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1.

Runx2 Regulates Galnt3 and Fgf23 Expressions and Galnt3 Decelerates Osteoid Mineralization by Stabilizing Fgf23.

Jiang, Qing; Qin, Xin; Moriishi, Takeshi; Fukuyama, Ryo; Katsumata, Shinichi; Matsuzaki, Hiroshi; Komori, Hisato; Matsuo, Yuki; Sakane, Chiharu; Ito, Kosei; Hojo, Hironori; Ohba, Shinsuke; Komori, Toshihisa.

Int J Mol Sci; 25(4)2024 Feb 14.

Artículo en Inglés | MEDLINE | ID: mdl-38396954

2.

Nupr1 deficiency downregulates HtrA1, enhances SMAD1 signaling, and suppresses age-related bone loss in male mice.

Murayama, Masatoshi; Hirata, Hirohito; Shiraki, Makoto; Iovanna, Juan L; Yamaza, Takayoshi; Kukita, Toshio; Komori, Toshihisa; Moriishi, Takeshi; Ueno, Masaya; Morimoto, Tadatsugu; Mawatari, Masaaki; Kukita, Akiko.

J Cell Physiol; 238(3): 566-581, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36715607

3.

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts.

Qin, Xin; Jiang, Qing; Nagano, Kenichi; Moriishi, Takeshi; Miyazaki, Toshihiro; Komori, Hisato; Ito, Kosei; Mark, Klaus von der; Sakane, Chiharu; Kaneko, Hitomi; Komori, Toshihisa.

PLoS Genet; 16(11): e1009169, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-33253203

4.

Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass.

Moriishi, Takeshi; Ozasa, Ryosuke; Ishimoto, Takuya; Nakano, Takayoshi; Hasegawa, Tomoka; Miyazaki, Toshihiro; Liu, Wenguang; Fukuyama, Ryo; Wang, Yuying; Komori, Hisato; Qin, Xin; Amizuka, Norio; Komori, Toshihisa.

PLoS Genet; 16(5): e1008586, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32463816

5.

Bcl2l1 Deficiency in Osteoblasts Reduces the Trabecular Bone Due to Enhanced Osteoclastogenesis Likely through Osteoblast Apoptosis.

Moriishi, Takeshi; Kawai, Yosuke; Fukuyama, Ryo; Matsuo, Yuki; He, You-Wen; Akiyama, Haruhiko; Asahina, Izumi; Komori, Toshihisa.

Int J Mol Sci; 24(24)2023 Dec 10.

Artículo en Inglés | MEDLINE | ID: mdl-38139148

6.

Whole Aspect of Runx2 Functions in Skeletal Development.

Komori, Toshihisa.

Int J Mol Sci; 23(10)2022 May 21.

Artículo en Inglés | MEDLINE | ID: mdl-35628587

7.

Osteocytes: Their Lacunocanalicular Structure and Mechanoresponses.

Moriishi, Takeshi; Komori, Toshihisa.

Int J Mol Sci; 23(8)2022 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-35457191

8.

Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs.

Jiang, Qing; Qin, Xin; Nagano, Kenichi; Komori, Hisato; Matsuo, Yuki; Taniuchi, Ichiro; Ito, Kosei; Komori, Toshihisa.

Int J Mol Sci; 23(21)2022 Oct 31.

Artículo en Inglés | MEDLINE | ID: mdl-36362086

9.

Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading.

Moriishi, Takeshi; Ito, Takuro; Fukuyama, Ryo; Qin, Xin; Komori, Hisato; Kaneko, Hitomi; Matsuo, Yuki; Yoshida, Noriaki; Komori, Toshihisa.

Int J Mol Sci; 23(6)2022 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-35328592

10.

Runx2 regulates cranial suture closure by inducing hedgehog, Fgf, Wnt and Pthlh signaling pathway gene expressions in suture mesenchymal cells.

Qin, Xin; Jiang, Qing; Miyazaki, Toshihiro; Komori, Toshihisa.

Hum Mol Genet; 28(6): 896-911, 2019 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-30445456

11.

Functions of Osteocalcin in Bone, Pancreas, Testis, and Muscle.

Komori, Toshihisa.

Int J Mol Sci; 21(20)2020 Oct 12.

Artículo en Inglés | MEDLINE | ID: mdl-33053789

12.

Molecular Processes in Chondrocyte Biology.

Komori, Toshihisa.

Int J Mol Sci; 21(11)2020 Jun 11.

Artículo en Inglés | MEDLINE | ID: mdl-32545161

13.

Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice.

Matsuura, Viviane K S Kawata; Yoshida, Carolina Andrea; Komori, Hisato; Sakane, Chiharu; Yamana, Kei; Jiang, Qing; Komori, Toshihisa.

Int J Mol Sci; 21(8)2020 Apr 12.

Artículo en Inglés | MEDLINE | ID: mdl-32290615

14.

Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis.

Jiang, Qing; Qin, Xin; Yoshida, Carolina Andrea; Komori, Hisato; Yamana, Kei; Ohba, Shinsuke; Hojo, Hironori; Croix, Brad St; Kawata-Matsuura, Viviane K S; Komori, Toshihisa.

Int J Mol Sci; 21(7)2020 Mar 31.

Artículo en Inglés | MEDLINE | ID: mdl-32244499

15.

Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2.

Komori, Toshihisa.

Int J Mol Sci; 20(7)2019 Apr 04.

Artículo en Inglés | MEDLINE | ID: mdl-30987410

16.

Runx2, an inducer of osteoblast and chondrocyte differentiation.

Komori, Toshihisa.

Histochem Cell Biol; 149(4): 313-323, 2018 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-29356961

17.

Lack of reproducibility in osteocalcin-deficient mice.

Moriishi, Takeshi; Komori, Toshihisa.

PLoS Genet; 16(6): e1008939, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32589663

18.

Influenza A Virus-Induced Expression of a GalNAc Transferase, GALNT3, via MicroRNAs Is Required for Enhanced Viral Replication.

Nakamura, Shoko; Horie, Masayuki; Daidoji, Tomo; Honda, Tomoyuki; Yasugi, Mayo; Kuno, Atsushi; Komori, Toshihisa; Okuzaki, Daisuke; Narimatsu, Hisashi; Nakaya, Takaaki; Tomonaga, Keizo.

J Virol; 90(4): 1788-801, 2016 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-26637460

19.

Immunohistochemical analysis of dentin matrix protein 1 (Dmp1) phosphorylation by Fam20C in bone: implications for the induction of biomineralization.

Oya, Kaori; Ishida, Ken; Nishida, Tomoki; Sato, Sunao; Kishino, Mitsunobu; Hirose, Katsutoshi; Ogawa, Yuzo; Ikebe, Kazunori; Takeshige, Fumio; Yasuda, Hidehiro; Komori, Toshihisa; Toyosawa, Satoru.

Histochem Cell Biol; 147(3): 341-351, 2017 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-27614627

20.

Roles of Runx2 in Skeletal Development.

Komori, Toshihisa.

Adv Exp Med Biol; 962: 83-93, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-28299652

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Runx2 Regulates Galnt3 and Fgf23 Expressions and Galnt3 Decelerates Osteoid Mineralization by Stabilizing Fgf23.

Nupr1 deficiency downregulates HtrA1, enhances SMAD1 signaling, and suppresses age-related bone loss in male mice.

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts.

Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass.

Bcl2l1 Deficiency in Osteoblasts Reduces the Trabecular Bone Due to Enhanced Osteoclastogenesis Likely through Osteoblast Apoptosis.

Whole Aspect of Runx2 Functions in Skeletal Development.

Osteocytes: Their Lacunocanalicular Structure and Mechanoresponses.

Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs.

Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading.

Runx2 regulates cranial suture closure by inducing hedgehog, Fgf, Wnt and Pthlh signaling pathway gene expressions in suture mesenchymal cells.

Functions of Osteocalcin in Bone, Pancreas, Testis, and Muscle.

Molecular Processes in Chondrocyte Biology.

Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice.

Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis.

Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2.

Runx2, an inducer of osteoblast and chondrocyte differentiation.

Lack of reproducibility in osteocalcin-deficient mice.

Influenza A Virus-Induced Expression of a GalNAc Transferase, GALNT3, via MicroRNAs Is Required for Enhanced Viral Replication.

Immunohistochemical analysis of dentin matrix protein 1 (Dmp1) phosphorylation by Fam20C in bone: implications for the induction of biomineralization.

Roles of Runx2 in Skeletal Development.