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1.
Biomed Mater ; 19(5)2024 Aug 14.
Artículo en Inglés | MEDLINE | ID: mdl-39094619

RESUMEN

The appropriate degradation characteristics of polydioxanone (PDO) are necessary for the safety and effectiveness of stents. This study aimed to investigate the degradation of PDO weaving tracheal stents (PW stents)in vitroandin vivo. The degradation solution ofS. aureus(SAU),E. coli(ECO),P. aeruginosa(PAE), and control (N) were prepared, and the PW stents were immersed for 12 weeks. Then, the radial support force, weight retention, pH, molecular structure, thermal performance, and morphology were determined. Furthermore, the PW stents were implanted into the abdominal cavity of rabbits, and omentum was embedded. At feeding for 16 weeks, the mechanical properties, and morphology were measured. During the first 8 weeks, the radial support force in all groups was progressively decreased. At week 2, the decline rate of radial support force in the experimental groups was significantly faster compared to the N group, and the difference was narrowed thereafter. The infrared spectrum showed that during the whole degradation process, SAU, ECO and PAE solution did not lead to the formation of new functional groups in PW stents.In vitroscanning electron microscope observation showed that SAU and ECO were more likely to gather and multiply at the weaving points of the PW stents, forming colonies.In vivoexperiments showed that the degradation in the concavity of weaving points of PW stents was more rapid and severe. The radial support loss rate reached more than 70% at week 4, and the radial support force was no longer measurable after week 8. In omentum, multinuclear giant cells and foreign giant cells were found to infiltrate. PW stents have good biocompatibility. The degradation rate of PW stents in the aseptic conditionsin vivowas faster than in the bacteriological environmentin vitro.


Asunto(s)
Ensayo de Materiales , Polidioxanona , Stents , Tráquea , Animales , Polidioxanona/química , Conejos , Materiales Biocompatibles/química , Staphylococcus aureus , Escherichia coli , Pseudomonas aeruginosa , Concentración de Iones de Hidrógeno , Epiplón
2.
J Funct Biomater ; 13(3)2022 Jul 16.
Artículo en Inglés | MEDLINE | ID: mdl-35893464

RESUMEN

The repair and reconstruction of tracheal defects is a challenging clinical problem. Due to the wide choice of materials and structures, weaving technology has shown unique advantages in simulating the multilayer structure of the trachea and providing reliable performance. Currently, most woven stent-based stents focus only on the effect of materials on stent performance while ignoring the direct effect of woven process parameters on stent performance, and the advantages of weaving technology in tissue regeneration have not been fully exploited. Therefore, this review will introduce the effects of stent materials and fabric construction on the performance of tracheal stents, focusing on the effects of weaving process parameters on stent performance. We will summarize the problems faced by woven stents and possible directions of development in the hope of broadening the technical field of artificial trachea preparation.

3.
Colloids Surf B Biointerfaces ; 215: 112488, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-35390595

RESUMEN

The present paper describes a novel multi-functional Calotropis gigantea (CG) fabric with durable antibacterial property and comfortable wearability for various applications. First, antibacterial microspheres (AMs) were prepared by self-assembly of silk fibroin (SF), chitosan (CS) and nano-silver microspheres (NSMs). Oxygen low-temperature plasma (OLTP) treatment was used to improve the adhesion between AMs and CG yarn. The AMs modified CG fabric has soft hand feeling, high moisture regain (10.37 ± 1.87%), good breathability, strong wrinkle resistance, and durable antibacterial properties. The antibacterial rate of the modified CG fabric against Escherichia coli (E. Coil) and Staphylococcus aureus (S. Aureus) is as high as 99.9 ± 0.1%, and it still has an antibacterial activity after washing 20 times (90.24 ± 0.65% and 80.25 ± 1.14%, respectively). The in vivo biocompatibility test showed clear signs of angiogenesis at the implantation site in the rats. Thus, this study offers the foundation for the development of functional CG fiber-based biomedical textiles.


Asunto(s)
Calotropis , Quitosano , Fibroínas , Animales , Antibacterianos/farmacología , Escherichia coli , Fibroínas/farmacología , Microesferas , Oxígeno , Ratas , Seda , Staphylococcus aureus , Temperatura , Textiles
4.
Bioresour Technol ; 332: 125108, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-33845320

RESUMEN

Polyacrylate containing wastewater (PCW) is the typical sewage discharged by the textile industry. It has extremely poor biodegradability, and chemical methods were used conventionally as the only way for treating PCW. This study is demonstrating a novel biological method. In batch experiment monod kinetics was applied to the experimental data, which indicated that anaerobic treatment used for PCW is feasible. The pilot-scale experiment combined a Spiral Symmetry Stream Anaerobic Bioreactor (SSSAB) and an air-lift external circulation vortex enhancement nitrogen removal fluidized bed bioreactor (AFB). The COD and NH4+-N removal reached up to 95.2% and 96.6%, respectively, which were higher than the value obtained by other chemical methods. High-throughput sequencing analysis indicated that the relative abundance of Proteobacteria, Firmicutes and Bacteroidetes increased, which contribute to the degradation of PCW. Therefore, PCW can be degraded efficiently by using a SSSAB-AFB technique and thus provides an alternative to the chemical methods.


Asunto(s)
Eliminación de Residuos Líquidos , Aguas Residuales , Anaerobiosis , Reactores Biológicos , Aguas del Alcantarillado
5.
Polymers (Basel) ; 12(2)2020 Feb 12.
Artículo en Inglés | MEDLINE | ID: mdl-32059351

RESUMEN

Water transfer through porous textiles consists of two sequential processes: synchronous wicking-evaporating and evaporating alone. In this work we set out to identify the main structural parameters affecting the water transfer process of cotton fabrics. Eight woven fabrics with different floats were produced. The fabrics were evaluated on a specially designed instrument capable of measuring the water loss through a vertical wicking process. Each test took 120 min, and two phases were defined: Phase I for the first 10 min and Phase II for the last 110 min according to wicking behavior transition. Principal components and multivariate statistical methods were utilized to analyze the data collected. The results showed that Phase I dominated the whole wicking-evaporating process, and the moisture transfer speed in this phase varied with fabric structure, whereas the moisture transfer speeds in Phase II were similar and constant regardless of fabric structure. In addition, fabric with more floats has high water transfer speed in Phase I due to its loosened structure with more macropores.

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