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1.

Fine-Tuning Cytokine Signals.

Lin, Jian-Xin; Leonard, Warren J.

Annu Rev Immunol; 37: 295-324, 2019 04 26.

Artículo en Inglés | MEDLINE | ID: mdl-30649989

2.

Transcription factor EGR2 controls homing and pathogenicity of T_H17 cells in the central nervous system.

Gao, Yuanyuan; Wang, Yan; Chauss, Daniel; Villarino, Alejandro V; Link, Verena M; Nagashima, Hiroyuki; Spinner, Camille A; Koparde, Vishal N; Bouladoux, Nicolas; Abers, Michael S; Break, Timothy J; Chopp, Laura B; Park, Jung-Hyun; Zhu, Jinfang; Wiest, David L; Leonard, Warren J; Lionakis, Michail S; O'Shea, John J; Afzali, Behdad; Belkaid, Yasmine; Lazarevic, Vanja.

Nat Immunol; 24(8): 1331-1344, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37443284

3.

Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium.

Kobayashi, Tetsuro; Voisin, Benjamin; Kim, Do Young; Kennedy, Elizabeth A; Jo, Jay-Hyun; Shih, Han-Yu; Truong, Amanda; Doebel, Thomas; Sakamoto, Keiko; Cui, Chang-Yi; Schlessinger, David; Moro, Kazuyo; Nakae, Susumu; Horiuchi, Keisuke; Zhu, Jinfang; Leonard, Warren J; Kong, Heidi H; Nagao, Keisuke.

Cell; 176(5): 982-997.e16, 2019 02 21.

Artículo en Inglés | MEDLINE | ID: mdl-30712873

4.

Thomas Alexander Waldmann (1930-2021).

Leonard, Warren J.

Nat Immunol; 22(12): 1467-1468, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34795446

5.

A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.

Xin, Annie; Masson, Frederick; Liao, Yang; Preston, Simon; Guan, Tianxia; Gloury, Renee; Olshansky, Moshe; Lin, Jian-Xin; Li, Peng; Speed, Terence P; Smyth, Gordon K; Ernst, Matthias; Leonard, Warren J; Pellegrini, Marc; Kaech, Susan M; Nutt, Stephen L; Shi, Wei; Belz, Gabrielle T; Kallies, Axel.

Nat Immunol; 17(4): 422-32, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26950239

6.

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers.

Roychoudhuri, Rahul; Clever, David; Li, Peng; Wakabayashi, Yoshiyuki; Quinn, Kylie M; Klebanoff, Christopher A; Ji, Yun; Sukumar, Madhusudhanan; Eil, Robert L; Yu, Zhiya; Spolski, Rosanne; Palmer, Douglas C; Pan, Jenny H; Patel, Shashank J; Macallan, Derek C; Fabozzi, Giulia; Shih, Han-Yu; Kanno, Yuka; Muto, Akihiko; Zhu, Jun; Gattinoni, Luca; O'Shea, John J; Okkenhaug, Klaus; Igarashi, Kazuhiko; Leonard, Warren J; Restifo, Nicholas P.

Nat Immunol; 17(7): 851-860, 2016 07.

Artículo en Inglés | MEDLINE | ID: mdl-27158840

7.

The Î³_c Family of Cytokines: Basic Biology to Therapeutic Ramifications.

Leonard, Warren J; Lin, Jian-Xin; O'Shea, John J.

Immunity; 50(4): 832-850, 2019 04 16.

Artículo en Inglés | MEDLINE | ID: mdl-30995502

8.

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1⁺ Stem-like CD8⁺ T Cells during Chronic Infection.

Hudson, William H; Gensheimer, Julia; Hashimoto, Masao; Wieland, Andreas; Valanparambil, Rajesh M; Li, Peng; Lin, Jian-Xin; Konieczny, Bogumila T; Im, Se Jin; Freeman, Gordon J; Leonard, Warren J; Kissick, Haydn T; Ahmed, Rafi.

Immunity; 51(6): 1043-1058.e4, 2019 12 17.

Artículo en Inglés | MEDLINE | ID: mdl-31810882

9.

Potentiating adoptive cell therapy using synthetic IL-9 receptors.

Kalbasi, Anusha; Siurala, Mikko; Su, Leon L; Tariveranmoshabad, Mito; Picton, Lora K; Ravikumar, Pranali; Li, Peng; Lin, Jian-Xin; Escuin-Ordinas, Helena; Da, Tong; Kremer, Sarah V; Sun, Amy L; Castelli, Sofia; Agarwal, Sangya; Scholler, John; Song, Decheng; Rommel, Philipp C; Radaelli, Enrico; Young, Regina M; Leonard, Warren J; Ribas, Antoni; June, Carl H; Garcia, K Christopher.

Nature; 607(7918): 360-365, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35676488

10.

PD-1 combination therapy with IL-2 modifies CD8⁺ T cell exhaustion program.

Hashimoto, Masao; Araki, Koichi; Cardenas, Maria A; Li, Peng; Jadhav, Rohit R; Kissick, Haydn T; Hudson, William H; McGuire, Donald J; Obeng, Rebecca C; Wieland, Andreas; Lee, Judong; McManus, Daniel T; Ross, James L; Im, Se Jin; Lee, Junghwa; Lin, Jian-Xin; Hu, Bin; West, Erin E; Scharer, Christopher D; Freeman, Gordon J; Sharpe, Arlene H; Ramalingam, Suresh S; Pellerin, Alex; Teichgräber, Volker; Greenleaf, William J; Klein, Christian; Goronzy, Jorg J; Umaña, Pablo; Leonard, Warren J; Smith, Kendall A; Ahmed, Rafi.

Nature; 610(7930): 173-181, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-36171288

11.

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

Vasanthakumar, Ajithkumar; Moro, Kazuyo; Xin, Annie; Liao, Yang; Gloury, Renee; Kawamoto, Shimpei; Fagarasan, Sidonia; Mielke, Lisa A; Afshar-Sterle, Shoukat; Masters, Seth L; Nakae, Susumu; Saito, Hirohisa; Wentworth, John M; Li, Peng; Liao, Wei; Leonard, Warren J; Smyth, Gordon K; Shi, Wei; Nutt, Stephen L; Koyasu, Shigeo; Kallies, Axel.

Nat Immunol; 16(3): 276-85, 2015 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-25599561

12.

An engineered IL-2 partial agonist promotes CD8⁺ T cell stemness.

Mo, Fei; Yu, Zhiya; Li, Peng; Oh, Jangsuk; Spolski, Rosanne; Zhao, Liang; Glassman, Caleb R; Yamamoto, Tori N; Chen, Yun; Golebiowski, Filip M; Hermans, Dalton; Majri-Morrison, Sonia; Picton, Lora K; Liao, Wei; Ren, Min; Zhuang, Xiaoxuan; Mitra, Suman; Lin, Jian-Xin; Gattinoni, Luca; Powell, Jonathan D; Restifo, Nicholas P; Garcia, K Christopher; Leonard, Warren J.

Nature; 597(7877): 544-548, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-34526724

13.

Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds.

Yang, Huilin; Ulge, Umut Y; Quijano-Rubio, Alfredo; Bernstein, Zachary J; Maestas, David R; Chun, Jung-Ho; Wang, Wentao; Lin, Jian-Xin; Jude, Kevin M; Singh, Srujan; Orcutt-Jahns, Brian T; Li, Peng; Mou, Jody; Chung, Liam; Kuo, Yun-Huai; Ali, Yasmin H; Meyer, Aaron S; Grayson, Warren L; Heller, Nicola M; Garcia, K Christopher; Leonard, Warren J; Silva, Daniel-Adriano; Elisseeff, Jennifer H; Baker, David; Spangler, Jamie B.

Nat Chem Biol; 19(9): 1127-1137, 2023 09.

Artículo en Inglés | MEDLINE | ID: mdl-37024727

14.

T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite.

Ballesteros-Tato, André; Randall, Troy D; Lund, Frances E; Spolski, Rosanne; Leonard, Warren J; León, Beatriz.

Immunity; 44(2): 259-73, 2016 Feb 16.

Artículo en Inglés | MEDLINE | ID: mdl-26825674

15.

Treatment of Relapsing HPV Diseases by Restored Function of Natural Killer Cells.

Lisco, Andrea; Hsu, Amy P; Dimitrova, Dimana; Proctor, Diana M; Mace, Emily M; Ye, Peiying; Anderson, Megan V; Hicks, Stephanie N; Grivas, Christopher; Hammoud, Dima A; Manion, Maura; Starrett, Gabriel J; Farrel, Alvin; Dobbs, Kerry; Brownell, Isaac; Buck, Christopher; Notarangelo, Luigi D; Orange, Jordan S; Leonard, Warren J; Orestes, Michael I; Peters, Anju T; Kanakry, Jennifer A; Segre, Julia A; Kong, Heidi H; Sereti, Irini.

N Engl J Med; 385(10): 921-929, 2021 09 02.

Artículo en Inglés | MEDLINE | ID: mdl-34469647

16.

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.

Ring, Aaron M; Lin, Jian-Xin; Feng, Dan; Mitra, Suman; Rickert, Mathias; Bowman, Gregory R; Pande, Vijay S; Li, Peng; Moraga, Ignacio; Spolski, Rosanne; Ozkan, Engin; Leonard, Warren J; Garcia, K Christopher.

Nat Immunol; 13(12): 1187-95, 2012 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-23104097

17.

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.

Mitra, Suman; Ring, Aaron M; Amarnath, Shoba; Spangler, Jamie B; Li, Peng; Ju, Wei; Fischer, Suzanne; Oh, Jangsuk; Spolski, Rosanne; Weiskopf, Kipp; Kohrt, Holbrook; Foley, Jason E; Rajagopalan, Sumati; Long, Eric O; Fowler, Daniel H; Waldmann, Thomas A; Garcia, K Christopher; Leonard, Warren J.

Immunity; 42(5): 826-38, 2015 May 19.

Artículo en Inglés | MEDLINE | ID: mdl-25992859

18.

Tetramerization of STAT5 promotes autoimmune-mediated neuroinflammation.

Monaghan, Kelly L; Aesoph, Drake; Ammer, Amanda G; Zheng, Wen; Rahimpour, Shokofeh; Farris, Breanne Y; Spinner, Camille A; Li, Peng; Lin, Jian-Xin; Yu, Zu-Xi; Lazarevic, Vanja; Hu, Gangqing; Leonard, Warren J; Wan, Edwin C K.

Proc Natl Acad Sci U S A; 118(52)2021 12 28.

Artículo en Inglés | MEDLINE | ID: mdl-34934004

19.

ROGUE: an R Shiny app for RNA sequencing analysis and biomarker discovery.

Farrel, Alvin; Li, Peng; Veenbergen, Sharon; Patel, Khushbu; Maris, John M; Leonard, Warren J.

BMC Bioinformatics; 24(1): 303, 2023 Jul 29.

Artículo en Inglés | MEDLINE | ID: mdl-37516886

20.

Co-localization of clusters of TCR-regulated genes with TAD rearrangements.

Gao, Galen F; Li, Peng; Leonard, Warren J.

BMC Genomics; 24(1): 650, 2023 Oct 28.

Artículo en Inglés | MEDLINE | ID: mdl-37898735

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