Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
1.
Pediatr Emerg Care ; 31(10): 717-9, 2015 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-26427946

RESUMEN

A 9-year-old boy presented with acute onset of abdominal pain and vomiting. History, physical examination, and initial laboratory testing failed to provide a diagnosis. A computed tomography scan revealed the rare finding of epiploic appendagitis. We review the literature of this rare, but increasingly recognized, condition that mimics appendicitis and needs to be considered in the child with acute abdominal pain.


Asunto(s)
Abdomen Agudo/etiología , Apendicitis/diagnóstico , Abdomen Agudo/patología , Apendicitis/patología , Niño , Diagnóstico Diferencial , Humanos , Masculino , Tomografía Computarizada por Rayos X
2.
Ann Pharmacother ; 48(1): 137-41, 2014 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-24259612

RESUMEN

OBJECTIVE: To report a case describing resolution of persistently elevated aminotransferases in a patient with severe, resistant nonalcoholic fatty liver disease (NAFLD) using combination therapy. CASE SUMMARY: A 47-year-old obese male patient presented with a history of elevated aminotransferases and numerous statin intolerances. In addition to worsening control of diabetes and dyslipidemia, severe NAFLD was confirmed. Rosuvastatin was started, which induced short-term elevations in aminotransferases resulting in patient discontinuation. Biochemical markers of NAFLD worsened over time. Therefore, both rosuvastatin 20 mg daily and pioglitazone 15 mg daily were started simultaneously to potentially blunt the early increase in transaminases seen with rosuvastatin. At 2 weeks, the patient's alanine aminotransferase (ALT) and aspartate aminotransferase (AST) had decreased 57% and 56% from baseline, respectively. By 9 months, the patient's ALT and AST serum concentrations had normalized. Repeat liver ultrasound demonstrated improvement in steatosis grading and reduction in liver size. These improvements occurred despite a 4.5-kg weight gain since starting rosuvastatin and pioglitazone. DISCUSSION: Pharmacotherapy in NAFLD is not well validated, particularly combination therapy. Medications that target obesity-related consequences are commonly used, although evidence regarding biochemical and histological improvement is inconclusive. Consideration should be given to the use of combination of thiazolidinediones and statins for rapid biochemical improvement and long-term histological impact. CONCLUSIONS: The improvement in this patient's biochemical and ultrasonographic markers of resistant, severe NAFLD was rapid and sustained with combination therapy. This case represents a potential solution for initiating or maintaining statin therapy in patients with NAFLD who are at high cardiovascular risk.


Asunto(s)
Hígado Graso/tratamiento farmacológico , Fluorobencenos/administración & dosificación , Inhibidores de Hidroximetilglutaril-CoA Reductasas/administración & dosificación , Hipoglucemiantes/administración & dosificación , Pirimidinas/administración & dosificación , Sulfonamidas/administración & dosificación , Tiazolidinedionas/administración & dosificación , Alanina Transaminasa/sangre , Aspartato Aminotransferasas/sangre , Diabetes Mellitus Tipo 2/sangre , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Resistencia a Medicamentos , Quimioterapia Combinada , Dislipidemias/sangre , Dislipidemias/tratamiento farmacológico , Hígado Graso/sangre , Humanos , Hipertensión/sangre , Hipertensión/tratamiento farmacológico , Masculino , Síndrome Metabólico/sangre , Síndrome Metabólico/tratamiento farmacológico , Persona de Mediana Edad , Enfermedad del Hígado Graso no Alcohólico , Obesidad/sangre , Obesidad/tratamiento farmacológico , Pioglitazona , Rosuvastatina Cálcica
4.
J Vasc Surg Cases ; 1(2): 100-101, 2015 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31724609

RESUMEN

We present a case of pericardial effusion due to embolization of a fragment of an inferior vena cava (IVC) filter, with subsequent perforation of the right ventricle. This is a rare and unexpected cause of pericardial effusion. Fracture or embolization of IVC filters is a relatively uncommon complication, but these events may have serious clinical implications. Although IVC filters are often placed with the intent of removal, the device in many patients is never removed. The long-term implications of IVC filter placement must be kept in mind when making decisions about device placement and subsequent removal.

SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA