Exploring Biomechanical Correlates in Voice Analysis of Multiple Sclerosis Patients.

INTRODUCTION: The predominant alterations in voice of patients with Multiple Sclerosis (MS) are phonatory instability, vocal asthenia and roughness, shortness of breath, hypophonia and hypernasality. However, research on alterations of acoustic parameters has few studies and disparate results. To investigate voice disturbances in patients with MS; both with objective measures (analysis of biomechanical) and subjective measures (scales and questionnaires). METHODS: Experimental study with a total of 20 participants with MS. Voice samples were collected, and biomechanical correlates were analyzed through the Clinical Voice Systems program, Online Lab APP. The VHI-30 (Voice Handicap Index) questionnaire, the GRBAS (grade, roughness, breathiness, asthenia, strain) scale and the Hospital Anxiety and Depression Scale were used as subjective measures. RESULTS: 95% of participants feel and describe dysphonic difficulties. Self-perception of vocal disability correlated with auditory vocal perceptual analysis in the sample of women. CONCLUSION: The biomechanical parameters showed alterations in the strength of the glottic closure, in the efficiency index and in the structural imbalance index.

Naive skepticism scale: development and validation tests applied to the chilean population.

BACKGROUND: Skepticism has traditionally been associated with critical thinking. However, philosophy has proposed a particular type of skepticism, termed naive skepticism, which may increase susceptibility to misinformation, especially when contrasting information from official sources. While some scales propose to measure skepticism, they are scarce and only measure specific topics; thus, new instruments are needed to assess this construct. OBJECTIVE: This study aimed to develop a scale to measure naive skepticism in the adult population. METHOD: The study involved 446 individuals from the adult population. Subjects were randomly selected for either the pilot study (phase 2; n = 126) or the validity-testing study (phase 3; n = 320). Parallel analyses and exploratory structural equation modelling were conducted to assess the internal structure of the test. Scale reliability was estimated using Cronbach's alpha and McDonald's omega coefficients Finally, a multigroup confirmatory factor analysis was performed to assess invariance, and a Set- Exploratory Structural Equation Modeling was applied to estimate evidence of validity based on associations with other variables. RESULTS: The naive skepticism scale provided adequate levels of reliability (ω > 0.8), evidence of validity based on the internal structure of the test (CFI = 0.966; TLI = 0.951; RMSEA = 0.079), gender invariance, and a moderate inverse effect on attitudes towards COVID-19 vaccines. CONCLUSIONS: The newly developed naive skepticism scale showed acceptable psychometric properties in an adult population, thus enabling the assessment of naive skepticism in similar demographics. This paper discusses the implications for the theoretical construct and possible limitations of the scale.

The Effects of Social Determinants and Resilience on the Mental Health of Chilean Adolescents.

The aim of this research was to evaluate the effects of social determinants (i.e., gender, educational vulnerability, and socioeconomic status) and resilience on the mental health of Chilean adolescents in pre-, during, and post-COVID-19 pandemic contexts. The study included a group of 684 students, ranging in age from 12 to 18 years, who were attending educational institutions in the city of Arica. The Child and Adolescent Assessment System (SENA) was used to measure mental health problems, the Brief Resilience Scale for Children and Youth (CYRM-12) was used to measure resilience, and the Vulnerability Index of Educational Institutions was used to measure educational vulnerability. The results suggest increases in depressive, anxious, and social anxiety symptomatologies over time (wave by year, 2018, 2020, and 2021). In addition, multiple linear regression models showed predictive effects of the COVID-19 pandemic, gender, vulnerability index, socioeconomic status, and resilient behaviors on mental health problems. The worsening of mental health indicators over time requires the greater coordination and integration of mental health experts in the most vulnerable educational centers.

Pre and Post Pandemic Depressive and Anxious Symptoms in Children and Adolescents in Northern Chile.

The psychological effects of the COVID-19 pandemic still represent a focus of concern, especially in children and adolescents who are a group particularly vulnerable to the psychological consequences of the COVID-19 pandemic, mainly due to the loss of socialization and leisure spaces. The aim of the study is to determine the variation in the levels of depressive and anxious symptomatology in children and adolescents in the North of Chile. METHODS: A Repeated cross-sectional design (RCS) was used. The sample consisted of a total of 475 students aged 12 to 18 years (high school) from educational establishments in the city of Arica. To evaluate the changes in the mental health of students associated with the COVID-19 pandemic, the same mental health measures applied to students were compared in two waves (2018-2021). RESULTS: An increase in the symptomatology levels of depression, anxiety, social anxiety, and problems with the family, while a decrease in problems with school and peers was observed. CONCLUSIONS: The results show that there is an increase in mental health problems associated with the periods of time in which the COVID-19 pandemic transformed the social relation spaces and classrooms of secondary school students. The observed changes point to future challenges, which include that it may be important to improve the coordination and integration of mental health professionals in educational centers and schools.

The use of transcutaneous Vagal Nerve Stimulation as an effective countermeasure for Simulator Adaptation Syndrome.

This research focused on investigating the effectiveness of Transcutaneous Vagal Nerve Stimulation (tVNS) as compared to Galvanic Cutaneous Stimulation (GCS) at mitigating Simulator Adaptation Syndrome (SAS). Fifty drivers (mean age = 23.04 ± 17.71 years old, twenty-two men) participated in a driving simulation experiment. The total scores of the Simulator Sickness Questionnaire, head movements (body balance index), and driving performance variables were measured under five stimulation conditions: i) baseline (no stimulation delivered), ii) sham GCS, iii) sham tVNS, iv) active GCS, and v) active tNVS. The results showed that tVNS alleviated SAS and improved driving performance variables more effectively than GCS. We conclude that GCS and tVNS have similar neurological mechanisms to reduce SAS, providing possible explanations for the greater effectiveness of tVNS. We encourage the use of tVNS to decrease SAS.

Academic psychological capital questionnaire 12 (APCQ-12): psychometric validity and measurement invariance in a Chilean sample of high school students.

The present study evaluated the psychometric properties of the Academic Psychological Capital Questionnaire 12 (APCQ-12) in a sample of 2,196 Chilean high school students (51% girls) aged 12 to 17 years (mean 14.83 years). Results showed that: (1) the APCQ-12 produces adequate scores in terms of reliability, (2) the internal structure of the questionnaire obtains adequate fit indices, for a second order model, which is consistent with previous research, and (3) the APCQ-12 proved to be sex and age invariant. Overall, the APCQ-12 proved to be an adequate questionnaire for measuring academic psychological capital in Chilean high school students, producing valid and reliable scores.

Mental Health in Indigenous Children and Adolescents: The Contribution of Cultural Backgroud.

The purpose of this study is to describe and compare the prevalence of mental health problems in Aymara and non-Aymara children and adolescent. The study sample comprised 1839 students from 8 to 19 years, from educational institutions of Northern Chile. Forty-nine percent of students identified with the Aymara ethnic group. The Child and Adolescent Evaluation System was used to evaluate internal and external problems. In Elementary school, Aymara students showed significantly lower scores in externalized problems and in high school, there were significantly lower scores in interiorized, exteriorized and other problems than Non-Aymara students. It seems that the legacy of the Aymara culture has favored the development of protective factors in relation to the mental health of these students. In a context of growing recognition and appreciation of this culture, greater involvement with Aymara culture could promote better mental health of school children.

Psychological Factors and Sexual Risk Behaviors: A Multidimensional Model Based on the Chilean Population.

Human immunodeficiency virus (HIV) is a global health problem, with sexual risk behaviors (SRB) being the main routes of spreading the virus. Evidence indicates that different psychological factors influence SRB (e.g., attitude towards condoms, sexual self-concept, sexual sensation seeking, knowledge of sexual risk behaviors, risk perception). This study proposes an explanatory model of sexual risk behaviors in young people and adults. The sample consisted of 992 young people and adults aged between 18 and 35 years. The model presented good levels of fit (X2 = 3311.433, df = 1471, CFI = 0.964, TLI = 0.959, RMSEA = 0.036), explaining 56% of the variance of sexual activity with multiple partners, 77% of the inadequate use of protective barriers, and 58.8% of sexual activity under the influence of alcohol or drugs from a set of psychological factors in self-report measures. The details of the results offer novel contextual evidence for the prioritization of prevention-oriented psychosocial interventions.

Flourishing Scale: Adaptation and Evidence of Validity in a Chilean High School Context.

This study aimed to adapt the Flourishing Scale to a Chilean high school context and provide evidence of its validity. Data were collected from 1,348 students (52% girls) from three different Chilean schools. The results of confirmatory factor analysis (CFA) supported a one-factor solution, multiple-group CFA supported gender invariance, and structural equation model indicated that the FS is related to positive and negative academic feelings. Overall, the evidence indicates that the Flourishing Scale adapted to the high school context is an instrument that produces valid and reliable scores in our high school Chilean sample.

Development and Evidence of the Validity of the Condom Use Attitudes Scale for Youth and Adults in a Chilean Context.

Condom use is the most effective preventive behavior against HIV transmission, and its inadequate use is a public health problem that occurs mostly among youth and young adults. Although there are scales that measure condom use, those that exist correspond to English-speaking developments or do not have psychometric evidence to support them, so it is possible that the available adaptations of instruments do not adequately reflect the phenomenon in the Chilean population. Thus, the study aims to develop a scale to assess attitudes toward condom use in Chilean youth and young adults. Initially, a sample of students between 18 and 39 years (n = 520) was used for debugging the instrument. Then, a second sample was taken from the general population aged 18 to 40 (n = 992) to confirm the factor structure of the proposed model. The final scale has 10 items and 3 attitudinal dimensions (affective, cognitive, and behavioral). The results show that the identified structure provides adequate levels (ω > 0.7) or at least sufficient of reliability (ω > 0.6) and presents evidence of validity, based on the internal structure of the test, through ESEM (CFI = 0.993; TLI = 0.984; RMSEA = 0.056). In addition, evidence of validity was obtained based on the relationship with other variables and strong invariance between the scores of men and women. It is concluded that the scale developed has adequate psychometric properties to assess, in brief form, condom use attitudes in equal samples for research and screening purposes.

Effects of Adherence to Pharmacological Treatment on the Recovery of Patients with Schizophrenia.

The aim of this study was to evaluate the effects of adherence to antipsychotic treatment on the recovery of patients with schizophrenia in northern Chile. One hundred and fifty-one patients diagnosed with schizophrenia completed the Drug Attitude Inventory (DAI-10), Positive and Negative Syndrome Scale for Schizophrenia (PANSS), Recovery Assessment Scale (RAS-24), sociodemographic information, and clinical and treatment characteristics of patients with schizophrenia. Multivariate analysis with multiple linear regression was then performed to identify variables that were potentially associated with the recovery assessment (variable criterion). A significant association was found between adherence to antipsychotic medication and the Willing to Ask for Help dimension of Recovery (ß = 0.239, p = 0.005). Association of clinical and socio-demographic variables with recovery were identified: negative symptoms with Personal Confidence and Hope (ß = -0.341, p = 0.001) and Goal and Success Orientation (ß = -0.266, p = 0.014); cognitive symptoms with Willing to Ask for Help (ß = -0.305, p = 0.018) and no domination by symptoms (ß = -0.351, p = 0.005); marital status with reliance on others (ß = -0.181, p = 0.045); age with Personal Confidence and Hope (ß = -0.217, p = 0.021), Goal and Success Orientation (ß = -0.296, p = 0.003), and no domination by symptoms (ß = 0.214, p = 0.025). Adherence has a positive relationship with personal recovery in this sample of Chilean patients with schizophrenia.

School Burnout Inventory: Factorial Validity, Reliability, and Measurement Invariance in a Chilean Sample of High School Students.

This brief report assessed the psychometric validity and gender invariance of the School Burnout Inventory (SBI) -a measure of students' exhaustion, cynicism, and inadequacy- in a convenience sample of 972 high school Chilean students ranging between 12 and 18 years old. The results showed that: (1) the SBI produces adequate scores in terms of reliability; (2) two models (one solution of three related factors and one of second-order and three first-order factors) fitted adequately fit to our sample and was invariant across gender; and (3) the SBI scores were significantly related to other related constructs (i.e., study-related emotions, academic psychological capital, and academic engagement). Overall, the SBI was found to be a reliable and valid inventory to assess school burnout in Chilean high school students.

Relationship between Everyday Discrimination and Substance Use among Adolescents in Northern Chile.

Substance use is a public health problem that affects the normal physical, neurological, and psychological development of adolescents. Apparently, discrimination is an important variable for explaining the initiation and continued use of alcohol and marijuana. Since most research focused on discrimination based on factors, such as race, ethnicity, sexual orientation, or gender faced by minority groups, studies on discrimination faced by the general population remain scarce. This cross-sectional study described the relationship between everyday discrimination and alcohol and marijuana use-related behaviors among Chilean adolescents. It included 2330 students between 12 and 20 years of age from educational establishments in the city of Arica. To evaluate substance use, specifically alcohol and marijuana, the Child and Adolescent Evaluation System (SENA) was used. The Everyday Discrimination scale was used to evaluate discrimination. Age and everyday discrimination can predict up to 11% of the variance in substance use. Reducing the incidence of everyday discrimination may help reduce heavy alcohol and marijuana consumption among adolescents.

Effects of Resilience and Acculturation Stress on Integration and Social Competence of Migrant Children and Adolescents in Northern Chile.

Migration in Chile has increased exponentially in recent years, with education being one of the main focuses of attention in this cultural transformation. Integration and social competence in the migrant population are determined by several factors. The aim of this study is to evaluate the potential effects of resilience and acculturation stress on the levels of integration and social competence in migrant students in Northern Chile. In total, 292 school children of both genders aged 8 to 18, from the fourth grade to senior year of high school, participated in the investigation. A subscale of the Child and Adolescent Assessment System (Sistema de evaluación de niños y adolescentes SENA) was used to assess integration and social competence. Additionally, the Child and Youth Resilience Measure (CYRM-12) and the Acculturation Stress Source Scale (FEAC) were used. The results show that integration and social competence have statistically significant and direct associations with resilience (p < 0.001) and indirect associations with acculturation stress (p = 0.009). Both constructs could be defined as protection and risk factors, respectively, and should be considered in educational contexts to favor adaptation in the integration of migrant children and adolescents.

Adherence to Antipsychotic Medication and Quality of Life in Latin-American Patients Diagnosed with Schizophrenia.

PURPOSE: The purpose of this study was to describe the association between adherence to antipsychotic medication and quality of life (QoL) in a sample of individuals diagnosed with schizophrenia. METHODS: Two hundred fifty-three patients were included from three public mental health services from Bolivia, Peru, and Chile. Data were collected using the Drug Attitude Inventory (DAI-10) and the Schizophrenia Quality of Life short-version questionnaire (SQoL-18), which considers 8 dimensions. RESULTS: Significant associations were found between adherence to antipsychotic medication treatment and QoL (S-QoL-18 index: ß = 0.26, p = 0.004; self-esteem: ß = 0.37, p = 0.000; and sentimental life: ß = 0.20, p = 0.033). Associations of clinical and socio-demographic variables with QoL were identified: severity of psychotic symptoms, awareness of the disease, gender, age, and ethnicity were found to be associated with a lower level of QoL (ß from 0.14 -0.56). CONCLUSION: This study provides evidence of the association between adherence to treatment and quality of life in patients diagnosed with schizophrenia. Therefore, as in developed countries, improving adherence to antipsychotic medication would appear to be an important issue to address to improve patients' QoL in Latin American countries.

Development and evidence of validity of the HIV risk perception scale for young adults in a Hispanic-American context.

HIV/AIDS is a public health problem that is transmitted through risky sexual behavior. The literature suggests that the perception of HIV risk is a motivator for the prevention of risky sexual behaviors. There is no culturally adapted scale to assess HIV risk perception in the Hispanic-American population. The aim of this research was to develop a scale to assess HIV risk perception in Hispanic-American young adults. A cross-sectional instrumental design was used, with a sample of students from the Chilean city with the highest HIV rates. Participants (n = 524) were between 18 and 33 years old, of whom 51% were women, 84.4% said they were heterosexual and 43.7% said they had not been tested for HIV/AIDS. The final scale has 9 items and 2 dimensions: (1) perceived risk susceptibility and (2) perceived risk severity. The results showed that the identified structure provided adequate levels of reliability (ω > .8) and presented evidence of validity, based on the internal structure of the test (i.e., using ESEM) and on the relationship with other variables (i.e., the sexual risk behaviors scale). In addition, the results showed strong invariance between the scores for men and women. It is concluded that the HIV risk perception scale has adequate psychometric properties to assess HIV risk perception in equivalent samples.

Correction: Development and evidence of validity of the HIV risk perception scale for young adults in a Hispanic-American context.

[This corrects the article DOI: 10.1371/journal.pone.0231558.].

Naive skepticism scale: development and validation tests applied to the chilean population

Abstract Background Skepticism has traditionally been associated with critical thinking. However, philosophy has proposed a particular type of skepticism, termed naive skepticism, which may increase susceptibility to misinformation, especially when contrasting information from official sources. While some scales propose to measure skepticism, they are scarce and only measure specific topics; thus, new instruments are needed to assess this construct. Objective This study aimed to develop a scale to measure naive skepticism in the adult population. Method The study involved 446 individuals from the adult population. Subjects were randomly selected for either the pilot study (phase 2; n = 126) or the validity-testing study (phase 3; n = 320). Parallel analyses and exploratory structural equation modelling were conducted to assess the internal structure of the test. Scale reliability was estimated using Cronbach's alpha and McDonald's omega coefficients Finally, a multigroup confirmatory factor analysis was performed to assess invariance, and a Set- Exploratory Structural Equation Modeling was applied to estimate evidence of validity based on associations with other variables. Results The naive skepticism scale provided adequate levels of reliability (ω > 0.8), evidence of validity based on the internal structure of the test (CFI = 0.966; TLI = 0.951; RMSEA = 0.079), gender invariance, and a moderate inverse effect on attitudes towards COVID-19 vaccines. Conclusions The newly developed naive skepticism scale showed acceptable psychometric properties in an adult population, thus enabling the assessment of naive skepticism in similar demographics. This paper discusses the implications for the theoretical construct and possible limitations of the scale.

Validación de la escala GEOPTE de cognición social para psicosis en pacientes con esquizofrenia en Latinoamérica / Validation of the GEOPTE scale of social cognition for psychosis in patients with schizophrenia in Latin America

El propósito de este estudio fue validar la escala GEOPTE de cognición socialpara su uso en pacientes con diagnóstico de esquizofrenia en paísesLatinoamericanos. Participaron 253 pacientes con un diagnóstico de esquizofreniay 253 cuidadores principales provenientes de los servicios públicos de salud mentalde Bolivia, Chile y Perú. Las propiedades psicométricas de la escala GEOPTE fueronobtenidas mediante análisis factoriales confirmatorios (CFA), CFA-multigrupo,coeficientes de fiabilidad y correlación de Pearson. El CFA mostró la adecuaciónentre la estructura factorial teórica original con la establecida en este estudio devalidación. La escala evidenció satisfactorios indicadores de fiabilidad, presentóasociaciones significativas con la “Escala de los síndromes positivo y negativo”(PANSS) y sólo mostró invarianza débil según el sexo. La escala GEOPTE poseepruebas de validez y fiabilidad suficiente para su uso en pacientes con diagnósticode esquizofrenia en países Latinoamericanos. (AU)

The purpose of this study was to validate the GEOPTE scale of social cognitionfor its use in patients diagnosed with Schizophrenia in Latin American countries.The participants were 253 patients with a diagnosis of Schizophrenia and 253 maincaregivers from mental health services in Bolivia, Chile and Peru. The psychometricproperties of the GEOPTE scale were obtained through confirmatory factor analysis(CFA), CFA-multigroup, reliability coefficients and Pearson's correlation. The CFAshowed the adequacy between the original theoretical factor structure and the oneestablished in this validation study. The scale showed satisfactory reliabilityindicators, presented significant associations with the Positive and NegativeSyndrome Scale (PANSS) and showed only weak invariance according to gender.The GEOPTE scale has sufficient evidence of validity and reliability for its use inpatients diagnosed with Schizophrenia in Latin American countries. (AU)