Isolation and characterization of secondary metabolites from the leaves of Sauropus spatulifolius Beille and their potential biological assays.

Eight new compounds (1-8), along with three known related compounds (9-11) were isolated from the leaves of Sauropus spatulifolius Beille. Their structures and configurations were elucidated by means of spectrometric and the modified Mosher's method. Among the new compounds, compounds 1 and 2 were identified as ethyl 3, 6-anhydro-2-deoxy-ß-D-arabino-hexofuranoside (1) and ethyl 3, 6-anhydro-2-deoxy- hexofuranoside (2). Compounds 3-5 were the 2-acetylpyrrole derivatives and identified as 2-(2-acetyl-1H-pyrrol-1-yl)-4-hydroxybutyric acid (3), methyl 4-(2-acetyl-lH-pyrrol- 1-yl) butanoate (4) and 1, 4-bis (2-acetyl-1H-pyrrol-1-yl) butane (5), respectively. Compound 6 was elucidated as 7-megastigmane-3, 8, 9-triol. Compounds 7, 8 were identified as kaempferol-3-O-2-deoxy-ß-D-glucoside (7) and kaempferol-3-O-ß-D- glucopyranosyl-(1-6)-2-deoxy-ß-D-glucoside (8). In addition, the cytotoxic activities of all the compounds were also evaluated, where compounds 3, 5, 7, 9\10 and 11 exhibited the magnificent inhibition activity on lung fibroblast differentiation induced by TGF-ß1with low toxicity against the RLE-6TN cell.

Structure, growth, and optical properties of TbAl3(BO3)4 single crystal.

TbAl(3)(BO(3))(4) single crystal was grown from a K(2)Mo(3)O(10)-B(2)O(3) system using the top-seeded high temperature solution method (TSSG), 20 mm×9 mm×7 mm in size. The grown crystal was characterized by x-ray diffraction analysis showing that the crystal has a trigonal structure and the space group is R32 with lattice parameters of a = b = 9.293(13) Å, c = 7.249(6) Å. Faraday rotations of TbAl(3)(BO(3))(4) crystal were investigated at room temperature at wavelengths of 532, 633, and 1064 nm. Finally, the Verdet constants were measured at V = -108.8, -85.7, and -20.8 rad/mT for 532, 633, and 1064 nm, respectively.