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1.
Translational Development Strategies for TAK-063, a Phosphodiesterase 10A Inhibitor.
Int J Neuropsychopharmacol;
23(8): 524-532, 2020 11 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-32598478
2.
A human [(11)C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor.
Neuroimage;
141: 10-17, 2016 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27423256
3.
Ensuring Stakeholder Feedback in the Design and Conduct of Clinical Trials for Rare Diseases: ISCTM Position Paper of the Orphan Disease Working Group.
Innov Clin Neurosci;
21(1-3): 52-60, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38495603
4.
Intrathecal Onasemnogene Abeparvovec for Sitting, Nonambulatory Patients with Spinal Muscular Atrophy: Phase I Ascending-Dose Study (STRONG).
J Neuromuscul Dis;
10(3): 389-404, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36911944
5.
Onasemnogene abeparvovec for presymptomatic infants with two copies of SMN2 at risk for spinal muscular atrophy type 1: the Phase III SPR1NT trial.
Nat Med;
28(7): 1381-1389, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35715566
6.
Onasemnogene abeparvovec for presymptomatic infants with three copies of SMN2 at risk for spinal muscular atrophy: the Phase III SPR1NT trial.
Nat Med;
28(7): 1390-1397, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35715567
7.
Onasemnogene abeparvovec gene therapy for symptomatic infantile-onset spinal muscular atrophy in patients with two copies of SMN2 (STR1VE): an open-label, single-arm, multicentre, phase 3 trial.
Lancet Neurol;
20(4): 284-293, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33743238
8.
A randomized, placebo-controlled, phase 1 study to evaluate the effects of TAK-063 on ketamine-induced changes in fMRI BOLD signal in healthy subjects.
Psychopharmacology (Berl);
237(2): 317-328, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31773211
9.
Asenapine versus olanzapine in acute mania: a double-blind extension study.
Bipolar Disord;
11(8): 815-26, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19832806
10.
A 3-week, randomized, placebo-controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states.
Bipolar Disord;
11(7): 673-86, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19839993
11.
A phase 2, randomized, placebo-controlled study of the efficacy and safety of TAK-063 in subjects with an acute exacerbation of schizophrenia.
Schizophr Res;
204: 289-294, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30190165
12.
A Randomized Multiple Dose Pharmacokinetic Study of a Novel PDE10A Inhibitor TAK-063 in Subjects with Stable Schizophrenia and Japanese Subjects and Modeling of Exposure Relationships to Adverse Events.
Drugs R D;
17(4): 631-643, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29103081
13.
Efficacy and safety of sublingual ramelteon as an adjunctive therapy in the maintenance treatment of bipolar I disorder in adults: A phase 3, randomized controlled trial.
J Affect Disord;
221: 275-282, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28662460
14.
A phase 1 study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of TAK-063, a selective PDE10A inhibitor.
Psychopharmacology (Berl);
233(21-22): 3787-3795, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-27572830
15.
Sleep, Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group.
Neurotherapeutics;
13(2): 403-17, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27002812
16.
Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study.
J Affect Disord;
126(3): 358-65, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20537396
17.
Asenapine in the treatment of acute mania in bipolar I disorder: a randomized, double-blind, placebo-controlled trial.
J Affect Disord;
122(1-2): 27-38, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20096936
18.
Dissociation of protein kinase-mediated regulation of metabotropic glutamate receptor 7 (mGluR7) interactions with calmodulin and regulation of mGluR7 function.
Mol Pharmacol;
61(6): 1303-12, 2002 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12021391
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