RESUMEN
Twelve medicinal plants used popularly for their reputed analgesic properties were tested in mice by the writhing and tail-flick methods. All extractions were made using 50% aqueous ethanol at low temperatures. The oral dose administered was always 1 g solids/kg. While several extracts showed a positive effect in one of the tests, significant effects in both tests were produced by Serjania communis only. Morphine and acetylsalicylic acid were used as reference drugs.
Asunto(s)
Analgésicos/farmacología , Plantas Medicinales/análisis , Abdomen/efectos de los fármacos , Analgésicos/aislamiento & purificación , Animales , Brasil , Evaluación Preclínica de Medicamentos , Etanol , Femenino , Ratones , Dolor/prevención & control , Cola (estructura animal)/efectos de los fármacos , TemperaturaRESUMEN
Seventeen medicinal plants used popularly in Brazil for their reputed analgesic properties were tested in mice by the writhing and tail flick methods. All extractions were made in 50% aqueous ethanol at low temperatures. The oral dose administered was always 1 g extract/kg. Significant effects in both tests were produced by Lippia alba, Piper abutiloides, Piper cincinnatoris, Piper lindbergii and Tillandsia usneoides.