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1.

Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis.

Leit, Silvana; Greenwood, Jeremy R; Mondal, Sayan; Carriero, Samantha; Dahlgren, Markus; Harriman, Geraldine C; Kennedy-Smith, Joshua J; Kapeller, Rosana; Lawson, Jon P; Romero, Donna L; Toms, Angela V; Shelley, Mee; Wester, Ronald T; Westlin, William; McElwee, Joshua J; Miao, Wenyan; Edmondson, Scott D; Masse, Craig E.

Bioorg Med Chem Lett; 73: 128891, 2022 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-35842205

2.

Preclinical evaluation of tyrosine kinase 2 inhibitors for human beta-cell protection in type 1 diabetes.

Coomans de Brachène, Alexandra; Castela, Angela; Op de Beeck, Anne; Mirmira, Raghavendra G; Marselli, Lorella; Marchetti, Piero; Masse, Craig; Miao, Wenyan; Leit, Silvana; Evans-Molina, Carmella; Eizirik, Decio L.

Diabetes Obes Metab; 22(10): 1827-1836, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32476252

3.

Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.

Akahane, Koshi; Li, Zhaodong; Etchin, Julia; Berezovskaya, Alla; Gjini, Evisa; Masse, Craig E; Miao, Wenyan; Rocnik, Jennifer; Kapeller, Rosana; Greenwood, Jeremy R; Tiv, Hong; Sanda, Takaomi; Weinstock, David M; Look, A Thomas.

Br J Haematol; 177(2): 271-282, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-28295194

4.

Accurate and reliable prediction of relative ligand binding potency in prospective drug discovery by way of a modern free-energy calculation protocol and force field.

Wang, Lingle; Wu, Yujie; Deng, Yuqing; Kim, Byungchan; Pierce, Levi; Krilov, Goran; Lupyan, Dmitry; Robinson, Shaughnessy; Dahlgren, Markus K; Greenwood, Jeremy; Romero, Donna L; Masse, Craig; Knight, Jennifer L; Steinbrecher, Thomas; Beuming, Thijs; Damm, Wolfgang; Harder, Ed; Sherman, Woody; Brewer, Mark; Wester, Ron; Murcko, Mark; Frye, Leah; Farid, Ramy; Lin, Teng; Mobley, David L; Jorgensen, William L; Berne, Bruce J; Friesner, Richard A; Abel, Robert.

J Am Chem Soc; 137(7): 2695-703, 2015 Feb 25.

Artículo en Inglés | MEDLINE | ID: mdl-25625324

5.

Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279.

Leit, Silvana; Greenwood, Jeremy; Carriero, Samantha; Mondal, Sayan; Abel, Robert; Ashwell, Mark; Blanchette, Heather; Boyles, Nicholas A; Cartwright, Mark; Collis, Alan; Feng, Shulu; Ghanakota, Phani; Harriman, Geraldine C; Hosagrahara, Vinayak; Kaila, Neelu; Kapeller, Rosanna; Rafi, Salma B; Romero, Donna L; Tarantino, Paul M; Timaniya, Jignesh; Toms, Angela V; Wester, Ronald T; Westlin, William; Srivastava, Bhaskar; Miao, Wenyan; Tummino, Peter; McElwee, Joshua J; Edmondson, Scott D; Masse, Craig E.

J Med Chem; 66(15): 10473-10496, 2023 08 10.

Artículo en Inglés | MEDLINE | ID: mdl-37427891

6.

TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis.

Gracey, Eric; Hromadová, Dominika; Lim, Melissa; Qaiyum, Zoya; Zeng, Michael; Yao, Yuchen; Srinath, Archita; Baglaenko, Yuriy; Yeremenko, Natalia; Westlin, William; Masse, Craig; Müller, Mathias; Strobl, Birgit; Miao, Wenyan; Inman, Robert D.

J Clin Invest; 130(4): 1863-1878, 2020 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-32149730

7.

Accelerating drug discovery through tight integration of expert molecular design and predictive scoring.

Abel, Robert; Mondal, Sayan; Masse, Craig; Greenwood, Jeremy; Harriman, Geraldine; Ashwell, Mark A; Bhat, Sathesh; Wester, Ronald; Frye, Leah; Kapeller, Rosana; Friesner, Richard A.

Curr Opin Struct Biol; 43: 38-44, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-27816785

8.

Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.

DiMauro, Erin F; Newcomb, John; Nunes, Joseph J; Bemis, Jean E; Boucher, Christina; Buchanan, John L; Buckner, William H; Cee, Victor J; Chai, Lilly; Deak, Holly L; Epstein, Linda F; Faust, Ted; Gallant, Paul; Geuns-Meyer, Stephanie D; Gore, Anu; Gu, Yan; Henkle, Brad; Hodous, Brian L; Hsieh, Faye; Huang, Xin; Kim, Joseph L; Lee, Josie H; Martin, Matthew W; Masse, Craig E; McGowan, David C; Metz, Daniela; Mohn, Deanna; Morgenstern, Kurt A; Oliveira-dos-Santos, Antonio; Patel, Vinod F; Powers, David; Rose, Paul E; Schneider, Stephen; Tomlinson, Susan A; Tudor, Yan-Yan; Turci, Susan M; Welcher, Andrew A; White, Ryan D; Zhao, Huilin; Zhu, Li; Zhu, Xiaotian.

J Med Chem; 49(19): 5671-86, 2006 Sep 21.

Artículo en Inglés | MEDLINE | ID: mdl-16970394

9.

Cycloaddition reactions of imines with 3-thiosuccinic anhydrides: synthesis of the tricyclic core of martinellic acid.

Ng, Pui Yee; Masse, Craig E; Shaw, Jared T.

Org Lett; 8(18): 3999-4002, 2006 Aug 31.

Artículo en Inglés | MEDLINE | ID: mdl-16928058

10.

X-ray crystal structures of Escherichia coli RNA polymerase with switch region binding inhibitors enable rational design of squaramides with an improved fraction unbound to human plasma protein.

Molodtsov, Vadim; Fleming, Paul R; Eyermann, Charles J; Ferguson, Andrew D; Foulk, Melinda A; McKinney, David C; Masse, Craig E; Buurman, Ed T; Murakami, Katsuhiko S.

J Med Chem; 58(7): 3156-71, 2015 Apr 09.

Artículo en Inglés | MEDLINE | ID: mdl-25798859

11.

C(2)-symmetric Sc(III)-complexes as chiral Lewis acids. Catalytic enantioselective aldol additions to glyoxylate esters.

Evans, David A; Masse, Craig E; Wu, Jimmy.

Org Lett; 4(20): 3375-8, 2002 Oct 03.

Artículo en Inglés | MEDLINE | ID: mdl-12323022

12.

A general method for the enantioselective synthesis of pantolactone derivatives.

Evans, David A; Wu, Jimmy; Masse, Craig E; MacMillan, David W C.

Org Lett; 4(20): 3379-82, 2002 Oct 03.

Artículo en Inglés | MEDLINE | ID: mdl-12323023

13.

A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of ß-Secretase.

Kaller, Matthew R; Harried, Scott S; Albrecht, Brian; Amarante, Patricia; Babu-Khan, Safura; Bartberger, Michael D; Brown, James; Brown, Ryan; Chen, Kui; Cheng, Yuan; Citron, Martin; Croghan, Michael D; Graceffa, Russell; Hickman, Dean; Judd, Ted; Kriemen, Chuck; La, Daniel; Li, Vivian; Lopez, Patricia; Luo, Yi; Masse, Craig; Monenschein, Holger; Nguyen, Thomas; Pennington, Lewis D; Miguel, Tisha San; Sickmier, E Allen; Wahl, Robert C; Weiss, Matthew M; Wen, Paul H; Williamson, Toni; Wood, Stephen; Xue, May; Yang, Bryant; Zhang, Jianhua; Patel, Vinod; Zhong, Wenge; Hitchcock, Stephen.

ACS Med Chem Lett; 3(11): 886-91, 2012 Nov 08.

Artículo en Inglés | MEDLINE | ID: mdl-24900403

14.

Total Synthesis of (+)-Mycotrienol and (+)-Mycotrienin I.

Panek, James S.; Masse, Craig E..

J Org Chem; 62(24): 8290-8291, 1997 Nov 28.

Artículo en Inglés | MEDLINE | ID: mdl-11671962

15.

Divergent structural complexity from a linear reaction sequence: synthesis of fused and spirobicyclic gamma-lactams from common synthetic precursors.

Masse, Craig E; Ng, Pui Yee; Fukase, Yoshiyuki; Sanchez-Roselló, María; Shaw, Jared T.

J Comb Chem; 8(3): 293-6, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16676997

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