Búsqueda | Portal de Búsqueda de la BVS España

1.

Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.

Shurtleff, Valerie W; Layton, Mark E; Parish, Craig A; Perkins, James J; Schreier, John D; Wang, Yunyi; Adam, Gregory C; Alvarez, Nadine; Bahmanjah, Soheila; Bahnck-Teets, Carolyn M; Boyce, Christopher W; Burlein, Christine; Cabalu, Tamara D; Campbell, Brian T; Carroll, Steven S; Chang, Wonsuk; de Lera Ruiz, Manuel; Dolgov, Enriko; Fay, John F; Fox, Nicholas G; Goh, Shih Lin; Hartingh, Timothy J; Hurzy, Danielle M; Kelly, Michael J; Klein, Daniel J; Klingler, Franca-Maria; Krishnamurthy, Harini; Kudalkar, Shalley; Mayhood, Todd W; McKenna, Philip M; Murray, Edward M; Nahas, Debbie; Nawrat, Christopher C; Park, Steven; Qian, Dongming; Roecker, Anthony J; Sharma, Vijeta; Shipe, William D; Su, Jing; Taggart, Robert V; Truong, Quang; Wu, Yin; Zhou, Xiaoyan; Zhuang, Ningning; Perlin, David S; Olsen, David B; Howe, John A; McCauley, John A.

J Med Chem; 67(5): 3935-3958, 2024 Mar 14.

Artículo en Inglés | MEDLINE | ID: mdl-38365209

2.

Antiviral activity and in vitro mutation development pathways of MK-6186, a novel nonnucleoside reverse transcriptase inhibitor.

Lu, Meiqing; Felock, Peter J; Munshi, Vandna; Hrin, Renee C; Wang, Ying-Jie; Yan, Youwei; Munshi, Sanjeev; McGaughey, Georgia B; Gomez, Robert; Anthony, Neville J; Williams, Theresa M; Grobler, Jay A; Hazuda, Daria J; McKenna, Philip M; Miller, Michael D; Lai, Ming-Tain.

Antimicrob Agents Chemother; 56(6): 3324-35, 2012 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-22391531

3.

Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase.

Hayes, Robert P; Heo, Mee Ra; Mason, Mark; Reid, John; Burlein, Christine; Armacost, Kira A; Tellers, David M; Raheem, Izzat; Shaw, Anthony W; Murray, Edward; McKenna, Philip M; Abeywickrema, Pravien; Sharma, Sujata; Soisson, Stephen M; Klein, Daniel.

Nat Commun; 12(1): 3040, 2021 05 24.

Artículo en Inglés | MEDLINE | ID: mdl-34031403

4.

Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen.

Bukhtiyarova, Marina; Cook, Erica M; Hancock, Paula J; Hruza, Alan W; Shaw, Anthony W; Adam, Gregory C; Barnard, Richard J O; McKenna, Philip M; Holloway, M Katharine; Bell, Ian M; Carroll, Steve; Cornella-Taracido, Ivan; Cox, Christopher D; Kutchukian, Peter S; Powell, David A; Strickland, Corey; Trotter, B Wesley; Tudor, Matthew; Wolkenberg, Scott; Li, Jing; Tellers, David M.

ACS Med Chem Lett; 12(1): 99-106, 2021 Jan 14.

Artículo en Inglés | MEDLINE | ID: mdl-33488970

5.

Distinct mutation pathways of non-subtype B HIV-1 during in vitro resistance selection with nonnucleoside reverse transcriptase inhibitors.

Lai, Ming-Tain; Lu, Meiqing; Felock, Peter J; Hrin, Renee C; Wang, Ying-Jie; Yan, Youwei; Munshi, Sanjeev; McGaughey, Georgia B; Tynebor, Robert M; Tucker, Thomas J; Williams, Theresa M; Grobler, Jay A; Hazuda, Daria J; McKenna, Philip M; Miller, Michael D.

Antimicrob Agents Chemother; 54(11): 4812-24, 2010 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-20805392

6.

Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor.

Lai, Ming-Tain; Munshi, Vandna; Touch, Sinoeun; Tynebor, Robert M; Tucker, Thomas J; McKenna, Philip M; Williams, Theresa M; DiStefano, Daniel J; Hazuda, Daria J; Miller, Michael D.

Antimicrob Agents Chemother; 53(6): 2424-31, 2009 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-19289522

7.

Mechanistic Study of Common Non-Nucleoside Reverse Transcriptase Inhibitor-Resistant Mutations with K103N and Y181C Substitutions.

Lai, Ming-Tain; Munshi, Vandna; Lu, Meiqing; Feng, MeiZhen; Hrin-Solt, Renee; McKenna, Philip M; Hazuda, Daria J; Miller, Michael D.

Viruses; 8(10)2016 09 23.

Artículo en Inglés | MEDLINE | ID: mdl-27669286

8.

Recombinant rhabdoviruses as potential vaccines for HIV-1 and other diseases.

McKenna, Philip M; McGettigan, James P; Pomerantz, Roger J; Dietzschold, Bernhard; Schnell, Matthias J.

Curr HIV Res; 1(2): 229-37, 2003 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-15043205

9.

HIV-1 vaccines: the search continues.

McGettigan, James P; McKenna, Philip M; Schnell, Matthias J.

Clin Lab Med; 22(3): 799-820, viii, 2002 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-12244598

10.

Assessment of the susceptibility of mutant HIV-1 to antiviral agents.

Wang, Ying-Jie; McKenna, Philip M; Hrin, Renee; Felock, Peter; Lu, Meiqing; Jones, Kristen G; Coburn, Craig A; Grobler, Jay A; Hazuda, Daria J; Miller, Michael D; Lai, Ming-Tain.

J Virol Methods; 165(2): 230-7, 2010 May.

Artículo en Inglés | MEDLINE | ID: mdl-20153375

11.

Highly attenuated rabies virus-based vaccine vectors expressing simian-human immunodeficiency virus89.6P Env and simian immunodeficiency virusmac239 Gag are safe in rhesus macaques and protect from an AIDS-like disease.

McKenna, Philip M; Koser, Martin L; Carlson, Kevin R; Montefiori, David C; Letvin, Norman L; Papaneri, Amy B; Pomerantz, Roger J; Dietzschold, Bernhard; Silvera, Peter; McGettigan, James P; Schnell, Matthias J.

J Infect Dis; 195(7): 980-8, 2007 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-17330788

12.

Immunogenicity of cytopathic and noncytopathic viral vectors.

Plesa, Gabriela; McKenna, Philip M; Schnell, Matthias J; Eisenlohr, Laurence C.

J Virol; 80(13): 6259-66, 2006 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-16775313

13.

Enhanced humoral HIV-1-specific immune responses generated from recombinant rhabdoviral-based vaccine vectors co-expressing HIV-1 proteins and IL-2.

McGettigan, James P; Koser, Martin L; McKenna, Philip M; Smith, Mary Ellen; Marvin, Julie M; Eisenlohr, Laurence C; Dietzschold, Bernhard; Schnell, Matthias J.

Virology; 344(2): 363-77, 2006 Jan 20.

Artículo en Inglés | MEDLINE | ID: mdl-16226782

14.

Strong cellular and humoral anti-HIV Env immune responses induced by a heterologous rhabdoviral prime-boost approach.

Tan, Gene S; McKenna, Philip M; Koser, Martin L; McLinden, Robert; Kim, Jerome H; McGettigan, James P; Schnell, Matthias J.

Virology; 331(1): 82-93, 2005 Jan 05.

Artículo en Inglés | MEDLINE | ID: mdl-15582655

15.

Covalently linked human immunodeficiency virus type 1 gp120/gp41 is stably anchored in rhabdovirus particles and exposes critical neutralizing epitopes.

McKenna, Philip M; Pomerantz, Roger J; Dietzschold, Bernhard; McGettigan, James P; Schnell, Matthias J.

J Virol; 77(23): 12782-94, 2003 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-14610200

16.

Functional human immunodeficiency virus type 1 (HIV-1) Gag-Pol or HIV-1 Gag-Pol and env expressed from a single rhabdovirus-based vaccine vector genome.

McGettigan, James P; Naper, Kristin; Orenstein, Jan; Koser, Martin; McKenna, Philip M; Schnell, Matthias J.

J Virol; 77(20): 10889-99, 2003 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-14512539

17.

Immunogenicity study of glycoprotein-deficient rabies virus expressing simian/human immunodeficiency virus SHIV89.6P envelope in a rhesus macaque.

McKenna, Philip M; Aye, Pyone Pyone; Dietzschold, Bernhard; Montefiori, David C; Martin, Louis N; Marx, Preston A; Pomerantz, Roger J; Lackner, Andrew; Schnell, Matthias J.

J Virol; 78(24): 13455-9, 2004 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-15564456

18.

Second-generation rabies virus-based vaccine vectors expressing human immunodeficiency virus type 1 gag have greatly reduced pathogenicity but are highly immunogenic.

McGettigan, James P; Pomerantz, Roger J; Siler, Catherine A; McKenna, Philip M; Foley, Heather D; Dietzschold, B; Schnell, Matthias J.

J Virol; 77(1): 237-44, 2003 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-12477829

Portal de Búsqueda de la BVS España

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: