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1.
Ann Vasc Surg ; 69: 449.e11-449.e16, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32502671

RESUMEN

BACKGROUND: Structural heart defects, secondary to congenital malformations, have been commonly repaired by open cardiac surgery. Endovascular technology enables these repairs to be performed with fewer complications and better recovery. However, endovascular therapy can be associated with major complications as device dislocation or embolization. We present the case of migration of an Amplatzer occluder device into the abdominal aorta and its surgical retrieval. CLINICAL CASE: A 10-year-old child with ostium secundum-type interatrial communication underwent endovascular repair in our center. Cardiologists sorted out the atrial communication by endovascular deployment of an Amplatzer device. The 24-h ultrasound control study showed the loss of the occluder. An angio-CT scan showed the migration of the Amplatzer into the juxtarenal abdominal aorta. Initially, an endovascular rescue was attempted but was not effective. Our vascular team performed a median laparotomy, control of the abdominal aorta proximal to the renal arteries, and control of the renal arteries and the infrarenal aorta. We performed a transverse arteriotomy, and the material was removed. Subsequently, the arteriotomy was closed directly without any patch. Postoperative evolution was uneventful. COMMENTS: Most of the migrations and embolizations of the devices to close interatrial communications remain intracardiac. Although embolization of the abdominal aorta is only reported sporadically, it could cause a major vascular complication. Percutaneous retrieval of the device is currently recommended, with conventional surgery being the efficient treatment in case of endovascular failure or severe damage to the aorta.


Asunto(s)
Aorta Abdominal/cirugía , Cateterismo Cardíaco/instrumentación , Remoción de Dispositivos , Migración de Cuerpo Extraño/cirugía , Defectos del Tabique Interatrial/terapia , Dispositivo Oclusor Septal , Aorta Abdominal/diagnóstico por imagen , Cateterismo Cardíaco/efectos adversos , Niño , Migración de Cuerpo Extraño/diagnóstico por imagen , Migración de Cuerpo Extraño/etiología , Defectos del Tabique Interatrial/diagnóstico por imagen , Humanos , Resultado del Tratamiento
2.
Ann Vasc Surg ; 67: 306-315, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32173472

RESUMEN

BACKGROUND: Endovascular techniques have become an essential tool for treatment of thoracic aortic pathology. The objective of this study was to analyze indications and results of thoracic endovascular aortic repair (TEVAR) in vascular surgery units, through a retrospective and multicentric national registry called Regis-TEVAR. METHODS: From 2012 to 2016, a total of 287 patients from 11 vascular surgery units, treated urgently and electively, were recruited consecutively. The primary variables analyzed are mortality, survival, and reintervention rate. The following indications for TEVAR were also analyzed: aortic dissections, thoracic aneurysms, traumatisms, and intramural hematomas or penetrating ulcers, as well as results and postoperative complications in accordance with each indication. RESULTS: Of the 287 TEVAR performed (239 men, mean age 64.1 ± 14.1 years), 155 were because of aortic aneurysm (54%), 90 because of type B aortic dissection (31.4%), 36 because of traumatic aortic rupture (12.5%), and 6 because of penetrating ulcers or intramural hematomas (2.1%). Overall mortality at 30 days was 11.5% (18.5% in urgent and 5.3% in elective), being higher in dissections (13.3%). The median actuarial survival was 73% at 4 years. The stroke rate was 3.1%, and the rate of spinal cord ischemia was 4.9%. Aortic reoperations were necessary in 23 patients (8.1%). CONCLUSIONS: This registry provides complete and reliable information on real clinical practice of TEVAR in Spain, with results similar to international series of open surgery. In accordance with these data, TEVAR can be performed with acceptable morbidity and mortality and with low rates of postoperative complications.


Asunto(s)
Aorta Torácica/cirugía , Enfermedades de la Aorta/cirugía , Implantación de Prótesis Vascular , Procedimientos Endovasculares , Anciano , Aorta Torácica/diagnóstico por imagen , Enfermedades de la Aorta/diagnóstico por imagen , Enfermedades de la Aorta/mortalidad , Implantación de Prótesis Vascular/efectos adversos , Implantación de Prótesis Vascular/instrumentación , Implantación de Prótesis Vascular/mortalidad , Procedimientos Endovasculares/efectos adversos , Procedimientos Endovasculares/instrumentación , Procedimientos Endovasculares/mortalidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/mortalidad , Complicaciones Posoperatorias/cirugía , Sistema de Registros , Reoperación , Estudios Retrospectivos , Factores de Riesgo , España , Factores de Tiempo , Resultado del Tratamiento
3.
Foot Ankle Surg ; 24(1): 60-64, 2018 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29413776

RESUMEN

BACKGROUND: The aim of this cohort study was to assess the inter-observer agreement of three diabetic foot classification systems: the Wagner, the University of Texas and the PEDIS. METHODS: We included 250 consecutive patients diagnosed of diabetic foot syndrome in 2009-2013. Wound scores were recorded at admission and a reevaluation was performed simultaneously or 24h later by a different evaluator. Demographical, laboratory data and associated risk factors were obtained from the patients' medical records. RESULTS: The Kappa coefficient showed a moderate inter-observer agreement between the first evaluation and the reevaluation for Wagner scale (Kappa=0.55; 95% CI: 0.507-0.593), University of Texas scale (Kappa=0.513; 95% CI: 0.463-0.563) and for PEDIS scale (Kappa=0.574; 95% CI: 0.522-0.626). CONCLUSIONS: This moderate agreement shows that these scales should not be used alone for management decisions regarding diabetic foot syndrome and should, therefore, be integrated with other clinical data to ensure an adequate handover.


Asunto(s)
Pie Diabético/clasificación , Índice de Severidad de la Enfermedad , Anciano , Amputación Quirúrgica , Diabetes Mellitus Tipo 1/complicaciones , Diabetes Mellitus Tipo 2/complicaciones , Pie Diabético/diagnóstico , Pie Diabético/etiología , Pie Diabético/cirugía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Variaciones Dependientes del Observador , Estudios Prospectivos , Heridas y Lesiones/clasificación
4.
Enferm Infecc Microbiol Clin ; 34(8): 477-83, 2016 Oct.
Artículo en Español | MEDLINE | ID: mdl-26656792

RESUMEN

INTRODUCTION: The aim of the study was to assess whether the penetration of antibiotics is affected by decreased tissue perfusion in patients with limb ischaemia, thus reducing its concentration in tissues below the minimum inhibitory concentration (MIC) breakpoints of antibiotics for different microorganisms. METHODS: Prospective study. Candidates for major amputation with critical lower limb ischaemia and an infection on antibiotic treatment, were included. Three levels of perfusion in the lower limb were determined by measuring the transcutaneous oxygen pressure (TcPO2). A central line blood specimen, as well as biopsies of the skin, muscle, and bone, were taken at each perfusion level. The antibiotic concentration was determined using HPLC. RESULTS: The total number of cases was 61 (46 patients): 6 clindamycin, 9 vancomycin, 8 linezolid, 18 levofloxacin, 9 ceftazidime, and 11 meropenem. Statistically significant differences were found in TcPO2 at all levels (ANOVA, P=.000). The vancomycin, levofloxacin and ceftazidime skin concentration depends on perfusion. Vancomycin and levofloxacin diffusion in bone is worse than in other tissues. Ceftazidime concentration does not exceed the MIC breakpoint of Pseudomonas aeruginosa in ischaemic tissues. CONCLUSIONS: Meropenem and linezolid diffuse in all tissues, regardless of perfusion, reaching concentrations above the MIC of the target microorganisms, ensuring its effectiveness in ischaemic tissues.


Asunto(s)
Antibacterianos/farmacocinética , Isquemia/metabolismo , Extremidad Inferior/irrigación sanguínea , Anciano , Ceftazidima , Cromatografía Líquida de Alta Presión , Clindamicina/farmacocinética , Femenino , Humanos , Levofloxacino/farmacocinética , Linezolid/farmacocinética , Masculino , Meropenem , Pruebas de Sensibilidad Microbiana , Estudios Prospectivos , Piel/metabolismo , Tienamicinas/farmacocinética , Vancomicina/farmacocinética
5.
Cir Esp ; 94(3): 144-50, 2016 Mar.
Artículo en Inglés, Español | MEDLINE | ID: mdl-26791174

RESUMEN

INTRODUCTION: Traditionally, anterior accessory great saphenous vein insufficiency was managed by crossectomy and resection of varicose veins. The aim of this paper is to show the safety and efficacy of a new therapeutic strategy for anterior accessory great saphenous varicose veins. METHODS: This non-randomised prospective study included 65 patients with varicose veins from the anterior accessory great saphenous vein. The novelty of the technique is to avoid the great saphenous vein crossectomy and perform just flebectomy of the visible veins. Venous duplex studies were performed preoperatively, a month and a year postoperatively. The clinical assessment was done by the Fligelstone scale. RESULTS: The baseline CEAP clinical classification was: 58% C2, 26% C3 and 15% C4-6. The new strategy was applied to all cases. COMPLICATIONS: 3 haematomas, 7 cases of asymptomatic partial anterior saphenous thrombosis. Reduction of the initial average diameter was from 6.4 mm anterior saphenous to 3.4 mm by one year (p <0.001). At twelve months a forward flow is maintained in 82% of cases. Recurrence of varicose veins was 8%. All patients improved their clinical status based on the Fligelstone scale. Cases with saphenous diameter bigger than 7.5 mm and obesity were identified as predictors of worse clinical and hemodynamic outcome. CONCLUSIONS: This modified surgical strategy for anterior saphenous varicose veins results in better clinical outcomes at one year postoperatively.


Asunto(s)
Vena Safena/cirugía , Várices/cirugía , Hemodinámica , Humanos , Estudios Prospectivos , Recurrencia
6.
Ann Vasc Surg ; 27(8): 1162-8, 2013 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-23953665

RESUMEN

BACKGROUND: The therapeutic and diagnostic approach in deep vein thrombosis (DVT) has changed enormously in the last two decades with the introduction of ultrasound, low-molecular-weight heparin (LMWH), and premature motion. The aim of this study is to evaluate these changes and analyze their clinical and economic aspects. METHODS: We registered all inpatients with a diagnosis of DVT during 1994 (n=110) and 2009 (n=75) and their sociodemographic and clinical features in a descriptive observational design. We performed a comparison of diagnostic techniques, length of stay, inpatient complications, and costs thus derived for both series, based on 2009 prices, so that we could get comparable results. RESULTS: Ninety-one percent of inpatients in 1994 were diagnosed by venography, whereas, in 2009, the diagnosis was based on clinical features, D-dimer, and ultrasound in 100% of patients. Inpatient treatment went from 7% LMWH in 1994 to 96% in 2009, and as outpatient from 82% acenocumarol to 90.6% LMWH. Complications decreased by 13.3%. Length of stay was 2.7 higher in 1994. Globally, the cost per patient decreased by 63.39%, based primarily on reduced length of stay. CONCLUSIONS: The current diagnostic and therapeutic approach in DVT allows for effective treatment, fewer complications, and a drastic reduction in inpatient costs.


Asunto(s)
Anticoagulantes , Heparina de Bajo-Peso-Molecular , Costos de Hospital , Pacientes Internos , Tromboembolia Venosa , Adulto , Anciano , Anticoagulantes/economía , Anticoagulantes/uso terapéutico , Biomarcadores/sangre , Ahorro de Costo , Análisis Costo-Beneficio , Costos de los Medicamentos , Femenino , Productos de Degradación de Fibrina-Fibrinógeno/análisis , Heparina de Bajo-Peso-Molecular/economía , Heparina de Bajo-Peso-Molecular/uso terapéutico , Humanos , Tiempo de Internación/economía , Masculino , Persona de Mediana Edad , Modelos Económicos , Flebografía/economía , Valor Predictivo de las Pruebas , Sistema de Registros , Factores de Tiempo , Resultado del Tratamiento , Tromboembolia Venosa/sangre , Tromboembolia Venosa/diagnóstico , Tromboembolia Venosa/economía , Tromboembolia Venosa/terapia
7.
J Diabetes Complications ; 30(2): 329-34, 2016 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-26644145

RESUMEN

AIMS: To establish if the microbiology and the TEXAS, PEDIS and Wagner wound classifications of the diabetic foot syndrome (DFS) predict amputation. METHODS: Prospective cohort study of 250 patients with DFS from 2009 to 2013. Tissue samples for culture were obtained and wound classification scores were recorded at admission. RESULTS: Infection was monomicrobial in 131 patients (52%). Staphylococcus aureus was the most frequent pathogen (76 patients, 30%); being methicillin-resistant S. aureus in 26% (20/76) Escherichia coli and Enterobacter faecalis were 2nd and 3rd most frequent pathogens. Two hundred nine patients (85%) needed amputation being major in 25 patients (10%). The three wound scales associated minor amputation but did not predict this outcome. Predictors of minor amputation in the multivariate analysis were the presence of osteomyelitis, the location of the wound in the forefoot and of major amputation elevated C reactive proteine (CRP) levels. A low ankle-brachial index (ABI) predicted major amputation in the follow-up. Overall, 74% of gram-positives were sensitive to quinolones and 98% to vancomycin and 90% of gram-negatives to cefotaxime and 95% to carbapenems. CONCLUSIONS: The presence of osteomyelitis and the location of the wound in the forefoot predict minor amputation and elevated CRP levels predict major amputation. In the follow-up a low ABI predicts major amputation.


Asunto(s)
Pie Diabético/diagnóstico , Pie Diabético/microbiología , Pie/microbiología , Pie/patología , Anciano , Amputación Quirúrgica/estadística & datos numéricos , Índice Tobillo Braquial , Estudios de Cohortes , Pie Diabético/patología , Pie Diabético/cirugía , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Pronóstico , Proyectos de Investigación , Factores de Riesgo , Infecciones Estafilocócicas/complicaciones , Infecciones Estafilocócicas/diagnóstico , Infecciones Estafilocócicas/patología , Staphylococcus aureus/aislamiento & purificación
8.
Enferm. infecc. microbiol. clín. (Ed. impr.) ; 34(8): 477-483, oct. 2016. ilus, tab, graf
Artículo en Español | IBECS (España) | ID: ibc-156250

RESUMEN

INTRODUCCIÓN: El objetivo principal del estudio ha sido valorar si la penetración de antibióticos se ve influenciada por la perfusión tisular disminuida en pacientes con isquemia de miembros, reduciendo la concentración alcanzada en tejidos por debajo de los puntos de corte (breakpoints) de la concentración mínima inhibitoria (CMI) de los antimicrobianos utilizados para diferentes patógenos. MÉTODOS: Estudio prospectivo. Se incluyeron candidatos a amputación mayor con isquemia crítica de miembro inferior e infección en tratamiento antibiótico. Se determinaron 3 niveles de perfusión en el miembro inferior, midiendo la presión transcutánea de oxígeno (TcPO2). Se extrajo una muestra de sangre de vía central así como biopsias de piel, músculo y hueso de cada uno de los niveles de perfusión. Se determinó la concentración del antibiótico mediante HPLC. RESULTADOS: El número total de casos es de 61 (46 pacientes): 6 clindamicina, 9 vancomicina, 8 linezolid, 18 levofloxacino, 9 ceftazidima y 11 meropenem. Se encuentran diferencias estadísticamente significativas entre todos los niveles de TcPO2 (ANOVA, p = 0,000). La concentración en piel de vancomicina, levofloxacino y ceftazidima depende del nivel de perfusión. Vancomicina y levofloxacino difunden peor en hueso que en el resto de tejidos. La concentración de ceftazidima no supera el punto de corte de Pseudomonas aeruginosa en tejidos isquémicos. CONCLUSIONES: Linezolid y meropenem difunden en todos los tejidos independientemente de la perfusión, alcanzando concentraciones superiores a la CMI de los microrganismos diana, asegurando su efectividad en tejidos isquémicos


INTRODUCTION: The aim of the study was to assess whether the penetration of antibiotics is affected by decreased tissue perfusion in patients with limb ischaemia, thus reducing its concentration in tissues below the minimum inhibitory concentration (MIC) breakpoints of antibiotics for different microorganisms. METHODS: rospective study. Candidates for major amputation with critical lower limb ischaemia and an infection on antibiotic treatment, were included. Three levels of perfusion in the lower limb were determined by measuring the transcutaneous oxygen pressure (TcPO2). A central line blood specimen, as well as biopsies of the skin, muscle, and bone, were taken at each perfusion level. The antibiotic concentration was determined using HPLC. RESULTS: The total number of cases was 61 (46 patients): 6 clindamycin, 9 vancomycin, 8 linezolid, 18 levofloxacin, 9 ceftazidime, and 11 meropenem. Statistically significant differences were found in TcPO2 at all levels (ANOVA, P=.000). The vancomycin, levofloxacin and ceftazidime skin concentration depends on perfusion. Vancomycin and levofloxacin diffusion in bone is worse than in other tissues. Ceftazidime concentration does not exceed the MIC breakpoint of Pseudomonas aeruginosa in ischaemic tissues. CONCLUSIONS: Meropenem and linezolid diffuse in all tissues, regardless of perfusion, reaching concentrations above the MIC of the target microorganisms, ensuring its effectiveness in ischaemic tissues


Asunto(s)
Humanos , Isquemia/tratamiento farmacológico , Enfermedades Vasculares Periféricas/tratamiento farmacológico , Antibacterianos/farmacocinética , Estudios Prospectivos , Pruebas de Sensibilidad Microbiana/métodos
9.
Cir. Esp. (Ed. impr.) ; 94(3): 144-150, mar. 2016. tab, ilus
Artículo en Español | IBECS (España) | ID: ibc-150084

RESUMEN

INTRODUCCIÓN: Tradicionalmente la insuficiencia de safena anterior se trataba mediante crosectomía y resección de los paquetes varicosos. El objetivo del trabajo es mostrar la seguridad y eficacia de una nueva estrategia terapéutica en las varices dependientes de la vena safena magna accesoria anterior. MÉTODOS: Estudio prospectivo no ramdomizado que incluyó 65 pacientes con varices dependientes de la safena anterior con safena interna anterógrada. La modificación en la técnica consiste en hacer solamente flebectomía de los paquetes varicosos, sin ligar el cayado de la safena. Se realizó un estudio hemodinámico venoso preoperatorio, al mes y al año, y para la valoración clínica se utilizó la escala de Fligelstone. RESULTADOS: Clasificación clínica basal CEAP: C2 58%, C3 26% y C4-6 15%. Complicaciones: 3 hematomas, 7 casos de trombosis parciales asintomáticas de safena anterior. Se observó una reducción del diámetro medio inicial de safena anterior de 6,4 mm a 3,4 mm al año (p < 0,001). A los doce meses mantenían un flujo anterógrado el 82% de los casos. Hubo una recidiva de varices visibles en el 8% de los casos. Todos los pacientes han reflejado una mejoría clínica en la escala de Fligelstone. El diámetro de safena anterior mayor de 7,5 mm y la obesidad se identifican como predictores de un peor resultado clínico y hemodinámico. CONCLUSIONES: La modificación de la estrategia quirúrgica sobre las varices dependientes de la safena anterior presenta un resultado clínico favorable al año de la intervención


INTRODUCTION: Traditionally, anterior accessory great saphenous vein insufficiency was managed by crossectomy and resection of varicose veins. The aim of this paper is to show the safety and efficacy of a new therapeutic strategy for anterior accessory great saphenous varicose veins. METHODS: This non-randomised prospective study included 65 patients with varicose veins from the anterior accessory great saphenous vein. The novelty of the technique is to avoid the great saphenous vein crossectomy and perform just flebectomy of the visible veins. Venous duplex studies were performed preoperatively, a month and a year postoperatively. The clinical assessment was done by the Fligelstone scale. RESULTS: The baseline CEAP clinical classification was: 58% C2, 26% C3 and 15% C4-6. The new strategy was applied to all cases. Complications: 3 haematomas, 7 cases of asymptomatic partial anterior saphenous thrombosis. Reduction of the initial average diameter was from 6.4 mm anterior saphenous to 3.4 mm by one year (p < 0.001). At twelve months a forward flow is maintained in 82% of cases. Recurrence of varicose veins was 8%. All patients improved their clinical status based on the Fligelstone scale. Cases with saphenous diameter bigger than 7.5 mm and obesity were identified as predictors of worse clinical and hemodynamic outcome. CONCLUSIONS: This modified surgical strategy for anterior saphenous varicose veins results in better clinical outcomes at one year postoperatively


Asunto(s)
Humanos , Masculino , Femenino , Várices/cirugía , Vena Safena/cirugía , Hemodinámica/fisiología , Hematoma/complicaciones , Trombosis/complicaciones , Insuficiencia Venosa/complicaciones , Insuficiencia Venosa/cirugía , Evaluación de Resultados de Intervenciones Terapéuticas , Eficacia/métodos , Eficacia/normas , Resultado del Tratamiento , Evaluación de Eficacia-Efectividad de Intervenciones , Estudios Prospectivos , Várices/complicaciones , Várices/fisiopatología
10.
J Vasc Surg ; 43(5): 1064-7, 2006 May.
Artículo en Inglés | MEDLINE | ID: mdl-16678708

RESUMEN

We report a new procedure for embolization of hypogastric arteries simultaneously with aortoiliac stenting. Eight patients with aortoiliac (n = 6) and iliac (n = 2) aneurysms have been treated with this procedure. The technique involves the placement of a hook catheter near the hypogastric artery or in the sac, and the endoprosthesis insertion is done by using the same arteriotomy. The endoprosthesis is deployed and the coil is released. Saline is injected into the sac. The catheter is removed and the balloon at the distal end of the endoprosthesis is inflated. Computed tomography images showed periprosthesis or aneurysm thrombosis. No endoleaks or coils displacement in the sac were found.


Asunto(s)
Angioplastia/instrumentación , Aneurisma de la Aorta Abdominal/cirugía , Implantación de Prótesis Vascular/instrumentación , Embolización Terapéutica/instrumentación , Aneurisma Ilíaco/cirugía , Pelvis/irrigación sanguínea , Stents , Aneurisma de la Aorta Abdominal/diagnóstico por imagen , Circulación Colateral/fisiología , Terapia Combinada , Comorbilidad , Estudios de Seguimiento , Humanos , Aneurisma Ilíaco/diagnóstico por imagen , Diseño de Prótesis , Tomografía Computarizada por Rayos X
11.
Angiología ; 58(4): 295-301, jul.-ago. 2006.
Artículo en Es | IBECS (España) | ID: ibc-048029

RESUMEN

Objetivo. Valorar los resultados preliminares obtenidos en nuestro servicio en revascularización infragenicular con aloinjerto arterial criopreservado (AAC) en caso de ausencia de injerto autólogo. Pacientes y métodos. Entre junio de 2001 y agosto de 2005, realizamos ocho procedimientos en ocho pacientes (dos mujeres y seis varones) con una edad media de 73 años (rango: 55-82 años). En dos casos los injertos fueron compuestos AAC-segmento venoso residual. En otros dos casos se emplearon dos AAC. Las indicaciones para intervenir fueron isquemia crítica (siete) e infección protésica (uno). En cinco casos había al menos una revascularización previa. Los AAC se obtuvieron de donante cadáver. La anastomosis distal se realizó sobre poplítea (dos), arteria tibial (cinco) o arteria perimaleolar (uno). En todos los casos se descartó la existencia de segmento venoso autólogo suficiente mediante eco-Doppler. El seguimiento fue clínico y ecográfico. Resultados. Durante el primer mes se produjeron una rotura de AAC y una trombosis precoz, ambas con reparación satisfactoria. Durante un seguimiento medio de 14 meses (rango: 1-46 meses), cuatro injertos sufrieron un fallo primario: dos trombosis, una estenosis y una degeneración aneurismática. Ello derivó en una amputación mayor, una trombectomía y una sustitución del injerto. La permeabilidad global fue del 75% (6/8) y la salvación de extremidad del 87,5% (7/8). Una paciente falleció a los cuatro y otro a los 46 meses, ambos con injerto permeable. Conclusión. A pesar de ser una serie pequeña, los AAC pueden ser una opción en las revascularizaciones infrageniculares en caso de ausencia de injerto autólogo suficiente para ésta


Aim. To assess our preliminary results of infrapopliteal bypass grafting performed with cryopreserved arterial allografts (CAA) in case of absence of alternate autologous veins. Patients and methods. Between June 2001 and August 2005, eight procedures were performed in eight patients (two female and six male), with a mean age of 73 years (range: 55-82 years). In two cases a composite CAA-residual vein bypass was realized. In another two cases two segments of CAA were used. Indications for operation were critical leg ischaemia in seven cases and infection in the other. In five cases, there was at least one previous revascularization on the same limb. CAA were obtained from cadaveric donors in a multidisciplinary organs explant program. Distal anastomosis was to the bellow knee popliteal artery in two cases, to a tibial artery in five cases and to a perimaleolar artery in one case. In all cases we searched for the existence of alternate autologous vein with Doppler scan. The surveillance was clinic and with Doppler scan. Results. During follow-up (mean: 14 months; range: 1-46 months), four grafts failed. These failures were two thrombosis, one stenosis and one aneurysmatic degradation. Due to this, a major amputation and a CAA-prosthetic replacement were performed. The global patency rate was 75% (6/8) and the limb salvage rate was 87.5% (7/8). One patient died at four month after procedure, with patent bypass. Conclusion. Even knowing that this is a small group of patients, we think CAA could be an option in infrapopliteal bypass surgery in case of absence of autologous vein


Asunto(s)
Masculino , Femenino , Persona de Mediana Edad , Humanos , Revascularización Miocárdica/métodos , Trasplante Homólogo/métodos , Criopreservación/métodos , Inhibidores de Agregación Plaquetaria/uso terapéutico , Trombosis/complicaciones , Trombosis/diagnóstico , Criopreservación , Comorbilidad , Estudios Prospectivos , Anastomosis Quirúrgica , Estudios Retrospectivos
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