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1.
Psychiatr Psychol Law ; 28(4): 546-559, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-35558151

RESUMEN

We examined how much information British and Arab truth tellers and lie tellers volunteer in an initial free narrative. Based on cultural differences in communication styles we predicted that British interviewees would report more details and more complications than Arab interviewees (culture main effect). We further predicted that truth tellers would report more details and complications than lie tellers (veracity main effect), particularly in the British sample (Veracity × Culture interaction effect). A total of 78 British and 76 Israeli-Arab participants took part. The experiment was carried out at a British university and an Israeli university. Participants carried out a mission. Truth tellers were instructed to report the mission truthfully in a subsequent interview whereas lie tellers were asked to lie about certain aspects of the mission. The three hypotheses were supported for details, whereas for complications only the predicted veracity main effect occurred.

2.
Law Hum Behav ; 41(6): 519-529, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-28726439

RESUMEN

Research examining how truth tellers' and liars' verbal behavior is attenuated as a function of delay is largely absent from the literature, despite its important applied value. We examined this factor across 2 studies in which we examined the effects of a hypothetical delay (Experiment 1) or actual delay (Experiment 2) on liars' accounts. In Experiment 1-an insurance claim interview setting-claimants either genuinely experienced a (staged) loss of a tablet device (n = 40) or pretended to have experienced the same loss (n = 40). Truth tellers were interviewed either immediately after the loss (n = 20) or 3 weeks after the loss (n = 20), whereas liars had to either pretend the loss occurred either immediately before (n = 20) or 3 weeks before (n = 20) the interview (i.e., hypothetical delay for liars). In Experiment 2-a Human Intelligence gathering setting-sources had to either lie (n = 50) or tell the truth (n = 50) about a secret video they had seen concerning the placing of a spy device. Half of the truth tellers and liars where interviewed immediately after watching the video (n = 50), and half where interviewed 3-weeks later (n = 50; i.e., real delay for liars). Across both experiments, truth tellers interviewed after a delay reported fewer details than truth tellers interviewed immediately after the to-be-remembered event. In both studies, liars failed to simulate this pattern of forgetting and reported similar amounts of detail when interviewed without or after a delay, demonstrating a stability bias in reporting. (PsycINFO Database Record


Asunto(s)
Decepción , Conducta Verbal , Adolescente , Adulto , Femenino , Humanos , Entrevistas como Asunto , Maquiavelismo , Masculino , Persona de Mediana Edad , Adulto Joven
3.
J Neuroophthalmol ; 36(1): 58-60, 2016 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-26295608

RESUMEN

Cilioretinal artery territory infarction can occur in isolation or in association with other vascular compromise of the retinal circulation. Our patient, an 18-year-old woman with neurofibromatosis type 2, developed a cilioretinal artery territory infarction in the setting of papilledema. Our case, together with one previous report, suggests that cilioretinal artery territory infarction in the context of papilledema, although rare, is a real entity.


Asunto(s)
Arterias Ciliares/patología , Ojo/irrigación sanguínea , Infarto/etiología , Neurofibromatosis 2/complicaciones , Papiledema/etiología , Arteria Retiniana/patología , Acetazolamida/uso terapéutico , Adolescente , Aspirina/uso terapéutico , Inhibidores de Anhidrasa Carbónica , Quimioterapia Combinada , Femenino , Fibrinolíticos/uso terapéutico , Humanos , Infarto/diagnóstico , Infarto/tratamiento farmacológico , Imagen por Resonancia Magnética , Papiledema/diagnóstico , Papiledema/tratamiento farmacológico , Tomografía de Coherencia Óptica
4.
Hum Mol Genet ; 21(18): 4138-50, 2012 Sep 15.
Artículo en Inglés | MEDLINE | ID: mdl-22694956

RESUMEN

Age-related macular degeneration (AMD) is a leading cause of visual loss in Western populations. Susceptibility is influenced by age, environmental and genetic factors. Known genetic risk loci do not account for all the heritability. We therefore carried out a genome-wide association study of AMD in the UK population with 893 cases of advanced AMD and 2199 controls. This showed an association with the well-established AMD risk loci ARMS2 (age-related maculopathy susceptibility 2)-HTRA1 (HtrA serine peptidase 1) (P =2.7 × 10(-72)), CFH (complement factor H) (P =2.3 × 10(-47)), C2 (complement component 2)-CFB (complement factor B) (P =5.2 × 10(-9)), C3 (complement component 3) (P =2.2 × 10(-3)) and CFI (P =3.6 × 10(-3)) and with more recently reported risk loci at VEGFA (P =1.2 × 10(-3)) and LIPC (hepatic lipase) (P =0.04). Using a replication sample of 1411 advanced AMD cases and 1431 examined controls, we confirmed a novel association between AMD and single-nucleotide polymorphisms on chromosome 6p21.3 at TNXB (tenascin XB)-FKBPL (FK506 binding protein like) [rs12153855/rs9391734; discovery P =4.3 × 10(-7), replication P =3.0 × 10(-4), combined P =1.3 × 10(-9), odds ratio (OR) = 1.4, 95% confidence interval (CI) = 1.3-1.6] and the neighbouring gene NOTCH4 (Notch 4) (rs2071277; discovery P =3.2 × 10(-8), replication P =3.8 × 10(-5), combined P =2.0 × 10(-11), OR = 1.3, 95% CI = 1.2-1.4). These associations remained significant in conditional analyses which included the adjacent C2-CFB locus. TNXB, FKBPL and NOTCH4 are all plausible AMD susceptibility genes, but further research will be needed to identify the causal variants and determine whether any of these genes are involved in the pathogenesis of AMD.


Asunto(s)
Cromosomas Humanos Par 6 , Estudio de Asociación del Genoma Completo , Inmunofilinas/genética , Degeneración Macular/genética , Proteínas Proto-Oncogénicas/genética , Receptores Notch/genética , Tenascina/genética , Anciano , Anciano de 80 o más Años , Estudios de Casos y Controles , Femenino , Sitios Genéticos , Predisposición Genética a la Enfermedad , Haplotipos , Humanos , Modelos Lineales , Modelos Logísticos , Masculino , Oportunidad Relativa , Polimorfismo de Nucleótido Simple , Análisis de Componente Principal , Receptor Notch4 , Análisis de Secuencia de ADN , Proteínas de Unión a Tacrolimus
5.
Adv Wound Care (New Rochelle) ; 13(6): 291-307, 2024 06.
Artículo en Inglés | MEDLINE | ID: mdl-38205649

RESUMEN

Objective: While the use of negative pressure wound therapy (NPWT) with reticulated open cell foam (ROCF) is well established, the characteristics of ROCF do not allow for extended-wear use. There is the potential for dressing tissue ingrowth if left in place for greater than the recommended 2-3 days. An easy to use, novel peel and place dressing has been designed for extended wear with the wound management advantages of ROCF while alleviating the challenges of tissue ingrowth. Approach: Paraspinal, full-thickness or deep muscle excisional wounds were created in 11 and 2 swine, respectively, dressings applied with continuous negative pressure at -125 mmHg, and dressings changed weekly. Full-thickness excisional wounds were treated for 13 days and deep muscle wounds for 35 days. Wound dimensions were assessed. Granulation tissue thickness and re-epithelialization were measured via digital morphometry. Tissue quality, fibrinous material prevalence, and dressing removal peel force were analyzed. Results: The peel and place dressing substantially reduces dressing tissue ingrowth, is easy to remove with markedly low dressing peel force and promotes more granulation tissue at day 13 than ROCF with an interface layer. The extended-wear peel and place dressing, when applied to deep muscle wounds with weekly dressing changes, was applied for a total of 35 days. Successful wound closure was evident without any negative impact on wound healing. Innovation: This study assessed the wound management capabilities of an extended-wear peel and place NPWT dressing used until wound closure. Conclusion: The peel and place dressing is a suitable extended-wear NPWT dressing.


Asunto(s)
Modelos Animales de Enfermedad , Terapia de Presión Negativa para Heridas , Cicatrización de Heridas , Animales , Terapia de Presión Negativa para Heridas/métodos , Porcinos , Vendajes , Tejido de Granulación/patología , Repitelización , Femenino
6.
Eye (Lond) ; 38(1): 179-184, 2024 01.
Artículo en Inglés | MEDLINE | ID: mdl-37419960

RESUMEN

BACKGROUND/OBJECTIVES: Currently, all pregnant women with diabetes are asked to attend screening at least twice during pregnancy, even if no retinopathy is detected in early pregnancy. We hypothesise that for women with no diabetic retinopathy in early pregnancy, the frequency of retinal screening may be safely reduced. SUBJECTS/METHODS: In this retrospective cohort study, data for 4718 pregnant women attending one of three UK Diabetic Eye Screening (DES) Programmes between July 2011 and October 2019 was extracted. The women's UK DES grades at 13 weeks gestation (early pregnancy) and 28 weeks gestation (late pregnancy) were recorded. Descriptive statistics were used to report baseline data. Ordered logistic regression was used to control for covariates, such as age, ethnicity, diabetes duration, and diabetes type. RESULTS: Of the women with grades recorded for both early and late pregnancy, a total of 3085 (65.39%) women had no retinopathy in early pregnancy, and 2306 (74.7%) of these women did not develop any retinopathy by 28 weeks. The number of women without retinopathy in early pregnancy who developed referable retinopathy was 14 (0.45%), none of whom required treatment. Diabetic Retinopathy in early pregnancy remained a significant predictor of DES grade in late pregnancy when covariates of Age, Ethnicity, and Diabetes Type were controlled for (P < 0.001). CONCLUSIONS: In summary, this study has demonstrated that the burden of managing diabetes for pregnant mothers may be safely reduced by limiting the number of diabetic eye screening appointments in women who have no retinal changes in early pregnancy. Screening of women with retinopathy in early pregnancy should continue in line with current UK guidance.


Asunto(s)
Diabetes Mellitus , Retinopatía Diabética , Femenino , Humanos , Embarazo , Masculino , Retinopatía Diabética/diagnóstico , Mujeres Embarazadas , Estudios Retrospectivos , Tamizaje Masivo , Reino Unido/epidemiología
7.
Diabetologia ; 56(10): 2187-93, 2013 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-23793717

RESUMEN

AIMS/HYPOTHESIS: This study evaluated whether repeated non-attendance for diabetic eye screening is associated with the risk of sight-threatening diabetic retinopathy (STDR). METHODS: This was a cohort study of 6,556 residents with diabetes who were invited for screening between 2008 and 2011 in a population-based eye screening programme in inner London and who attended for their first-ever screen in 2008. The proportion of participants with STDR was evaluated in relation to the number of years in which screening was missed. RESULTS: The proportion of participants who did not attend screening decreased between 2009 and 2011 (annual reduction 1.6% [95% CI 0.9%, 2.3%]). The adjusted relative odds of STDR for 210 participants who did not attend two consecutive years of screening were 3.76 (95% CI 2.14, 6.61; p < 0.001), compared with participants who were screened annually. In 605 participants with mild non-proliferative retinopathy at the first screen, the adjusted relative odds of developing proliferative or moderate to severe non-proliferative retinopathy were 5.72 (95% CI 7.43, 22.83; p = 0.013) for 53 participants who missed two screens. CONCLUSIONS/INTERPRETATION: Patients who do not attend diabetic eye screening are at increased risk of developing STDR. Tracing of non-attenders with evidence of established retinopathy should be an important fail-safe procedure.


Asunto(s)
Diabetes Mellitus Tipo 1/complicaciones , Diabetes Mellitus Tipo 2/complicaciones , Retinopatía Diabética/diagnóstico , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Diabetes Mellitus Tipo 1/fisiopatología , Diabetes Mellitus Tipo 2/fisiopatología , Retinopatía Diabética/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Adulto Joven
8.
BMJ Case Rep ; 16(7)2023 Jul 06.
Artículo en Inglés | MEDLINE | ID: mdl-37419497

RESUMEN

A man in his 60s presented for his medical retina clinic appointment, reporting increasing shortness of breath, aches and pains, and increasing insulin requirements during a difficult early lockdown. Wide-field colour fundus imaging (Optos Optomap) and an optical coherence tomography scan (Heidelberg Spectralis) revealed whitened and enlarged hyper-reflective vessels. Retinal colour photography also confirmed a creamy white discolouration of the vessels, which prompted the team to order a lipid profile. The profile showed a raised cholesterol level of 17.5 mmol/L (normal: <4mmol/L) and a marked elevated triglyceride level of 38.41 mmol/L (normal: <1.7 mmol/L).The clinical picture, alongside the biochemical results, suggested a diagnosis of secondary lipaemia retinalis due to poorly controlled diabetes. With aggressive treatment, the patient's biochemistry and vessels returned to baseline.This rare condition should be taken as an indicator of a potential underlying life-threatening medical condition and the role an ophthalmologist has in initiating potential lifesaving intervention.


Asunto(s)
Diabetes Mellitus Tipo 2 , Hiperlipidemias , Enfermedades de la Retina , Masculino , Humanos , Diabetes Mellitus Tipo 2/complicaciones , Enfermedades de la Retina/diagnóstico , Hiperlipidemias/complicaciones , Retina , Fondo de Ojo , Tomografía de Coherencia Óptica/métodos
9.
Diabetes Care ; 46(5): 1091-1097, 2023 05 01.
Artículo en Inglés | MEDLINE | ID: mdl-37062044

RESUMEN

OBJECTIVE: There is limited information on the effect of ethnicity on the development of referable sight-threatening diabetic retinopathy (STDR) in people with type 1 diabetes. This study describes the risk factors for STDR in a diverse cohort of people with type 1 diabetes attending a regional diabetes eye screening service. RESEARCH DESIGN AND METHODS: Clinical and digital retinal imaging data from 1,876 people with type 1 diabetes (50% women, 72.1% Caucasian, 17.3% African Caribbean, 2.9% Asian, and 7.6% other) with no retinopathy at baseline, attending surveillance eye screening were reviewed. Referable STDR was defined as the presence of any moderate to severe nonproliferative or preproliferative diabetic retinopathy or proliferative diabetic retinopathy or maculopathy in either eye as per U.K. National Diabetic Eye Screening criteria. Median follow-up was 6 years. RESULTS: The median (interquartile range) age of the cohort was 29 (21, 41) years. Of the cohort of 1,876 people, 359 (19%) developed STDR. People who developed STDR had higher baseline HbA1c, raised systolic blood pressure (SBP), longer diabetes duration, and were more often of African Caribbean origin (24% vs. 15.6%; P < 0.05 for all). In multivariable Cox regression analyses, African Caribbean ethnicity (hazard ratio [HR] 1.39, 95% CI 1.09-1.78, P = 0.009), baseline SBP (HR 1.01, 95% CI 1.00-1.01, P = 0.033), and baseline HbA1c (HR 1.01, 95% CI 1.00-1.01, P = 0.0001) emerged as independent risk factors for STDR. CONCLUSIONS: We observed that people with type 1 diabetes of African Caribbean ethnicity are at significantly greater risk of STDR. Further research is required to understand the mechanisms that explain this novel observation.


Asunto(s)
Diabetes Mellitus Tipo 1 , Retinopatía Diabética , Humanos , Femenino , Masculino , Diabetes Mellitus Tipo 1/complicaciones , Diabetes Mellitus Tipo 1/epidemiología , Retinopatía Diabética/diagnóstico , Hemoglobina Glucada , Etnicidad , Factores de Riesgo
10.
Br J Ophthalmol ; 2023 Jun 28.
Artículo en Inglés | MEDLINE | ID: mdl-37380352

RESUMEN

PURPOSE: To determine associations between deprivation using the Index of Multiple Deprivation (IMD and individual IMD subdomains) with incident referable diabetic retinopathy/maculopathy (termed rDR). METHODS: Anonymised demographic and screening data collected by the South-East London Diabetic Eye Screening Programme were extracted from September 2013 to December 2019. Multivariable Cox proportional models were used to explore the association between the IMD, IMD subdomains and rDR. RESULTS: From 118 508 people with diabetes who attended during the study period, 88 910 (75%) were eligible. The mean (± SD) age was 59.6 (±14.7) years; 53.94% were male, 52.58% identified as white, 94.28% had type 2 diabetes and the average duration of diabetes was 5.81 (±6.9) years; rDR occurred in 7113 patients (8.00%). Known risk factors of younger age, Black ethnicity, type 2 diabetes, more severe baseline DR and diabetes duration conferred a higher risk of incident rDR. After adjusting for these known risk factors, the multivariable analysis did not show a significant association between IMD (decile 1 vs decile 10) and rDR (HR: 1.08, 95% CI: 0.87 to 1.34, p=0.511). However, high deprivation (decile 1) in three IMD subdomains was associated with rDR, namely living environment (HR: 1.64, 95% CI: 1.12 to 2.41, p=0.011), education skills (HR: 1.64, 95% CI: 1.12 to 2.41, p=0.011) and income (HR: 1.19, 95% CI: 1.02 to 1.38, p=0.024). CONCLUSION: IMD subdomains allow for the detection of associations between aspects of deprivation and rDR, which may be missed when using the aggregate IMD. The generalisation of these findings outside the UK population requires corroboration internationally.

11.
Brain Sci ; 12(9)2022 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-36138916

RESUMEN

BACKGROUND: Sketching while narrating is an effective interview technique for eliciting information and cues to deceit. The current research examined the effects of introducing a Model Sketch in investigative interviews andis pre-registered on https://osf.io/kz9mc (accessed on 18 January 2022). METHODS: Participants (N = 163) completed a mock mission and were asked to tell the truth or to lie about it in an interview. In Phase 1 of the interview, participants provided either a free recall (control condition), sketched and narrated with exposure to a Model Sketch (Model Sketch-present condition), or sketched and narrated without exposure to a Model Sketch (Model Sketch-absent condition). In Phase 2, all participants provided a free recall without sketching. RESULTS: Truth tellers reported significantly more information than lie tellers. The Model Sketch elicited more location details than a Free recall in Phase 1 and more veracity differences than the other Modality conditions in Phase 2. CONCLUSION: The Model Sketch seems to enhance the elicitation of information and to have carryover veracity effects in a follow-up free recall.

12.
Sci Rep ; 12(1): 11196, 2022 07 01.
Artículo en Inglés | MEDLINE | ID: mdl-35778615

RESUMEN

Diabetic retinopathy (DR) screening images are heterogeneous and contain undesirable non-retinal, incorrect field and ungradable samples which require curation, a laborious task to perform manually. We developed and validated single and multi-output laterality, retinal presence, retinal field and gradability classification deep learning (DL) models for automated curation. The internal dataset comprised of 7743 images from DR screening (UK) with 1479 external test images (Portugal and Paraguay). Internal vs external multi-output laterality AUROC were right (0.994 vs 0.905), left (0.994 vs 0.911) and unidentifiable (0.996 vs 0.680). Retinal presence AUROC were (1.000 vs 1.000). Retinal field AUROC were macula (0.994 vs 0.955), nasal (0.995 vs 0.962) and other retinal field (0.997 vs 0.944). Gradability AUROC were (0.985 vs 0.918). DL effectively detects laterality, retinal presence, retinal field and gradability of DR screening images with generalisation between centres and populations. DL models could be used for automated image curation within DR screening.


Asunto(s)
Aprendizaje Profundo , Diabetes Mellitus , Retinopatía Diabética , Mácula Lútea , Retinopatía Diabética/diagnóstico por imagen , Humanos , Tamizaje Masivo/métodos , Retina/diagnóstico por imagen
13.
Graefes Arch Clin Exp Ophthalmol ; 249(2): 209-14, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-20737163

RESUMEN

BACKGROUND: Macular degeneration is known to be a bilateral disease. This study set out to determine the symmetry of phenotype between eyes of patients with bilateral early AMD (or drusen) or late-stage AMD. This may be important information when considering the likelihood of anti-VEGF treatment. METHODS: This prospective, observational, cross-sectional study graded the color fundus photographs of both eyes of 1,114 Caucasian patients with either early or late-stage AMD. Patients were recruited from a tertiary referral UK population. The main outcomes were phenotype, comparison of number, type and overall area of drusen in early AMD and symmetry of late AMD. RESULTS: The overall agreement of phenotype in the entire cohort of patients was 53%, kappa statistic (κ)=0.31, (95% CI = 0.27-0.36). Within this group, a total of 271 patients were identified with bilateral soft and hard drusen (early AMD). Symmetry of phenotype within this group was high in terms of total of area of drusen (agreement = 79%, weighted κ = 0.75) and number of drusen. In those with bilateral geographic atrophy (GA), symmetry between area of GA was moderate (agreement 72%, weighted κ = 0.54), and in those with bilateral neovascular disease (choroidal neovascularization or pigment epithelial detachment), symmetry was poor (agreement 45%, weighted κ = 0.16). Out of the entire cohort, 62% (n = 688) had neovascular disease in at least one eye and 37.5% of these had bilateral disease. CONCLUSIONS: The observed symmetry of phenotype between eyes with drusen appears to reduce in GA and neovascular forms of AMD. Overall, 53% of the cohort had symmetrical disease in terms of phenotype, 23% had neovascular disease in both eyes, 9.3% had GA in both eyes, and 39% of patients had neovascular disease in one eye and non-neovascular disease in the other. This may have implications for the potential need for anti-VEGF treatment of AMD in second eye involvement.


Asunto(s)
Neovascularización Coroidal/diagnóstico , Lateralidad Funcional , Atrofia Geográfica/patología , Degeneración Macular/diagnóstico , Drusas Retinianas/patología , Anciano , Anciano de 80 o más Años , Neovascularización Coroidal/clasificación , Estudios Transversales , Femenino , Humanos , Degeneración Macular/clasificación , Masculino , Persona de Mediana Edad , Fenotipo , Estudios Prospectivos
14.
Law Hum Behav ; 35(1): 40-8, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21061052

RESUMEN

We tested the accuracy of thermal imaging as a lie detection tool in airport screening. Fifty-one passengers in an international airport departure hall told the truth or lied about their forthcoming trip in an interview. Their skin temperature was recorded via a thermal imaging camera. Liars' skin temperature rose significantly during the interview, whereas truth tellers' skin temperature remained constant. On the basis of these different patterns, 64% of truth tellers and 69% of liars were classified correctly. The interviewers made veracity judgements independently from the thermal recordings. The interviewers outperformed the thermal recordings and classified 72% of truth tellers and 77% of liars correctly. Accuracy rates based on the combination of thermal imaging scores and interviewers' judgements were the same as accuracy rates based on interviewers' judgements alone. Implications of the findings for the suitability of thermal imaging as a lie detection tool in airports are discussed.


Asunto(s)
Aviación , Detección de Mentiras , Tamizaje Masivo/métodos , Termografía/métodos , Adolescente , Adulto , Femenino , Humanos , Entrevistas como Asunto , Masculino , Persona de Mediana Edad , Administración de la Seguridad , Temperatura Cutánea , Reino Unido , Adulto Joven
15.
Br J Ophthalmol ; 105(5): 723-728, 2021 05.
Artículo en Inglés | MEDLINE | ID: mdl-32606081

RESUMEN

BACKGROUND/AIMS: Human grading of digital images from diabetic retinopathy (DR) screening programmes represents a significant challenge, due to the increasing prevalence of diabetes. We evaluate the performance of an automated artificial intelligence (AI) algorithm to triage retinal images from the English Diabetic Eye Screening Programme (DESP) into test-positive/technical failure versus test-negative, using human grading following a standard national protocol as the reference standard. METHODS: Retinal images from 30 405 consecutive screening episodes from three English DESPs were manually graded following a standard national protocol and by an automated process with machine learning enabled software, EyeArt v2.1. Screening performance (sensitivity, specificity) and diagnostic accuracy (95% CIs) were determined using human grades as the reference standard. RESULTS: Sensitivity (95% CIs) of EyeArt was 95.7% (94.8% to 96.5%) for referable retinopathy (human graded ungradable, referable maculopathy, moderate-to-severe non-proliferative or proliferative). This comprises sensitivities of 98.3% (97.3% to 98.9%) for mild-to-moderate non-proliferative retinopathy with referable maculopathy, 100% (98.7%,100%) for moderate-to-severe non-proliferative retinopathy and 100% (97.9%,100%) for proliferative disease. EyeArt agreed with the human grade of no retinopathy (specificity) in 68% (67% to 69%), with a specificity of 54.0% (53.4% to 54.5%) when combined with non-referable retinopathy. CONCLUSION: The algorithm demonstrated safe levels of sensitivity for high-risk retinopathy in a real-world screening service, with specificity that could halve the workload for human graders. AI machine learning and deep learning algorithms such as this can provide clinically equivalent, rapid detection of retinopathy, particularly in settings where a trained workforce is unavailable or where large-scale and rapid results are needed.


Asunto(s)
Algoritmos , Inteligencia Artificial , Retinopatía Diabética/diagnóstico , Procesamiento de Imagen Asistido por Computador/métodos , Tamizaje Masivo/métodos , Retina/patología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Reproducibilidad de los Resultados , Estudios Retrospectivos , Adulto Joven
16.
Acta Psychol (Amst) ; 209: 103130, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32683098

RESUMEN

Typically, truth-tellers report more detailed statements when interviewed immediately, compared to after delays (displaying forgetting), whereas liars report statements containing similar amounts of detail when interviewed immediately or after a delay (displaying a metacognitive error). Accordingly, the diagnostic utility of the 'richness-of-detail' cue is reduced after delays. We investigated if initial interviewing can facilitate lie-detection using the richness-of-detail cue in sub-optimal memorial conditions, that is, when (i) interviewing occurred after a three-week delay and (ii) truth-teller's attention during encoding was manipulated. Participants (n = 152) witnessed an interaction, that was meaningful to (and intentionally encoded by) liars (n = 50) and half of truth-tellers (n = 51), but meaningless (and incidentally encoded by) the remaining truth-tellers (n = 51). Participants were interviewed after three weeks. Half of the intentional liars and half of the intentional and incidental truth-tellers were also interviewed immediately (initial interview-present condition), whereas the remaining participants received no immediate interview (initial interview-absent condition). Results showed intentional and incidental truth-tellers reported after three weeks more detail in the initial interview-present (versus absent) condition, whereas intentional liars' statements were unaffected by initial interviewing condition. After three weeks, more intentional liars and intentional truth-tellers were correctly distinguished in the initial interview-present (versus absent) condition.


Asunto(s)
Decepción , Recuerdo Mental , Metacognición , Humanos
17.
Acta Psychol (Amst) ; 204: 103020, 2020 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-32014621

RESUMEN

The application of alibi witness scenarios to deception detection has been overlooked. Experiment 1 was a study of the verifiability approach in which truth-telling pairs completed a mission together, whereas in lying pairs one individual completed this mission alone and the other individual committed a mock theft. All pairs were instructed to convince the interviewer that they completed the mission together by writing individual statements on their own followed by a collective statement together as a pair. In the individual statements, truth-telling pairs provided more checkable details that demonstrated they completed the mission together than lying pairs, whereas lying pairs provided more uncheckable details than truth-telling pairs. The collective statements made truth-telling pairs provide significantly more checkable details that demonstrated they were together in comparison to the individual statements, whereas no effect was obtained for lying pairs. Receiver Operating Characteristic curves revealed high accuracy rates for discriminating between truths and lies using the verifiability approach across all statement types. Experiment 2 was a lie detection study whereby observers' abilities to discriminate between truths and lies using the verifiability approach were examined. This revealed that applying the verifiability approach to collective statements improved observers' ability to accurately detect deceit. We suggest that the verifiability approach could be used as a lie detection technique and that law enforcement policies should consider implementing collective interviewing.


Asunto(s)
Decepción , Aprendizaje Discriminativo/fisiología , Detección de Mentiras/psicología , Adolescente , Adulto , Humanos , Masculino , Adulto Joven
18.
Law Hum Behav ; 33(2): 159-66, 2009 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-18523881

RESUMEN

We hypothesised that the responses of pairs of liars would correspond less with each other than would responses of pairs of truth tellers, but only when the responses are given to unanticipated questions. Liars and truth tellers were interviewed individually about having had lunch together in a restaurant. The interviewer asked typical opening questions which we expected the liars to anticipate, followed by questions about spatial and/or temporal information which we expected suspects not to anticipate, and also a request to draw the layout of the restaurant. The results supported the hypothesis, and based on correspondence in responses to the unanticipated questions, up to 80% of liars and truth tellers could be correctly classified, particularly when assessing drawings.


Asunto(s)
Entrevistas como Asunto , Detección de Mentiras , Derecho Penal , Femenino , Humanos , Masculino
19.
Acta Psychol (Amst) ; 200: 102935, 2019 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-31715443

RESUMEN

Truth tellers provide less detail in delayed than in immediate interviews (likely due to forgetting), whereas liars provide similar amounts of detail in immediate and delayed interviews (displaying a metacognitive stability bias effect). We examined whether liar's flawed metacognition after delays could be exploited by encouraging interviewees to provide more detail via a Model Statement. Truthful and deceptive participants were interviewed immediately (n = 78) or after a three-week delay (n = 78). Half the participants in each condition listened to a Model Statement before questioning. In the Immediate condition, truth tellers provided more details than liars. This pattern was unaffected by the Model Statement. In the Delayed condition, truth tellers and liars provided a similar amount of detail in the Model Statement-absent condition, whereas in the Model Statement-present condition, liars provided more details than truth tellers.


Asunto(s)
Estimulación Acústica/psicología , Percepción Auditiva/fisiología , Decepción , Revelación , Relaciones Interpersonales , Metacognición/fisiología , Estimulación Acústica/métodos , Adolescente , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
20.
Eur. j. psychol. appl. legal context (Internet) ; 16(1): 1-15, Jan. 2024. tab, graf
Artículo en Inglés | IBECS (España) | ID: ibc-230851

RESUMEN

Background/Aim: has shown that sketching while narrating facilitates the elicitation of information and verbal veracity cues in single interviews. We examined if these effects are retained when suspects are shown their sketch after one week in a repeated interview. Method: Participants (N = 173) completed a mock mission and then told the truth or lied about it in an immediate interview (interview 1). Participants either verbally reported the mission (Free recall condition) or sketched it while describing what they were sketching (sketch condition). After one week, all participants were asked for a free recall without sketching (interview 2). Half of the participants in the Sketch condition had access to their sketch while they verbally reported the event whereas the remaining half did not access the sketch. Results: Truth tellers provided more information than lie tellers in both interviews, and sketching elicited more information than a free recall but only in Interview 1. Participants who had access to their sketch in interview 2 repeated more information than those who did not have access, but accessing the sketch did not have an effect on veracity cues. Conclusions: Thus, sketching enhanced the elicitation of information in Interview 1 and access to the sketch in interview 2 seemed helpful for recalling previously reported information. (AU)


Antecedentes/objetivo: La investigación ha revelado que el uso de esquemas mientras se lleva a cabo una narración facilita la obtención de información y de indicios verbales de veracidad en una entrevista. Analizamos si estos efectos se mantienen cuando se somete a los sospechosos a su esquema de los hechos en entrevistas repetidas (una semana después). Método: Los participantes (N = 173) completaron una misión simulada y luego contaban la verdad o mentían sobre la misma en una entrevista realizada de modo inmediato (entrevista 1). Los participantes o bien referían verbalmente la misión (condición de recuerdo libre) o la esquematizaban (condición de esquematización). Después de una semana se pidió a todos los participantes un recuerdo libre sin esquematizar (entrevista 2). La mitad de los participantes de la condición de esquematización podían acceder a su esquema mientras referían verbalmente el suceso y la otra mitad no tenía acceso al esquema. Resultados: Los que contaban la verdad daban más información que los que mentían en ambas entrevistas y el esquema facilitaba más información que el recuerdo libre aunque tan solo en la entrevista 1. Aquellos participantes que tenían acceso a su esquema en la entrevista 2 repetían más información que quienes no tenían acceso, aunque el acceso no tenía efecto alguno en indicios de veracidad. Conclusiones: En conclusión, los esquemas incrementaron la obtención de información en la entrevista 1 y el acceso al esquema en la entrevista 2 resultó útil para recordar la información relatada previamente. (AU)


Asunto(s)
Humanos , Detección de Mentiras/psicología , Entrevista Psicológica , Entrevistas como Asunto/métodos
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