Detalles de la búsqueda
1.
Impact of renal impairment and human organic anion transporter inhibition on pharmacokinetics, safety and tolerability of relebactam combined with imipenem and cilastatin.
Br J Clin Pharmacol;
86(5): 944-957, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31856304
2.
Pharmacokinetics and pharmacodynamics of single and multiple doses of the glucagon receptor antagonist LGD-6972 in healthy subjects and subjects with type 2 diabetes mellitus.
Diabetes Obes Metab;
19(1): 24-32, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27501510
3.
Pharmacokinetics of sugammadex in subjects with moderate and severe renal impairmentâ©.
Int J Clin Pharmacol Ther;
55(9): 746-752, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28679468
4.
Relative Bioavailabilities of Lisdexamfetamine Dimesylate and D-Amphetamine in Healthy Adults in an Open-Label, Randomized, Crossover Study After Mixing Lisdexamfetamine Dimesylate With Food or Drink.
Ther Drug Monit;
38(6): 769-776, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27661399
5.
A Single-Dose, Open-Label Study of the Pharmacokinetics, Safety, and Tolerability of Lisdexamfetamine Dimesylate in Individuals With Normal and Impaired Renal Function.
Ther Drug Monit;
38(4): 546-55, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26926668
6.
Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics--results from single oral dose studies in healthy volunteers.
Br J Clin Pharmacol;
75(5): 1240-54, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23013236
7.
Effects of Renal Impairment on the Pharmacokinetics of Gefapixant, a P2X3 Receptor Antagonist.
J Clin Pharmacol;
62(11): 1435-1444, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35656754
8.
Effect of Mild and Moderate Hepatic Impairment (Defined by Child-Pugh Classification and National Cancer Institute Organ Dysfunction Working Group Criteria) on Pexidartinib Pharmacokinetics.
J Clin Pharmacol;
62(8): 992-1005, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35247274
9.
A Microdose Cocktail to Evaluate Drug Interactions in Patients with Renal Impairment.
Clin Pharmacol Ther;
109(2): 403-415, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32705692
10.
Pharmacokinetics and Safety of the Novel Selective Progesterone Receptor Modulator Vilaprisan in Participants With Renal Impairment.
J Clin Pharmacol;
60(8): 1030-1038, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32227643
11.
Effects of Maribavir on P-Glycoprotein and CYP2D6 in Healthy Volunteers.
J Clin Pharmacol;
60(1): 96-106, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31385617
12.
Lack of a clinically important effect of moderate hepatic insufficiency and severe renal insufficiency on raltegravir pharmacokinetics.
Antimicrob Agents Chemother;
53(5): 1747-52, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19223645
13.
Ketoconazole increases fingolimod blood levels in a drug interaction via CYP4F2 inhibition.
J Clin Pharmacol;
49(2): 212-8, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19118083
14.
Influence of taranabant, an orally active, highly selective, potent cannabinoid-1 receptor (CB1R) inverse agonist, on ethinyl estradiol and norelgestromin plasma pharmacokinetics.
J Clin Pharmacol;
49(1): 72-9, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18936284
15.
Single-dose pharmacokinetics and pharmacodynamics of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects.
Br J Clin Pharmacol;
68(4): 535-45, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19843057
16.
Influence of laropiprant, a selective prostaglandin D2 receptor 1 antagonist, on the pharmacokinetics and pharmacodynamics of warfarin.
Am J Ther;
16(3): 215-23, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19454860
17.
Single-Dose Pharmacokinetics and Safety of Solriamfetol in Participants With Normal or Impaired Renal Function and With End-Stage Renal Disease Requiring Hemodialysis.
J Clin Pharmacol;
59(8): 1120-1129, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30865315
18.
Lack of a significant drug interaction between raltegravir and tenofovir.
Antimicrob Agents Chemother;
52(9): 3253-8, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-18625763
19.
Ghrelin agonist (TZP-101): safety, pharmacokinetics and pharmacodynamic evaluation in healthy volunteers: a phase I, first-in-human study.
J Clin Pharmacol;
48(2): 193-202, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18199894
20.
Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood pressure in nondiabetic patients with mild to moderate hypertension.
J Clin Pharmacol;
48(5): 592-8, 2008 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-18353996