Detalles de la búsqueda
1.
A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.
Mol Cell;
83(19): 3558-3573.e7, 2023 10 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37802028
2.
Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation.
Molecules;
27(1)2021 Dec 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-35011476
3.
Design, synthesis and anti-HBV activity evaluation of new substituted imidazo[4,5-b]pyridines.
Bioorg Chem;
98: 103580, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32005482
4.
Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues.
Molecules;
25(19)2020 Oct 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33022923
5.
Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors.
Molecules;
25(16)2020 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32824311
6.
Synthesis, Docking Study and Kinase Inhibitory Activity of a Number of New Substituted Pyrazolo[3,4-c]pyridines.
Chem Pharm Bull (Tokyo);
65(1): 66-81, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28049917
7.
The discovery of new cytotoxic pyrazolopyridine derivatives.
Bioorg Med Chem Lett;
26(21): 5229-5233, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27720292
8.
Design and synthesis of purine analogues as highly specific ligands for FcyB, a ubiquitous fungal nucleobase transporter.
Bioorg Med Chem;
24(22): 5941-5952, 2016 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27720327
9.
Synthesis of new nebularine analogues and their inhibitory activity against adenosine deaminase.
Chem Pharm Bull (Tokyo);
63(2): 134-42, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25748785
10.
One-step rapid tracking and isolation of senescent cells in cellular systems, tissues, or animal models via GLF16.
STAR Protoc;
5(1): 102929, 2024 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38460134
11.
SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors.
Pharmaceuticals (Basel);
16(1)2023 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36678624
12.
Discovery of New 1,4,6-Trisubstituted-1H-pyrazolo[3,4-b]pyridines with Anti-Tumor Efficacy in Mouse Model of Breast Cancer.
Pharmaceutics;
15(3)2023 Feb 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36986648
13.
Novel H2S-Releasing Bifunctional Antihistamine Molecules with Improved Antipruritic and Reduced Sedative Actions.
J Med Chem;
66(14): 9607-9621, 2023 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37409873
14.
Synthesis, cytotoxic activity evaluation and mechanistic investigation of novel 3,7-diarylsubstituted 6-azaindoles.
Eur J Med Chem;
261: 115804, 2023 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37729693
15.
Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors.
J Med Chem;
66(22): 15115-15140, 2023 11 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37943012
16.
Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure-Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations.
J Med Chem;
65(19): 13305-13327, 2022 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36173355
17.
Discovery of a High Affinity Adenosine A1/A3 Receptor Antagonist with a Novel 7-Amino-pyrazolo[3,4-d]pyridazine Scaffold.
ACS Med Chem Lett;
13(6): 923-934, 2022 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35707146
18.
Immunotherapy Combined with Metronomic Dosing: An Effective Approach for the Treatment of NSCLC.
Cancers (Basel);
13(8)2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33920884
19.
New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships.
Eur J Med Chem;
218: 113387, 2021 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33774342
20.
Design and Synthesis of New Substituted Pyrazolopyridines with Potent Antiproliferative Activity.
Med Chem;
16(2): 176-191, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-30799794