Detalles de la búsqueda
1.
Modeling gain-of-function and loss-of-function components of SPAST-based hereditary spastic paraplegia using transgenic mice.
Hum Mol Genet;
31(11): 1844-1859, 2022 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34935948
2.
Identifying potential imaging markers for diffusion property changes in a mouse model of amyotrophic lateral sclerosis: Application of the continuous time random walk model to ultrahigh b-value diffusion-weighted MR images of spinal cord tissue.
NMR Biomed;
37(1): e5037, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37721118
3.
Toxic effects of mutant huntingtin in axons are mediated by its proline-rich domain.
Brain;
2023 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37633260
4.
Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism.
J Neurosci;
41(45): 9431-9451, 2021 11 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34607969
5.
Hereditary spastic paraplegia: gain-of-function mechanisms revealed by new transgenic mouse.
Hum Mol Genet;
28(7): 1136-1152, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30520996
6.
Mutant spastin proteins promote deficits in axonal transport through an isoform-specific mechanism involving casein kinase 2 activation.
Hum Mol Genet;
26(12): 2321-2334, 2017 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28398512
7.
Detection of axonal degeneration in a mouse model of Huntington's disease: comparison between diffusion tensor imaging and anomalous diffusion metrics.
MAGMA;
32(4): 461-471, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30771034
8.
Tau and Axonal Transport Misregulation in Tauopathies.
Adv Exp Med Biol;
1184: 81-95, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-32096030
9.
Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases.
Neurobiol Dis;
105: 273-282, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28411118
10.
Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease.
Hum Mol Genet;
24(18): 5285-98, 2015 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26123489
11.
The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3ß and deregulation of molecular motors.
J Neurosci;
33(24): 10048-56, 2013 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-23761900
12.
Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.
Brain;
135(Pt 7): 2058-73, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22719003
13.
Genetic deletion of c-Jun amino-terminal kinase 3 (JNK3) modestly increases disease severity in a mouse model of multiple sclerosis.
J Neuroimmunol;
382: 578152, 2023 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37454525
14.
Divergent Molecular Pathways for Toxicity of Selected Mutant C9ORF72-derived Dipeptide Repeats.
bioRxiv;
2023 Sep 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-37808871
15.
Axon-Autonomous Effects of the Amyloid Precursor Protein Intracellular Domain (AICD) on Kinase Signaling and Fast Axonal Transport.
Cells;
12(19)2023 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37830617
16.
Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases.
J Neurosci;
31(27): 9858-68, 2011 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-21734277
17.
Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells.
Exp Brain Res;
217(3-4): 353-64, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21960299
18.
Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.
Biochemistry;
50(47): 10300-10, 2011 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-22039833
19.
Therapeutic Strategies for Mutant SPAST-Based Hereditary Spastic Paraplegia.
Brain Sci;
11(8)2021 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34439700
20.
Engagement of Neurotropic Viruses in Fast Axonal Transport: Mechanisms, Potential Role of Host Kinases and Implications for Neuronal Dysfunction.
Front Cell Neurosci;
15: 684762, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34234649