Detalles de la búsqueda
1.
Impact of Integrase Sequences from HIV-1 Subtypes A6/A1 on the In Vitro Potency of Cabotegravir or Rilpivirine.
Antimicrob Agents Chemother;
66(3): e0170221, 2022 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34978890
2.
GSK3732394: a Multi-specific Inhibitor of HIV Entry.
J Virol;
93(20)2019 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31375580
3.
A Novel gp41-Binding Adnectin with Potent Anti-HIV Activity Is Highly Synergistic when Linked to a CD4-Binding Adnectin.
J Virol;
92(14)2018 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29743355
4.
The design, synthesis and structure-activity relationships associated with C28 amine-based betulinic acid derivatives as inhibitors of HIV-1 maturation.
Bioorg Med Chem Lett;
28(9): 1550-1557, 2018 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29631960
5.
Discovery and Characterization of a Novel CD4-Binding Adnectin with Potent Anti-HIV Activity.
Antimicrob Agents Chemother;
61(8)2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28584151
6.
Identification and Characterization of BMS-955176, a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Antiviral Spectrum, and Gag Polymorphic Coverage.
Antimicrob Agents Chemother;
60(7): 3956-69, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27090171
7.
C-3 benzoic acid derivatives of C-3 deoxybetulinic acid and deoxybetulin as HIV-1 maturation inhibitors.
Bioorg Med Chem;
24(8): 1757-70, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26968652
8.
Activity of the HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068, against CD4-independent viruses and HIV-1 envelopes resistant to other entry inhibitors.
Antimicrob Agents Chemother;
57(9): 4172-80, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23774428
9.
In vitro cross-resistance profile of nucleoside reverse transcriptase inhibitor (NRTI) BMS-986001 against known NRTI resistance mutations.
Antimicrob Agents Chemother;
57(11): 5500-8, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23979732
10.
Evaluation of HIV-1 inhibition by stereoisomers and analogues of the sesquiterpenoid hydroquinone peyssonol A.
Bioorg Med Chem Lett;
23(7): 2192-6, 2013 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23434230
11.
Clinical evidence for a lack of cross-resistance between temsavir and ibalizumab or maraviroc.
AIDS;
36(1): 11-18, 2022 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34628442
12.
Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel C-17 Amine Derivatives Based on GSK3640254 as HIV-1 Maturation Inhibitors with Broad Spectrum Activity.
J Med Chem;
65(23): 15935-15966, 2022 12 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36441509
13.
The Discovery of GSK3640254, a Next-Generation Inhibitor of HIV-1 Maturation.
J Med Chem;
65(18): 11927-11948, 2022 09 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36044257
14.
Design, Synthesis, and SAR of C-3 Benzoic Acid, C-17 Triterpenoid Derivatives. Identification of the HIV-1 Maturation Inhibitor 4-((1 R,3a S,5a R,5b R,7a R,11a S,11b R,13a R,13b R)-3a-((2-(1,1-Dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1 H-cyclopenta[ a]chrysen-9-yl)benzoic Acid (GSK3532795, BMS-955176).
J Med Chem;
61(16): 7289-7313, 2018 08 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-30067361
15.
Discovery of BMS-955176, a Second Generation HIV-1 Maturation Inhibitor with Broad Spectrum Antiviral Activity.
ACS Med Chem Lett;
7(6): 568-72, 2016 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27326328
16.
Pyrazolo-Piperidines Exhibit Dual Inhibition of CCR5/CXCR4 HIV Entry and Reverse Transcriptase.
ACS Med Chem Lett;
6(7): 753-7, 2015 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-26191361
17.
Biochemical analysis of HIV-1 integrase variants resistant to strand transfer inhibitors.
J Biol Chem;
283(35): 23599-609, 2008 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-18577511
18.
Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.
J Biol Chem;
282(43): 31186-96, 2007 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-17715137
19.
Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity.
Bioorg Med Chem Lett;
17(16): 4592-8, 2007 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17576060
20.
Respiratory syncytial virus fusion inhibitors. Part 4: optimization for oral bioavailability.
Bioorg Med Chem Lett;
17(4): 895-901, 2007 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17169560