Detalles de la búsqueda
1.
Structure-activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors.
Bioorg Med Chem Lett;
81: 129143, 2023 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36669575
2.
Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1.
Bioorg Med Chem Lett;
88: 129280, 2023 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37054759
3.
Scaffold modifications to the 4-(4,4-dimethylpiperidinyl) 2,6-dimethylpyridinyl class of HIV-1 allosteric integrase inhibitors.
Bioorg Med Chem;
67: 116833, 2022 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35605346
4.
Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form.
Proc Natl Acad Sci U S A;
115(13): 3249-3254, 2018 03 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29531094
5.
Neutrophil-predominant bullous pemphigoid induced by checkpoint inhibitors: A case series.
J Cutan Pathol;
47(8): 742-746, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32196722
6.
Pemphigus foliaceus in a patient with gastrointestinal stromal tumor treated with adjuvant imatinib mesylate.
Dermatol Online J;
26(6)2020 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32815695
7.
Initial Clinical Guidelines for Co-Occurring Autism Spectrum Disorder and Gender Dysphoria or Incongruence in Adolescents.
J Clin Child Adolesc Psychol;
47(1): 105-115, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-27775428
8.
Dermatology ECHO - an innovative solution to address limited access to dermatology expertise.
Rural Remote Health;
18(1): 4415, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29409325
9.
Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop.
J Biol Chem;
291(4): 1854-1865, 2016 Jan 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-26627831
10.
Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core.
Bioorg Med Chem Lett;
25(9): 1856-63, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25845281
11.
Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.
Proc Natl Acad Sci U S A;
108(37): 15366-71, 2011 Sep 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-21896751
12.
Evidence-based approach of treatment options for postoperative knee pain.
Phys Sportsmed;
42(2): 58-70, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24875973
13.
Design, Structure-Activity Relationships, and In Vivo Evaluation of Potent and Brain-Penetrant Imidazo[1,2-b]pyridazines as Glycogen Synthase Kinase-3ß (GSK-3ß) Inhibitors.
J Med Chem;
66(6): 4231-4252, 2023 03 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-36950863
14.
Discovery of 2-(Anilino)pyrimidine-4-carboxamides as Highly Potent, Selective, and Orally Active Glycogen Synthase Kinase-3 (GSK-3) Inhibitors.
J Med Chem;
66(11): 7534-7552, 2023 06 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37235865
15.
Design, Synthesis, and Preclinical Profiling of GSK3739936 (BMS-986180), an Allosteric Inhibitor of HIV-1 Integrase with Broad-Spectrum Activity toward 124/125 Polymorphs.
J Med Chem;
65(6): 4949-4971, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35235334
16.
Discovery and Preclinical Profiling of GSK3839919, a Potent HIV-1 Allosteric Integrase Inhibitor.
ACS Med Chem Lett;
13(6): 972-980, 2022 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35707159
17.
SGX393 inhibits the CML mutant Bcr-AblT315I and preempts in vitro resistance when combined with nilotinib or dasatinib.
Proc Natl Acad Sci U S A;
105(14): 5507-12, 2008 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-18367669
18.
Discovery and Optimization of Novel Pyrazolopyrimidines as Potent and Orally Bioavailable Allosteric HIV-1 Integrase Inhibitors.
J Med Chem;
63(5): 2620-2637, 2020 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32081010
19.
BrainSTARS: pilot data on a team-based intervention program for students who have acquired brain injury.
J Head Trauma Rehabil;
24(3): 166-77, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19461364
20.
5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors.
J Med Chem;
62(3): 1348-1361, 2019 02 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30609350