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1.

The IRX(3)some factor in macrophages.

Moynagh, Paul N; Hogan, Andrew E.

Nat Immunol; 22(10): 1203-1204, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34556882

2.

Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation.

Wu, Yuqing; Hu, Yingchao; Wang, Bingwei; Li, Sheng; Ma, Chunmei; Liu, Xue; Moynagh, Paul N; Zhou, Jiawei; Yang, Shuo.

Mol Cell; 78(1): 42-56.e6, 2020 04 02.

Artículo en Inglés | MEDLINE | ID: mdl-32035036

3.

IL-15 in autoimmunity and cancer: O-tu-b or not O-tu-b?

Moynagh, Paul N.

Nat Immunol; 20(7): 780-782, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31182806

4.

Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.

Yang, Shuo; Wang, Bingwei; Humphries, Fiachra; Jackson, Ruaidhri; Healy, Marc E; Bergin, Ronan; Aviello, Gabriella; Hall, Barry; McNamara, Deirdre; Darby, Trevor; Quinlan, Aoife; Shanahan, Fergus; Melgar, Silvia; Fallon, Padraic G; Moynagh, Paul N.

Nat Immunol; 14(9): 927-36, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-23892723

5.

The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11.

Hu, Yingchao; Jiang, Yuying; Li, Sheng; Ma, Xiaoqing; Chen, Min; Yang, Rui; Wen, Shuang; Moynagh, Paul N; Wang, Bingwei; Hu, Gang; Yang, Shuo.

Proc Natl Acad Sci U S A; 119(45): e2210809119, 2022 11 08.

Artículo en Inglés | MEDLINE | ID: mdl-36322773

6.

Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons.

Siednienko, Jakub; Jackson, Ruaidhri; Mellett, Mark; Delagic, Nezira; Yang, Shuo; Wang, Bingwei; Tang, Lisa S; Callanan, John J; Mahon, Bernard P; Moynagh, Paul N.

Nat Immunol; 13(11): 1055-62, 2012 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-23042151

7.

Peli1 (rel)ieves autoimmunity.

Moynagh, Paul N.

Nat Immunol; 12(10): 927-9, 2011 Sep 20.

Artículo en Inglés | MEDLINE | ID: mdl-21934671

8.

The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance.

Yang, Shuo; Wang, Bingwei; Humphries, Fiachra; Hogan, Andrew E; O'Shea, Donal; Moynagh, Paul N.

Immunity; 41(6): 973-87, 2014 Dec 18.

Artículo en Inglés | MEDLINE | ID: mdl-25526310

9.

Dendritic Cell-Specific Role for Pellino2 as a Mediator of TLR9 Signaling Pathway.

Oleszycka, Ewa; Rodgers, Aoife M; Xu, Linan; Moynagh, Paul N.

J Immunol; 207(9): 2325-2336, 2021 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-34588221

10.

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses.

O'Brien, Aisling; Loftus, Roisin M; Pisarska, Marta M; Tobin, Laura M; Bergin, Ronan; Wood, Nicole A W; Foley, Cathriona; Mat, Arimin; Tinley, Frances C; Bannan, Ciaran; Sommerville, Gary; Veerapen, Natacha; Besra, Gurdyal S; Sinclair, Linda V; Moynagh, Paul N; Lynch, Lydia; Finlay, David K; O'Shea, Donal; Hogan, Andrew E.

J Immunol; 202(12): 3404-3411, 2019 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-31076528

11.

Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity.

Humphries, Fiachra; Moynagh, Paul N.

Immunol Rev; 266(1): 93-108, 2015 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-26085209

12.

Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins.

Smith, Sinéad M; Freeley, Michael; Moynagh, Paul N; Kelleher, Dermot P.

Helicobacter; 22(1)2017 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-27302665

13.

Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling.

van Gent, Michiel; Braem, Steven G E; de Jong, Annemieke; Delagic, Nezira; Peeters, Janneke G C; Boer, Ingrid G J; Moynagh, Paul N; Kremmer, Elisabeth; Wiertz, Emmanuel J; Ovaa, Huib; Griffin, Bryan D; Ressing, Maaike E.

PLoS Pathog; 10(2): e1003960, 2014 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-24586164

14.

Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.

Hanuszkiewicz, Anna; Pittock, Paula; Humphries, Fiachra; Moll, Hermann; Rosales, Amanda Roa; Molinaro, Antonio; Moynagh, Paul N; Lajoie, Gilles A; Valvano, Miguel A.

J Biol Chem; 289(27): 19231-44, 2014 Jul 04.

Artículo en Inglés | MEDLINE | ID: mdl-24841205

15.

Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse.

Anderson, Seán T; Commins, Seán; Moynagh, Paul N; Coogan, Andrew N.

Brain Behav Immun; 43: 98-109, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25063709

16.

The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-ß expression via peroxisome proliferator-activated receptor-α.

Downer, Eric J; Clifford, Eileen; Amu, Sylvie; Fallon, Padraic G; Moynagh, Paul N.

J Biol Chem; 287(30): 25440-53, 2012 Jul 20.

Artículo en Inglés | MEDLINE | ID: mdl-22654113

17.

Mal mediates TLR-induced activation of CREB and expression of IL-10.

Mellett, Mark; Atzei, Paola; Jackson, Ruaidhri; O'Neill, Luke A; Moynagh, Paul N.

J Immunol; 186(8): 4925-35, 2011 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-21398611

18.

ECSIT Is a Critical Factor for Controlling Intestinal Homeostasis and Tumorigenesis through Regulating the Translation of YAP Protein.

Jiang, Yuying; Ma, Chunmei; Hu, Yingchao; Yang, Yongbing; Ma, Chanyuan; Wu, Chunyan; Liu, Lu; Wen, Shuang; Moynagh, Paul N; Wang, Bingwei; Yang, Shuo.

Adv Sci (Weinh); 10(25): e2205180, 2023 09.

Artículo en Inglés | MEDLINE | ID: mdl-37409430

19.

The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-ß expression via peroxisome proliferator-activated receptor-α.

Downer, Eric J; Clifford, Eileen; Amu, Sylvie; Fallon, Padraic G; Moynagh, Paul N.

J Biol Chem; 291(4): 1604, 2016 Jan 22.

Artículo en Inglés | MEDLINE | ID: mdl-26802138

20.

Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis.

Downer, Eric J; Clifford, Eileen; Gran, Bruno; Nel, Hendrik J; Fallon, Padraic G; Moynagh, Paul N.

J Biol Chem; 286(12): 10316-28, 2011 Mar 25.

Artículo en Inglés | MEDLINE | ID: mdl-21245146

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The IRX(3)some factor in macrophages.

Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation.

IL-15 in autoimmunity and cancer: O-tu-b or not O-tu-b?

Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.

The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11.

Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons.

Peli1 (rel)ieves autoimmunity.

The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance.

Dendritic Cell-Specific Role for Pellino2 as a Mediator of TLR9 Signaling Pathway.

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses.

Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity.

Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins.

Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling.

Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.

Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse.

The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-ß expression via peroxisome proliferator-activated receptor-α.

Mal mediates TLR-induced activation of CREB and expression of IL-10.

ECSIT Is a Critical Factor for Controlling Intestinal Homeostasis and Tumorigenesis through Regulating the Translation of YAP Protein.

The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-ß expression via peroxisome proliferator-activated receptor-α.

Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis.