of Rehabilitation Nutrition and was approved by the Japanese Association of Rehabilitation Nutrition.


Asunto(s)
Desnutrición , Sarcopenia , Humanos , Sarcopenia/terapia , Apoyo Nutricional , Nutrición Enteral , Nutrición Parenteral/métodos , Desnutrición/prevención & control
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