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1.
Protective roles of adropin in neurological disease.
Am J Physiol Cell Physiol;
324(3): C674-C678, 2023 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36717106
2.
Therapeutic Benefits of Adropin in Aged Mice After Transient Ischemic Stroke via Reduction of Blood-Brain Barrier Damage.
Stroke;
54(1): 234-244, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36305313
3.
Receptor-interacting protein kinase 2 (RIPK2) profoundly contributes to post-stroke neuroinflammation and behavioral deficits with microglia as unique perpetrators.
J Neuroinflammation;
20(1): 221, 2023 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37777791
4.
An Unexplored Role for MMP-7 (Matrix Metalloproteinase-7) in Promoting Gut Permeability After Ischemic Stroke.
Stroke;
53(10): 3238-3242, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35904018
5.
Targeted BRD4 protein degradation by dBET1 ameliorates acute ischemic brain injury and improves functional outcomes associated with reduced neuroinflammation and oxidative stress and preservation of blood-brain barrier integrity.
J Neuroinflammation;
19(1): 168, 2022 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35761277
6.
HOPS-dependent endosomal fusion required for efficient cytosolic delivery of therapeutic peptides and small proteins.
Proc Natl Acad Sci U S A;
116(2): 512-521, 2019 01 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30610181
7.
Unique arginine array improves cytosolic localization of hydrocarbon-stapled peptides.
Bioorg Med Chem;
26(6): 1197-1202, 2018 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29150077
8.
Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2.
Bioorg Med Chem;
25(24): 6479-6485, 2017 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29089257
9.
Structural and Functional Consequences of Three Cancer-Associated Mutations of the Oncogenic Phosphatase SHP2.
Biochemistry;
55(15): 2269-77, 2016 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27030275
10.
Fluorescence correlation spectroscopy reveals highly efficient cytosolic delivery of certain penta-arg proteins and stapled peptides.
J Am Chem Soc;
137(7): 2536-2541, 2015 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-25679876
11.
Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo.
J Am Chem Soc;
137(44): 14084-93, 2015 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26465072
12.
Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery.
Biochemistry;
53(24): 4034-46, 2014 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24896852
13.
Pharmacological inhibition of receptor-interacting protein kinase 2 (RIPK2) elicits neuroprotective effects following experimental ischemic stroke.
Exp Neurol;
377: 114812, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38729551
14.
Functional regulation of microglia by vitamin B12 alleviates ischemic stroke-induced neuroinflammation in mice.
iScience;
27(4): 109480, 2024 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38715940
15.
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Cancer Discov;
14(2): 240-257, 2024 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37916956
16.
Improved assays for determining the cytosolic access of peptides, proteins, and their mimetics.
Biochemistry;
52(50): 9036-46, 2013 Dec 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24256505
17.
Neuroprotection by the cannabidiol aminoquinone VCE-004.8 in experimental ischemic stroke in mice.
Neurochem Int;
165: 105508, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36863495
18.
Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling.
Elife;
102021 03 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33755016
19.
Neurovascular protection by adropin in experimental ischemic stroke through an endothelial nitric oxide synthase-dependent mechanism.
Redox Biol;
48: 102197, 2021 Nov 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34826783
20.
Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition.
Nat Commun;
9(1): 4508, 2018 10 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-30375388