Detalles de la búsqueda
1.
Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina.
Int J Mol Sci;
24(21)2023 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37958673
2.
Endocannabinoid metabolism and transport as targets to regulate intraocular pressure.
Exp Eye Res;
201: 108266, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32979397
3.
Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors.
Bioorg Med Chem;
28(1): 115195, 2020 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31761726
4.
Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment.
Bioorg Med Chem;
27(1): 55-64, 2019 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30446439
5.
Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology.
Bioorg Med Chem;
27(23): 115096, 2019 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31629610
6.
Secretion, isotopic labeling and deglycosylation of N-acylethanolamine acid amidase for biophysical studies.
Protein Expr Purif;
145: 108-117, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29253688
7.
Oximes short-acting CB1 receptor agonists.
Bioorg Med Chem;
26(18): 4963-4970, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30122284
8.
P2X7 receptor-dependent increase in endocannabinoid 2-arachidonoyl glycerol production by neuronal cells in culture: Dynamics and mechanism.
Br J Pharmacol;
2024 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38581262
9.
Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors.
ChemMedChem;
18(21): e202100406, 2023 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34486233
10.
Novel triazines as potent and selective phosphodiesterase 10A inhibitors.
Bioorg Med Chem Lett;
22(18): 5876-84, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22902656
11.
Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase.
Sci Rep;
12(1): 5328, 2022 03 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35351947
12.
Inhibition of triple negative breast cancer-associated inflammation and progression by N- acylethanolamine acid amide hydrolase (NAAA).
Sci Rep;
12(1): 22255, 2022 12 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-36564457
13.
N-Acylethanolamine acid amidase (NAAA) is dysregulated in colorectal cancer patients and its inhibition reduces experimental cancer growth.
Br J Pharmacol;
179(8): 1679-1694, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34791641
14.
New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: exploring the S2' region.
Bioorg Med Chem Lett;
21(18): 5164-70, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21835615
15.
Estrogen receptor beta agonism increases survival in experimentally induced sepsis and ameliorates the genomic sepsis signature: a pharmacogenomic study.
J Infect Dis;
201(8): 1250-7, 2010 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20205571
16.
N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition, but Not Fatty Acid Amide Hydrolase Inhibition, Prevents the Development of Experimental Autoimmune Encephalomyelitis in Mice.
Neurotherapeutics;
18(3): 1815-1833, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34235639
17.
The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity.
Neuropharmacology;
185: 108450, 2021 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33450278
18.
N-Acylethanolamine Acid Amidase Inhibition Potentiates Morphine Analgesia and Delays the Development of Tolerance.
Neurotherapeutics;
18(4): 2722-2736, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34553321
19.
Corrigendum: Metabolic Profiling of a CB2 Agonist, AM9338, Using LC-MS and Microcoil-NMR: Identification of a Novel Dihydroxy Adamantyl Metabolite.
Front Pharmacol;
12: 630274, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33967764
20.
Design and Structure-Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors.
J Med Chem;
64(9): 5956-5972, 2021 05 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33900772