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1.
Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid.
PLoS Pathog;
15(5): e1007760, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31071193
2.
Tryptophan Trimers and Tetramers Inhibit Dengue and Zika Virus Replication by Interfering with Viral Attachment Processes.
Antimicrob Agents Chemother;
64(3)2020 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31932383
3.
Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase.
Bioorg Med Chem;
28(1): 115188, 2020 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31757682
4.
Optimization of a Class of Tryptophan Dendrimers That Inhibit HIV Replication Leads to a Selective, Specific, and Low-Nanomolar Inhibitor of Clinical Isolates of Enterovirus A71.
Antimicrob Agents Chemother;
60(8): 5064-7, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27246775
5.
C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
J Med Chem;
66(15): 10432-10457, 2023 08 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37471688
6.
Organotropic dendrons with high potency as HIV-1, HIV-2 and EV-A71 cell entry inhibitors.
Eur J Med Chem;
237: 114414, 2022 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35512567
7.
Synthesis and evaluation of 3-alkynyl-5-aryl-7-aza-indoles as broad-spectrum antiviral agents.
Front Chem;
10: 1058229, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36385995
8.
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies.
Antiviral Res;
204: 105367, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35738348
9.
A patent review of adaptor associated kinase 1 (AAK1) inhibitors (2013-present).
Expert Opin Ther Pat;
31(10): 911-936, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-33971786
10.
Discovery of 3-phenyl- and 3-N-piperidinyl-isothiazolo[4,3-b]pyridines as highly potent inhibitors of cyclin G-associated kinase.
Eur J Med Chem;
213: 113158, 2021 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33497888
11.
Double Arylation of the Indole Side Chain of Tri- and Tetrapodal Tryptophan Derivatives Renders Highly Potent HIV-1 and EV-A71 Entry Inhibitors.
J Med Chem;
64(14): 10027-10046, 2021 07 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34229438
12.
Scaffold Simplification Strategy Leads to a Novel Generation of Dual Human Immunodeficiency Virus and Enterovirus-A71 Entry Inhibitors.
J Med Chem;
63(1): 349-368, 2020 01 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31809045
13.
Modifications in the branched arms of a class of dual inhibitors of HIV and EV71 replication expand their antiviral spectrum.
Antiviral Res;
168: 210-214, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31228490
14.
Galloyl Carbohydrates with Antiangiogenic Activity Mediated by Capillary Morphogenesis Gene 2 (CMG2) Protein Binding.
J Med Chem;
62(8): 3958-3970, 2019 04 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-30964669
15.
Structure-activity relationship studies on a Trp dendrimer with dual activities against HIV and enterovirus A71. Modifications on the amino acid.
Antiviral Res;
139: 32-40, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-28017762
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