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1.

Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells.

Levite, Mia; Zelig, Daniel; Friedman, Alon; Ilouz, Nili; Eilam, Raya; Bromberg, Zohar; Ramadhan Lasu, Ally Ahmed; Arbel-Alon, Sagit; Edvardson, Shimon; Tarshish, Mark; Riek, Lul P; Lako, Richard Lino; Reubinoff, Benjamin; Lebendiker, Mario; Yaish, Dayana; Stavsky, Alexandra; Galun, Eithan.

J Autoimmun; 112: 102462, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32561150

2.

Instantaneous depolarization of T cells via dopamine receptors, and inhibition of activated T cells of Psoriasis patients and inflamed human skin, by D1-like receptor agonist: Fenoldopam.

Keren, Aviad; Gilhar, Amos; Ullmann, Yehuda; Zlotkin-Frusic, Marina; Soroka, Yoram; Domb, Abraham J; Levite, Mia.

Immunology; 158(3): 171-193, 2019 11.

Artículo en Inglés | MEDLINE | ID: mdl-31424569

3.

Glutamate, T cells and multiple sclerosis.

Levite, Mia.

J Neural Transm (Vienna); 124(7): 775-798, 2017 07.

Artículo en Inglés | MEDLINE | ID: mdl-28236206

4.

Dopamine, T cells and multiple sclerosis (MS).

Levite, Mia; Marino, Franca; Cosentino, Marco.

J Neural Transm (Vienna); 124(5): 525-542, 2017 05.

Artículo en Inglés | MEDLINE | ID: mdl-28283756

5.

Normal human CD4(+) helper T cells express Kv1.1 voltage-gated K(+) channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway.

Fellerhoff-Losch, Barbara; Korol, Sergiy V; Ganor, Yonatan; Gu, Songhai; Cooper, Itzik; Eilam, Raya; Besser, Michal; Goldfinger, Meidan; Chowers, Yehuda; Wank, Rudolf; Birnir, Bryndis; Levite, Mia.

J Neural Transm (Vienna); 123(3): 137-57, 2016 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-26611796

6.

Glutamate receptor antibodies in neurological diseases: anti-AMPA-GluR3 antibodies, anti-NMDA-NR1 antibodies, anti-NMDA-NR2A/B antibodies, anti-mGluR1 antibodies or anti-mGluR5 antibodies are present in subpopulations of patients with either: epilepsy, encephalitis, cerebellar ataxia, systemic lupus erythematosus (SLE) and neuropsychiatric SLE, Sjogren's syndrome, schizophrenia, mania or stroke. These autoimmune anti-glutamate receptor antibodies can bind neurons in few brain regions, activate glutamate receptors, decrease glutamate receptor's expression, impair glutamate-induced signaling and function, activate blood brain barrier endothelial cells, kill neurons, damage the brain, induce behavioral/psychiatric/cognitive abnormalities and ataxia in animal models, and can be removed or silenced in some patients by immunotherapy.

Levite, Mia.

J Neural Transm (Vienna); 121(8): 1029-75, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-25081016

7.

The neurotransmitter glutamate and human T cells: glutamate receptors and glutamate-induced direct and potent effects on normal human T cells, cancerous human leukemia and lymphoma T cells, and autoimmune human T cells.

Ganor, Yonatan; Levite, Mia.

J Neural Transm (Vienna); 121(8): 983-1006, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24584970

8.

Towards neuroimmunotherapy for cancer: the neurotransmitters glutamate, dopamine and GnRH-II augment substantially the ability of T cells of few head and neck cancer patients to perform spontaneous migration, chemotactic migration and migration towards the autologous tumor, and also elevate markedly the expression of CD3zeta and CD3epsilon TCR-associated chains.

Saussez, Sven; Laumbacher, Barbara; Chantrain, Gilbert; Rodriguez, Alexandra; Gu, Songhai; Wank, Rudolf; Levite, Mia.

J Neural Transm (Vienna); 121(8): 1007-27, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-25030361

9.

Neuro faces of beneficial T cells: essential in brain, impaired in aging and neurological diseases, and activated functionally by neurotransmitters and neuropeptides.

Levite, Mia.

Neural Regen Res; 18(6): 1165-1178, 2023 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-36453390

10.

The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs.

Chen, Alon; Ganor, Yonatan; Rahimipour, Shai; Ben-Aroya, Nurit; Koch, Yitzhak; Levite, Mia.

Nat Med; 8(12): 1421-6, 2002 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-12447356

11.

T Cells Plead for Rejuvenation and Amplification; With the Brain's Neurotransmitters and Neuropeptides We Can Make It Happen.

Levite, Mia.

Front Immunol; 12: 617658, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-33868232

12.

Autoimmune Epilepsy - Novel Multidisciplinary Analysis, Discoveries and Insights.

Levite, Mia; Goldberg, Hadassa.

Front Immunol; 12: 762743, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-35095841

13.

Neurotransmitters and Neuropeptides decrease PD-1 in T cells of healthy subjects and patients with hepatocellular carcinoma (HCC), and increase their proliferation and eradication of HCC cells.

Levite, Mia; Safadi, Rifaat; Milgrom, Yael; Massarwa, Muhammad; Galun, Eithan.

Neuropeptides; 89: 102159, 2021 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-34293596

14.

Macrophage migration inhibitory factor in Nodding syndrome.

Benedek, Gil; Abed El Latif, Mahmoud; Miller, Keren; Rivkin, Mila; Ahmed Ramadhan Lasu, Ally; P Riek, Lul; Lako, Richard; Edvardson, Shimon; Arbel-Alon, Sagit; Galun, Eithan; Levite, Mia.

PLoS Negl Trop Dis; 15(10): e0009821, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34662363

15.

Protection or susceptibility to devastating childhood epilepsy: Nodding Syndrome associates with immunogenetic fingerprints in the HLA binding groove.

Benedek, Gil; Abed El Latif, Mahmoud; Miller, Keren; Rivkin, Mila; Ramadhan Lasu, Ally Ahmed; Riek, Lul P; Lako, Richard; Edvardson, Shimon; Alon, Sagit-Arbel; Galun, Eithan; Levite, Mia.

PLoS Negl Trop Dis; 14(7): e0008436, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32639997

16.

Neurotransmitters activate T-cells and elicit crucial functions via neurotransmitter receptors.

Levite, Mia.

Curr Opin Pharmacol; 8(4): 460-71, 2008 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-18579442

17.

Identification of the novel HLA-B allele, HLA-B*15:539, in a South-Sudanese individual.

Benedek, Gil; Abed El-Latif, Mahmoud; Miller, Keren; Galun, Eithan; Levite, Mia.

HLA; 94(4): 380-381, 2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-31271260

18.

Functional voltage-gated sodium channels are expressed in human intestinal epithelial cells.

Barshack, Iris; Levite, Mia; Lang, Alon; Fudim, Ella; Picard, Orit; Ben Horin, Shomron; Chowers, Yehuda.

Digestion; 77(2): 108-17, 2008.

Artículo en Inglés | MEDLINE | ID: mdl-18391489

19.

Acute intermittent porphyria, Rasmussen encephalitis, or both?

Tziperman, Barak; Garty, Ben-Zion; Schoenfeld, Nili; Hoffer, Vered; Watemberg, Nathan; Lev, Dorit; Ganor, Yonathan; Levite, Mia; Lerman-Sagie, Tally.

J Child Neurol; 22(1): 99-105, 2007 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-17608316

20.

Dopamine by itself activates either D2, D3 or D1/D5 dopaminergic receptors in normal human T-cells and triggers the selective secretion of either IL-10, TNFalpha or both.

Besser, Michal J; Ganor, Yonatan; Levite, Mia.

J Neuroimmunol; 169(1-2): 161-71, 2005 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-16150496

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Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells.

Instantaneous depolarization of T cells via dopamine receptors, and inhibition of activated T cells of Psoriasis patients and inflamed human skin, by D1-like receptor agonist: Fenoldopam.

Glutamate, T cells and multiple sclerosis.

Dopamine, T cells and multiple sclerosis (MS).

Normal human CD4(+) helper T cells express Kv1.1 voltage-gated K(+) channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway.

The neurotransmitter glutamate and human T cells: glutamate receptors and glutamate-induced direct and potent effects on normal human T cells, cancerous human leukemia and lymphoma T cells, and autoimmune human T cells.

Neuro faces of beneficial T cells: essential in brain, impaired in aging and neurological diseases, and activated functionally by neurotransmitters and neuropeptides.

The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs.

T Cells Plead for Rejuvenation and Amplification; With the Brain's Neurotransmitters and Neuropeptides We Can Make It Happen.

Autoimmune Epilepsy - Novel Multidisciplinary Analysis, Discoveries and Insights.

Neurotransmitters and Neuropeptides decrease PD-1 in T cells of healthy subjects and patients with hepatocellular carcinoma (HCC), and increase their proliferation and eradication of HCC cells.

Macrophage migration inhibitory factor in Nodding syndrome.

Protection or susceptibility to devastating childhood epilepsy: Nodding Syndrome associates with immunogenetic fingerprints in the HLA binding groove.

Neurotransmitters activate T-cells and elicit crucial functions via neurotransmitter receptors.

Identification of the novel HLA-B allele, HLA-B*15:539, in a South-Sudanese individual.

Functional voltage-gated sodium channels are expressed in human intestinal epithelial cells.

Acute intermittent porphyria, Rasmussen encephalitis, or both?

Dopamine by itself activates either D2, D3 or D1/D5 dopaminergic receptors in normal human T-cells and triggers the selective secretion of either IL-10, TNFalpha or both.