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1.
Gan To Kagaku Ryoho ; 46(3): 511-514, 2019 Mar.
Artículo en Japonés | MEDLINE | ID: mdl-30914598

RESUMEN

A 43-year-old man was diagnosed with gastric cancer with diaphragm invasion and multiple lymph node metastases and underwent total gastrectomy. The histological diagnosis was por2>tub2, ypT4b(diaphragm), int, INF c, ly1, v1, ypN3, yp Stage ⅢC. Three months postoperatively, computed tomography showed recurrence in the peritoneum and multiple lymph nodes, and he received chemotherapy(RAM plus PTX). After initiating the third course of chemotherapy, he was hospitalized due to loss of appetite and fatigue. On the third day of hospitalization, he lost consciousness and had a temporary convulsion seizure. Thereafter, he complained of headache and nausea. Brain magnetic resonance imaging and cerebrospinal fluid examination lead to a diagnosis of carcinomatous meningitis due to gastric cancer. An Ommaya reservoir was placed, and intrathecal infusion with methotrexate(MTX)and cytarabine(Ara-C)was planned; however, intrathecal infusion could not be administered because of hepatic injury due to acute obstructive cholangitis. He died 6 months postoperatively. Carcinomatous meningitis has a rapidly progressive course with very poor prognosis. Early diagnosis is important, and the treatment should be initiated as soon as possible. Moreover, an effective standard treatment for carcinomatous meningitis needs to be established.


Asunto(s)
Carcinomatosis Meníngea , Neoplasias Gástricas , Adulto , Citarabina , Humanos , Masculino , Carcinomatosis Meníngea/etiología , Metotrexato , Recurrencia Local de Neoplasia , Neoplasias Gástricas/complicaciones
2.
Gan To Kagaku Ryoho ; 42(12): 1553-5, 2015 Nov.
Artículo en Japonés | MEDLINE | ID: mdl-26805093

RESUMEN

We investigated the efficacy of different biliary drainage methods for the treatment of unresectable cholangiocarcinomas. We performed a retrospective study of 28 patients with unresectable cholangiocarcinomas who underwent biliary drainage at our hospital between January 2008 and June 2014 to compare the incidence of post-drainage stent dysfunction (SD) and reintervention (RI) for SD according to primary drainage method, lesion site, and complication status (the presence or absence of cholangitis). The duration of stent patency was compared between the different stent types. No significant differences in the incidence of SD and RI were found according to primary drainage methods, lesion site, or the presence or absence of cholangitis. The mean durations of stent patency for plastic and metal stents were 2.7 months and 7.4 months, respectively, suggesting that metal stents should be selected when the estimated prognosis is ≥2 months. Furthermore, metal stent placement, rather than the additional placement of plastic stents, should be considered a feasible option in cases of SD.


Asunto(s)
Neoplasias de los Conductos Biliares , Colangiocarcinoma , Drenaje , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pronóstico , Stents
3.
Asian J Endosc Surg ; 14(4): 807-810, 2021 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-33847436

RESUMEN

Laparoscopic ventral hernia repair with intraperitoneal onlay mesh reinforcement is often performed in clinical practice. We herein describe a patient who developed a Spigelian hernia at the edge of the mesh due to rupture of the muscular layer in the abdominal wall. A 69-year-old woman developed a left-sided abdominal bulge 15 months after laparoscopic ventral hernia repair. CT showed a 33-mm defect in the abdominal wall at the lateral edge of the left abdominal rectus muscle with an intestinal prolapse through the defect. She was diagnosed with a Spigelian hernia and underwent operation. The hernia orifice was located at the aponeurosis of the transverse abdominal muscle where the thread had been used to fix the mesh through all layers of the abdominal wall. This report details a case of a Spigelian hernia after laparoscopic ventral hernia repair.


Asunto(s)
Pared Abdominal , Hernia Ventral , Hernia Incisional , Laparoscopía , Músculos Abdominales , Pared Abdominal/cirugía , Anciano , Femenino , Hernia Ventral/cirugía , Herniorrafia/efectos adversos , Humanos , Hernia Incisional/etiología , Hernia Incisional/cirugía , Mallas Quirúrgicas/efectos adversos
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