Detalles de la búsqueda
1.
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Nature;
552(7684): 194-199, 2017 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29211715
2.
Improving the efficacy of proteasome inhibitors in the treatment of renal cell carcinoma by combination with the human immunodeficiency virus (HIV)-protease inhibitors lopinavir or nelfinavir.
BJU Int;
121(4): 600-609, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29161753
3.
Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08).
Haematologica;
101(3): 346-55, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26659919
4.
A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities.
Angew Chem Int Ed Engl;
55(13): 4199-203, 2016 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26511210
5.
The novel ß2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells.
Haematologica;
100(10): 1350-60, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26069288
6.
A metabolic switch in proteasome inhibitor-resistant multiple myeloma ensures higher mitochondrial metabolism, protein folding and sphingomyelin synthesis.
Haematologica;
104(9): e415-e419, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30792209
7.
The cytotoxic activity of carfilzomib together with nelfinavir is superior to the bortezomib/nelfinavir combination in non-small cell lung carcinoma.
Sci Rep;
13(1): 4411, 2023 03 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36932175
8.
Immunoproteasome Activity in Chronic Lymphocytic Leukemia as a Target of the Immunoproteasome-Selective Inhibitors.
Cells;
11(5)2022 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35269460
9.
HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase.
Blood;
114(1): 85-94, 2009 Jul 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-19436054
10.
Novel Peptide-drug Conjugate Melflufen Efficiently Eradicates Bortezomib-resistant Multiple Myeloma Cells Including Tumor-initiating Myeloma Progenitor Cells.
Hemasphere;
5(7): e602, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-34136753
11.
High Immunoproteasome Activity and sXBP1 in Pediatric Precursor B-ALL Predicts Sensitivity towards Proteasome Inhibitors.
Cells;
10(11)2021 10 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34831075
12.
Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines.
Chembiochem;
10(16): 2638-43, 2009 Nov 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-19746508
13.
Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis.
Mol Cancer Ther;
7(7): 1940-8, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18645004
14.
Novel cell line models to study mechanisms and overcoming strategies of proteasome inhibitor resistance in multiple myeloma.
Biochim Biophys Acta Mol Basis Dis;
1865(6): 1666-1676, 2019 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30954557
15.
Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors.
Cell Chem Biol;
26(3): 340-351.e3, 2019 03 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-30612952
16.
Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins.
J Leukoc Biol;
81(4): 990-1001, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17261546
17.
The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma.
Mol Cancer Ther;
16(11): 2375-2386, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28878026
18.
Up-regulation of multidrug resistance protein MDR1/ABCB1 in carfilzomib-resistant multiple myeloma differentially affects efficacy of anti-myeloma drugs.
Leuk Res;
101: 106499, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33422770
19.
Probing the potential of platinum(II) complexes for the inhibition of thiol-dependent enzymatic activity.
J Inorg Biochem;
99(6): 1384-9, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15869797
20.
Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner.
J Leukoc Biol;
75(5): 844-55, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-14966190