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1.
Osteoarthritis Cartilage ; 27(1): 49-58, 2019 01.
Artículo en Inglés | MEDLINE | ID: mdl-30243947

RESUMEN

OBJECTIVES: Pain sensitization could be a risk factor for poor outcomes after knee replacement surgery (KR) for knee osteoarthritis (KOA). We aimed to evaluate the association between pre-operative central and peripheral pain sensitization measured using a digital pressure algometer and KR outcomes. METHODS: Consecutive patients with severe KOA listed for KR were recruited. Sociodemographic and symptoms data were collected prior to surgery. Pre-operative pressure pain thresholds (PPTs) were measured using a digital pressure algometer at the index knee and forearm. Patient satisfaction at 6 and 12 months after KR was assessed using a 4-point Likert scale, and dichotomized to satisfied and dissatisfied to KR. Western Ontario and McMaster Universities Index (WOMAC) Pain and function was assessed. The associations between pre-operative PPTs with KR outcomes at 6 and 12 months were evaluated. RESULTS: Of the 243 patients recruited, response rate at 6 and 12 months were 95.5% and 96.7%. The dissatisfaction rates were 8.2% and 5.1% at 6 and 12 months. There was no statistically significant association between pre-operative index knee or forearm PPTs and patient satisfaction. PPTs measured at the knee, but not the forearm, were weakly associated with change in the WOMAC pain score at 12 months, after adjustment for confounding factors. CONCLUSION: Pre-operative central sensitization, measured by handheld digital algometry, was not statistically significantly associated with satisfaction or change in pain after KR. Pre-operative peripheral sensitization was associated with change in pain symptoms after KR; however, this association was weak and unlikely to be a meaningful predictor of KR outcome in clinical practice.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Osteoartritis de la Rodilla/cirugía , Umbral del Dolor/fisiología , Dolor/etiología , Anciano , Sensibilización del Sistema Nervioso Central/fisiología , Estudios de Cohortes , Femenino , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/complicaciones , Dimensión del Dolor/métodos , Satisfacción del Paciente , Periodo Preoperatorio , Índice de Severidad de la Enfermedad , Resultado del Tratamiento
2.
Knee Surg Sports Traumatol Arthrosc ; 25(3): 639-644, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-25466278

RESUMEN

Purpose Patients with severe deformity beyond the standard indications for unicompartmental knee arthroplasty (UKA) may be suitable and benefit from UKA. This study investigated their outcomes to determine whether good function and quality of life (QOL) can be achieved. MATERIALS AND METHODS: Fifty-three patients with severe deformity (40 patients with FFD ≥15° and 13 patients with varus deformity ≥15°, Group A) were matched with 53 patients with less severe deformities who underwent UKA (Group B/controls) in terms of age, sex, BMI and duration of follow-up. Their flexion range, Knee Society scores (KSS), Oxford knee scores (OKS) and SF-36 QOL scores were analysed pre-operatively and at 2 years. RESULTS: Group A patients were largely similar to Group B patients pre-operatively in terms of maximum flexion angle, OKS and SF-36 scores except for knee score and mental health component of SF-36. At 2 years, Group A reported largely similar results compared with Group B in all outcome scores (OKS, KSS, SF-36) and flexion angle. Post-operative mechanical alignment was better for the control group though it is not statistically significant. There were no revisions in the patients with severe pre-operative deformity at 5 years post-operatively. (Survivorship 100 % at 5 years). CONCLUSION: Selected patients with severe deformity can achieve good function and QOL with UKA if satisfactory mechanical alignment is restored. This study supports a broadening of the indications of UKA; however, further follow-up is needed to assess the longer-term durability of the operation. LEVEL OF EVIDENCE: IV.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/métodos , Genu Varum/cirugía , Deformidades Adquiridas de la Articulación/cirugía , Osteoartritis de la Rodilla/cirugía , Femenino , Humanos , Articulación de la Rodilla/cirugía , Prótesis de la Rodilla , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Calidad de Vida , Rango del Movimiento Articular , Resultado del Tratamiento
3.
Anaesth Intensive Care ; 44(3): 428-9, 2016 May.
Artículo en Inglés | MEDLINE | ID: mdl-27246948
4.
Br J Anaesth ; 105(3): 371-6, 2010 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-20573635

RESUMEN

BACKGROUND: Multimodal analgesia is advocated for perioperative pain management to reduce opioid use and its associated adverse effects. Serotonin and norepinephrine are involved in the modulation of endogenous analgesic mechanisms via descending inhibitory pain pathways in the brain and spinal cord. An increase in serotonin and norepinephrine may increase inhibition of nociceptive input and improve pain relief. Duloxetine, a selective serotonin and norepinephrine reuptake inhibitor, has demonstrated efficacy in chronic pain conditions such as painful diabetic neuropathy and post-herpetic neuralgia. The objective of the study was to evaluate the efficacy of duloxetine in reducing morphine requirements in patients after knee replacement surgery. METHODS: Fifty patients received either two doses of oral duloxetine 60 mg (2 h before surgery and on first postoperative day) or placebo. All patients received patient-controlled analgesia with morphine for 48 h after operation. Pain and adverse effects were assessed at 0.5, 1, 2, 6, 12, 24, and 48 h after surgery on an 11-point numeric rating scale. RESULTS: Twenty-three patients in the duloxetine group and 24 patients in the placebo group completed the study. Morphine requirements during the 48 h after surgery were significantly lower in the duloxetine group [19.5 mg, standard deviation (sd) 14.5 mg] compared with the placebo group (30.3 mg, sd 18.1 mg) (P=0.017). There were no statistically significant differences between the groups in pain scores (at rest and on movement) or in adverse effects. CONCLUSIONS: Perioperative administration of duloxetine reduced postoperative morphine requirements during the first 48 h after knee replacement surgery, without significant adverse effects.


Asunto(s)
Analgésicos Opioides/administración & dosificación , Artroplastia de Reemplazo de Rodilla , Morfina/administración & dosificación , Dolor Postoperatorio/prevención & control , Tiofenos/administración & dosificación , Adolescente , Inhibidores de Captación Adrenérgica/administración & dosificación , Inhibidores de Captación Adrenérgica/efectos adversos , Adulto , Anciano , Analgesia Controlada por el Paciente/métodos , Analgésicos Opioides/efectos adversos , Método Doble Ciego , Quimioterapia Combinada , Clorhidrato de Duloxetina , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Morfina/efectos adversos , Dimensión del Dolor/métodos , Cuidados Posoperatorios/métodos , Inhibidores Selectivos de la Recaptación de Serotonina/administración & dosificación , Inhibidores Selectivos de la Recaptación de Serotonina/efectos adversos , Tiofenos/efectos adversos , Adulto Joven
5.
Malays Orthop J ; 14(3): 73-81, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-33403065

RESUMEN

INTRODUCTION: This study aims to investigate whether patients undergoing two-stage revision total hip arthroplasty (THA) for prosthetic joint infection (PJI) and one-stage revision THA for aseptic reasons have similar clinical outcomes and patient satisfaction during their post-operative follow-up. We hypothesise that the two-stage revision THA for PJI is associated with poorer outcomes as compared to aseptic revision THA. MATERIALS AND METHODS: We reviewed prospectively collected data in our tertiary hospital arthroplasty registry and identified patients who underwent revision THA between 2001 and 2014, with a minimum of two years follow-up. The study group (two-stage revision THA for PJI) consists of 23 patients and the control group (one-stage revision THA for aseptic reasons) consists of 231 patients. Patient demographics, Western Ontario and McMaster Universities Arthritis Index (WOMAC), Oxford Hip Score (OHS), Short Form-36 (SF-36) scores and patient reported satisfaction were evaluated. Student's t-test was used to compare continuous variables between the two groups. Statistical significance was defined as p <0.05. RESULTS: The pre-operative demographics and clinical scores were relatively similar between the two groups of patients. At two years, patients who underwent revision THA for PJI reported a better WOMAC Pain Score and OHS as compared to aseptic revision THA. A similar proportion of patients were satisfied with their results of surgery in both groups (p=0.093). CONCLUSIONS: Although patients who underwent revision THA for PJI had poorer pre-operative functional scores (WOMAC function and SF-36 PF), at two years follow-up, these two groups of patients have comparable post-operative outcomes. Interestingly, patients who had revision THA for PJI reported a better clinical outcome in terms of OHS and WOMAC Pain score as compared to the aseptic group. We conclude that the revision THA for PJI is not inferior to aseptic revision THA in terms of patient satisfaction and clinical outcomes.

6.
Osteoarthritis Cartilage ; 17(9): 1163-9, 2009 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-19409293

RESUMEN

OBJECTIVES: Use Rasch analysis to examine the psychometric properties of the Oxford Knee Score (OKS), particularly in respect to unidimensionality, and consistency of item functioning before and after total knee replacement and across age and gender groups. METHODS: The 12-item OKS was administered to 1,712 patients before the surgery, and 1,322 and 855 patients were administered the instrument repeatedly at the 6-month and 2-year postoperative assessments, respectively. Data were fitted to the Rasch partial credit model with the Winsteps program. Differential item functioning (DIF) analysis was performed, and fit statistics in combination with principal components analysis of the residuals were used to test the unidimensionality assumption. The fit criteria were set at 1.5 and 2.0 for infit mean-square (MNSQ) and outfit MNSQ, respectively. RESULTS: At baseline, item difficulty ranged from -1.86 to 1.78 logits, and person measures had a mean+/-SD of -0.01+/-0.89. Misfit items were "limping" and "night pain" in preoperative data and "limping" and "kneeling" in postoperative data. After removing items limping and kneeling and recoding item night pain, none of the items misfit at each of the time points and there was stability of item difficulty ordering across time. In the modified OKS set, five items displayed DIF by age and three by gender. CONCLUSION: The original OKS had adequate targeting and good coverage of knee severity levels in preoperative patients. The modified 10-item OKS data fit the Rasch model and had stable item difficulty ordering over time.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/psicología , Osteoartritis de la Rodilla/cirugía , Actividades Cotidianas , Factores de Edad , Anciano , Anciano de 80 o más Años , Comparación Transcultural , Evaluación de la Discapacidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/psicología , Dimensión del Dolor/psicología , Calidad de Vida , Índice de Severidad de la Enfermedad , Factores Sexuales , Encuestas y Cuestionarios/normas
7.
J Orthop Surg (Hong Kong) ; 17(1): 1-5, 2009 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-19398783

RESUMEN

PURPOSE: To compare the efficacy and safety of different modes of thromboembolic prophylaxis for elective total knee arthroplasty (TKA) in Asian patients. METHODS: 440 low-risk patients undergoing TKA were randomised into 4 equal groups: (1) no prophylaxis (control), (2) graduated compression stockings (GCS), (3) intermittent pneumatic compression (IPC), and (4) low-molecular-weight heparin (enoxaparin). Duplex ultrasonography was used as an assessment tool. RESULTS: The deep vein thrombosis point prevalence was highest in the control group (22%), which was significantly higher than in patients receiving IPC (8%, p=0.032) or enoxaparin (6%, p=0.001). One patient each in the control and GCS groups developed a non-fatal pulmonary embolism. Patients on enoxaparin received more blood transfusions and 2 of them had major bleeding complications. CONCLUSION: IPC is the preferred method of thromboprophylaxis for TKA in Asian patients.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/efectos adversos , Pueblo Asiatico , Enoxaparina/uso terapéutico , Fibrinolíticos/uso terapéutico , Aparatos de Compresión Neumática Intermitente , Medias de Compresión , Tromboembolia/prevención & control , Anciano , Anciano de 80 o más Años , Femenino , Hong Kong , Humanos , Masculino , Persona de Mediana Edad , Tromboembolia/etnología , Tromboembolia/etiología , Resultado del Tratamiento
8.
Bone Joint J ; 101-B(2): 213-220, 2019 02.
Artículo en Inglés | MEDLINE | ID: mdl-30700121

RESUMEN

AIMS: The aim of this study was to assess the influence of obesity on the clinical outcomes and survivorship ten years postoperatively in patients who underwent a fixed-bearing unicompartmental knee arthroplasty (UKA). PATIENTS AND METHODS: We prospectively followed 184 patients who underwent UKA between 2003 and 2007 for a minimum of ten years. A total of 142 patients with preoperative body mass index (BMI) of < 30 kg/m2 were in the control group (32 male, 110 female) and 42 patients with BMI of ≥ 30 kg/m2 were in the obese group (five male, 37 female). Pre- and postoperative range of movement (ROM), Knee Society Score (KSS), Oxford Knee Score (OKS), 36-Item Short-Form Health Survey (SF-36), and survivorship were analyzed. RESULTS: Patients in the obese group underwent UKA at a significantly younger mean age (56.5 years (sd 6.4)) than those in the control group (62.4 years (sd 7.8); p < 0.001). There was no significant difference in preoperative functional scores. However, those in the obese group had a significantly lower ROM (116° (sd 15°) vs 123° (sd 17°); p = 0.003). Both groups achieved significant improvement in outcome scores regardless of BMI, ten years postoperatively. All patients achieved the minimal clinically important difference (MCID) for OKS and KSS. Both groups also had high rates of satisfaction (96.3% in the control group and 97.5% in the obese group) and the fulfilment of expectations (94.9% in the control group and 95.0% in the obese group). Multiple linear regression showed a clear association between obesity and a lower OKS two years postoperatively and Knee Society Function Score (KSFS) ten years postoperatively. After applying propensity matching, obese patients had a significantly lower KSFS, OKS, and physical component score (PCS) ten years postoperatively. Seven patients underwent revision to total knee arthroplasty (TKA), two in the control group and five in the obese group, resulting in a mean rate of survival at ten years of 98.6% and 88.1%, respectively (p = 0.012). CONCLUSION: Both groups had significant improvements in functional and quality-of-life scores postoperatively. However, obesity was a significant predictor of poorer improvement in clinical outcome and an increased rate of revision ten years postoperatively.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Prótesis de la Rodilla , Obesidad/complicaciones , Osteoartritis de la Rodilla/cirugía , Factores de Edad , Anciano , Artroplastia de Reemplazo de Rodilla/instrumentación , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/complicaciones , Satisfacción del Paciente , Estudios Prospectivos , Diseño de Prótesis , Falla de Prótesis , Calidad de Vida , Rango del Movimiento Articular , Recuperación de la Función , Reoperación , Resultado del Tratamiento
9.
Scand J Rheumatol ; 37(6): 450-61, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18666026

RESUMEN

OBJECTIVE: To validate the International Classification of Functioning, Disability, and Health (ICF) Brief Core Set for osteoarthritis (OA) by comparing the preliminary Brief Core Set to a selection of categories from the Comprehensive Core Set that explain most of the variance of functioning and health. METHODS: Patients with knee OA were asked to complete the Case Report Form for Patients, which includes the 36-item Short Form Health Survey (SF-36) and the Self-administered Comorbidity Questionnaire (SCQ). For each patient, the research staff was asked to complete the Case Report Form for Health Professionals, which includes the ICF Comprehensive Core Set for OA. Two individual questions regarding patients' general health and functioning were completed by both the patients and the research staff. The ICF categories to be entered into an initial regression model were selected following systematic steps in accordance with the ICF structure. Based on the initial models, additional models were generated by systematically substituting the ICF categories included in the initial models with other highly intercorrelated categories. RESULTS: A consecutive sample of 122 patients completed this study. Sixteen candidate ICF categories were identified by 15 linear regression models, which accounted for 5.5-57.7% of the total variance. Besides the two categories, b710 and b730, that are already included in the preliminary Brief Core Set, 14 additional categories were identified to be potential candidates for the Core Set. CONCLUSIONS: This study complemented the development of the Brief Core Set, which should be further refined by incorporating the opinions of patients, clinicians, and statisticians.


Asunto(s)
Osteoartritis de la Rodilla/clasificación , Osteoartritis de la Rodilla/fisiopatología , Índice de Severidad de la Enfermedad , Anciano , Estudios Transversales , Evaluación de la Discapacidad , Femenino , Humanos , Clasificación Internacional de Enfermedades , Modelos Lineales , Masculino , Encuestas y Cuestionarios
10.
J Bone Joint Surg Br ; 90(6): 738-44, 2008 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-18539666

RESUMEN

We have performed a prospective double-blind, randomised controlled trial over two years to evaluate the efficacy and safety of an intra-operative peri-articular injection of triamcinolone acetonide in patients undergoing medial unicondylar knee replacement. We randomised 90 patients into two equal groups. The study group received an injection of triamcinolone acetonide, bupivacaine, and epinephrine into the peri-articular tissues at the end of the operation. The control group received the same injection mixture but without the addition of triamcinolone. The peri-operative analgesic regimen was standardised. The study group reported a significant reduction in pain (p = 0.014 at 12 hours, p = 0.031 at 18 hours and p = 0.031 at 24 hours) and had a better range of movement (p = 0.023 at three months). There was no significant difference in the rate of infection and no incidence of tendon rupture in either group. The addition of corticosteroid to the peri-articular injection after unicondylar knee replacement had both immediate and short-term benefits in terms of relief from pain, and rehabilitation with no increased risk of infection.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/métodos , Glucocorticoides/administración & dosificación , Dolor Postoperatorio/prevención & control , Triamcinolona Acetonida/administración & dosificación , Anciano , Anciano de 80 o más Años , Analgésicos Opioides/administración & dosificación , Artroplastia de Reemplazo de Rodilla/rehabilitación , Método Doble Ciego , Esquema de Medicación , Femenino , Humanos , Inyecciones Intraarticulares , Cuidados Intraoperatorios/métodos , Articulación de la Rodilla/fisiopatología , Masculino , Persona de Mediana Edad , Morfina/administración & dosificación , Dimensión del Dolor/métodos , Estudios Prospectivos , Rango del Movimiento Articular , Resultado del Tratamiento
11.
Bone Joint J ; 100-B(5): 579-583, 2018 05 01.
Artículo en Inglés | MEDLINE | ID: mdl-29701098

RESUMEN

Aims: This study investigated the influence of body mass index (BMI) on patients' function and quality of life ten years after total knee arthroplasty (TKA). Patients and Methods: A total of 126 patients who underwent unilateral TKA in 2006 were prospectively included in this retrospective study. They were categorized into two groups based on BMI: < 30 kg/m2 (control) and ≥ 30 kg/m2 (obese). Functional outcome was assessed using the Knee Society Function Score (KSFS), Knee Society Knee Score (KSKS), and Oxford Knee Score (OKS). Quality of life was assessed using the Physical (PCS) and Mental Component Scores (MCS) of the 36-Item Short-Form Health Survey. Results: Results Patients in the obese group underwent TKA at a younger age (mean, 63.0 years, sd 8.0) compared with the control group (mean, 65.6 years, sd 7.6; p = 0.03). Preoperatively, both groups had comparable functional and quality-of-life scores. Ten years postoperatively, the control group had significantly higher OKS and MCS compared with the obese group (OKS, mean 18 (sd 5) vs mean 22 (sd 10), p = 0.03; MCS, mean 56 (sd 10) vs mean 50 (sd 11), p = 0.01). After applying multiple linear regression with the various outcomes scores as dependent variables and age, gender, and Charlson Comorbidity Index as independent variables, there was a clear association between obesity and poorer outcome in KSFS, OKS, and MCS at ten years postoperatively (p < 0.01 in both KSFS and OKS, and p = 0.03 in MCS). Both groups had a high satisfaction rate (97.8% in the control group vs 87.9% in the obese group, p = 0.11) and fulfillment of expectations at ten years (98.9% in the control group vs 100% in the obese group, p = 0.32). Conclusion: Although both obese and non-obese patients have significant improvements in function and quality of life postoperatively, obese patients tend to have smaller improvements in the OKS and MCS ten years postoperatively. It is important to counsel patients on the importance of weight management to achieve a more sustained outcome after TKA. Cite this article: Bone Joint J 2018;100-B:579-83.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Obesidad/complicaciones , Osteoartritis de la Rodilla/cirugía , Anciano , Índice de Masa Corporal , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/complicaciones , Calidad de Vida , Recuperación de la Función , Estudios Retrospectivos , Resultado del Tratamiento
12.
Bone Joint J ; 99-B(10): 1329-1334, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28963154

RESUMEN

AIMS: Little is known about the relative outcomes of revision of unicompartmental knee arthroplasty (UKA) and high tibial osteotomy (HTO) to total knee arthroplasty (TKA). The aim of this study is to compare the outcomes of revision surgery for the two procedures in terms of complications, re-revision and patient-reported outcome measures (PROMs) at a minimum of two years follow-up. PATIENTS AND METHODS: This study was a retrospective review of data from an institutional arthroplasty registry for cases performed between 2001 and 2014. A total of 292 patients were identified, of which 217 had a revision of HTO to TKA, and 75 had revision of UKA to TKA. While mean follow-up was longer for the HTO group compared with the UKA group, patient demographics (age, body mass index and Charlson co-morbidity index) and PROMs (Short Form-36, Oxford Knee Score, Knee Society Score, both objective and functional) were similar in the two groups prior to revision surgery. Outcomes included the rate of complications and re-operation, PROMS and patient-reported satisfaction at six months and two years post-operatively. We also compared the duration of surgery and the need for revision implants in the two groups. RESULTS: At two-year follow-up, both groups of patients had made significant improvement in terms of PROMs compared with pre-operative scores. PROMs and satisfaction rates were similar in the two groups. Complications requiring re-operation were significantly more frequent in the HTO group whilst more revision implants were used in the UKA group, resulting in a longer operative duration. CONCLUSION: Revision of HTO and UKA achieve similar post-operative PROMs and satisfaction. Revision of UKA more frequently requires revision components with increased operation duration but fewer complications requiring re-operation compared with revision of HTO. Cite this article: Bone Joint J 2017;99-B:1329-34.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/métodos , Articulación de la Rodilla/fisiopatología , Osteoartritis de la Rodilla/cirugía , Osteotomía/efectos adversos , Resultado del Tratamiento , Anciano , Femenino , Estudios de Seguimiento , Humanos , Articulación de la Rodilla/cirugía , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/fisiopatología , Satisfacción del Paciente , Rango del Movimiento Articular , Sistema de Registros , Reoperación , Estudios Retrospectivos , Factores de Tiempo , Insuficiencia del Tratamiento
13.
Bone Joint J ; 98-B(6): 780-5, 2016 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-27235520

RESUMEN

AIMS: This study investigated the influence of body mass index (BMI) on the post-operative fall in the level of haemoglobin (Hb), length of hospital stay (LOS), 30-day re-admission rate, functional outcome and quality of life, two years after total knee arthroplasty (TKA). PATIENTS AND METHODS: A total of 7733 patients who underwent unilateral primary TKA between 2001 and 2010 were included. The mean age was 67 years (30 to 90). There were 1421 males and 6312 females. The patients were categorised into three groups: BMI < 25.0 kg/m(2) (normal); BMI between 25.0 and 39.9 kg/m(2) (obese); and BMI ≥ 40.0 kg/m(2) (morbidly obese). RESULTS: Compared with the normal and obese groups, the mean LOS was longer by one day (95% confidence interval (CI) 0 to 2) in the morbidly obese group (p = 0.003 and p = 0.001 respectively). The 30-day re-admisison rate was also higher in the morbidly obese group compared to the obese group (OR 2.323, 95% CI 1.101 to 4.900, p = 0.024); and showed a higher trend compared to the normal group (OR 1.850, 95% CI 0.893 to 3.831, p = 0.100). However, the morbidly obese group had a smaller drop in post-operative Hb level by a mean of 0.5 g/dl (0.3 to 0.6) and 0.3 g/dl (0.1 to 0.5), when compared with the normal and obese groups respectively (both p < 0.001). Furthermore, the mean improvement in Oxford Knee Score (OKS) and Knee Society Knee Score (KSKS) at two years follow-up was three points (two to four) and five points (two to seven) more in the morbidly obese group than in the normal group (both p < 0.001). The mean improvement in Knee Society Function Score, and Physical and Mental Component Scores of Short Form-36 were comparable between the three BMI groups (p = 0.736, p = 0.739 and p = 0.731 respectively). The ten-year rate of survival was 98.8% (98.0 to 99.3), 98.9% (98.5 to 99.2) and 98.0% (95.8 to 100), for the normal, obese and morbidly obese groups, respectively (p = 0.703). CONCLUSION: Although morbidly obese patients have a longer LOS and higher 30-day re-admission rate after TKA, they have a smaller drop in post-operative Hb level and larger improvement in OKS and KSKS at two years follow-up. The ten-year rate of survival of TKA was also comparable with those with a normal BMI. TAKE HOME MESSAGE: Morbidly obese patients should not be excluded from the benefits of TKA. Cite this article: Bone Joint J 2016;98-B:780-5.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Índice de Masa Corporal , Calidad de Vida , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Hemoglobinas/análisis , Humanos , Tiempo de Internación/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Obesidad/epidemiología , Obesidad Mórbida/epidemiología , Readmisión del Paciente/estadística & datos numéricos , Complicaciones Posoperatorias , Estudios Retrospectivos , Singapur/epidemiología
14.
Crit Rev Biomed Eng ; 28(1-2): 33-40, 2000.
Artículo en Inglés | MEDLINE | ID: mdl-10999362

RESUMEN

In designing a total knee replacement (TKR) prosthesis catering for the Asian population, 62 sets of femur were harvested and analyzed. The morphometrical data obtained were found to be in good agreement with dimensions typical of the Asian knee and has reaffirmed the fact that Caucasian knees are generally larger than Asian knees. Subsequently, these data when treated using a multivariate statistical technique resulted in the establishment of major design parameters for six different sizes of femoral implants. An extra-small implant size with established dimensions and geometrical shape has surfaced from the study. The differences between the Asian knees and the Caucasian knees are discussed. Employing the established femoral dimensions and motion path of the knee joint, the articulating tibia profile was generated. All the sizes of implants were modeled using a computer-aided software package. Thereupon, these models that accurately fits the local Asian knee were transported into a dynamic and kinematic analysis software package. The tibiofemoral joint was modeled successfully as a slide curve joint to study intuitively the motion of the femur when articulating on the tibia surface. An optimal tibia profile could be synthesized to mimic the natural knee path motion. Details of the analysis are presented and discussed.


Asunto(s)
Pueblo Asiatico , Articulación de la Rodilla/anatomía & histología , Articulación de la Rodilla/fisiología , Prótesis de la Rodilla , Anciano , Anciano de 80 o más Años , Asia , Fenómenos Biomecánicos , Cadáver , Simulación por Computador , Características Culturales , Fémur/anatomía & histología , Humanos , Persona de Mediana Edad , Movimiento (Física) , Análisis Multivariante , Singapur , Programas Informáticos , Tibia/anatomía & histología , Población Blanca
15.
Proc Inst Mech Eng H ; 214(3): 301-9, 2000.
Artículo en Inglés | MEDLINE | ID: mdl-10902444

RESUMEN

This paper describes the work that leads to the establishment of a set of major parameters for the design of symmetrical prosthetic implants for the Asian population. In the study, 62 sets of femurs harvested from cadavers were used. The morphometrical data obtained are compared with known results and found to be in good agreement with Asian knees. Subsequently, the data are treated and analysed using the principal component analysis, a statistical technique for analysing multivariate data. The analysis has resulted in the establishment of the major design parameters for six different sizes of femoral implants. Details of the analysis are presented. The major parameters obtained in this work are compared with those of existing implants. Results of the comparison are presented. The relationship between the anterio-posterior and medio-lateral dimensions is also examined and reported.


Asunto(s)
Fémur/anatomía & histología , Prótesis de la Rodilla , Diseño de Prótesis , Anciano , Pueblo Asiatico , Cadáver , Femenino , Humanos , Masculino , Persona de Mediana Edad , Población Blanca
16.
Singapore Med J ; 33(4): 355-8, 1992 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-1411663

RESUMEN

A retrospective study of the results of operative treatment of 60 long bones secondaries in 46 patients was carried out. The mean period of follow-up was 10 months. The most common primary in this study was carcinoma of the breast (28.2%), followed by carcinoma of the lung (21.7%) and unknown primary (10.9%). Three groups of patients were studied--pathological fracture group, prophylactic fixation group and a mixed group. In the pathological fracture group, 70% of patients achieved good to excellent pain relief and 60.9% was able to walk with or without walking aids. In the prophylactic group, all the patients achieved good to excellent pain relief and 60% were able to ambulate with or without walking aids. In the mixed group, all the patients achieved good to excellent pain relief and 66.6% of the patients were able to walk with aids. The operative mortality in both the pathological fracture group and prophylactic fixation group was 10% and 33.3% in the mixed group. Multiple internal fixation performed at one operative session was associated with high operative mortality (50%).


Asunto(s)
Neoplasias Óseas/secundario , Fijación Interna de Fracturas , Fracturas Espontáneas/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Neoplasias Óseas/cirugía , Neoplasias de la Mama/cirugía , Femenino , Estudios de Seguimiento , Humanos , Neoplasias Pulmonares/cirugía , Masculino , Persona de Mediana Edad , Neoplasias Primarias Desconocidas/cirugía , Estudios Retrospectivos
17.
Singapore Med J ; 37(4): 443-5, 1996 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-8993153

RESUMEN

We report an unusual case of a popliteal aneurysm complicating a distal femoral osteochondroma caused by the repeated massages of a traditional medicine practitioner (sinseh). Management was by excision of the exostosis and reconstruction of the damaged arterial segment by a reversed long saphenous vein graft. We advice against massage over an osteochondroma on the distal medial aspect of the femur and suggest prophylactic removal of such lesions because of this potential complication.


Asunto(s)
Aneurisma Falso/etiología , Neoplasias Óseas/terapia , Masaje/efectos adversos , Medicina Tradicional , Osteocondroma/terapia , Arteria Poplítea , Adolescente , Aneurisma Falso/cirugía , Angiografía , Neoplasias Óseas/diagnóstico , Neoplasias Óseas/cirugía , Humanos , Masculino , Osteocondroma/diagnóstico , Osteocondroma/cirugía
18.
Singapore Med J ; 37(1): 69-71, 1996 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-8783918

RESUMEN

The image intensifier is now commonly used in orthopaedic surgery for intraoperative assessment of fracture reduction and implant placement, especially with the increasing trend toward use of closed nailing devices. We conducted a study using lithium fluoride chips to measure the radiation dosage to the surgeon and the operating theatre personnel. Over a 6-month period we measured the cumulative radiation dosage over the eyes (0.83mSv), thyroid (with shield 0.51mSv, without 0.79mSv), waist (with apron 0.48mSv, without 0.86mSv), hands (right 0.7mSv, left 0.14mSv) and feet (0.62 mSv). These values were well within the ICRP safety guidelines. The use of protective lead shielding was effective in reducing radiation dosage to operators. A survey of the operating theatre area using a radiation counter showed that radiation scatter to OT personnel was low. This study hopes to allay the fears that use of the image intensifier is hazardous to OT personnel.


Asunto(s)
Exposición Profesional/análisis , Ortopedia , Dosis de Radiación , Intensificación de Imagen Radiográfica , Dispersión de Radiación , Dosimetría Termoluminiscente , Fluoruros , Fluoroscopía , Humanos , Compuestos de Litio , Concentración Máxima Admisible , Exposición Profesional/prevención & control , Fantasmas de Imagen , Protección Radiológica
19.
Singapore Med J ; 44(11): 559-62, 2003 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-15007494

RESUMEN

Fifty consecutive patients with isolated medial compartmental osteoarthritis of the knee were treated with minimally invasive unicompartmental knee arthroplasty (UKA). An equal number of patients with total knee arthroplasty (TKA) performed in the same period were selected and matched with respect to age, pre-operative range of motion and radiological grade of knee arthrosis. Both groups of patients were prospectively followed up. Comparison of the two groups at six months show that patients with minimally invasive UKA have less blood loss, quicker rehabilitation, earlier ambulation, shorter hospitalisation stay and better post-operative range-of-motion with reduced hospitalisation cost. Reflecting on a six-month follow-up and immediate post-operative events, we conclude that minimally invasive UKA is a relatively more cost effective procedure than TKA for these patients.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/métodos , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Osteoartritis de la Rodilla/cirugía , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Rango del Movimiento Articular , Resultado del Tratamiento
20.
Singapore Med J ; 41(1): 6-8, 2000 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-10783672

RESUMEN

BACKGROUND/AIM OF STUDY: The results of primary total knee arthroplasties have improved over the years but some still fail, requiring revision. Revision total knee arthroplasty is technically more difficult and has not enjoyed the same success rates as the index operation. The aim of this retrospective study was to review the results of revision total knee arthroplasties carried out at our centre. This is the first study in Singapore on revision total knee arthroplasty. METHODS: A retrospective study where 17 patients (18 knees) had been followed up since their revision operations were clinically assessed. Based on the Knee Society Clinical Scoring System, they were assigned separate knee and function scores (each having a maximum possible 100). RESULTS: The mean knee score was 76 (range 35-93), which rates as good. Of the 18 knees, 67% had excellent or good knee scores. By comparison, the mean function score was 56 (range 0-90) which rates as poor and 33% had excellent or good function scores. CONCLUSION: Revision total knee arthroplasty achieves good and excellent results in spite of technical difficulties often associated with the revision operation. The difference in mean knee and function scores emphasises that many other factors such as physical strength and stamina affect function. Nevertheless, 15 patients were able to walk out of their house and around their neighbourhood for varying distances. This satisfied their expectations and the poor mean function score may reflect different expectations of patients overseas from whence this scoring system originated.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Reoperación , Estudios Retrospectivos , Singapur , Resultado del Tratamiento
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