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1.

Translocated microbiome composition determines immunological outcome in treated HIV infection.

Nganou-Makamdop, Krystelle; Talla, Aarthi; Sharma, Ashish Arunkumar; Darko, Sam; Ransier, Amy; Laboune, Farida; Chipman, Jeffrey G; Beilman, Gregory J; Hoskuldsson, Torfi; Fourati, Slim; Schmidt, Thomas E; Arumugam, Sahaana; Lima, Noemia S; Moon, Damee; Callisto, Samuel; Schoephoerster, Jordan; Tomalka, Jeffery; Mugyenyi, Peter; Ssali, Francis; Muloma, Proscovia; Ssengendo, Patrick; Leda, Ana R; Cheu, Ryan K; Flynn, Jacob K; Morou, Antigoni; Brunet-Ratnasingham, Elsa; Rodriguez, Benigno; Lederman, Michael M; Kaufmann, Daniel E; Klatt, Nichole R; Kityo, Cissy; Brenchley, Jason M; Schacker, Timothy W; Sekaly, Rafick P; Douek, Daniel C.

Cell; 184(15): 3899-3914.e16, 2021 07 22.

Artículo en Inglés | MEDLINE | ID: mdl-34237254

2.

Cytomegalovirus Infection Facilitates the Costimulation of CD57+CD28- CD8 T Cells in HIV Infection and Atherosclerosis via the CD2-LFA-3 Axis.

Winchester, Nicole E; Panigrahi, Soumya; Haria, Anokhi; Chakraborty, Archeesha; Su, Xi; Chen, Bonnie; Morris, Stephen R; Clagett, Brian M; Juchnowski, Steven M; Yadavalli, Raghavendra; Villinger, Francois; Paiardini, Mirko; Harth, Karem; Kashyap, Vikram S; Calabrese, Leonard H; Margolis, Leonid; Sieg, Scott F; Shive, Carey L; Gianella, Sara; Funderburg, Nicholas T; Zidar, David A; Lederman, Michael M; Freeman, Michael L.

J Immunol; 212(2): 245-257, 2024 01 15.

Artículo en Inglés | MEDLINE | ID: mdl-38047900

3.

HIV post-treatment controllers have distinct immunological and virological features.

Etemad, Behzad; Sun, Xiaoming; Li, Yijia; Melberg, Meghan; Moisi, Daniela; Gottlieb, Rachel; Ahmed, Hayat; Aga, Evgenia; Bosch, Ronald J; Acosta, Edward P; Yuki, Yuko; Martin, Maureen P; Carrington, Mary; Gandhi, Rajesh T; Jacobson, Jeffrey M; Volberding, Paul; Connick, Elizabeth; Mitsuyasu, Ronald; Frank, Ian; Saag, Michael; Eron, Joseph J; Skiest, Daniel; Margolis, David M; Havlir, Diane; Schooley, Robert T; Lederman, Michael M; Yu, Xu G; Li, Jonathan Z.

Proc Natl Acad Sci U S A; 120(11): e2218960120, 2023 03 14.

Artículo en Inglés | MEDLINE | ID: mdl-36877848

4.

Effect of Immune-Modulatory Interventions on Asymptomatic Cytomegalovirus Shedding During Suppressive Antiretroviral Therapy.

Hastie, Elizabeth; Moser, Carlee; Sun, Xin; Lennox, Jeffrey; Hsue, Priscilla Y; Bosch, Ronald J; Deeks, Steven; Meneses, Milenka V; Lederman, Michael M; Hunt, Peter; Henrich, Timothy J; Marconi, Vincent C; Gianella, Sara.

J Infect Dis; 228(1): 64-69, 2023 06 28.

Artículo en Inglés | MEDLINE | ID: mdl-36881933

5.

Interleukin 18 (IL-18) and IL-3 in Extracellular Vesicles: Biomarkers for Durable Elite Control of HIV-1.

Poveda, Eva; Fitzgerald, Wendy; Reglero, Cristina; Pérez-González, Alexandre; Mariño, Ana; Álvarez, Hortensia; Valcarce, Nieves; Llibre, Josep Maria; Guillén, Santiago Moreno; Muñoz Fernández, Maria Angeles; Ruiz-Mateos, Ezequiel; Margolis, Leonid; Lederman, Michael M; Freeman, Michael L.

J Infect Dis; 227(12): 1381-1385, 2023 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-36790818

6.

Interleukin 6 Blockade With Tocilizumab Diminishes Indices of Inflammation That Are Linked to Mortality in Treated Human Immunodeficiency Virus Infection.

Funderburg, Nicholas T; Shive, Carey L; Chen, Zhengyi; Tatsuoka, Curtis; Bowman, Emily R; Longenecker, Chris T; McComsey, Grace A; Clagett, Brian M; Dorazio, Dominic; Freeman, Michael L; Sieg, Scott F; Moisi, Daniela; Anthony, Donald D; Jacobson, Jeffrey M; Stein, Sharon L; Calabrese, Leonard H; Landay, Alan; Flexner, Charles; Crawford, Keith W; Capparelli, Edmund V; Rodriguez, Benigno; Lederman, Michael M.

Clin Infect Dis; 77(2): 272-279, 2023 07 26.

Artículo en Inglés | MEDLINE | ID: mdl-37011013

7.

'Rinse and Replace': Boosting T Cell Turnover To Reduce HIV-1 Reservoirs.

Grossman, Zvi; Singh, Nevil J; Simonetti, Francesco R; Lederman, Michael M; Douek, Daniel C; Deeks, Steven G.

Trends Immunol; 41(6): 466-480, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32414695

8.

Massive Release of CD9+ Microvesicles in Human Immunodeficiency Virus Infection, Regardless of Virologic Control.

Poveda, Eva; Tabernilla, Andrés; Fitzgerald, Wendy; Salgado-Barreira, Ángel; Grandal, Marta; Pérez, Alexandre; Mariño, Ana; Álvarez, Hortensia; Valcarce, Nieves; González-García, Juan; Bernardino, José Ignacio; Gutierrez, Félix; Fujioka, Hisashi; Crespo, Manuel; Ruiz-Mateos, Ezequiel; Margolis, Leonid; Lederman, Michael M; Freeman, Michael L.

J Infect Dis; 225(6): 1040-1049, 2022 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-32603406

9.

Randomized Trial of Ruxolitinib in Antiretroviral-Treated Adults With Human Immunodeficiency Virus.

Marconi, Vincent C; Moser, Carlee; Gavegnano, Christina; Deeks, Steven G; Lederman, Michael M; Overton, Edgar T; Tsibris, Athe; Hunt, Peter W; Kantor, Amy; Sekaly, Rafick-Pierre; Tressler, Randall; Flexner, Charles; Hurwitz, Selwyn J; Moisi, Daniela; Clagett, Brian; Hardin, William R; Del Rio, Carlos; Schinazi, Raymond F; Lennox, Jeffrey J.

Clin Infect Dis; 74(1): 95-104, 2022 01 07.

Artículo en Inglés | MEDLINE | ID: mdl-33693561

10.

Driving T cells to human atherosclerotic plaques: CCL3/CCR5 and CX3CL1/CX3CR1 migration axes.

Komissarov, Alexey; Potashnikova, Daria; Freeman, Michael L; Gontarenko, Vladimir; Maytesyan, Derenik; Lederman, Michael M; Vasilieva, Elena; Margolis, Leonid.

Eur J Immunol; 51(7): 1857-1859, 2021 07.

Artículo en Inglés | MEDLINE | ID: mdl-33772780

11.

Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms.

Bowman, Emily R; Cameron, Cheryl M; Richardson, Brian; Kulkarni, Manjusha; Gabriel, Janelle; Cichon, Morgan J; Riedl, Kenneth M; Mustafa, Yousef; Cartwright, Michael; Snyder, Brandon; Raman, Subha V; Zidar, David A; Koletar, Susan L; Playford, Martin P; Mehta, Nehal N; Sieg, Scott F; Freeman, Michael L; Lederman, Michael M; Cameron, Mark J; Funderburg, Nicholas T.

PLoS Pathog; 16(10): e1008869, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-33002093

12.

CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis.

Panigrahi, Soumya; Chen, Bonnie; Fang, Mike; Potashnikova, Daria; Komissarov, Alexey A; Lebedeva, Anna; Michaelson, Gillian M; Wyrick, Jonathan M; Morris, Stephen R; Sieg, Scott F; Paiardini, Mirko; Villinger, Francois J; Harth, Karem; Kashyap, Vikram S; Cameron, Mark J; Cameron, Cheryl M; Vasilieva, Elena; Margolis, Leonid; Younes, Souheil-Antoine; Funderburg, Nicholas T; Zidar, David A; Lederman, Michael M; Freeman, Michael L.

PLoS Pathog; 16(9): e1008885, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32976527

13.

A surprising role for TLR7.

Lederman, Michael M.

Nat Immunol; 16(1): 8-9, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25521672

14.

Cytomegalovirus Coinfection Is Associated with Increased Vascular-Homing CD57⁺ CD4 T Cells in HIV Infection.

Chen, Bonnie; Morris, Stephen R; Panigrahi, Soumya; Michaelson, Gillian M; Wyrick, Jonathan M; Komissarov, Alexey A; Potashnikova, Daria; Lebedeva, Anna; Younes, Souheil-Antoine; Harth, Karem; Kashyap, Vikram S; Vasilieva, Elena; Margolis, Leonid; Zidar, David A; Sieg, Scott F; Shive, Carey L; Funderburg, Nicholas T; Gianella, Sara; Lederman, Michael M; Freeman, Michael L.

J Immunol; 204(10): 2722-2733, 2020 05 15.

Artículo en Inglés | MEDLINE | ID: mdl-32229536

15.

Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence.

Pino, Maria; Paganini, Sara; Deleage, Claire; Padhan, Kartika; Harper, Justin L; King, Colin T; Micci, Luca; Cervasi, Barbara; Mudd, Joseph C; Gill, Kiran P; Jean, Sherrie M; Easley, Kirk; Silvestri, Guido; Estes, Jacob D; Petrovas, Constantinos; Lederman, Michael M; Paiardini, Mirko.

PLoS Pathog; 15(10): e1008081, 2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-31626660

16.

Highly oxidized low-density lipoprotein mediates activation of monocytes but does not confer interleukin-1ß secretion nor interleukin-15 transpresentation function.

Sieg, Scott F; Bazdar, Douglas A; Zidar, David; Freeman, Michael; Lederman, Michael M; Funderburg, Nicholas T.

Immunology; 159(2): 221-230, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31663113

17.

In Vitro Exposure of Leukocytes to HIV Preexposure Prophylaxis Decreases Mitochondrial Function and Alters Gene Expression Profiles.

Bowman, Emily R; Cameron, Cheryl; Richardson, Brian; Kulkarni, Manjusha; Gabriel, Janelle; Kettelhut, Aaren; Hornsby, Lane; Kwiek, Jesse J; Turner, Abigail Norris; Malvestutto, Carlos; Bazan, Jose; Koletar, Susan L; Doblecki-Lewis, Susanne; Lederman, Michael M; Cameron, Mark; Klatt, Nichole R; Lake, Jordan E; Funderburg, Nicholas T.

Antimicrob Agents Chemother; 65(1)2020 12 16.

Artículo en Inglés | MEDLINE | ID: mdl-33020165

18.

Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy.

Wang, Chao; Edilova, Maria I; Wagar, Lisa E; Mujib, Shariq; Singer, Meromit; Bernard, Nicole F; Croughs, Thérèse; Lederman, Michael M; Sereti, Irini; Fischl, Margaret A; Kremmer, Elisabeth; Ostrowski, Mario; Routy, Jean-Pierre; Watts, Tania H.

J Immunol; 200(2): 558-564, 2018 01 15.

Artículo en Inglés | MEDLINE | ID: mdl-29222166

19.

CD8+ T-Cell-Derived Tumor Necrosis Factor Can Induce Tissue Factor Expression on Monocytes.

Freeman, Michael L; Panigrahi, Soumya; Chen, Bonnie; Juchnowski, Steven; Sieg, Scott F; Lederman, Michael M; Funderburg, Nicholas T; Zidar, David A.

J Infect Dis; 220(1): 73-77, 2019 06 05.

Artículo en Inglés | MEDLINE | ID: mdl-30698729

20.

Soluble Urokinase Plasminogen Activator Receptor Is Predictive of Non-AIDS Events During Antiretroviral Therapy-mediated Viral Suppression.

Hoenigl, Martin; Moser, Carlee B; Funderburg, Nicholas; Bosch, Ronald; Kantor, Amy; Zhang, Yonglong; Eugen-Olsen, Jesper; Finkelman, Malcolm; Reiser, Jochen; Landay, Alan; Moisi, Daniela; Lederman, Michael M; Gianella, Sara.

Clin Infect Dis; 69(4): 676-686, 2019 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-30418519

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