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1.
Pak J Biol Sci ; 13(8): 362-8, 2010 Apr 15.
Artículo en Inglés | MEDLINE | ID: mdl-20836295

RESUMEN

The present study aimed to test the validity of Balanites aegyptiaca remedies used for the treatment of rheumatisms and mental disorders by examining the antioxidant, xanthine oxidase and acetylcholinesterase inhibitory activities of galls and leaves extracts and fractions. The total phenolics and flavonoids were measured using Folin-Ciocalteu and AlCl3 reagents, respectively. Two methods i.e., FRAP and ABTS were used to estimate the total antioxidant capacity of the plant materials. The FRAP and ABTS antioxidant activities showed that among all extracts and fractions tested, the best antioxidant activities were found with the galls dichloromethane and the leaves ethyl acetate fractions. The antioxidant activities did correlated significantly with the total phenolic and flavonoid contents. The study also showed that B. aegyptiaca galls and leaves fractions exhibited a moderate xanthine oxidase inhibitory activity comparatively to the acetylcholinesterase which was weakly inhibited by the tested extracts and fractions.


Asunto(s)
Acetilcolina/metabolismo , Antioxidantes/metabolismo , Balanites , Inhibidores de la Colinesterasa/metabolismo , Extractos Vegetales/metabolismo , Xantina Oxidasa , Animales , Balanites/química , Balanites/metabolismo , Flavonoides/aislamiento & purificación , Flavonoides/metabolismo , Humanos , Fenoles/aislamiento & purificación , Fenoles/metabolismo , Extractos Vegetales/uso terapéutico , Reproducibilidad de los Resultados , Xantina Oxidasa/antagonistas & inhibidores , Xantina Oxidasa/metabolismo
2.
Pak J Biol Sci ; 13(22): 1092-8, 2010 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-21313883

RESUMEN

In this study polyphenol content, antioxidant activity, lipoxygenase (LOX) and Xanthine Oxidase (XO) inhibitory effects of n-hexane, dichloromethane, ethyl acetate and n-butanol fractions of aqueous acetone extracts from S. alba L., S. acuta Burn f and Cienfuegosia digitata Cav. were investigated. The total phenolics, flavonoids, flavonols and total tannins were determined by spectrophotometric methods using Folin-ciocalteu, AlCl3 reagents and tannic acid, respectively. The antioxidant potential was evaluated using three methods: inhibition of free radical 2,2-diphenyl-1-picrylhydramzyl (DPPH), ABTS radical cation decolorization assay and Iron (III) to iron (II) reduction activity (FRAP). For enzymatic activity, lipoxygenase and xanthine oxidase inhibitory activities were used. This study shows a relationship between polyphenol contents, antioxidant and enzymatic activities. Present results showed that ethyl acetate and dichloromethane fractions elicit the highest polyphenol content, antioxidant and enzymatic activities.


Asunto(s)
Antioxidantes/farmacología , Lipooxigenasas/efectos de los fármacos , Malvaceae/química , Xantina Oxidasa/antagonistas & inhibidores
3.
Pak J Biol Sci ; 12(14): 1004-11, 2009 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-19947178

RESUMEN

The goal of this study is to contribute to a better knowledge of certain species providing Non Woody Forest Products (NWFP) in the Centre East of Burkina Faso. This study aims to determine the state of the resources in Vitellaria paradoxa, Balanites aegyptiaca, Tamarindus indica and Lannea microcarpa. For this purpose, an inventory of the vegetation was carried out in circular pieces of land of 1250 m2, as a sample of the zone of work, based on the chart of occupation of the grounds. We are identified 158 species comprising 90 genera and 47 families. Those species represent more than 90% of the trees from which various parts are used in food, traditional pharmacopeia and the craft industry. We also showed that because of the strong anthropisation of the zone, the bad pedoclimatic conditions and the permanent bush fires, the regeneration and growth of Vitellaria paradoxa, Balanites aegyptiaca, Tamarindus indica and Lannea microcarpa are disturbed.


Asunto(s)
Plantas , Árboles , Anacardiaceae/anatomía & histología , Anacardiaceae/clasificación , Balanites/anatomía & histología , Balanites/clasificación , Burkina Faso , Ecosistema , Geografía , Humanos , Plantas/anatomía & histología , Plantas/clasificación , Tamarindus/anatomía & histología , Tamarindus/clasificación
4.
Pak J Biol Sci ; 12(19): 1287-98, 2009 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-20387743

RESUMEN

The present research focused on the inventory and the use of plants in traditional medicine for the treatment of diseases in this area. The method was based on ethnobotanical surveys with semi-directing interview, conducted from November 2006 to December 2007 among a sample of 50 people aged between 40 and 80 years and very experienced in traditional medicine in the municipalities of Bissiga, Lalgaye and Tenkodogo. We identify 73 phytogenetic species and 175 therapeutic indications used to treat 52 diseases and the principal ones are the gastrointestinal diseases, the malaria, the various fevers, the jaundice, the skin diseases, the respiratory affections, the reproduction diseases, the hemorrhoids and the infantile diseases. In traditional veterinary pharmacopoeia, 18 phytogenetic species are used with 33 therapeutic indications to treat diseases including trypanosomiasis, tuberculosis, diarrheas and wounds. The interest of people of this area for medicinal plants, command a special attention to organize the actors and preserve the plant genetic resources.


Asunto(s)
Medicinas Tradicionales Africanas/métodos , Plantas Medicinales , Adulto , Anciano , Burkina Faso , Medicina de Hierbas , Humanos , Persona de Mediana Edad , Farmacopeas como Asunto , Fitoterapia/métodos , Extractos Vegetales/uso terapéutico
5.
Pak J Biol Sci ; 12(3): 264-9, 2009 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-19579956

RESUMEN

In this study, the antioxidant and antibacterial activities of acetone extract, ethyl acetate, n-butanol and n-hexane fractions of acetone extract from leaves of Combretum nioroense Aubrév. ex Keay were investigated. The total phenolics and total flavonoids contents in the fractions and acetone extract were determined by spectrophotometric methods using Folin-Ciocalteu and AlCl3, respectively. Two methods were adopted to assess the antioxidant activities: the Ferric Reducing Antioxidant Power (FRAP) and the radical scavenging activity of 2, 2'-azinobis (3-ethylbenzothiozoline-6-sulfonate) radical cation (ABTS). The Minimum Inhibitory Concentrations (MICs) of the extract and fractions against pathogenic bacteria (4) and serotyped bacteria (4) from American Type Culture Collection (ATCC) were also determined using the agar-well diffusion method. The results showed that the butanol fraction, with the highest phenolic content, exhibited the best antioxidant and antibacterial activities as compared to the ethyl acetate fraction which contains more flavonoids.


Asunto(s)
Antibacterianos/farmacología , Antioxidantes/farmacología , Bacterias/efectos de los fármacos , Combretum/química , Combretum/anatomía & histología , Flavonoides/química , Depuradores de Radicales Libres/farmacología , Pruebas de Sensibilidad Microbiana , Fenoles/química , Hojas de la Planta/química
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