RESUMEN
To our knowledge, this is the first clinical report of a rofecoxib-associated upper gastrointestinal hemorrhage. We urge caution in prescribing rofecoxib to patients with risk factors for peptic ulcer disease and recommend limiting the dose to 25 mg per day for these patients.
Asunto(s)
Antiinflamatorios no Esteroideos/efectos adversos , Hemorragia Gastrointestinal/inducido químicamente , Lactonas/efectos adversos , Artritis Reumatoide/complicaciones , Artritis Reumatoide/tratamiento farmacológico , Enfermedad de Crohn/complicaciones , Humanos , Masculino , Persona de Mediana Edad , Úlcera Péptica/complicaciones , SulfonasRESUMEN
A case of a 16-year-old with herpes simplex virus type-1 infection with radicular arm pain is reported. The clinical implications of the case are discussed.
Asunto(s)
Herpes Simple/complicaciones , Radiculopatía/virología , Adolescente , Brazo , Vértebras Cervicales , Humanos , Masculino , Radiculopatía/diagnóstico , Radiculopatía/tratamiento farmacológicoRESUMEN
The purpose of this study was to determine if preemptive epidural analgesia performed before thoracotomy incision and during the operation reduces postoperative pain. Patients in the treatment group received 8 mL of 0.25% bupivacaine and 2 mL of fentanyl (50 microg/mL) via the epidural route prior to skin incision, followed by an infusion of bupivacaine 0.1% and fentanyl 10 microg/mL at 6 mL/hr. The control group received saline in the epidural. All patients in both groups were dosed with 8 mL of 0.25% bupivacaine and 2 mL of fentanyl 50 microg/mL via the epidural route at the time of the chest closure. The patients in the treatment group required less isoflurane intraoperatively and had lower maximum pain scores in the first 6 hours postoperatively. No significant differences were noted after the first 6 hours.