1.
Org Biomol Chem
; 4(7): 1313-27, 2006 Apr 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-16557320
RESUMEN
The enantioselective synthesis of acyclic pyrrole, indole and other N-carbazole carbinols via ligand-mediated addition of lithium carbazolates to aldehydes, together with studies into their catalytic enantioselective synthesis using substoichiometric base and ligand, are reported. The subsequent exploitation of the resulting stereocentre as a controlling element in 1,3-syn- and anti-selective reduction of beta-ketones and elaboration to homoallylic alcohols is also described.