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1.
Common dihydropyrimidinase ( DPYS ) genetic variations do not predict fluoropyrimidine-related chemotherapy toxicity in a Canadian cohort.
Pharmacogenet Genomics;
34(3): 83-87, 2024 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38215018
2.
Differential effects of OATP2B1 on statin accumulation and toxicity in a beta cell model.
Toxicol Mech Methods;
34(2): 130-147, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37771097
3.
Impact of organic anion transporting polypeptide, P-glycoprotein, and breast cancer resistance protein transporters on observed tamoxifen and endoxifen concentration and adverse effects.
Pharmacogenet Genomics;
33(1): 10-18, 2023 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36373739
4.
Genetic Variation in miR-27a Is Associated with Fluoropyrimidine-Associated Toxicity in Patients with Dihydropyrimidine Dehydrogenase Variants after Genotype-Guided Dose Reduction.
Int J Mol Sci;
24(17)2023 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37686089
5.
In-vitro characterization of coding variants with predicted functional implications in the efflux transporter multidrug resistance protein 4 (MRP4, ABCC4).
Pharmacogenet Genomics;
32(3): 111-116, 2022 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34693929
6.
Implementation of pharmacogenomics: Where are we now?
Br J Clin Pharmacol;
2022 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36366858
7.
Bisphenol A stimulates steroidogenic acute regulatory protein expression via an unknown mechanism in adrenal cortical cells.
J Cell Biochem;
120(2): 2429-2438, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30206973
8.
Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1.
Drug Metab Dispos;
47(8): 832-842, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31123035
9.
Impact of CYP2C19 metabolizer status on esophageal mucosal inflammation, acid exposure, and motility among patients on chronic proton-pump inhibitor therapy with refractory symptoms of gastroesophageal reflux disease.
J Can Assoc Gastroenterol;
7(3): 238-245, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38841142
10.
Fluoropyrimidine-associated toxicity and DPYD variants c.85T>C, c.496A>G, and c.1236G>A: impact of haplotype.
Cancer Chemother Pharmacol;
91(1): 97-102, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36357798
11.
DPYD Exon 4 Deletion Associated with Fluoropyrimidine Toxicity and Importance of Copy Number Variation.
Curr Oncol;
30(1): 663-672, 2023 01 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36661700
12.
Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates.
Front Pharmacol;
12: 713567, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34594217
13.
Impact of pretreatment dihydropyrimidine dehydrogenase genotype-guided fluoropyrimidine dosing on chemotherapy associated adverse events.
Clin Transl Sci;
14(4): 1338-1348, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33620159
14.
Bisphenol A stimulates adrenal cortical cell proliferation via ERß-mediated activation of the sonic hedgehog signalling pathway.
J Steroid Biochem Mol Biol;
178: 254-262, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29307715
15.
Prenatal exposure to bisphenol A disrupts adrenal steroidogenesis in adult mouse offspring.
Environ Toxicol Pharmacol;
43: 203-8, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27017381
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