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1.

The Effect of Spironolactone in Patients With Obesity at Risk for Heart Failure: Proteomic Insights from the HOMAGE Trial.

Verdonschot, Job A J; Ferreira, JoÃo Pedro; Pizard, Anne; Pellicori, Pierpaolo; Brunner La Rocca, Hans-Peter; Clark, Andrew L; Cosmi, Franco; Cuthbert, Joe; Girerd, Nicolas; Waring, Olivia J; Henkens, Michiel H T M; Mariottoni, Beatrice; Petutschnigg, Johannes; Rossignol, Patrick; Hazebroek, Mark R; Cleland, John G F; Zannad, Faiez; Heymans, Stephane R B.

J Card Fail; 28(5): 778-786, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-34933097

2.

The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart 'OMics' in AGEing (HOMAGE) randomized clinical trial.

Cleland, John G F; Ferreira, João Pedro; Mariottoni, Beatrice; Pellicori, Pierpaolo; Cuthbert, Joe; Verdonschot, Job A J; Petutschnigg, Johannes; Ahmed, Fozia Z; Cosmi, Franco; Brunner La Rocca, Hans-Peter; Mamas, Mamas A; Clark, Andrew L; Edelmann, Frank; Pieske, Burkert; Khan, Javed; McDonald, Ken; Rouet, Philippe; Staessen, Jan A; Mujaj, Blerim; González, Arantxa; Diez, Javier; Hazebroek, Mark; Heymans, Stephane; Latini, Roberto; Grojean, Stéphanie; Pizard, Anne; Girerd, Nicolas; Rossignol, Patrick; Collier, Tim J; Zannad, Faiez.

Eur Heart J; 42(6): 684-696, 2021 02 11.

Artículo en Inglés | MEDLINE | ID: mdl-33215209

3.

Proteomic mechanistic profile of patients with diabetes at risk of developing heart failure: insights from the HOMAGE trial.

Verdonschot, Job A J; Ferreira, João Pedro; Pellicori, Pierpaolo; Brunner-La Rocca, Hans-Peter; Clark, Andrew L; Cosmi, Franco; Cuthbert, Joe; Girerd, Nicolas; Mariottoni, Beatrice; Petutschnigg, Johannes; Rossignol, Patrick; Cleland, John G F; Zannad, Faiez; Heymans, Stephane R B.

Cardiovasc Diabetol; 20(1): 163, 2021 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-34372849

4.

Declining Risk of Sudden Death in Heart Failure.

Cosmi, Deborah; Mariottoni, Beatrice; Cosmi, Franco.

N Engl J Med; 377(18): 1793-4, 2017 11 02.

Artículo en Inglés | MEDLINE | ID: mdl-29094860

5.

Trials of Patent Foramen Ovale Closure.

Cosmi, Deborah; Mariottoni, Beatrice; Cosmi, Franco.

N Engl J Med; 377(26): 2598-2599, 2017 12 28.

Artículo en Inglés | MEDLINE | ID: mdl-29281581

6.

[Shared decision-making in metaclinical medicine: from informed consent to shared probability]. / Il processo decisionale condiviso nella medicina metaclinica: dal consenso informato alla probabilità condivisa.

Cosmi, Franco; Tarquini, Barbara; Mariottoni, Beatrice; Cosmi, Deborah.

G Ital Cardiol (Rome); 25(4): 221-228, 2024 Apr.

Artículo en Italiano | MEDLINE | ID: mdl-38526358

7.

Phenotyping patients with ischaemic heart disease at risk of developing heart failure: an analysis of the HOMAGE trial.

Santos-Ferreira, Diogo; Diaz, Sílvia O; Ferreira, João Pedro; Girerd, Nicolas; Pellicori, Pierpaolo; Mariottoni, Beatrice; Cosmi, Franco; Hazebroek, Mark; Verdonschot, Job A J; Cuthbert, Joe; Petutschnigg, Johannes; Heymans, Stephane; Staessen, Jan A; Pieske, Burkert; Edelmann, Frank; Clark, Andrew L; Rossignol, Patrick; Fontes-Carvalho, Ricardo; Cleland, John G F; Zannad, Faiez.

ESC Heart Fail; 11(1): 209-218, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-37939716

8.

Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial.

Yu, Yu-Ling; Siwy, Justyna; An, De-Wei; González, Arantxa; Hansen, Tine; Latosinska, Agnieszka; Pellicori, Pierpaolo; Ravassa, Susana; Mariottoni, Beatrice; Verdonschot, Job Aj; Ahmed, Fozia; Petutschnigg, Johannes; Rossignol, Patrick; Heymans, Stephane; Cuthbert, Joe J; Girerd, Nicolas; Clark, Andrew L; Verhamme, Peter; Nawrot, Tim S; Janssens, Stefan; Cleland, John G; Zannad, Faiez; Diez, Javier; Mischak, Harald; Ferreira, João Pedro; Staessen, Jan A.

Heart; 2024 May 09.

Artículo en Inglés | MEDLINE | ID: mdl-38729636

9.

Spironolactone effect on cardiac structure and function of patients with heart failure and preserved ejection fraction: a pooled analysis of three randomized trials.

Ferreira, João Pedro; Cleland, John G; Girerd, Nicolas; Bozec, Erwan; Rossignol, Patrick; Pellicori, Pierpaolo; Cosmi, Franco; Mariottoni, Beatrice; Solomon, Scott D; Pitt, Bertram; Pfeffer, Marc A; Shah, Amil M; Petutschnigg, Johannes; Pieske, Burkert; Edelmann, Frank; Zannad, Faiez.

Eur J Heart Fail; 25(1): 108-113, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36303266

10.

Spironolactone effect on circulating procollagen type I carboxy-terminal propeptide: Pooled analysis of three randomized trials.

Ferreira, João Pedro; Cleland, John G; Girerd, Nicolas; Rossignol, Patrick; Pellicori, Pierpaolo; Cosmi, Franco; Mariottoni, Beatrice; González, Arantxa; Diez, Javier; Solomon, Scott D; Claggett, Brian; Pfeffer, Marc A; Pitt, Bertram; Petutschnigg, Johannes; Pieske, Burkert; Edelmann, Frank; Zannad, Faiez.

Int J Cardiol; 377: 86-88, 2023 04 15.

Artículo en Inglés | MEDLINE | ID: mdl-36738846

11.

Protein Biomarkers of New-Onset Heart Failure: Insights From the Heart Omics and Ageing Cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study.

Girerd, Nicolas; Levy, Daniel; Duarte, Kevin; Ferreira, Joao Pedro; Ballantyne, Christie; Collier, Timothy; Pizard, Anne; Björkman, Jens; Butler, Javed; Clark, Andrew; Cleland, John G; Delles, Christian; Diez, Javier; González, Arantxa; Hazebroek, Mark; Ho, Jennifer; Huby, Anne-Cécile; Hwang, Shih-Jen; Latini, Roberto; Mariottoni, Beatrice; Mebazaa, Alexandre; Pellicori, Pierpaolo; Sattar, Naveed; Sever, Peter; Staessen, Jan A; Verdonschot, Job; Heymans, Stephane; Rossignol, Patrick; Zannad, Faiez.

Circ Heart Fail; 16(5): e009694, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-37192292

12.

[Process to insulin for type 2 diabetes mellitus therapy]. / Processo all'insulina nella terapia del diabete mellito di tipo 2.

Cosmi, Franco; D'Orazio, Simona; Mariottoni, Beatrice; Tarquini, Barbara; Cosmi, Deborah.

G Ital Cardiol (Rome); 23(1): 52-62, 2022 Jan.

Artículo en Italiano | MEDLINE | ID: mdl-34985463

13.

The association between markers of type I collagen synthesis and echocardiographic response to spironolactone in patients at risk of heart failure: findings from the HOMAGE trial.

Kobayashi, Masatake; Girerd, Nicolas; Ferreira, João Pedro; Kevin, Duarte; Huttin, Olivier; González, Arantxa; Bozec, Erwan; Clark, Andrew L; Cosmi, Franco; Cuthbert, Joe; Diez, Javier; Edelmann, Frank; Hazebroek, Mark; Heymans, Stephane; Mariottoni, Beatrice; Pellicori, Pierpaolo; Petutschnigg, Johannes; Pieske, Burkert; Staessen, Jan A; Verdonschot, Job A J; Rossignol, Patrick; Cleland, John G F; Zannad, Faiez.

Eur J Heart Fail; 24(9): 1559-1568, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-35703355

14.

Influence of ejection fraction on biomarker expression and response to spironolactone in people at risk of heart failure: findings from the HOMAGE trial.

Ferreira, João Pedro; Verdonschot, Job A J; Girerd, Nicolas; Bozec, Erwan; Pellicori, Pierpaolo; Collier, Timothy; Mariottoni, Beatrice; Cosmi, Franco; Hazebroek, Mark; Cuthbert, Joe; Petutschnigg, Johannes; Heymans, Stephane; Staessen, Jan A; Pieske, Burkert; Edelman, Frank; Clark, Andrew L; Díez, Javier; González, Arantxa; Rossignol, Patrick; Cleland, John G; Zannad, Faiez.

Eur J Heart Fail; 24(5): 771-778, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35199421

15.

Spironolactone effect on the blood pressure of patients at risk of developing heart failure: an analysis from the HOMAGE trial.

Ferreira, João Pedro; Collier, Timothy; Clark, Andrew L; Mamas, Mamas A; Rocca, Hans-Peter Brunner-La; Heymans, Stephane; González, Arantxa; Ahmed, Fozia Z; Petutschnigg, Johannes; Mujaj, Blerim; Cuthbert, Joe; Rouet, Philippe; Pellicori, Pierpaolo; Mariottoni, Beatrice; Cosmi, Franco; Edelmann, Frank; Thijs, Lutgarde; Staessen, Jan A; Hazebroek, Mark; Verdonschot, Job; Rossignol, Patrick; Girerd, Nicolas; Cleland, John G; Zannad, Faiez.

Eur Heart J Cardiovasc Pharmacother; 8(2): 149-156, 2022 02 16.

Artículo en Inglés | MEDLINE | ID: mdl-33822033

16.

Biomarker-based assessment of collagen cross-linking identifies patients at risk of heart failure more likely to benefit from spironolactone effects on left atrial remodelling. Insights from the HOMAGE clinical trial.

Ravassa, Susana; López, Begoña; Ferreira, João Pedro; Girerd, Nicolas; Bozec, Erwan; Pellicori, Pierpaolo; Mariottoni, Beatrice; Cosmi, Franco; Hazebroek, Mark; Verdonschot, Job A J; Cuthbert, Joe; Petutschnigg, Johannes; Moreno, María U; Heymans, Stephane; Staessen, Jan A; Pieske, Burkert; Edelmann, Frank; Clark, Andrew L; Cleland, John G F; Zannad, Faiez; Díez, Javier; González, Arantxa.

Eur J Heart Fail; 24(2): 321-331, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34841615

17.

Dyskalemia in people at increased risk for heart failure: findings from the heart 'OMics' in AGEing (HOMAGE) trial.

Monzo, Luca; Ferreira, João Pedro; Cleland, John G F; Pellicori, Pierpaolo; Mariottoni, Beatrice; Verdonschot, Job A J; Hazebroek, Mark R; Collier, Tim J; Cuthbert, Joe J; Pieske, Burkert; Edelmann, Frank; Petutschnigg, Johannes; Khan, Javed; Ahmed, Fozia Z; Girerd, Nicolas; Bozec, Erwan; Díez, Javier; González, Arantxa; Clark, Andrew L; Cosmi, Franco; Staessen, Jan A; Heymans, Stephane; Rossignol, Patrick; Zannad, Faiez.

ESC Heart Fail; 9(6): 4352-4357, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36065795

18.

Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF.

Ferreira, João Pedro; Verdonschot, Job; Wang, Ping; Pizard, Anne; Collier, Timothy; Ahmed, Fozia Z; Brunner-La-Rocca, Hans-Peter; Clark, Andrew L; Cosmi, Franco; Cuthbert, Joe; Díez, Javier; Edelmann, Frank; Girerd, Nicolas; González, Arantxa; Grojean, Stéphanie; Hazebroek, Mark; Khan, Javed; Latini, Roberto; Mamas, Mamas A; Mariottoni, Beatrice; Mujaj, Blerim; Pellicori, Pierpaolo; Petutschnigg, Johannes; Pieske, Burkert; Rossignol, Patrick; Rouet, Philippe; Staessen, Jan A; Cleland, John G F; Heymans, Stephane; Zannad, Faiez.

JACC Heart Fail; 9(4): 268-277, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33549556

19.

[The patient in clinical research: disposable guinea pig or involved actor?] / Il paziente nella ricerca clinica: cavia a disposizione o attore interessato?

Cosmi, Franco; Mariottoni, Beatrice; Tarquini, Barbara; D'Orazio, Simona; Bennati, Moira; Morganti, Monia; Cosmi, Deborah.

G Ital Cardiol (Rome); 21(4): 309-314, 2020 Apr.

Artículo en Italiano | MEDLINE | ID: mdl-32202565

20.

Effects of spironolactone on serum markers of fibrosis in people at high risk of developing heart failure: rationale, design and baseline characteristics of a proof-of-concept, randomised, precision-medicine, prevention trial. The Heart OMics in AGing (HOMAGE) trial.

Pellicori, Pierpaolo; Ferreira, João Pedro; Mariottoni, Beatrice; Brunner-La Rocca, Hans-Peter; Ahmed, Fozia Z; Verdonschot, Job; Collier, Tim; Cuthbert, Joe J; Petutschnigg, Johannes; Mujaj, Blerim; Girerd, Nicolas; González, Arantxa; Clark, Andrew L; Cosmi, Franco; Staessen, Jan A; Heymans, Stephane; Latini, Roberto; Rossignol, Patrick; Zannad, Faiez; Cleland, John G F.

Eur J Heart Fail; 22(9): 1711-1723, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-31950604

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