Comparison of natural ostiodilatation and endoscopic sinus surgery in the same patient with chronic sinusitis.

INTRODUCTION: Chronic rhinosinusitis is a broad clinical syndrome characterized by mucosal inflammation of the nose and paranasal sinuses. In order for the paranasal sinuses to maintain their physiological functions; the ostiomeatal complex drainage pathways must be open. Surgical procedures are an important treatment option in patients who do not respond adequately to medical treatment. Although the methods and instruments used in functional endoscopic sinus surgery have continued to improve in recent years, the scar tissue formed during operation disrupts the drainage of the sinuses and reduces postoperative success. The natural ostiodilatation method, which is performed by balloon sinoplasty method, has become more and more popular in recent years. OBJECTIVES: To compare the technique of balloon sinoplasty with the classical functional endoscopic sinus surgery method by considering the severity of chronic sinusitis on the same patient. METHODS: Total of 61 chronic sinusitis patients was included in the study. Paranasal sinus tomography of the patients was taken and according to the Lund-Mackay scoring, chronic sinusitis levels were determined. Cases were divided into two groups: Group 1 (severe chronic sinusitis group) and Group 2 (mild chronic sinusitis). RESULTS: There was no statistically significant difference in the results of comparison of sinuses which underwent balloon sinoplasty and classical functional endoscopic sinus surgery in Group 2 after Lund-Mackay scores. However in Group 1, the results of the comparison of postoperative Lund-Mackay scores of the balloon sinoplasty and the classical endoscopic operation were statistically significantly lower than those of the face half operated with the classical functional endoscopic sinus surgery. CONCLUSION: The success of balloon sinoplasty in patients with mild sinusitis is the same as in classic functional endoscopic sinus surgery. However, as the severity of sinusitis increases, the efficacy of balloon sinoplasty decreases.

A novel method for evaluation of oxidative stress in children with OSA.

OBJECTIVES: To evaluate the role of adenotonsillar hypertrophy and the outcomes of adenotonsillectomy (AT) on oxidative stress for obstructive sleep apnea (OSA) in children using a new method; thiol/disulfide homeostasis. METHODS: The study is consisted of 45 children with OSA and 38 healthy control subjects with similar age and sex. Children 3-12 years of age with OSA, defined as having an apnea/hypopnea index (AHI) of 5 or more in an overnight polysomnography, underwent adenotonsillectomy. OSA was classified as mild (1 ≤ AHI<10), moderate (10 ≤ AHI<20) or severe (AHI≥20). Venous blood samples were taken preoperatively and one month after surgery. The blood levels of thiol/disulfide homeostasis were assessed and compared between patients and control group, before and after adenotonsillectomy. RESULTS: Body mass index (BMI), mean age and gender distribution were similar between the study and control groups. Statistically significant higher disulfide levels and ratios were found in the study group compared to the control group; in patients with moderate to severe OSA compared to mild OSA; in the preoperative period compared to postoperative period (p < 0.001, for all). CONCLUSIONS: The current study provides preliminary evidence between oxidative stress and OSA in children with adenotonsillar. Adenotonsillectomy for OSA may result in a dramatic improvement in oxidative stress as measured by thiol/disulfide homeostasis.