RESUMEN
OBJECTIVE: Several studies performed in Spain have reported iodine deficiency in pregnant women but data from Valencia are lacking. The aim of the present study was to determine the degree of implantation of iodine supplementation in pregnant women in our health area. PATIENTS AND METHOD: A total of 232 pregnant women were studied in the first trimester of pregnancy. Thyroid-stimulating hormone (TSH), free thyroxine, and antiperoxidase antibodies were measured. A survey was performed on intake of iodized salt and pharmacological iodine supplements. Neonatal TSH concentrations were measured, based on screening of metabolopathies, in the newborns of participating women. RESULTS: Then mean age was 30.5+/-4.4 years. A total of 60.8% of the women consumed iodized salt, 51.3% took iodine polyvitamins and only 14.2% consumed potassium iodide. The median urinary iodine concentration was 100 microg/l; 66% had urinary iodine concentrations below the recommended level (150 microg/l). A positive association was found between pharmacological iodine intake and urinary iodine (p=0.016). Ten percent of the women had mild hypothyroxinemia, while 5.7% of the newborns had elevated TSH levels. CONCLUSIONS: Iodine intake in pregnant women in our health area is low, despite current recommendations. Our data support the need to promote the use of iodized salt in every home and to systematically administer potassium iodide supplements in all pregnant women.
Asunto(s)
Yodo/deficiencia , Primer Trimestre del Embarazo/sangre , Adulto , Autoanticuerpos/sangre , Suplementos Dietéticos , Utilización de Medicamentos , Desarrollo Embrionario , Femenino , Sangre Fetal/química , Enfermedades Fetales/prevención & control , Humanos , Recién Nacido , Yodo/orina , Necesidades Nutricionales , Yoduro de Potasio , Embarazo , Estudios Prospectivos , Cloruro de Sodio Dietético , Tirotropina/sangre , Tiroxina/sangre , VitaminasRESUMEN
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Asunto(s)
Laboratorios de Hospital/normas , Técnicas de Laboratorio Clínico/normas , Servicios Laboratoriales de Salud Publica , Ensayos de Aptitud de LaboratoriosRESUMEN
El Programa de Evaluación Externa de la Calidad de los Laboratorios Clínicos de la Comunidad Valenciana (EECLCCV) fomenta la calidad y transferibilidad de los resultados de los laboratorios participantes, informando de su calidad analítica y grado de homogeneidad de sus resultados. El presente artículo describe su origen y funcionamiento y su reciente transformación usando tecnología Web, que ha permitido su expansión en cuanto a número de laboratorios, tipos análisis, muestras, etc. gracias a su gestión automática (AU)
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Asunto(s)
Laboratorios de Hospital/normas , Técnicas de Laboratorio Clínico/normas , Ensayos de Aptitud de Laboratorios/organización & administración , Servicios ExternosRESUMEN
Objetivo: diversos estudios realizados en España demuestran una ingesta deficiente de yodo en gestantes, pero no hay datos de la Comunidad Valenciana. Se busca conocer el grado de implantación de la toma de suplementos de yodo en gestantes de nuestra área sanitaria. Pacientes y método: Se ha estudiado a 232 mujeres en el primer trimestre de embarazo. Se midió tirotropina (TSH), tiroxina libre (T4l), anticuerpos antiperoxidasa y yoduria, y se encuestó sobre consumo de sal yodada y suplementos farmacológicos de yodo. Se recogió el valor de la TSH neonatal del cribado de metabolopatías en los recién nacidos de las mujeres participantes. Resultados: la media de edad fue 30,5 ± 4,4 años. el 60,8% consumía sal yodada, el 51,3% tomaba polivitamínico con yodo, y sólo el 14,2% tomaba yoduro potásico. la mediana de las yodurias fue de 100 µg/l. el 66% tenía yodurias por debajo de la recomendada (150 µg/l). la relación entre ingesta farmacológica de yodo y yoduria fue positiva y significativa (p = 0,016). Presentaron una hipotiroxinemia leve el 10% de las mujeres. el 5,7% de los recién nacidos tenían una TSH elevada. Conclusiones: la ingesta de yodo de nuestras gestantes es baja, a pesar de las recomendaciones vigentes. los datos respaldan la necesidad de potenciar el uso de sal yodada en todos los hogares y administrar sistemáticamente un suplemento con yoduro potásico a toda mujer embarazada (AU)
Objective: Several studies performed in Spain have reported iodine deficiency in pregnant women but data from Valencia are lacking. The aim of the present study was to determine the degree of implantation of iodine supplementation in pregnant women in our health area. Patients and method: A total of 232 pregnant women were studied in the first trimester of pregnancy. Thyroid-stimulating hormone (TSH), free thyroxine, and antiperoxidase antibodies were measured. A survey was performed on intake of iodized salt and pharmacological iodine supplements. Neonatal TSH concentrations were measured, based on screening of metabolopathies, in the newborns of participating women. Results: Then mean age was 30.5 ± 4.4 years. A total of 60.8% of the women consumed iodized salt, 51.3% took iodine polyvitamins and only 14.2% consumed potassium iodide. The median urinary iodine concentration was 100 µg/l; 66% had urinary iodine concentrations below the recommended level (150 µg/l). A positive association was found between pharmacological iodine intake and urinary iodine (p = 0.016). Ten percent of the women had mild hypothyroxinemia, while 5.7% of the newborns had elevated TSH levels. Conclusions: Iodine intake in pregnant women in our health area is low, despite current recommendations. Our data support the need to promote the use of iodized salt in every home and to systematically administer potassium iodide supplements in all pregnant women (AU)