Analysis of ortho-phthalates and other plasticizers in select organic and conventional foods in the United States.

BACKGROUND: ortho-phthalates and other plasticizers impart flexibility to plastics in food production, processing, and packaging; food consumption is a dominant plasticizer exposure pathway. Lower molecular weight ortho-phthalates are being replaced in plastic products due to toxicity concerns, but toxic hazards of and exposures to replacement ortho-phthalates and other plasticizers are poorly understood. OBJECTIVE: We measured 12 ortho-phthalates and 9 other plasticizers in conventional and organic U.S. food products to assess magnitude and profiles of contamination. METHODS: We measured plasticizers in 34 vegetable oils, 10 milks, 18 infant formulas, and 9 cheese powders from macaroni kits using gas chromatography coupled with mass spectrometry (GC-MS). We analyzed plastic packaging composition using FTIR spectroscopy. RESULTS: We detected eight ortho-phthalates and three alternatives ((1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH), diethylhexyl terephthalate (DEHT), and diisobutyl adipate (DIBA). Diethylhexyl phthalate (DEHP) was measured in all 71 products. DEHT had the highest concentration of any plasticizer (>10,000 ng/g in three oils). Oils had the highest total plasticizer (median = 770 ng/g, max = 14,900 ng/g) and milk the lowest (median = 88 ng/g, max = 120 ng/g). Organic milk and refined oils had higher median plasticizer levels than conventional. Refined oils had significantly lower concentrations than unrefined oils. Maximum contributors for every category were non-ortho-phthalates: DEHT (powdered infant formula and oils) and DIBA (cheese powder, milk and liquid formula). Plasticizers were not detected in packaging except epoxidized soybean oil in liquid formula lids. IMPACT STATEMENT: Human exposure to plasticizers is a significant public health concern. Nevertheless, sources of such exposures are poorly characterized. This study adds valuable information for estimating legacy and alternative plasticizer exposures from foods. The method developed for measuring DINCH, DINP and DIDP broadens the range of plasticizers other researchers may analyze in future work. The profiles of plasticizer contamination varied depending on the food type. We also document that food processing may be a source of plasticizer contamination in foods.

Investigation of distribution, sources and flux of perfluorinated compounds in major southern Indian rivers and their risk assessment.

Perfluorinated compounds (PFCs) are a group of emerging contaminants still less reported in rivers, particularly southern India. Therefore, we investigated the fate of 13 PFCs in three major rivers in southern India during post-monsoon and summer seasons. Twelve PFCs were detected, with an average total PFCs of 1853 ± 1463 pg/l. However, the total PFCs recorded in ppost-monsoon and summer seasons ranged from ND (none detected) to 10,545 pg/l and ND to 4960 pg/l, respectively. Among the individual congeners, perfluoro-n-hexanoic acid (PFHxA) had the highest detection average (929 ± 710 pg/l). The higher detection of short chain PFCs signifies their increasing wide usage as an alternative to perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS). Higher levels of PFCs were observed in summer than post-monsoon season in the river Kaveri, which is mainly attributed to the decrease in river flow. A multidimensional source identification revealed domestic and commercial wastewater as the major source. A correlation analysis showed that most of the detected PFCs share the common source and undergo co-migration into rivers. The flux of PFCs into the Bay of Bengal, loaded by the Kaveri (15 kg/yr) and the Tamiraparani (2.2 kg/yr) rivers, signifies lower per capita emissions than other rivers in India and other countries. Further, the PFC levels found in the rivers can be considered safe for human consumption and aquatic organisms based on international guidelines. Being the first hand report in southern Indian rivers, the results warrant further investigation to understand the exact sources, fate and removal in detail.