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1.

Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.

Duncan-Lowey, Brianna; Tal, Nitzan; Johnson, Alex G; Rawson, Shaun; Mayer, Megan L; Doron, Shany; Millman, Adi; Melamed, Sarah; Fedorenko, Taya; Kacen, Assaf; Brandis, Alexander; Mehlman, Tevie; Amitai, Gil; Sorek, Rotem; Kranzusch, Philip J.

Cell; 186(5): 987-998.e15, 2023 03 02.

Artículo en Inglés | MEDLINE | ID: mdl-36764290

2.

A microbial transporter of the dietary antioxidant ergothioneine.

Dumitrescu, Daniel G; Gordon, Elizabeth M; Kovalyova, Yekaterina; Seminara, Anna B; Duncan-Lowey, Brianna; Forster, Emily R; Zhou, Wen; Booth, Carmen J; Shen, Aimee; Kranzusch, Philip J; Hatzios, Stavroula K.

Cell; 185(24): 4526-4540.e18, 2022 11 23.

Artículo en Inglés | MEDLINE | ID: mdl-36347253

3.

CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.

Lowey, Brianna; Whiteley, Aaron T; Keszei, Alexander F A; Morehouse, Benjamin R; Mathews, Ian T; Antine, Sadie P; Cabrera, Victor J; Kashin, Dmitry; Niemann, Percy; Jain, Mohit; Schwede, Frank; Mekalanos, John J; Shao, Sichen; Lee, Amy S Y; Kranzusch, Philip J.

Cell; 182(1): 38-49.e17, 2020 07 09.

Artículo en Inglés | MEDLINE | ID: mdl-32544385

4.

A host-microbiota interactome reveals extensive transkingdom connectivity.

Sonnert, Nicole D; Rosen, Connor E; Ghazi, Andrew R; Franzosa, Eric A; Duncan-Lowey, Brianna; González-Hernández, Jaime A; Huck, John D; Yang, Yi; Dai, Yile; Rice, Tyler A; Nguyen, Mytien T; Song, Deguang; Cao, Yiyun; Martin, Anjelica L; Bielecka, Agata A; Fischer, Suzanne; Guan, Changhui; Oh, Julia; Huttenhower, Curtis; Ring, Aaron M; Palm, Noah W.

Nature; 628(8006): 171-179, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38509360

5.

Effector-mediated membrane disruption controls cell death in CBASS antiphage defense.

Duncan-Lowey, Brianna; McNamara-Bordewick, Nora K; Tal, Nitzan; Sorek, Rotem; Kranzusch, Philip J.

Mol Cell; 81(24): 5039-5051.e5, 2021 12 16.

Artículo en Inglés | MEDLINE | ID: mdl-34784509

6.

Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.

Lau, Rebecca K; Ye, Qiaozhen; Birkholz, Erica A; Berg, Kyle R; Patel, Lucas; Mathews, Ian T; Watrous, Jeramie D; Ego, Kaori; Whiteley, Aaron T; Lowey, Brianna; Mekalanos, John J; Kranzusch, Philip J; Jain, Mohit; Pogliano, Joe; Corbett, Kevin D.

Mol Cell; 77(4): 723-733.e6, 2020 02 20.

Artículo en Inglés | MEDLINE | ID: mdl-31932164

7.

STING cyclic dinucleotide sensing originated in bacteria.

Morehouse, Benjamin R; Govande, Apurva A; Millman, Adi; Keszei, Alexander F A; Lowey, Brianna; Ofir, Gal; Shao, Sichen; Sorek, Rotem; Kranzusch, Philip J.

Nature; 586(7829): 429-433, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32877915

8.

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.

Whiteley, Aaron T; Eaglesham, James B; de Oliveira Mann, Carina C; Morehouse, Benjamin R; Lowey, Brianna; Nieminen, Eric A; Danilchanka, Olga; King, David S; Lee, Amy S Y; Mekalanos, John J; Kranzusch, Philip J.

Nature; 567(7747): 194-199, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30787435

9.

Hepatitis C virus genotypes 1-3 infections regulate lipogenic signaling and suppress cholesterol biosynthesis in hepatocytes.

Hsu, Ching-Sheng; Liu, Wei-Liang; Li, Qisheng; Lowey, Brianna; Hertz, Laura; Chao, You-Chen; Liang, T Jake; Chen, Ding-Shinn; Kao, Jia-Horng.

J Formos Med Assoc; 119(9): 1382-1395, 2020 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-32284164

10.

Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition.

Li, Qisheng; Sodroski, Catherine; Lowey, Brianna; Schweitzer, Cameron J; Cha, Helen; Zhang, Fang; Liang, T Jake.

Proc Natl Acad Sci U S A; 113(27): 7620-5, 2016 07 05.

Artículo en Inglés | MEDLINE | ID: mdl-27298373

11.

CBASS phage defense and evolution of antiviral nucleotide signaling.

Duncan-Lowey, Brianna; Kranzusch, Philip J.

Curr Opin Immunol; 74: 156-163, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-35123147

12.

Bacterial gasdermins reveal an ancient mechanism of cell death.

Johnson, Alex G; Wein, Tanita; Mayer, Megan L; Duncan-Lowey, Brianna; Yirmiya, Erez; Oppenheimer-Shaanan, Yaara; Amitai, Gil; Sorek, Rotem; Kranzusch, Philip J.

Science; 375(6577): 221-225, 2022 Jan 14.

Artículo en Inglés | MEDLINE | ID: mdl-35025633

13.

Molecular basis of CD-NTase nucleotide selection in CBASS anti-phage defense.

Govande, Apurva A; Duncan-Lowey, Brianna; Eaglesham, James B; Whiteley, Aaron T; Kranzusch, Philip J.

Cell Rep; 35(9): 109206, 2021 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-34077735

14.

CD-NTases and nucleotide second messenger signaling.

Lowey, Brianna; Kranzusch, Philip J.

Curr Biol; 30(19): R1106-R1108, 2020 10 05.

Artículo en Inglés | MEDLINE | ID: mdl-33022246

15.

Hepatitis C Virus Infection Induces Hepatic Expression of NF-κB-Inducing Kinase and Lipogenesis by Downregulating miR-122.

Lowey, Brianna; Hertz, Laura; Chiu, Stephan; Valdez, Kristin; Li, Qisheng; Liang, T Jake.

mBio; 10(4)2019 07 30.

Artículo en Inglés | MEDLINE | ID: mdl-31363036

16.

MicroRNA-135a Modulates Hepatitis C Virus Genome Replication through Downregulation of Host Antiviral Factors.

Sodroski, Catherine; Lowey, Brianna; Hertz, Laura; Jake Liang, T; Li, Qisheng.

Virol Sin; 34(2): 197-210, 2019 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-30456659

17.

Hepatitis C Virus Infection of Cultured Cells and Primary Human Hepatocytes.

Lowey, Brianna; Li, Qisheng.

Curr Protoc Cell Biol; 80(1): e54, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30058773

18.

Cellular microRNA networks regulate host dependency of hepatitis C virus infection.

Li, Qisheng; Lowey, Brianna; Sodroski, Catherine; Krishnamurthy, Siddharth; Alao, Hawwa; Cha, Helen; Chiu, Stephan; El-Diwany, Ramy; Ghany, Marc G; Liang, T Jake.

Nat Commun; 8(1): 1789, 2017 11 27.

Artículo en Inglés | MEDLINE | ID: mdl-29176620

19.

Erratum for Lowey et al., "Hepatitis C Virus Infection Induces Hepatic Expression of NF-κB-Inducing Kinase and Lipogenesis by Downregulating miR-122".