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1.

A Path Forward for Regenerative Medicine.

Fanaroff, Alexander C; Morrow, Valarie; Krucoff, Mitchell W; Seltzer, Jonathan H; Perin, Emerson C; Taylor, Doris A; Miller, Leslie W; Zeiher, Andreas M; Fernández-Avilés, Francisco; Losordo, Douglas W; Henry, Timothy D; Povsic, Thomas J.

Circ Res; 123(4): 495-505, 2018 08 03.

Artículo en Inglés | MEDLINE | ID: mdl-30355250

2.

E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells.

Xu, Shiyue; Tao, Jun; Yang, Liu; Zhang, Eric; Boriboun, Chan; Zhou, Junlan; Sun, Tianjiao; Cheng, Min; Huang, Kai; Shi, Jiawei; Dong, Nianguo; Liu, Qinghua; Zhao, Ting C; Qiu, Hongyu; Harris, Robert A; Chandel, Navdeep S; Losordo, Douglas W; Qin, Gangjian.

Circ Res; 122(5): 701-711, 2018 03 02.

Artículo en Inglés | MEDLINE | ID: mdl-29358228

3.

Angiogenic Mechanisms of Human CD34⁺ Stem Cell Exosomes in the Repair of Ischemic Hindlimb.

Mathiyalagan, Prabhu; Liang, Yaxuan; Kim, David; Misener, Sol; Thorne, Tina; Kamide, Christine E; Klyachko, Ekaterina; Losordo, Douglas W; Hajjar, Roger J; Sahoo, Susmita.

Circ Res; 120(9): 1466-1476, 2017 Apr 28.

Artículo en Inglés | MEDLINE | ID: mdl-28298297

4.

PreSERVE-AMI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Intracoronary Administration of Autologous CD34+ Cells in Patients With Left Ventricular Dysfunction Post STEMI.

Quyyumi, Arshed A; Vasquez, Alejandro; Kereiakes, Dean J; Klapholz, Marc; Schaer, Gary L; Abdel-Latif, Ahmed; Frohwein, Stephen; Henry, Timothy D; Schatz, Richard A; Dib, Nabil; Toma, Catalin; Davidson, Charles J; Barsness, Gregory W; Shavelle, David M; Cohen, Martin; Poole, Joseph; Moss, Thomas; Hyde, Pamela; Kanakaraj, Anna Maria; Druker, Vitaly; Chung, Amy; Junge, Candice; Preti, Robert A; Smith, Robin L; Mazzo, David J; Pecora, Andrew; Losordo, Douglas W.

Circ Res; 120(2): 324-331, 2017 Jan 20.

Artículo en Inglés | MEDLINE | ID: mdl-27821724

5.

Autologous CD34+ Cell Therapy for Ischemic Tissue Repair.

Sietsema, William K; Kawamoto, Atsuhiko; Takagi, Hiroshi; Losordo, Douglas W.

Circ J; 83(7): 1422-1430, 2019 06 25.

Artículo en Inglés | MEDLINE | ID: mdl-31178469

6.

Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials.

Henry, Timothy D; Losordo, Douglas W; Traverse, Jay H; Schatz, Richard A; Jolicoeur, E Marc; Schaer, Gary L; Clare, Robert; Chiswell, Karen; White, Christopher J; Fortuin, F David; Kereiakes, Dean J; Zeiher, Andreas M; Sherman, Warren; Hunt, Andrea S; Povsic, Thomas J.

Eur Heart J; 39(23): 2208-2216, 2018 06 14.

Artículo en Inglés | MEDLINE | ID: mdl-29315376

7.

Endothelial smoothened-dependent hedgehog signaling is not required for sonic hedgehog induced angiogenesis or ischemic tissue repair.

Gupta, Rajesh; Mackie, Alexander R; Misener, Sol; Liu, Lijun; Losordo, Douglas W; Kishore, Raj.

Lab Invest; 98(5): 682-691, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29453401

8.

Modulating the vascular response to limb ischemia: angiogenic and cell therapies.

Cooke, John P; Losordo, Douglas W.

Circ Res; 116(9): 1561-78, 2015 Apr 24.

Artículo en Inglés | MEDLINE | ID: mdl-25908729

9.

Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference.

Povsic, Thomas J; Scott, Rob; Mahaffey, Kenneth W; Blaustein, Robert; Edelberg, Jay M; Lefkowitz, Martin P; Solomon, Scott D; Fox, Jonathan C; Healy, Kevin E; Khakoo, Aarif Y; Losordo, Douglas W; Malik, Fady I; Monia, Brett P; Montgomery, Rusty L; Riesmeyer, Jeffrey; Schwartz, Gregory G; Zelenkofske, Steven L; Wu, Joseph C; Wasserman, Scott M; Roe, Matthew T.

Cardiovasc Drugs Ther; 31(4): 445-458, 2017 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-28735360

10.

Negative Regulation of miR-375 by Interleukin-10 Enhances Bone Marrow-Derived Progenitor Cell-Mediated Myocardial Repair and Function After Myocardial Infarction.

Garikipati, Venkata Naga Srikanth; Krishnamurthy, Prasanna; Verma, Suresh Kumar; Khan, Mohsin; Abramova, Tatiana; Mackie, Alexander R; Qin, Gangjian; Benedict, Cynthia; Nickoloff, Emily; Johnson, Jennifer; Gao, Ehre; Losordo, Douglas W; Houser, Steven R; Koch, Walter J; Kishore, Raj.

Stem Cells; 33(12): 3519-29, 2015 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-26235810

11.

Genetic deletion of TNFR2 augments inflammatory response and blunts satellite-cell-mediated recovery response in a hind limb ischemia model.

Sasi, Sharath P; Rahimi, Layla; Yan, Xinhua; Silver, Marcy; Qin, Gangjian; Losordo, Douglas W; Kishore, Raj; Goukassian, David A.

FASEB J; 29(4): 1208-19, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25466901

12.

Exosomes and cardiac repair after myocardial infarction.

Sahoo, Susmita; Losordo, Douglas W.

Circ Res; 114(2): 333-44, 2014 Jan 17.

Artículo en Inglés | MEDLINE | ID: mdl-24436429

13.

A critical role of Src family kinase in SDF-1/CXCR4-mediated bone-marrow progenitor cell recruitment to the ischemic heart.

Cheng, Min; Huang, Kai; Zhou, Junlan; Yan, Dewen; Tang, Yao-Liang; Zhao, Ting C; Miller, Richard J; Kishore, Raj; Losordo, Douglas W; Qin, Gangjian.

J Mol Cell Cardiol; 81: 49-53, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25655934

14.

Angels and Demons: part II.

Losordo, Douglas W; Zeiher, Andreas M.

Circ Res; 113(1): 20-1, 2013 Jun 21.

Artículo en Inglés | MEDLINE | ID: mdl-23788504

15.

Cell therapy of peripheral arterial disease: from experimental findings to clinical trials.

Raval, Zankhana; Losordo, Douglas W.

Circ Res; 112(9): 1288-302, 2013 Apr 26.

Artículo en Inglés | MEDLINE | ID: mdl-23620237

16.

The (Translational) Road Less Traveled.

Henry, Timothy D; Povsic, Thomas J; Losordo, Douglas W.

Circ Res; 122(2): 207-209, 2018 01 19.

Artículo en Inglés | MEDLINE | ID: mdl-29348249

17.

An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure.

Penn, Marc S; Mendelsohn, Farrell O; Schaer, Gary L; Sherman, Warren; Farr, Maryjane; Pastore, Joseph; Rouy, Didier; Clemens, Ruth; Aras, Rahul; Losordo, Douglas W.

Circ Res; 112(5): 816-25, 2013 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-23429605

18.

Gli3 regulation of myogenesis is necessary for ischemia-induced angiogenesis.

Renault, Marie-Ange; Vandierdonck, Soizic; Chapouly, Candice; Yu, Yang; Qin, Gangjian; Metras, Alexandre; Couffinhal, Thierry; Losordo, Douglas W; Yao, Qinyu; Reynaud, Annabel; Jaspard-Vinassa, Béatrice; Belloc, Isabelle; Desgranges, Claude; Gadeau, Alain-Pierre.

Circ Res; 113(10): 1148-58, 2013 Oct 25.

Artículo en Inglés | MEDLINE | ID: mdl-24044950

19.

Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth.

Seo, Seungwoon; Singh, Hardeep P; Lacal, Pedro M; Sasman, Amy; Fatima, Anees; Liu, Ting; Schultz, Kathryn M; Losordo, Douglas W; Lehmann, Ordan J; Kume, Tsutomu.

Proc Natl Acad Sci U S A; 109(6): 2015-20, 2012 Feb 07.

Artículo en Inglés | MEDLINE | ID: mdl-22171010

20.

Enhanced potency of cell-based therapy for ischemic tissue repair using an injectable bioactive epitope presenting nanofiber support matrix.

Tongers, Jörn; Webber, Matthew J; Vaughan, Erin E; Sleep, Eduard; Renault, Marie-Ange; Roncalli, Jerome G; Klyachko, Ekaterina; Thorne, Tina; Yu, Yang; Marquardt, Katja-Theres; Kamide, Christine E; Ito, Aiko; Misener, Sol; Millay, Meredith; Liu, Ting; Jujo, Kentaro; Qin, Gangjian; Losordo, Douglas W; Stupp, Samuel I; Kishore, Raj.

J Mol Cell Cardiol; 74: 231-9, 2014 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-25009075

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