Detalles de la búsqueda
1.
Oral Dosing of Dihydromethysticin Ahead of Tobacco Carcinogen NNK Effectively Prevents Lung Tumorigenesis in A/J Mice.
Chem Res Toxicol;
33(7): 1980-1988, 2020 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32476407
2.
Gene expression signatures associated with suppression of TRAMP prostate carcinogenesis by a kavalactone-rich Kava fraction.
Mol Carcinog;
55(12): 2291-2303, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-26840761
3.
Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification.
Drug Metab Dispos;
44(3): 422-7, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26744252
4.
Dihydromethysticin (DHM) Blocks Tobacco Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-Induced O6-Methylguanine in a Manner Independent of the Aryl Hydrocarbon Receptor (AhR) Pathway in C57BL/6 Female Mice.
Chem Res Toxicol;
29(11): 1828-1834, 2016 11 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-27728767
5.
Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice.
Carcinogenesis;
35(10): 2365-72, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25053626
6.
Flavokawains a and B in kava, not dihydromethysticin, potentiate acetaminophen-induced hepatotoxicity in C57BL/6 mice.
Chem Res Toxicol;
27(10): 1871-6, 2014 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25185080
7.
Pilot in Vivo Structure-Activity Relationship of Dihydromethysticin in Blocking 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced O6-Methylguanine and Lung Tumor in A/J Mice.
J Med Chem;
60(18): 7935-7940, 2017 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-28806079
8.
Kava blocks 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in association with reducing O6-methylguanine DNA adduct in A/J mice.
Cancer Prev Res (Phila);
7(1): 86-96, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24403291
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