RESUMEN
A 15-month-old boy presented with new onset symmetric erythema of the conchal bowls bilaterally in the setting of treatment with cytarabine. Findings were consistent with a diagnosis of toxic erythema of chemotherapy, an adverse effect of chemotherapy. In this report, we detail this uncommon manifestation in a young child along with a brief literature review of the background, pathophysiology, and treatment strategies of toxic erythema of chemotherapy to increase awareness of this presentation in pediatric populations.
Asunto(s)
Citarabina , Eritema , Niño , Citarabina/efectos adversos , Eritema/inducido químicamente , Humanos , Lactante , MasculinoRESUMEN
The present report documents 6 patients who developed distinctive hyperpigmented skin lesions after bleomycin sclerotherapy for vascular malformations of the face, neck, and extremities. The patients ranged in age from 2 to 65 years and included both black and white and male and female patients. The bleomycin treatment dose varied from 15 to 45 U, with 5 of the 6 patients receiving foamed bleomycin. The hyperpigmented lesions were near the patient's vascular anomaly and attributable to postprocedural cutaneous pressure (eg, electrocardiographic [ECG] leads or tape). Hyperpigmentation faded slowly over time but was visible up to 3 years after the procedure.
Asunto(s)
Bleomicina/efectos adversos , Hiperpigmentación/inducido químicamente , Soluciones Esclerosantes/efectos adversos , Escleroterapia/efectos adversos , Pigmentación de la Piel/efectos de los fármacos , Malformaciones Vasculares/terapia , Adolescente , Anciano , Niño , Preescolar , Femenino , Humanos , Hiperpigmentación/diagnóstico , Hiperpigmentación/fisiopatología , Masculino , Persona de Mediana Edad , Resultado del Tratamiento , Adulto JovenAsunto(s)
Enfermedades de la Uña , Uñas , Humanos , Fenómenos Magnéticos , Enfermedades de la Uña/patología , Uñas/patologíaAsunto(s)
Alcaptonuria/patología , Ocronosis/patología , Piel/patología , Femenino , Humanos , Persona de Mediana EdadRESUMEN
Introduction: Cuticle reduction and removal techniques are commonly performed by nail technicians for nail cosmesis. However, manipulation of the nail cuticle can lead to localized infection and nail dystrophy. Case Presentation: In this case, a 20-year-old woman from the Philadelphia area in the USA presented with onychomadesis secondary to acute paronychia following a "Russian" manicure. In this technique, an electronic filer is used to completely remove the cuticle, leaving the proximal nail fold exposed and vulnerable. Conclusion: As this style of manicure is being inaccurately publicized as safe, it is important that dermatologists are aware of this technique and educate our patients about its potential for harm.
RESUMEN
In 1981, the HIV/AIDS epidemic was first recognized in young gay men presenting with opportunistic infections and Kaposi sarcoma. Over the past 40 years, there has been an unparalleled and hugely successful effort on the part of physicians, scientists, public health experts, community activists, and grassroots organizations to study, treat, and prevent HIV/AIDS. Yet the role of dermatologists in the investigation of HIV/AIDS and in the treatment of infected patients has largely been neglected in the historical literature. It is important to revisit dermatologists' historic contributions and problematic biases during this epidemic and honor the legacy of the dermatologists who were instrumental in treating and advocating for patients affected by HIV/AIDS.
Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/historia , Dermatólogos/historia , Infecciones por VIH/historia , Síndrome de Inmunodeficiencia Adquirida/epidemiología , Aniversarios y Eventos Especiales , Dermatólogos/organización & administración , Dermatología/historia , Infecciones por VIH/epidemiología , Historia del Siglo XX , Humanos , Rol del Médico/historiaRESUMEN
Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Although the exact pathogenesis of PR is unknown, current evidence suggests that an inflammatory reaction due to a viral trigger may lead to the cutaneous manifestations. COVID-19 has been reported as one such viral trigger for PR. Previously, PR has been reported in temporal association with various viral inoculations. This article presents a case of PR in a 66-year-old black male 1 week after administration of the Pfizer-BioNTech COVID-19 vaccine.