Detalles de la búsqueda
1.
The molecular basis of dapsone activation of CYP2C9-catalyzed nonsteroidal anti-inflammatory drug oxidation.
J Biol Chem;
299(12): 105368, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37866634
2.
Binding of SEP-363856 within TAAR1 and the 5HT1A receptor: implications for the design of novel antipsychotic drugs.
Mol Psychiatry;
27(1): 88-94, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34376825
3.
Binding of clozapine to the GABAB receptor: clinical and structural insights.
Mol Psychiatry;
25(9): 1910-1919, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32203158
4.
Proton Pump Inhibitors and Survival in Patients With Colorectal Cancer Receiving Fluoropyrimidine-Based Chemotherapy.
J Natl Compr Canc Netw;
19(9): 1037-1044, 2021 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33951613
5.
Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity.
Mol Pharmacol;
98(6): 710-718, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33008919
6.
Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen.
J Pharmacol Exp Ther;
374(3): 438-451, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32554434
7.
Multiorgan Immune-Related Adverse Events During Treatment With Atezolizumab.
J Natl Compr Canc Netw;
18(9): 1191-1199, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32886899
8.
Computational Prediction of the Site(s) of Metabolism and Binding Modes of Protein Kinase Inhibitors Metabolized by CYP3A4.
Drug Metab Dispos;
47(6): 616-631, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30902802
9.
Drug and Chemical Glucosidation by Control Supersomes and Membranes from Spodoptera frugiperda (Sf) 9 Cells: Implications for the Apparent Glucuronidation of Xenobiotics by UDP-glucuronosyltransferase 1A5.
Drug Metab Dispos;
47(3): 271-278, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30541877
10.
Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity.
Eur J Clin Pharmacol;
75(9): 1211-1218, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31123759
11.
Advances in drug metabolism and pharmacogenetics research in Australia.
Pharmacol Res;
116: 7-19, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27956261
12.
In vitro metabolism of the anti-inflammatory clerodane diterpenoid polyandric acid A and its hydrolysis product by human liver microsomes and recombinant cytochrome P450 and UDP-glucuronosyltransferase enzymes.
Xenobiotica;
47(6): 461-469, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-27412850
13.
Impaired dacarbazine activation and 7-ethoxyresorufin deethylation in vitro by polymorphic variants of CYP1A1 and CYP1A2: implications for cancer therapy.
Pharmacogenet Genomics;
26(10): 453-61, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27428168
14.
Warfarin resistance associated with genetic polymorphism of VKORC1: linking clinical response to molecular mechanism using computational modeling.
Pharmacogenet Genomics;
26(1): 44-50, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26513304
15.
Cytochrome P450 structure-function: insights from molecular dynamics simulations.
Drug Metab Rev;
48(3): 434-52, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27167388
16.
Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition.
Drug Metab Dispos;
44(3): 378-88, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26669329
17.
A Fragment-Based Approach for the Computational Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes.
Drug Metab Dispos;
44(11): 1794-1798, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27543205
18.
Scaling factors for the in vitro-in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance.
Br J Clin Pharmacol;
81(6): 1153-64, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26808419
19.
Insights into the UDP-sugar selectivities of human UDP-glycosyltransferases (UGT): a molecular modeling perspective.
Drug Metab Rev;
47(3): 335-45, 2015 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26289097
20.
Insights into the UDP-sugar selectivities of human UDP-glycosyltransferases (UGT): a molecular modeling perspective.
Drug Metab Rev;
: 1-11, 2015 Aug 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-26234632