Detalles de la búsqueda
1.
New Facets of DNA Double Strand Break Repair: Radiation Dose as Key Determinant of HR versus c-NHEJ Engagement.
Int J Mol Sci;
24(19)2023 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37834403
2.
Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52.
Nucleic Acids Res;
48(4): 1905-1924, 2020 02 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-31832684
3.
PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.
Int J Mol Sci;
23(21)2022 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36361678
4.
Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination.
Int J Mol Sci;
23(16)2022 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36012445
5.
DNA Damage Clustering after Ionizing Radiation and Consequences in the Processing of Chromatin Breaks.
Molecules;
27(5)2022 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35268641
6.
Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA.
Int J Mol Sci;
22(20)2021 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34681628
7.
Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages.
J Lipid Res;
60(3): 506-515, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30655318
8.
Abdominopelvic 1.5-T and 3.0-T MR Imaging in Healthy Volunteers: Relationship to Formation of DNA Double-Strand Breaks.
Radiology;
288(2): 529-535, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29714683
9.
Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment.
Nucleic Acids Res;
44(16): 7673-90, 2016 09 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27257076
10.
Processing-Challenges Generated by Clusters of DNA Double-Strand Breaks Underpin Increased Effectiveness of High-LET Radiation and Chromothripsis.
Adv Exp Med Biol;
1044: 149-168, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29956296
11.
DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation.
Semin Cancer Biol;
37-38: 51-64, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27016036
12.
The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated protein.
Hum Mol Genet;
21(18): 4038-48, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22694955
13.
Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells.
Nucleic Acids Res;
40(6): 2599-610, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22127868
14.
Conformational transitions of proteins engaged in DNA double-strand break repair, analysed by tryptophan fluorescence emission and FRET.
Biochem J;
443(3): 701-9, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22338600
15.
The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.
Cells;
12(10)2023 05 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37408221
16.
Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells.
Cells;
12(11)2023 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37296650
17.
The high toxicity of DSB-clusters modelling high-LET-DNA damage derives from inhibition of c-NHEJ and promotion of alt-EJ and SSA despite increases in HR.
Front Cell Dev Biol;
10: 1016951, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36263011
18.
BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.
Cancers (Basel);
14(22)2022 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36428712
19.
Increased Resection at DSBs in G2-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.
Cells;
11(13)2022 07 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35805183
20.
Selective vulnerability of ARID1A deficient colon cancer cells to combined radiation and ATR-inhibitor therapy.
Front Oncol;
12: 999626, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36249060