Detalles de la búsqueda
1.
Discovery of (E)-2-(hydroxyimino)-N-(2 ((4methylpentyl)amino)ethyl)acetamide (KR-27425) as a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase.
Bioorg Med Chem Lett;
96: 129504, 2023 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37838342
2.
Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse model.
Bioorg Chem;
127: 105923, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35717803
3.
Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity.
Cell Mol Life Sci;
78(1): 207-225, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-32140747
4.
Radicicol Inhibits Chikungunya Virus Replication by Targeting Nonstructural Protein 2.
Antimicrob Agents Chemother;
65(7): e0013521, 2021 06 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33903104
5.
Identification of non-covalent 3C-like protease inhibitors against severe acute respiratory syndrome coronavirus-2 via virtual screening of a Korean compound library.
Bioorg Med Chem Lett;
42: 128067, 2021 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33957246
6.
Synthesis of novel 1H-Pyrazolo[3,4-b]pyridine derivatives as DYRK 1A/1B inhibitors.
Bioorg Med Chem Lett;
47: 128226, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34182093
7.
Current Progress in the Development of Hepatitis B Virus Capsid Assembly Modulators: Chemical Structure, Mode-of-Action and Efficacy.
Molecules;
26(24)2021 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34946502
8.
Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research.
Molecules;
26(6)2021 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33802888
9.
Verification of the Necessity of the Tolyl Group of PF-543 for Sphingosine Kinase 1 Inhibitory Activity.
Molecules;
25(11)2020 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32471162
10.
Synthesis and Biological Evaluation of PF-543 Derivative Containing Aliphatic Side Chain.
Chem Pharm Bull (Tokyo);
67(6): 599-603, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31155566
11.
Apolipoprotein B binds to enolase-1 and aggravates inflammation in rheumatoid arthritis.
Ann Rheum Dis;
77(10): 1480-1489, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29997113
12.
Identification of quinone analogues as potential inhibitors of picornavirus 3C protease in vitro.
Bioorg Med Chem Lett;
28(14): 2533-2538, 2018 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29866517
13.
Synthesis and Biological Evaluation of FTY720 (Fingolimod) Derivatives with Aromatic Head Group as Anticancer Agents.
Chem Pharm Bull (Tokyo);
66(10): 1015-1018, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30270236
14.
Synthesis of Novel FTY720 Analogs with Anticancer Activity through PP2A Activation.
Molecules;
23(11)2018 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-30355990
15.
Synthesis and biological evaluation of N9-cis-cyclobutylpurine derivatives for use as cyclin-dependent kinase (CDK) inhibitors.
Bioorg Med Chem Lett;
27(18): 4399-4404, 2017 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28827110
16.
Serum levels of IgG antibodies against alpha-enolase are increased in patients with Behçet's disease and are associated with the severity of oral ulcer, erythrocyte sedimentation rates, and C-reactive protein.
Clin Exp Rheumatol;
35 Suppl 108(6): 67-74, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28770703
17.
Synthesis and Molecular Modeling Studies of N'-Hydroxyindazolecarboximidamides as Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
Molecules;
22(11)2017 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29120388
18.
Identification of a New Morpholine Scaffold as a P2Y12 Receptor Antagonist.
Molecules;
21(9)2016 Aug 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-27563870
19.
Design and synthesis of novel 2-(indol-5-yl)thiazole derivatives as xanthine oxidase inhibitors.
Bioorg Med Chem Lett;
25(6): 1254-8, 2015 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25704891
20.
Synthesis and biological evaluation of carbocyclic analogues of pachastrissamine.
Mar Drugs;
13(2): 824-37, 2015 Feb 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25654428