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1.
Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss.
Glia;
71(4): 974-990, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36480007
2.
Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions.
Hum Mol Genet;
29(19): 3224-3248, 2020 11 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32959884
3.
A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia.
FASEB J;
34(2): 2436-2450, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31907987
4.
Post mortem examination of Parkinson's disease brains suggests decline in mitochondrial biomass, reversed by deep brain stimulation of subthalamic nucleus.
FASEB J;
33(6): 6957-6961, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30862197
5.
Sensory-specific satiation with a pinched nose and eyes closed: testing the sensory modality specificity of satiation.
Chem Senses;
39(2): 177-82, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24336692
6.
Microglia-astrocyte crosstalk in the amyloid plaque niche of an Alzheimer's disease mouse model, as revealed by spatial transcriptomics.
Cell Rep;
43(6): 114216, 2024 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38819990
7.
Differential LRRK2 signalling and gene expression in WT-LRRK2 and G2019S-LRRK2 mouse microglia treated with zymosan and MLi2.
bioRxiv;
2023 Sep 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37745519
8.
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2.
Cells;
13(1)2023 12 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38201257
9.
The influence of the R47H triggering receptor expressed on myeloid cells 2 variant on microglial exosome profiles.
Brain Commun;
3(2): fcab009, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34704019
10.
Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome.
Sci Rep;
11(1): 13316, 2021 06 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34172778
11.
Differential Stimulation of Pluripotent Stem Cell-Derived Human Microglia Leads to Exosomal Proteomic Changes Affecting Neurons.
Cells;
10(11)2021 10 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34831089
12.
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
Mol Neurodegener;
13(1): 49, 2018 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30185230
13.
Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis.
Cell Rep;
24(9): 2300-2311, 2018 08 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30157425
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