Ocean cavity regime shift reversed West Antarctic grounding line retreat in the late Holocene.

Recent geologic and modeled evidence suggests that the grounding line of the Siple Coast of the West Antarctic Ice Sheet (WAIS) retreated hundreds of kilometers beyond its present position in the middle to late Holocene and readvanced within the past 1.7 ka. This grounding line reversal has been attributed to both changing rates of isostatic rebound and regional climate change. Here, we test these two hypotheses using a proxy-informed ensemble of ice sheet model simulations with varying ocean thermal forcing, global glacioisostatic adjustment (GIA) model simulations, and coupled ice sheet-GIA simulations that consider the interactions between these processes. Our results indicate that a warm to cold ocean cavity regime shift is the most likely cause of this grounding line reversal, but that GIA influences the rate of ice sheet response to oceanic changes. This implies that the grounding line here is sensitive to future changes in sub-ice shelf ocean circulation.

Deglacial grounding-line retreat in the Ross Embayment, Antarctica, controlled by ocean and atmosphere forcing.

Modern observations appear to link warming oceanic conditions with Antarctic ice sheet grounding-line retreat. Yet, interpretations of past ice sheet retreat over the last deglaciation in the Ross Embayment, Antarctica's largest catchment, differ considerably and imply either extremely high or very low sensitivity to environmental forcing. To investigate this, we perform regional ice sheet simulations using a wide range of atmosphere and ocean forcings. Constrained by marine and terrestrial geological data, these models predict earliest retreat in the central embayment and rapid terrestrial ice sheet thinning during the Early Holocene. We find that atmospheric conditions early in the deglacial period can enhance or diminish ice sheet sensitivity to rising ocean temperatures, thereby controlling the initial timing and spatial pattern of grounding-line retreat. Through the Holocene, however, grounding-line position is much more sensitive to subshelf melt rates, implicating ocean thermal forcing as the key driver of past ice sheet retreat.

ACTN3 allele frequency in humans covaries with global latitudinal gradient.

A premature stop codon in ACTN3 resulting in α-actinin-3 deficiency (the ACTN3 577XX genotype) is common in humans and reduces strength, muscle mass, and fast-twitch fiber diameter, but increases the metabolic efficiency of skeletal muscle. Linkage disequilibrium data suggest that the ACTN3 R577X allele has undergone positive selection during human evolution. The allele has been hypothesized to be adaptive in environments with scarce resources where efficient muscle metabolism would be selected. Here we test this hypothesis by using recently developed comparative methods that account for evolutionary relatedness and gene flow among populations. We find evidence that the ACTN3 577XX genotype evolved in association with the global latitudinal gradient. Our results suggest that environmental variables related to latitudinal variation, such as species richness and mean annual temperature, may have influenced the adaptive evolution of ACTN3 577XX during recent human history.